(Q36588392)

15 August 2017

1 reference

title

Humanin and colivelin: neuronal-death-suppressing peptides for Alzheimer's disease and amyotrophic lateral sclerosis (English)

1 reference

amyotrophic lateral sclerosis

15 August 2017

0 references

0 references

1

Masaaki Matsuoka

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6494132&resulttype=core&format=json

14 May 2020

author name string

Yuichi Hashimoto

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6494132&resulttype=core&format=json

14 May 2020

Sadakazu Aiso

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6494132&resulttype=core&format=json

14 May 2020

Ikuo Nishimoto

series ordinal

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6494132&resulttype=core&format=json

14 May 2020

publication date

1 January 2006

1 reference

16958985

CNS Neuroscience & Therapeutics

15 August 2017

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6494132&resulttype=core&format=json

14 May 2020

volume

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6494132&resulttype=core&format=json

14 May 2020

issue

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6494132&resulttype=core&format=json

14 May 2020

page(s)

113-122

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6494132&resulttype=core&format=json

Unraveling the mechanisms involved in motor neuron degeneration in ALS

14 May 2020

cites work

1 reference

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Neuroprotective effect of activity-dependent neurotrophic factor against toxicity from familial amyotrophic lateral sclerosis-linked mutant SOD1 in vitro and in vivo.

21 January 2018

1 reference

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Development of a femtomolar-acting humanin derivative named colivelin by attaching activity-dependent neurotrophic factor to its N terminus: characterization of colivelin-mediated neuroprotection against Alzheimer's disease-relevant insults in vitro

21 January 2018

1 reference

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From Charcot to Lou Gehrig: deciphering selective motor neuron death in ALS

21 January 2018

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Characterization of human presenilin 1 transgenic rats: increased sensitivity to apoptosis in primary neuronal cultures.

21 January 2018

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Involvement of cell cycle elements, cyclin-dependent kinases, pRb, and E2F x DP, in B-amyloid-induced neuronal death

21 January 2018

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Increased vulnerability of hippocampal neurons to excitotoxic necrosis in presenilin-1 mutant knock-in mice.

21 January 2018

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Humanin peptide suppresses apoptosis by interfering with Bax activation

21 January 2018

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A gene encoding a putative GTPase regulator is mutated in familial amyotrophic lateral sclerosis 2

21 January 2018

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N-Formylated humanin activates both formyl peptide receptor-like 1 and 2

21 January 2018

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The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics

21 January 2018

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Multiple mechanisms underlie neurotoxicity by different types of Alzheimer's disease mutations of amyloid precursor protein.

21 January 2018

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A rescue factor abolishing neuronal cell death by a wide spectrum of familial Alzheimer's disease genes and Aβ

21 January 2018

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Molecular characterization of neurohybrid cell death induced by Alzheimer's amyloid-beta peptides via p75NTR/PLAIDD.

21 January 2018

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Involvement of tyrosine kinases and STAT3 in Humanin-mediated neuroprotection

21 January 2018

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Transforming growth factor beta2 is a neuronal death-inducing ligand for amyloid-beta precursor protein

21 January 2018

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Transforming growth factor beta2 autocrinally mediates neuronal cell death induced by amyloid-beta.

21 January 2018

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A Rac1/phosphatidylinositol 3-kinase/Akt3 anti-apoptotic pathway, triggered by AlsinLF, the product of the ALS2 gene, antagonizes Cu/Zn-superoxide dismutase (SOD1) mutant-induced motoneuronal cell death

21 January 2018

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Alsin, the product of ALS2 gene, suppresses SOD1 mutant neurotoxicity through RhoGEF domain by interacting with SOD1 mutants

21 January 2018

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Retrograde viral delivery of IGF-1 prolongs survival in a mouse ALS model.

21 January 2018

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Molecular mechanisms for neuronal cell death by Alzheimer's amyloid precursor protein-relevant insults

21 January 2018

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Effect of humanin analogues on experimentally induced impairment of spatial memory in rats

21 January 2018

1 reference

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Acetylcholinesterase and its inhibition in Alzheimer disease

21 January 2018

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Apoptosis is induced by beta-amyloid in cultured central nervous system neurons

21 January 2018

1 reference

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[Gly(14)]-Humanin improved the learning and memory impairment induced by scopolamine in vivo

21 January 2018

1 reference

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Characterization of V642I-AbetaPP-induced cytotoxicity in primary neurons

21 January 2018

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Humanin: after the discovery.

21 January 2018

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Unravelling the role of Humanin

21 January 2018

1 reference

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Humanin rescues cortical neurons from prion-peptide-induced apoptosis

21 January 2018

1 reference

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Treatment of motoneuron degeneration by intracerebroventricular delivery of VEGF in a rat model of ALS.

21 January 2018

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Secreted Abeta does not mediate neurotoxicity by antibody-stimulated amyloid precursor protein

21 January 2018

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A humanin derivative, S14G-HN, prevents amyloid-beta-induced memory impairment in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2006.00113.X

Two serine residues distinctly regulate the rescue function of Humanin, an inhibiting factor of Alzheimer's disease-related neurotoxicity: functional potentiation by isomerization and dimerization.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2006.00113.X

Characterization of the toxic mechanism triggered by Alzheimer's amyloid-beta peptides via p75 neurotrophin receptor in neuronal hybrid cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2006.00113.X

Participation of presenilin 2 in apoptosis: enhanced basal activity conferred by an Alzheimer mutation

21 January 2018

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Identification of essential amino acids in Humanin, a neuroprotective factor against Alzheimer's disease-relevant insults

21 January 2018

1 reference

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The gene encoding alsin, a protein with three guanine-nucleotide exchange factor domains, is mutated in a form of recessive amyotrophic lateral sclerosis

21 January 2018

1 reference

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Humanin, a newly identified neuroprotective factor, uses the G protein-coupled formylpeptide receptor-like-1 as a functional receptor

21 January 2018

1 reference

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Death of PC12 cells and hippocampal neurons induced by adenoviral-mediated FAD human amyloid precursor protein gene expression.

21 January 2018

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12 December 2020

Mutant presenilin-1 induces apoptosis and downregulates Akt/PKB.

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12 December 2020

Humanin inhibits cell death of serum-deprived PC12h cells

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12 December 2020

A novel rat gene encoding a Humanin-like peptide endowed with broad neuroprotective activity

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12 December 2020

VEGF: multitasking in ALS

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12 December 2020

Cytoprotective peptide humanin binds and inhibits proapoptotic Bcl-2/Bax family protein BimEL

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12 December 2020

Colivelin prolongs survival of an ALS model mouse

1 reference

12 December 2020

Neurotoxicity of a fragment of the amyloid precursor associated with Alzheimer's disease

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12 December 2020

Suppression of Mitochondrial Succinate Dehydrogenase, a Primary Target of β‐Amyloid, and Its Derivative Racemized at Ser Residue

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12 December 2020

Apoptotic cell death induced by beta-amyloid 1-42 peptide is cell type dependent

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12 December 2020

Expression of V642 APP mutant causes cellular apoptosis as Alzheimer trait-linked phenotype

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12 December 2020

A femtomolar-acting neuroprotective peptide

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12 December 2020

G protein-mediated neuronal DNA fragmentation induced by familial Alzheimer's disease-associated mutants of APP.

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12 December 2020

Expression of mutant amyloid precursor proteins induces apoptosis in PC12 cells.

1 reference

12 December 2020

Beta-amyloid neurotoxicity in vitro: evidence of oxidative stress but not protection by antioxidants

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12 December 2020

Degeneration in vivo of rat hippocampal neurons by wild-type Alzheimer amyloid precursor protein overexpressed by adenovirus-mediated gene transfer.

1 reference

12 December 2020

10.1111/J.1527-3458.2006.00113.X

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6494132&resulttype=core&format=json

14 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6494132&resulttype=core&format=json

14 May 2020

16958985

1 reference