(Q36436446)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25344630%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

title

An α2-Na/K ATPase/α-adducin complex in astrocytes triggers non-cell autonomous neurodegeneration (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25344630%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

0 references

1 reference

4

1 reference

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21 February 2020

author name string

Gilbert Gallardo

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25344630%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

Jessica Barowski

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25344630%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

John Ravits

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25344630%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

Jerry B Lingrel

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25344630%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

Janice Robertson

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25344630%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

Hanno Steen

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25344630%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

Azad Bonni

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25344630%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

language of work or name

English

0 references

publication date

26 October 2014

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25344630%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25344630%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

volume

17

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25344630%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

issue

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25344630%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

page(s)

1710-1719

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25344630%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1038/nn.3853

21 February 2020

exact match

0 references

cites work

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30 September 2017

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Intricate interplay between astrocytes and motor neurons in ALS.

30 September 2017

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CD36 and Na/K-ATPase-α1 form a proinflammatory signaling loop in kidney

30 September 2017

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Reactive Oxygen Species Modulation of Na/K-ATPase Regulates Fibrosis and Renal Proximal Tubular Sodium Handling

30 September 2017

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Astrocytes conspire with neurons during progression of neurological disease

30 September 2017

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Alterations in intrinsic membrane properties and the axon initial segment in a mouse model of Angelman syndrome

30 September 2017

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Astrocytes from familial and sporadic ALS patients are toxic to motor neurons

30 September 2017

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Mitochondrial reactive oxygen species promote production of proinflammatory cytokines and are elevated in TNFR1-associated periodic syndrome (TRAPS)

30 September 2017

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Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome

30 September 2017

1 reference

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A role for mitochondria in NLRP3 inflammasome activation

30 September 2017

1 reference

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In vivo expression of polyglutamine-expanded huntingtin by mouse striatal astrocytes impairs glutamate transport: a correlation with Huntington's disease subjects

30 September 2017

1 reference

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Non-cell autonomous toxicity in neurodegenerative disorders: ALS and beyond

30 September 2017

1 reference

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Genetics of motor neuron disorders: new insights into pathogenic mechanisms

30 September 2017

1 reference

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Targeted deletion of alpha-adducin results in absent beta- and gamma-adducin, compensated hemolytic anemia, and lethal hydrocephalus in mice

30 September 2017

1 reference

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alpha-Adducin mutations increase Na/K pump activity in renal cells by affecting constitutive endocytosis: implications for tubular Na reabsorption

30 September 2017

1 reference

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Astrocytes as determinants of disease progression in inherited amyotrophic lateral sclerosis

30 September 2017

1 reference

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Astrocytes expressing ALS-linked mutated SOD1 release factors selectively toxic to motor neurons

30 September 2017

1 reference

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Non-cell autonomous effect of glia on motor neurons in an embryonic stem cell-based ALS model

30 September 2017

1 reference

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Deficiency in Na,K-ATPase alpha isoform genes alters spatial learning, motor activity, and anxiety in mice

30 September 2017

1 reference

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The inflammatory NADPH oxidase enzyme modulates motor neuron degeneration in amyotrophic lateral sclerosis mice

30 September 2017

1 reference

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Cardiac glycosides provide neuroprotection against ischemic stroke: discovery by a brain slice-based compound screening platform

30 September 2017

1 reference

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A conserved MST-FOXO signaling pathway mediates oxidative-stress responses and extends life span

30 September 2017

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Onset and progression in inherited ALS determined by motor neurons and microglia

30 September 2017

1 reference

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Expression of mutant huntingtin in glial cells contributes to neuronal excitotoxicity

30 September 2017

1 reference

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Alpha-synuclein cooperates with CSPalpha in preventing neurodegeneration

30 September 2017

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Signaling between glia and neurons: focus on synaptic plasticity

30 September 2017

1 reference

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Hypertension-linked mutation in the adducin alpha-subunit leads to higher AP2-mu2 phosphorylation and impaired Na+,K+-ATPase trafficking in response to GPCR signals and intracellular sodium

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4703324

Unraveling the mechanisms involved in motor neuron degeneration in ALS

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4703324

New insights into neuron-glia communication

30 September 2017

1 reference

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Biochemistry of Na,K-ATPase

30 September 2017

1 reference

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El Escorial revisited: revised criteria for the diagnosis of amyotrophic lateral sclerosis

30 September 2017

1 reference

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Adducin: structure, function and regulation

30 September 2017

1 reference

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Polymorphisms of alpha-adducin and salt sensitivity in patients with essential hypertension

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4703324

Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4703324

Motor neuron degeneration in mice that express a human Cu,Zn superoxide dismutase mutation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4703324

Selective loss of glial glutamate transporter GLT-1 in amyotrophic lateral sclerosis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4703324

Cell-specific expression of mRNAs encoding Na+,K(+)-ATPase alpha- and beta-subunit isoforms within the rat central nervous system

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4703324

Motor neuron degeneration in amyotrophic lateral sclerosis mutant superoxide dismutase-1 transgenic mice: mechanisms of mitochondriopathy and cell death.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4703324

Lentiviral-mediated silencing of SOD1 through RNA interference retards disease onset and progression in a mouse model of ALS.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4703324

A novel action of histone deacetylase inhibitors in a protein aggresome disease model.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4703324

Na,K-ATPase alpha 2 inhibition alters calcium responses in optic nerve astrocytes.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4703324

A screen for drugs that protect against the cytotoxicity of polyglutamine-expanded androgen receptor.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4703324

Wild-Type Nonneuronal Cells Extend Survival of SOD1 Mutant Motor Neurons in ALS Mice

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4703324

SCA7 knockin mice model human SCA7 and reveal gradual accumulation of mutant ataxin-7 in neurons and abnormalities in short-term plasticity.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4703324

Polyglutamine-expanded ataxin-7 promotes non-cell-autonomous purkinje cell degeneration and displays proteolytic cleavage in ataxic transgenic mice.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4703324

Inflammatory genes are upregulated in expanded ataxin-3-expressing cell lines and spinocerebellar ataxia type 3 brains

21 September 2018

1 reference

12 December 2020

RNA interference reveals a requirement for myocyte enhancer factor 2A in activity-dependent neuronal survival

1 reference

12 December 2020

Protein kinase and protein phosphatase expression in amyotrophic lateral sclerosis spinal cord

1 reference

12 December 2020

Global loss of Na,K-ATPase and its nitric oxide-mediated regulation in a transgenic mouse model of amyotrophic lateral sclerosis

1 reference

12 December 2020

Optimized protocols for isolation of primary motor neurons, astrocytes and microglia from embryonic mouse spinal cord.

1 reference

12 December 2020

Increased phospho-adducin immunoreactivity in a murine model of amyotrophic lateral sclerosis

1 reference

12 December 2020

Identifiers

DOI

10.1038/NN.3853

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25344630%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25344630%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

1 reference