(Q36298496)

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The endocannabinoid, anandamide, augments Notch-1 signaling in cultured cortical neurons exposed to amyloid-β and in the cortex of aged rats

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scholarly article

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11 February 2020

The endocannabinoid, anandamide, augments Notch-1 signaling in cultured cortical neurons exposed to amyloid-β and in the cortex of aged rats (English)

1 reference

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11 February 2020

endocannabinoids

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5

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11 February 2020

author name string

Riffat Tanveer

1

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11 February 2020

Aoife Gowran

2

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11 February 2020

Janis Noonan

3

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11 February 2020

Sinead E Keating

4

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11 February 2020

Veronica A Campbell

6

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11 February 2020

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13 August 2012

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11 February 2020

Journal of Biological Chemistry

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11 February 2020

287

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11 February 2020

41

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11 February 2020

34709-34721

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22891244%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

The fatty acid amide hydrolase inhibitor URB597 exerts anti-inflammatory effects in hippocampus of aged rats and restores an age-related deficit in long-term potentiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3464574

30 September 2017

The physiology of the β-amyloid precursor protein intracellular domain AICD.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3464574

30 September 2017

Mutations in nicastrin protein differentially affect amyloid beta-peptide production and Notch protein processing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3464574

30 September 2017

The role of Notch signaling in adult neurogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3464574

30 September 2017

Breast cancer stem cells: something out of notching?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3464574

30 September 2017

Endocannabinoids prevent β-amyloid-mediated lysosomal destabilization in cultured neurons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3464574

30 September 2017

Targeting Notch to target cancer stem cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3464574

30 September 2017

Opposing actions of endocannabinoids on cholangiocarcinoma growth is via the differential activation of Notch signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3464574

30 September 2017

gamma-Secretase dependent production of intracellular domains is reduced in adult compared to embryonic rat brain membranes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3464574

30 September 2017

Biological and clinical implications of nicastrin expression in invasive breast cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3464574

30 September 2017

p53 is regulated by and regulates members of the gamma-secretase complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3464574

30 September 2017

Alzheimer's disease and Notch signaling.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3464574

30 September 2017

Neurogenesis and Alzheimer's disease: at the crossroads

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3464574

30 September 2017

Conditional forebrain inactivation of nicastrin causes progressive memory impairment and age-related neurodegeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3464574

30 September 2017

Notch: from neural development to neurological disorders

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3464574

30 September 2017

NUMB controls p53 tumour suppressor activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3464574

30 September 2017

Alzheimer's disease; taking the edge off with cannabinoids?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3464574

30 September 2017

Hippocampal neurogenesis during normal and pathological aging

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3464574

30 September 2017

Notch1 intracellular domain suppresses APP intracellular domain-Tip60-Fe65 complex mediated signaling through physical interaction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3464574

30 September 2017

Cellular distribution of gamma-secretase subunit nicastrin in the developing and adult rat brains

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3464574

30 September 2017

Dynamic regulation of mammalian numb by G protein-coupled receptors and protein kinase C activation: Structural determinants of numb association with the cortical membrane

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3464574

30 September 2017

Notch signalling regulates stem cell numbers in vitro and in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3464574

30 September 2017

Mechanisms of CB1 receptor signaling: endocannabinoid modulation of synaptic strength.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3464574

30 September 2017

Cannabinoid receptors as therapeutic targets.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3464574

30 September 2017

Roles of bHLH genes in neural stem cell differentiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3464574

30 September 2017

Notch to remember

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3464574

30 September 2017

Prevention of Alzheimer's disease pathology by cannabinoids: neuroprotection mediated by blockade of microglial activation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3464574

30 September 2017

Notch signaling in Drosophila long-term memory formation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3464574

30 September 2017

Involvement of Notch signaling in hippocampal synaptic plasticity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3464574

30 September 2017

Regulation of notch signaling activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3464574

30 September 2017

Learning and memory deficits in Notch mutant mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3464574

30 September 2017

Basic helix-loop-helix factors in cortical development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3464574

30 September 2017

HES and HERP families: multiple effectors of the Notch signaling pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3464574

30 September 2017

beta-Amyloid (1-40)-induced apoptosis of cultured cortical neurones involves calpain-mediated cleavage of poly-ADP-ribose polymerase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3464574

30 September 2017

Mammalian APH-1 interacts with presenilin and nicastrin and is required for intramembrane proteolysis of amyloid-beta precursor protein and Notch

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3464574

30 September 2017

PEN-2 is an integral component of the gamma-secretase complex required for coordinated expression of presenilin and nicastrin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3464574

30 September 2017

Proneural genes and the specification of neural cell types

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3464574

30 September 2017

The gamma-secretase-generated intracellular domain of beta-amyloid precursor protein binds Numb and inhibits Notch signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3464574

30 September 2017

Notch pathway molecules are essential for the maintenance, but not the generation, of mammalian neural stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3464574

30 September 2017

Impact of active dendrites and structural plasticity on the memory capacity of neural tissue

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3464574

30 September 2017

Neurogenesis in the adult is involved in the formation of trace memories

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3464574

30 September 2017

Nicastrin modulates presenilin-mediated notch/glp-1 signal transduction and betaAPP processing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3464574

30 September 2017

A novel proteolytic cleavage involved in Notch signaling: the role of the disintegrin-metalloprotease TACE

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3464574

30 September 2017

Clinical features of Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3464574

30 September 2017

Two transmembrane aspartates in presenilin-1 required for presenilin endoproteolysis and gamma-secretase activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3464574

30 September 2017

Signal transduction by the Wnt family of ligands

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3464574

30 September 2017

Signal transduction by activated mNotch: importance of proteolytic processing and its regulation by the extracellular domain.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3464574

30 September 2017

Targeted disruption of mammalian hairy and Enhancer of split homolog-1 (HES-1) leads to up-regulation of neural helix-loop-helix factors, premature neurogenesis, and severe neural tube defects

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3464574

30 September 2017

Nicastrin binds to membrane-tethered Notch

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3464574

29 June 2018

Does dysregulation of the Notch and wingless/Wnt pathways underlie the pathogenesis of Alzheimer's disease?

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.350678

21 January 2018

Notch-1 immunoexpression is increased in Alzheimer's and Pick's disease.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.350678

21 January 2018

Numb modifies neuronal vulnerability to amyloid beta-peptide in an isoform-specific manner by a mechanism involving altered calcium homeostasis: implications for neuronal death in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.350678

21 January 2018

Excess of nicastrin in brain results in heterozygosity having no effect on endogenous APP processing and amyloid peptide levels in vivo.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.350678

21 January 2018

Loss of nicastrin elicits an apoptotic phenotype in mouse embryos.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.350678

21 January 2018

Abeta-mediated activation of the apoptotic cascade in cultured cortical neurones: a role for cathepsin-L.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.350678

21 January 2018

Localization of the endocannabinoid-degrading enzyme fatty acid amide hydrolase in rat dorsal root ganglion cells and its regulation after peripheral nerve injury.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.350678

21 January 2018

Delta 9-tetrahydrocannabinol induces the apoptotic pathway in cultured cortical neurones via activation of the CB1 receptor.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.350678

21 January 2018

Regulation of neural progenitor cell fate by anandamide

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.350678

21 January 2018

Involvement of brain-derived neurotrophic factor in cannabinoid receptor-dependent protection against excitotoxicity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.350678

21 January 2018

Contact-dependent inhibition of cortical neurite growth mediated by notch signaling

1 reference

https://pubmed.ncbi.nlm.nih.gov/22891244

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A ligand-induced extracellular cleavage regulates gamma-secretase-like proteolytic activation of Notch1

1 reference

https://pubmed.ncbi.nlm.nih.gov/22891244

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Notch, a universal arbiter of cell fate decisions

1 reference

https://pubmed.ncbi.nlm.nih.gov/22891244

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M112.350678

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22891244%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22891244%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22891244%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

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