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Alternative polyadenylation: new insights from global analyses
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scholarly article
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Europe PubMed Central
PMCID
3504663
retrieved
14 August 2017
title
Alternative polyadenylation: new insights from global analyses
(English)
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stated in
Europe PubMed Central
PMCID
3504663
retrieved
14 August 2017
author name string
Yongsheng Shi
series ordinal
1
1 reference
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Europe PubMed Central
PMCID
3504663
retrieved
14 August 2017
language of work or name
English
0 references
publication date
24 October 2012
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Europe PubMed Central
PMCID
3504663
retrieved
14 August 2017
published in
RNA
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Europe PubMed Central
PMCID
3504663
retrieved
14 August 2017
volume
18
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stated in
Europe PubMed Central
PMCID
3504663
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14 August 2017
issue
12
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Europe PubMed Central
PMCID
3504663
retrieved
14 August 2017
page(s)
2105-2117
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Europe PubMed Central
PMCID
3504663
retrieved
14 August 2017
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Neuron-specific ELAV/Hu proteins suppress HuR mRNA during neuronal differentiation by alternative polyadenylation
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Transcriptional activity regulates alternative cleavage and polyadenylation
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RNA-binding protein HuR autoregulates its expression by promoting alternative polyadenylation site usage
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p38 MAPK controls prothrombin expression by regulated RNA 3' end processing
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Comprehensive polyadenylation site maps in yeast and human reveal pervasive alternative polyadenylation
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Formation, regulation and evolution of Caenorhabditis elegans 3'UTRs
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Evidence that cleavage factor Im is a heterotetrameric protein complex controlling alternative polyadenylation
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iCLIP reveals the function of hnRNP particles in splicing at individual nucleotide resolution
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Integrative modeling defines the Nova splicing-regulatory network and its combinatorial controls
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Transcriptome-wide identification of RNA-binding protein and microRNA target sites by PAR-CLIP
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30 September 2017
Molecular mechanisms of eukaryotic pre-mRNA 3' end processing regulation
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30 September 2017
Reprogramming of 3' untranslated regions of mRNAs by alternative polyadenylation in generation of pluripotent stem cells from different cell types
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30 September 2017
Transcription elongation factor ELL2 directs immunoglobulin secretion in plasma cells by stimulating altered RNA processing.
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Widespread shortening of 3'UTRs by alternative cleavage and polyadenylation activates oncogenes in cancer cells
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CTCF: master weaver of the genome
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Progressive lengthening of 3' untranslated regions of mRNAs by alternative polyadenylation during mouse embryonic development.
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30 September 2017
Execution of nonsense-mediated mRNA decay: what defines a substrate?
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30 September 2017
ESRP1 and ESRP2 are epithelial cell-type-specific regulators of FGFR2 splicing
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30 September 2017
Pre-mRNA processing reaches back to transcription and ahead to translation
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30 September 2017
An RNA code for the FOX2 splicing regulator revealed by mapping RNA-protein interactions in stem cells
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The tumor suppressor Cdc73 functionally associates with CPSF and CstF 3' mRNA processing factors
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30 September 2017
Genome-wide analysis of MEF2 transcriptional program reveals synaptic target genes and neuronal activity-dependent polyadenylation site selection
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30 September 2017
HITS-CLIP yields genome-wide insights into brain alternative RNA processing
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Alternative isoform regulation in human tissue transcriptomes
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30 September 2017
Proliferating cells express mRNAs with shortened 3' untranslated regions and fewer microRNA target sites
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30 September 2017
The transcriptional landscape of the yeast genome defined by RNA sequencing
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30 September 2017
Regulation of alternative polyadenylation by genomic imprinting
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30 September 2017
3' end mRNA processing: molecular mechanisms and implications for health and disease
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30 September 2017
Loss of polyadenylation protein tauCstF-64 causes spermatogenic defects and male infertility.
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30 September 2017
Point mutations and genomic deletions in CCND1 create stable truncated cyclin D1 mRNAs that are associated with increased proliferation rate and shorter survival
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30 September 2017
Knock-down of 25 kDa subunit of cleavage factor Im in Hela cells alters alternative polyadenylation within 3'-UTRs
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30 September 2017
Differential repression of alternative transcripts: a screen for miRNA targets
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30 September 2017
Drosophila Sex-lethal protein mediates polyadenylation switching in the female germline
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30 September 2017
Nova regulates brain-specific splicing to shape the synapse
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30 September 2017
Rules of engagement: co-transcriptional recruitment of pre-mRNA processing factors
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30 September 2017
Computational analysis of 3'-ends of ESTs shows four classes of alternative polyadenylation in human, mouse, and rat
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30 September 2017
An extensive network of coupling among gene expression machines
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3504663
retrieved
30 September 2017
Heterogeneity in polyadenylation cleavage sites in mammalian mRNA sequences: implications for SAGE analysis.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3504663
retrieved
30 September 2017
Tissue-specific autoregulation of Drosophila suppressor of forked by alternative poly(A) site utilization leads to accumulation of the suppressor of forked protein in mitotically active cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3504663
retrieved
30 September 2017
Patterns of variant polyadenylation signal usage in human genes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3504663
retrieved
30 September 2017
RNA polymerase II and the integration of nuclear events
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3504663
retrieved
30 September 2017
Two distinct forms of the 64,000 Mr protein of the cleavage stimulation factor are expressed in mouse male germ cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3504663
retrieved
30 September 2017
Formation of mRNA 3' ends in eukaryotes: mechanism, regulation, and interrelationships with other steps in mRNA synthesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3504663
retrieved
30 September 2017
Alternative polyadenylation events contribute to the induction of NF-ATc in effector T cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3504663
retrieved
30 September 2017
Regulation of poly(A) site choice of several yeast mRNAs
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3504663
retrieved
30 September 2017
Aberrant RNA processing in a neurodegenerative disease: the cause for absent EAAT2, a glutamate transporter, in amyotrophic lateral sclerosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3504663
retrieved
30 September 2017
Mechanism and regulation of mRNA polyadenylation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3504663
retrieved
30 September 2017
Alternative poly(A) site selection in complex transcription units: means to an end?
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3504663
retrieved
30 September 2017
The polyadenylation factor CstF-64 regulates alternative processing of IgM heavy chain pre-mRNA during B cell differentiation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3504663
retrieved
30 September 2017
Two mRNAs can be produced from a single immunoglobulin mu gene by alternative RNA processing pathways
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3504663
retrieved
30 September 2017
Synthesis of secreted and membrane-bound immunoglobulin mu heavy chains is directed by mRNAs that differ at their 3' ends
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3504663
retrieved
30 September 2017
Thalassemia due to a mutation in the cleavage-polyadenylation signal of the human beta-globin gene
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3504663
retrieved
30 September 2017
Structural organization of the human alpha-galactosidase A gene: further evidence for the absence of a 3' untranslated region
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3504663
retrieved
30 September 2017
Arylsulfatase A pseudodeficiency: loss of a polyadenylylation signal and N-glycosylation site
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3504663
retrieved
30 September 2017
Determinants of mRNA localization
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3504663
retrieved
30 September 2017
Genome-wide determination of a broad ESRP-regulated posttranscriptional network by high-throughput sequencing
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3504663
retrieved
28 June 2018
Molecular architecture of the human pre-mRNA 3' processing complex
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3504663
retrieved
28 June 2018
Two mRNAs with different 3' ends encode membrane-bound and secreted forms of immunoglobulin mu chain
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3504663
retrieved
28 June 2018
The sequence 5'-AAUAAA-3'forms parts of the recognition site for polyadenylation of late SV40 mRNAs.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3504663
retrieved
28 June 2018
Direct sequencing of Arabidopsis thaliana RNA reveals patterns of cleavage and polyadenylation.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3504663
retrieved
21 September 2018
Genome-wide analysis of pre-mRNA 3' end processing reveals a decisive role of human cleavage factor I in the regulation of 3' UTR length.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3504663
retrieved
21 September 2018
Mediator complex regulates alternative mRNA processing via the MED23 subunit.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3504663
retrieved
21 September 2018
The spen family protein FPA controls alternative cleavage and polyadenylation of RNA.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3504663
retrieved
21 September 2018
Targeted 3' processing of antisense transcripts triggers Arabidopsis FLC chromatin silencing.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3504663
retrieved
21 September 2018
Biased alternative polyadenylation in human tissues
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3504663
retrieved
21 September 2018
A faux 3'-UTR promotes aberrant termination and triggers nonsense-mediated mRNA decay
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3504663
retrieved
21 September 2018
Maximum entropy modeling of short sequence motifs with applications to RNA splicing signals.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3504663
retrieved
21 September 2018
FY is an RNA 3' end-processing factor that interacts with FCA to control the Arabidopsis floral transition.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3504663
retrieved
21 September 2018
Size heterogeneity in the 3' end of dihydrofolate reductase messenger RNAs in mouse cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3504663
retrieved
21 September 2018
Alpha-thalassaemia caused by a polyadenylation signal mutation.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3504663
retrieved
21 September 2018
A rare polyadenylation signal mutation of the FOXP3 gene (AAUAAA-->AAUGAA) leads to the IPEX syndrome
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/23097429
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
The human U1A snRNP protein regulates polyadenylation via a direct interaction with poly(A) polymerase
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/23097429
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1261/RNA.035899.112
1 reference
stated in
Europe PubMed Central
PMCID
3504663
retrieved
14 August 2017
Fatcat ID
release_idb4ksnsozgtdp3zizjpco2o54
1 reference
stated in
Fatcat
reference URL
https://api.fatcat.wiki/v0/release/idb4ksnsozgtdp3zizjpco2o54
retrieved
24 November 2022
based on heuristic
mapped directly with Wikidata item
PMCID
3504663
1 reference
stated in
Europe PubMed Central
PMCID
3504663
retrieved
14 August 2017
PubMed ID
23097429
1 reference
stated in
Europe PubMed Central
PMCID
3504663
retrieved
14 August 2017
ResearchGate publication ID
232700488
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