(Q36498768)

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Immunology of neurological gene therapy: how T cells modulate viral vector-mediated therapeutic transgene expression through immunological synapses

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17920552%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

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Europe PubMed Central

Immunology of neurological gene therapy: how T cells modulate viral vector-mediated therapeutic transgene expression through immunological synapses (English)

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17920552%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

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Maria G. Castro

3

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17920552%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

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Pedro R Lowenstein

1

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17920552%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

Kurt Kroeger

2

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17920552%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

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1 October 2007

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17920552%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

Neurotherapeutics

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17920552%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

4

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17920552%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

4

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Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17920552%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

715-724

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17920552%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

Immunological thresholds in neurological gene therapy: highly efficient elimination of transduced cells might be related to the specific formation of immunological synapses between T cells and virus-infected brain cells.

1 reference

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1 reference

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1 reference

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The neuronal sortilin-related receptor SORL1 is genetically associated with Alzheimer disease

1 reference

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In vivo mature immunological synapses forming SMACs mediate clearance of virally infected astrocytes from the brain

1 reference

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Tuning immune responses: diversity and adaptation of the immunological synapse.

1 reference

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RET expression does not change with age in the substantia nigra pars compacta of rhesus monkeys

1 reference

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Epitope spreading initiates in the CNS in two mouse models of multiple sclerosis.

1 reference

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30 September 2017

Lentiviral vector delivery of parkin prevents dopaminergic degeneration in an alpha-synuclein rat model of Parkinson's disease

1 reference

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30 September 2017

Neuronal expression of the transcription factor Gli1 using the Talpha1 alpha-tubulin promoter is neuroprotective in an experimental model of Parkinson's disease.

1 reference

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30 September 2017

Overexpression of glial cell line-derived neurotrophic factor using a lentiviral vector induces time- and dose-dependent downregulation of tyrosine hydroxylase in the intact nigrostriatal dopamine system.

1 reference

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30 September 2017

Inflammation in the central nervous system: the role for dendritic cells

1 reference

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30 September 2017

T cell receptor signaling precedes immunological synapse formation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268648

30 September 2017

An AAV-derived Apaf-1 dominant negative inhibitor prevents MPTP toxicity as antiapoptotic gene therapy for Parkinson's disease

1 reference

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30 September 2017

Subthalamic GAD gene transfer in Parkinson disease patients who are candidates for deep brain stimulation.

1 reference

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30 September 2017

An improved helper-dependent adenoviral vector allows persistent gene expression after intramuscular delivery and overcomes preexisting immunity to adenovirus

1 reference

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Dendritic cell biology and regulation of dendritic cell trafficking by chemokines

1 reference

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30 September 2017

Toxicity associated with repeated administration of first-generation adenovirus vectors does not occur with a helper-dependent vector.

1 reference

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30 September 2017

The immunological synapse and the actin cytoskeleton: molecular hardware for T cell signaling.

1 reference

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30 September 2017

Peripheral infection with adenovirus causes unexpected long-term brain inflammation in animals injected intracranially with first-generation, but not with high-capacity, adenovirus vectors: toward realistic long-term neurological gene therapy for ch

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30 September 2017

Chronic brain inflammation and persistent herpes simplex virus 1 thymidine kinase expression in survivors of syngeneic glioma treated by adenovirus-mediated gene therapy: implications for clinical trials

1 reference

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30 September 2017

The immunological synapse: a molecular machine controlling T cell activation

1 reference

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Three-dimensional segregation of supramolecular activation clusters in T cells

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The immunogenicity of intracerebral virus infection depends on anatomical site.

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GDNF: a glial cell line-derived neurotrophic factor for midbrain dopaminergic neurons

1 reference

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The nerve growth factor 35 years later

1 reference

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The stimulatory potency of T cell antigens is influenced by the formation of the immunological synapse

1 reference

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Rapid upregulation of interferon-regulated and chemokine mRNAs upon injection of 108 international units, but not lower doses, of adenoviral vectors into the brain

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28 June 2018

NAIP protects the nigrostriatal dopamine pathway in an intrastriatal 6-OHDA rat model of Parkinson's disease.

1 reference

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1 reference

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1 reference

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1 reference

https://api.crossref.org/works/10.1016%2FJ.NURT.2007.07.010

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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T cells use two directionally distinct pathways for cytokine secretion.

1 reference

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21 September 2018

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10.1016/J.NURT.2007.07.010

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17920552%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17920552%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

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Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17920552%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

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