(Q36293491)

13 August 2017

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title

Determinants of specificity in coagulation proteases (English)

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13 August 2017

Page MJ

1

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13 August 2017

Macgillivray RT

series ordinal

2

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13 August 2017

Di Cera E

series ordinal

3

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13 August 2017

publication date

1 November 2005

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Journal of Thrombosis and Haemostasis

13 August 2017

published in

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13 August 2017

volume

3

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13 August 2017

issue

11

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13 August 2017

page(s)

2401-2408

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MEROPS: the peptidase database.

13 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2005.01456.X

Substrate recognition drives the evolution of serine proteases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2005.01456.X

Structure of human factor D. A complement system protein at 2.0 A resolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2005.01456.X

Human beta-tryptase is a ring-like tetramer with active sites facing a central pore

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2005.01456.X

Residue 225 determines the Na(+)-induced allosteric regulation of catalytic activity in serine proteases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2005.01456.X

Molecular markers of serine protease evolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2005.01456.X

On the size of the active site in proteases. I. Papain

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2005.01456.X

The assembly of the factor X-activating complex on activated human platelets

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2005.01456.X

Exosite-dependent regulation of the protein C anticoagulant pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2005.01456.X

Rapid and general profiling of protease specificity by using combinatorial fluorogenic substrate libraries

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2005.01456.X

Serine protease mechanism and specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2005.01456.X

Serine proteases and their homologs in the Drosophila melanogaster genome: an initial analysis of sequence conservation and phylogenetic relationships

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2005.01456.X

Conservation of the modular structure of complement factor I through vertebrate evolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2005.01456.X

Structural origins of substrate discrimination in trypsin and chymotrypsin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2005.01456.X

Residue Asp-189 controls both substrate binding and the monovalent cation specificity of thrombin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2005.01456.X

Site-specific dissection of substrate recognition by thrombin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2005.01456.X

Structure of human des(1-45) factor Xa at 2.2 A resolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2005.01456.X

Converting blood coagulation factor IXa into factor Xa: dramatic increase in amidolytic activity identifies important active site determinants

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2005.01456.X

Crystal structure of the catalytic domain of human complement c1s: a serine protease with a handle

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2005.01456.X

Crystal structure of a prostate kallikrein isolated from stallion seminal plasma: a homologue of human PSA

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2005.01456.X

The distinct roles that Gln-192 and Glu-217 of factor IX play in selectivity for macromolecular substrates and inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2005.01456.X

Structural features of a snake venom thrombin-like enzyme: thrombin and trypsin on a single catalytic platform?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2005.01456.X

The structure of rat mast cell protease II at 1.9-A resolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2005.01456.X

Mutation of W215 compromises thrombin cleavage of fibrinogen, but not of PAR-1 or protein C.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2005.01456.X

ZZ made EZ: influence of inhibitor configuration on enzyme selectivity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2005.01456.X

Understanding protein-ligand interactions: the price of protein flexibility

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2005.01456.X

Conversion of thrombin into an anticoagulant by protein engineering

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2005.01456.X

Engineered recombinant factor VII Q217 variants with altered inhibitor specificities.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2005.01456.X

Molecular dissection of Na+ binding to thrombin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2005.01456.X

Importance of the prime subsites of the C1s protease of the classical complement pathway for recognition of substrates

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2005.01456.X

Crystal structures of uninhibited factor VIIa link its cofactor and substrate-assisted activation to specific interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2005.01456.X

The dynamics of thrombin formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2005.01456.X

Identification of surface residues mediating tissue factor binding and catalytic function of the serine protease factor VIIa

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2005.01456.X

The thrombin epitope recognizing thrombomodulin is a highly cooperative hot spot in exosite I.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2005.01456.X

Functional mapping of the surface residues of human thrombin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2005.01456.X

Thrombomodulin changes the molecular surface of interaction and the rate of complex formation between thrombin and protein C.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2005.01456.X

Structural basis for the anticoagulant activity of the thrombin-thrombomodulin complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2005.01456.X

Domains specifying thrombin–receptor interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2005.01456.X

Thrombin signalling and protease-activated receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2005.01456.X

Protease-activated receptor 3 is a second thrombin receptor in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2005.01456.X

The elusive role of the potential factor X cation-binding exosite-1 in substrate and inhibitor interactions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2005.01456.X

Binding of substrate in two conformations to human prothrombinase drives consecutive cleavage at two sites in prothrombin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2005.01456.X

Heparin activates antithrombin anticoagulant function by generating new interaction sites (exosites) for blood clotting proteinases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2005.01456.X

Serpin structure, mechanism, and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2005.01456.X

Exosite-interactive regions in the A1 and A2 domains of factor VIII facilitate thrombin-catalyzed cleavage of heavy chain

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2005.01456.X

Molecular determinants of the mechanism underlying acceleration of the interaction between antithrombin and factor Xa by heparin pentasaccharide

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2005.01456.X

Exosite occupation by heparin enhances the reactivity of blood coagulation factor IXa.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2005.01456.X

The critical role of the 185-189-loop in the factor Xa interaction with Na+ and factor Va in the prothrombinase complex.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2005.01456.X

Exosite-driven substrate specificity and function in coagulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2005.01456.X

Thrombin is a Na(+)-activated enzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2005.01456.X

Sodium binding site of factor Xa: role of sodium in the prothrombinase complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2005.01456.X

Prothrombinase assembly and S1 site occupation restore the catalytic activity of FXa impaired by mutation at the sodium-binding site

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2005.01456.X

Thermodynamic linkage between the S1 site, the Na+ site, and the Ca2+ site in the protease domain of human activated protein C (APC). Sodium ion in the APC crystal structure is coordinated to four carbonyl groups from two separate loops

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2005.01456.X

Evolutionary divergence of substrate specificity within the chymotrypsin-like serine protease fold

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2005.01456.X

The molecular environment of the Na+ binding site of thrombin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2005.01456.X

Thermodynamics of Na+ binding to coagulation serine proteases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2005.01456.X

Prothrombin Salakta: substitution of glutamic acid-466 by alanine reduces the fibrinogen clotting activity and the esterase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2005.01456.X

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2005.01456.X

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2005.01456.X

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2005.01456.X

21 January 2018

Thrombin interactions

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2005.01456.X

Gating of thrombin in platelet aggregates by pO2-linked lowering of extracellular Ca2+ concentration

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2005.01456.X

Evolution of enzyme cascades from embryonic development to blood coagulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2005.01456.X

Attempts to convert chymotrypsin to trypsin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2005.01456.X

10.1111/J.1538-7836.2005.01456.X

21 January 2018

Identifiers

DOI

1 reference

13 August 2017

1 reference