(Q36340868)

13 August 2017

Characterization of novel genomic alterations and therapeutic approaches using acute megakaryoblastic leukemia xenograft models (English)

1 reference

acute megakaryoblastic leukemia

13 August 2017

1 reference

1 reference

Olivier Bluteau

9

0 references

Thomas Mercher

Thomas Mercher

30

0 references

Arnaud Petit

Arnaud Petit

13

0 references

Stéphane de Botton

Stéphane de Botton

23

0 references

Daniel Gautheret

Daniel Gautheret

17

0 references

John D Crispino

John D Crispino

26

0 references

Cécile K Lopez

Cécile K Lopez

2

0 references

Beat C Bornhauser

Beat Bornhauser

16

0 references

Jean-Pierre Bourquin

Jean-Pierre Bourquin

25

0 references

William Vainchenker

21

William Vainchenker

1 reference

13 August 2017

15

Dirk Reinhardt

1 reference

13 August 2017

Clarisse Thiollier

1

1 reference

13 August 2017

Bastien Gerby

3

1 reference

13 August 2017

Cathy Ignacimouttou

4

1 reference

13 August 2017

Sandrine Poglio

5

1 reference

13 August 2017

Yannis Duffourd

6

1 reference

13 August 2017

Justine Guégan

7

1 reference

13 August 2017

Paola Rivera-Munoz

8

1 reference

13 August 2017

Vinciane Mabialah

10

1 reference

13 August 2017

M'boyba Diop

11

1 reference

13 August 2017

Qiang Wen

12

1 reference

13 August 2017

Anne-Laure Bauchet

14

1 reference

13 August 2017

Yann Lecluse

18

1 reference

13 August 2017

Judith Landman-Parker

19

1 reference

13 August 2017

Isabelle Radford

20

1 reference

13 August 2017

Nicole Dastugue

22

1 reference

13 August 2017

Philippe Dessen

24

1 reference

13 August 2017

Paola Ballerini

27

1 reference

13 August 2017

Olivier A Bernard

28

1 reference

13 August 2017

Françoise Pflumio

29

1 reference

13 August 2017

language of work or name

English

0 references

publication date

8 October 2012

1 reference

Journal of Experimental Medicine

13 August 2017

1 reference

13 August 2017

209

1 reference

13 August 2017

11

1 reference

13 August 2017

2017-2031

1 reference

Identification of regulators of polyploidization presents therapeutic targets for treatment of AMKL

13 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3478932

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3478932

Increased dosage of the chromosome 21 ortholog Dyrk1a promotes megakaryoblastic leukemia in a murine model of Down syndrome.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3478932

TopHat-Fusion: an algorithm for discovery of novel fusion transcripts

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3478932

The diverse functions of Dot1 and H3K79 methylation.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3478932

deFuse: an algorithm for gene fusion discovery in tumor RNA-Seq data

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3478932

Identification of nuclear localization, DNA binding, and transactivating mechanisms of Kruppel-like zinc finger protein Gli-similar 2 (Glis2)

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3478932

Differential expression analysis for sequence count data

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3478932

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3478932

Genomic analysis reveals few genetic alterations in pediatric acute myeloid leukemia

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3478932

Acute megakaryoblastic leukaemia (AMKL) and transient myeloproliferative disorder (TMD) in Down syndrome: a multi-step model of myeloid leukaemogenesis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3478932

Hedgehog signaling is dispensable for adult murine hematopoietic stem cell function and hematopoiesis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3478932

Hedgehog signaling is dispensable for adult hematopoietic stem cell function

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3478932

Haematopoietic malignancies caused by dysregulation of a chromatin-binding PHD finger

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3478932

Sonic hedgehog signaling regulates reciprocal epithelial-mesenchymal interactions controlling palatal outgrowth

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3478932

TopHat: discovering splice junctions with RNA-Seq

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3478932

The OTT-MAL fusion oncogene activates RBPJ-mediated transcription and induces acute megakaryoblastic leukemia in a knockin mouse model

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3478932

Insights into the manifestations, outcomes, and mechanisms of leukemogenesis in Down syndrome

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3478932

Activating mutations in human acute megakaryoblastic leukemia.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3478932

Kruppel-like zinc finger protein Glis2 is essential for the maintenance of normal renal functions

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3478932

Loss of GLIS2 causes nephronophthisis in humans and mice by increased apoptosis and fibrosis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3478932

Activating alleles of JAK3 in acute megakaryoblastic leukemia

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3478932

MPLW515L is a novel somatic activating mutation in myelofibrosis with myeloid metaplasia

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3478932

JAK2T875N is a novel activating mutation that results in myeloproliferative disease with features of megakaryoblastic leukemia in a murine bone marrow transplantation model

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3478932

Identification of distinct molecular phenotypes in acute megakaryoblastic leukemia by gene expression profiling.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3478932

Identification of NUP98 abnormalities in acute leukemia: JARID1A (12p13) as a new partner gene

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3478932

MLL-MLLT10 fusion gene in pediatric acute megakaryoblastic leukemia

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3478932

Runx1/AML1 in normal and abnormal hematopoiesis.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3478932

A unique clonal JAK2 mutation leading to constitutive signalling causes polycythaemia vera

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3478932

Gata2 specifies serotonergic neurons downstream of sonic hedgehog

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3478932

Biology, clinical, and hematologic features of acute megakaryoblastic leukemia in children

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3478932

The ETO (MTG8) gene family

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3478932

Acquired mutations in GATA1 in the megakaryoblastic leukemia of Down syndrome

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3478932

Recurrence of OTT-MAL fusion in t(1;22) of infant AML-M7.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3478932

Fusion of two novel genes, RBM15 and MKL1, in the t(1;22)(p13;q13) of acute megakaryoblastic leukemia.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3478932

Involvement of a human gene related to the Drosophila spen gene in the recurrent t(1;22) translocation of acute megakaryocytic leukemia

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3478932

Establishment and characterization of a megakaryoblast cell line with amplification of MLL.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3478932

JAK2 mutation 1849G>T is rare in acute leukemias but can be found in CMML, Philadelphia chromosome-negative CML, and megakaryocytic leukemia

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3478932

The translocation t(1;22)(p13;q13) is a nonrandom marker specifically associated with acute megakaryocytic leukemia in young children

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3478932

A novel real-time RT-PCR assay for quantification of OTT-MAL fusion transcript reliable for diagnosis of t(1;22) and minimal residual disease (MRD) detection.

29 June 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20121343

BMP4 regulation of human megakaryocytic differentiation is involved in thrombopoietin signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20121343

Transfer of differentiation signal by membrane microvesicles harboring hedgehog morphogens.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20121343

CD56 expression predicts occurrence of CNS disease in acute lymphoblastic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20121343

Acute megakaryoblastic leukemia in a child with the MLL-AF4 fusion gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20121343

Developmental stage-selective effect of somatically mutated leukemogenic transcription factor GATA1

21 January 2018

1 reference

12 December 2020

Complex karyotype defined by molecular cytogenetic FISH and M-FISH in an infant with acute megakaryoblastic leukemia and neurofibromatosis

1 reference

12 December 2020

Cytogenetic profile of childhood and adult megakaryoblastic leukemia (M7): a study of the Groupe Français de Cytogénétique Hématologique (GFCH)

1 reference

12 December 2020

A novel type of MLL/AF10 fusion transcript in a child with acute megakaryocytic leukemia (AML-M7)

1 reference

12 December 2020

Identifiers

DOI

10.1084/JEM.20121343

1 reference

13 August 2017

1 reference

13 August 2017

PubMed publication ID

23045605

1 reference