(Q36427654)

English

Antimalarial activity of artefenomel (OZ439), a novel synthetic antimalarial endoperoxide, in patients with Plasmodium falciparum and Plasmodium vivax malaria: an open-label phase 2 trial

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scholarly article

1 reference

Europe PubMed Central

14 August 2017

Antimalarial activity of artefenomel (OZ439), a novel synthetic antimalarial endoperoxide, in patients with Plasmodium falciparum and Plasmodium vivax malaria: an open-label phase 2 trial (English)

1 reference

Europe PubMed Central

14 August 2017

phase II clinical trial

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Plasmodium falciparum

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Plasmodium vivax

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Plasmodium vivax malaria

1 reference

based on heuristic

inferred from title

object named as

Aung Pyae Phyo

1

0 references

Nicholas John White

6

object named as

Nicholas J White

1 reference

Europe PubMed Central

14 August 2017

5

object named as

Mallika Imwong

1 reference

Europe PubMed Central

14 August 2017

François Nosten

3

object named as

François H Nosten

1 reference

Europe PubMed Central

14 August 2017

Sasithon Pukrittayakamee

4

object named as

Sasithon Pukrittayakamee

1 reference

Europe PubMed Central

14 August 2017

Podjanee Jittamala

2

object named as

Podjanee Jittamala

1 reference

Europe PubMed Central

14 August 2017

author name string

Stephan Duparc

7

1 reference

Europe PubMed Central

14 August 2017

Fiona Macintyre

8

1 reference

Europe PubMed Central

14 August 2017

Mark Baker

9

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Europe PubMed Central

14 August 2017

Jörg J Möhrle

10

1 reference

Europe PubMed Central

14 August 2017

language of work or name

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based on heuristic

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publication date

1 October 2015

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Europe PubMed Central

14 August 2017

Lancet Infectious Diseases

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Europe PubMed Central

14 August 2017

16

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Europe PubMed Central

14 August 2017

1

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Europe PubMed Central

14 August 2017

61-69

1 reference

Europe PubMed Central

14 August 2017

Elimination of Plasmodium falciparum in an area of multi-drug resistance

1 reference

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30 September 2017

Ferroquine and its derivatives: new generation of antimalarial agents.

1 reference

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30 September 2017

A long-duration dihydroorotate dehydrogenase inhibitor (DSM265) for prevention and treatment of malaria

1 reference

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30 September 2017

Evidence of Plasmodium falciparum Malaria Multidrug Resistance to Artemisinin and Piperaquine in Western Cambodia: Dihydroartemisinin-Piperaquine Open-Label Multicenter Clinical Assessment

1 reference

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30 September 2017

Malaria medicines: a glass half full?

1 reference

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30 September 2017

Evaluation of the QT effect of a combination of piperaquine and a novel anti-malarial drug candidate OZ439, for the treatment of uncomplicated malaria

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4700386

30 September 2017

Spread of artemisinin-resistant Plasmodium falciparum in Myanmar: a cross-sectional survey of the K13 molecular marker

1 reference

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30 September 2017

Fixed dose combination of arterolane and piperaquine: a newer prospect in antimalarial therapy

1 reference

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30 September 2017

Population Pharmacokinetics and Antimalarial Pharmacodynamics of Piperaquine in Patients With Plasmodium vivax Malaria in Thailand

1 reference

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30 September 2017

Spread of artemisinin resistance in Plasmodium falciparum malaria

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4700386

30 September 2017

Population pharmacokinetic assessment of the effect of food on piperaquine bioavailability in patients with uncomplicated malaria

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4700386

30 September 2017

A molecular marker of artemisinin-resistant Plasmodium falciparum malaria

1 reference

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30 September 2017

Therapeutic efficacy of fixed dose artesunate-mefloquine for the treatment of acute, uncomplicated Plasmodium falciparum malaria in Kampong Speu, Cambodia

1 reference

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30 September 2017

High-throughput analysis of antimalarial susceptibility data by the worldwide antimalarial resistance network (WWARN) In Vitro analysis and reporting tool

1 reference

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30 September 2017

Malaria burden and artemisinin resistance in the mobile and migrant population on the Thai-Myanmar border, 1999-2011: an observational study

1 reference

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30 September 2017

Efficacy of dihydroartemisinin-piperaquine for treatment of uncomplicated Plasmodium falciparum and Plasmodium vivax in Cambodia, 2008 to 2010.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4700386

30 September 2017

The WWARN antimalarial quality surveyor

1 reference

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30 September 2017

First-in-man safety and pharmacokinetics of synthetic ozonide OZ439 demonstrates an improved exposure profile relative to other peroxide antimalarials

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4700386

30 September 2017

Factors associated with non-adherence to Artemisinin-based combination therapy (ACT) to malaria in a rural population from holoendemic region of western Kenya

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4700386

30 September 2017

Arterolane maleate plus piperaquine phosphate for treatment of uncomplicated Plasmodium falciparum malaria: a comparative, multicenter, randomized clinical trial

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4700386

30 September 2017

Population pharmacokinetics of dihydroartemisinin and piperaquine in pregnant and nonpregnant women with uncomplicated malaria

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4700386

30 September 2017

Standardizing the measurement of parasite clearance in falciparum malaria: the parasite clearance estimator

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4700386

30 September 2017

Review of the clinical pharmacokinetics of artesunate and its active metabolite dihydroartemisinin following intravenous, intramuscular, oral or rectal administration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4700386

30 September 2017

The antimalarial ferroquine: from bench to clinic

1 reference

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30 September 2017

Drug-Resistant Malaria: The Era of ACT.

1 reference

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30 September 2017

Synthetic ozonide drug candidate OZ439 offers new hope for a single-dose cure of uncomplicated malaria

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4700386

30 September 2017

Arterolane, a new synthetic trioxolane for treatment of uncomplicated Plasmodium falciparum malaria: a phase II, multicenter, randomized, dose-finding clinical trial

1 reference

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30 September 2017

The molecular mechanism of action of artemisinin--the debate continues.

1 reference

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30 September 2017

New medicines to improve control and contribute to the eradication of malaria

1 reference

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30 September 2017

Changes in the treatment responses to artesunate-mefloquine on the northwestern border of Thailand during 13 years of continuous deployment

1 reference

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30 September 2017

Artemisinins: their growing importance in medicine

1 reference

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30 September 2017

Artemisinin-based combination treatment of falciparum malaria.

1 reference

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30 September 2017

Cardiotoxicity of antimalarial drugs

1 reference

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30 September 2017

Artemisinin-based combinations

1 reference

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30 September 2017

Identification of an antimalarial synthetic trioxolane drug development candidate

1 reference

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30 September 2017

Bradycardias and atrioventricular conduction block

1 reference

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30 September 2017

The medical dictionary for regulatory activities (MedDRA).

1 reference

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30 September 2017

Safety, tolerability and pharmacokinetic profile of single and multiple oral doses of arterolane (RBx11160) maleate in healthy subjects

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4700386

21 September 2018

Pharmacokinetics and pharmacodynamics of arterolane maleate following multiple oral doses in adult patients with P. falciparum malaria.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4700386

21 September 2018

Pharmacokinetics of dihydroartemisinin in Artekin tablets for single and repeated dosing in Chinese healthy volunteers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4700386

21 September 2018

The Fe2+-mediated decomposition, PfATP6 binding, and antimalarial activities of artemisone and other artemisinins: the unlikelihood of C-centered radicals as bioactive intermediates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4700386

21 September 2018

Efficacy of artemether-lumefantrine for the treatment of uncomplicated falciparum malaria in northwest Cambodia.

1 reference

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21 September 2018

Identifiers

10.1016/S1473-3099(15)00320-5

1 reference

Europe PubMed Central

14 August 2017

1 reference

Europe PubMed Central

14 August 2017

1 reference

Europe PubMed Central

14 August 2017

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