(Q36506869)

English

The novel, orally available and peripherally restricted selective cannabinoid CB2 receptor agonist LEI-101 prevents cisplatin-induced nephrotoxicity

scientific article published on 23 September 2015

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

The novel, orally available and peripherally restricted selective cannabinoid CB2 receptor agonist LEI-101 prevents cisplatin-induced nephrotoxicity (English)

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

0 references

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cannabinoid receptor

0 references

17

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Europe PubMed Central

PMC publication ID

14 August 2017

object named as

Resat Cinar

5

0 references

Laura H Heitman

object named as

Laura Heitman

13

0 references

Marc P Baggelaar

object named as

Marc Baggelaar

2

0 references

object named as

Thomas Hansen

10

0 references

Jenny Wilkerson

object named as

Jenny Wilkerson

8

0 references

Marjolein Soethoudt

12

object named as

Marjolein Soethoudt

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Aron H Lichtman

16

object named as

Aron Lichtman

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

author name string

Partha Mukhopadhyay

1

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Katalin Erdelyi

3

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Zongxian Cao

4

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Filomena Fezza

6

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Bogna Ignatowska-Janlowska

7

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Noortje van Gils

9

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Marc Ruben

11

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

George Kunos

14

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Mauro Maccarrone

15

1 reference

Europe PubMed Central

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14 August 2017

Mario Van der Stelt

18

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Europe PubMed Central

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14 August 2017

language of work or name

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publication date

23 September 2015

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Europe PubMed Central

PMC publication ID

14 August 2017

British Journal of Pharmacology

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Europe PubMed Central

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14 August 2017

173

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Europe PubMed Central

PMC publication ID

14 August 2017

3

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

446-458

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Overactive cannabinoid 1 receptor in podocytes drives type 2 diabetic nephropathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4728411

30 September 2017

CB2 Cannabinoid receptors as a therapeutic target-what does the future hold?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4728411

30 September 2017

Deficiency of cannabinoid receptor of type 2 worsens renal functional and structural abnormalities in streptozotocin-induced diabetic mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4728411

30 September 2017

The Concise Guide to PHARMACOLOGY 2013/14: enzymes.

1 reference

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30 September 2017

The Concise Guide to PHARMACOLOGY 2013/14: G protein-coupled receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4728411

30 September 2017

The IUPHAR/BPS Guide to PHARMACOLOGY: an expert-driven knowledgebase of drug targets and their ligands

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4728411

30 September 2017

Multiple binding sites for small-molecule antagonists at the CC chemokine receptor 2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4728411

30 September 2017

Therapeutic utility of cannabinoid receptor type 2 (CB(2)) selective agonists

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4728411

30 September 2017

In vivo characterization of the highly selective monoacylglycerol lipase inhibitor KML29: antinociceptive activity without cannabimimetic side effects.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4728411

30 September 2017

Modulating the endocannabinoid system in human health and disease--successes and failures

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4728411

30 September 2017

β-Caryophyllene ameliorates cisplatin-induced nephrotoxicity in a cannabinoid 2 receptor-dependent manner

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4728411

30 September 2017

Mitochondrial-targeted antioxidants represent a promising approach for prevention of cisplatin-induced nephropathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4728411

30 September 2017

Poly(ADP-ribose) polymerase-1 is a key mediator of cisplatin-induced kidney inflammation and injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4728411

30 September 2017

Protective role of cannabinoid receptor type 2 in a mouse model of diabetic nephropathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4728411

30 September 2017

Enzymatic formation of N-acylethanolamines from N-acylethanolamine plasmalogen through N-acylphosphatidylethanolamine-hydrolyzing phospholipase D-dependent and -independent pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4728411

30 September 2017

Is lipid signaling through cannabinoid 2 receptors part of a protective system?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4728411

30 September 2017

Inhibitor of fatty acid amide hydrolase normalizes cardiovascular function in hypertension without adverse metabolic effects

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4728411

30 September 2017

Chronic monoacylglycerol lipase blockade causes functional antagonism of the endocannabinoid system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4728411

30 September 2017

Beneficial paracrine effects of cannabinoid receptor 2 on liver injury and regeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4728411

30 September 2017

CB1 cannabinoid receptors promote oxidative/nitrosative stress, inflammation and cell death in a murine nephropathy model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4728411

30 September 2017

Cannabinoid receptor 1 blockade ameliorates albuminuria in experimental diabetic nephropathy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4728411

30 September 2017

Cannabinoid-2 receptor limits inflammation, oxidative/nitrosative stress, and cell death in nephropathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4728411

30 September 2017

Dual blockade of FAAH and MAGL identifies behavioral processes regulated by endocannabinoid crosstalk in vivo.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4728411

30 September 2017

Activation of the cannabinoid 2 receptor (CB2) protects against experimental colitis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4728411

30 September 2017

CB2 receptor activation attenuates microcirculatory dysfunction during cerebral ischemic/reperfusion injury.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4728411

30 September 2017

Cisplatin nephrotoxicity: mechanisms and renoprotective strategies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4728411

30 September 2017

Species-specific in vitro pharmacological effects of the cannabinoid receptor 2 (CB2) selective ligand AM1241 and its resolved enantiomers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4728411

30 September 2017

Cannabinoid-2 receptor mediates protection against hepatic ischemia/reperfusion injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4728411

30 September 2017

Nitric oxide and peroxynitrite in health and disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4728411

30 September 2017

Cloning of the first sn1-DAG lipases points to the spatial and temporal regulation of endocannabinoid signaling in the brain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4728411

30 September 2017

Brain monoglyceride lipase participating in endocannabinoid inactivation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4728411

30 September 2017

HU-308: a specific agonist for CB(2), a peripheral cannabinoid receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4728411

30 September 2017

Discovery and optimization of 1-(4-(pyridin-2-yl)benzyl)imidazolidine-2,4-dione derivatives as a novel class of selective cannabinoid CB2 receptor agonists

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4728411

28 June 2018

Development of an activity-based probe and in silico design reveal highly selective inhibitors for diacylglycerol lipase-α in brain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4728411

21 September 2018

Enol carbamates as inhibitors of fatty acid amide hydrolase (FAAH) endowed with high selectivity for FAAH over the other targets of the endocannabinoid system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4728411

21 September 2018

Synthesis and evaluation of homo-bivalent GnRHR ligands

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4728411

21 September 2018

Endocannabinoid signalling in innate and adaptive immunity.

1 reference

https://api.crossref.org/works/10.1111%2FBPH.13338

21 January 2018

CB2 cannabinoid receptor-mediated peripheral antinociception

1 reference

https://pubmed.ncbi.nlm.nih.gov/26398481

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cannabinoid CB2 receptors protect against alcoholic liver disease by regulating Kupffer cell polarization in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/26398481

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1111/BPH.13338

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

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