(Q36594558)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25917367%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

title

p75NTR ectodomain is a physiological neuroprotective molecule against amyloid-beta toxicity in the brain of Alzheimer's disease (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25917367%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

0 references

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25917367%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

author name string

X-Q Yao

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25917367%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

S-S Jiao

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25917367%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

K Saadipour

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25917367%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

F Zeng

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25917367%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

Q-H Wang

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25917367%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

C Zhu

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25917367%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

L-L Shen

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25917367%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

G-H Zeng

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25917367%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

C-R Liang

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25917367%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

Y-H Liu

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25917367%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

H-Y Hou

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25917367%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

X Xu

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25917367%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

Y-P Su

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25917367%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

X-T Fan

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25917367%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

H-L Xiao

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25917367%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

L-F Lue

17

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25917367%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

Y-Q Zeng

18

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25917367%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

B Giunta

19

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25917367%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

J-H Zhong

20

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25917367%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

D G Walker

21

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25917367%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

H-D Zhou

22

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25917367%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

J Tan

23

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25917367%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

X-F Zhou

24

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25917367%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

Y-J Wang

25

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25917367%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

language of work or name

English

0 references

publication date

28 April 2015

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25917367%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25917367%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

volume

20

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25917367%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

issue

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25917367%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

page(s)

1301-1310

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25917367%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International

6 March 2020

copyright license

start time

28 April 2015

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

Amyloid beta₁₋₄₂ (Aβ₄₂) up-regulates the expression of sortilin via the p75(NTR)/RhoA signaling pathway

1 reference

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9 September 2017

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ProNGF\NGF imbalance triggers learning and memory deficits, neurodegeneration and spontaneous epileptic-like discharges in transgenic mice

9 September 2017

1 reference

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Pathogenesis and disease-modifying therapy in Alzheimer's disease: the flat line of progress

9 September 2017

1 reference

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Nerve growth factor and Alzheimer's disease: new facts for an old hypothesis

9 September 2017

1 reference

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p75 neurotrophin receptor signaling in nervous system injury and degeneration: paradox and opportunity

9 September 2017

1 reference

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Roles of p75NTR in the pathogenesis of Alzheimer's disease: a novel therapeutic target

9 September 2017

1 reference

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Alzheimer's disease: clinical trials and drug development

9 September 2017

1 reference

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Dissecting the involvement of tropomyosin-related kinase A and p75 neurotrophin receptor signaling in NGF deficit-induced neurodegeneration

9 September 2017

1 reference

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Safety and tolerability of putaminal AADC gene therapy for Parkinson disease

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4759103

Cleavage of p75 neurotrophin receptor by alpha-secretase and gamma-secretase requires specific receptor domains

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4759103

Pro-NGF isolated from the human brain affected by Alzheimer's disease induces neuronal apoptosis mediated by p75NTR.

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4759103

Sortilin is essential for proNGF-induced neuronal cell death

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4759103

P75 interacts with the Nogo receptor as a co-receptor for Nogo, MAG and OMgp

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4759103

The neurotrophin receptor p75(NTR): novel functions and implications for diseases of the nervous system

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4759103

Amyloid beta binds trimers as well as monomers of the 75-kDa neurotrophin receptor and activates receptor signaling

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4759103

Clearing the brain's amyloid cobwebs

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4759103

Binding of beta-amyloid to the p75 neurotrophin receptor induces apoptosis. A possible mechanism for Alzheimer's disease.

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4759103

Cortical neurons express nerve growth factor receptors in advanced age and Alzheimer disease

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4759103

Nuclear factor-κB regulates βAPP and β- and γ-secretases differently at physiological and supraphysiological Aβ concentrations

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4759103

Involvement of insulin-like growth factor 1 receptor signaling in the amyloid-β peptide oligomers-induced p75 neurotrophin receptor protein expression in mouse hippocampus

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4759103

Hippocampal membrane-associated p75NTR levels are increased in Alzheimer's disease

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4759103

Amyloid-β₄₂ activates the expression of BACE1 through the JNK pathway

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4759103

NFkappaB-dependent control of BACE1 promoter transactivation by Abeta42.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4759103

Oligomeric amyloid decreases basal levels of brain-derived neurotrophic factor (BDNF) mRNA via specific downregulation of BDNF transcripts IV and V in differentiated human neuroblastoma cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4759103

Mechanisms of neurotrophin receptor signalling.

30 September 2017

1 reference

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A TrkA-to-p75NTR molecular switch activates amyloid beta-peptide generation during aging

30 September 2017

1 reference

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p75 and Trk: a two-receptor system

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4759103

p75NTR regulates Abeta deposition by increasing Abeta production but inhibiting Abeta aggregation with its extracellular domain.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4759103

Effects of proNGF on neuronal viability, neurite growth and amyloid-beta metabolism

28 June 2018

1 reference

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Beta-amyloid(1-42) induces neuronal death through the p75 neurotrophin receptor.

28 June 2018

1 reference

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The precursor pro-nerve growth factor is the predominant form of nerve growth factor in brain and is increased in Alzheimer's disease

28 June 2018

1 reference

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Gene transfer and molecular cloning of the human NGF receptor.

28 June 2018

1 reference

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Localization of nerve growth factor receptors in the normal human brain and in Alzheimer's disease

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4759103

Alzheimer disease: Lessons from immunotherapy for Alzheimer disease.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4759103

PDK1 decreases TACE-mediated α-secretase activity and promotes disease progression in prion and Alzheimer's diseases

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4759103

Dendritic spine abnormalities in hippocampal CA1 pyramidal neurons underlying memory deficits in the SAMP8 mouse model of Alzheimer's disease

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4759103

Nogo-66 inhibits adhesion and migration of microglia via GTPase Rho pathway in vitro

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4759103

Trk-dependent ADAM17 activation facilitates neurotrophin survival signaling.

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4759103

Developmental axon pruning mediated by BDNF-p75NTR-dependent axon degeneration

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4759103

TrkA receptor activation by nerve growth factor induces shedding of the p75 neurotrophin receptor followed by endosomal gamma-secretase-mediated release of the p75 intracellular domain

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4759103

Precursor form of brain-derived neurotrophic factor and mature brain-derived neurotrophic factor are decreased in the pre-clinical stages of Alzheimer's disease.

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4759103

Evidence for a critical role of the tumor necrosis factor alpha convertase (TACE) in ectodomain shedding of the p75 neurotrophin receptor (p75NTR).

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4759103

Increased p75(NTR) expression in hippocampal neurons containing hyperphosphorylated tau in Alzheimer patients

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4759103

p75 neurotrophin receptor expression on adult human oligodendrocytes: signaling without cell death in response to NGF

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4759103

Grasping objects: the cortical mechanisms of visuomotor transformation

21 October 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FMP.2015.49

Induction of cell death by endogenous nerve growth factor through its p75 receptor

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FMP.2015.49

Neurotrophin receptor proteins immunoreactivity in the rat cerebellar cortex as a function of age

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25917367

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Differential expression of the p75 nerve growth factor receptor in glia and neurons of the rat dorsal root ganglia after peripheral nerve transection

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25917367

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/MP.2015.49

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25917367%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25917367%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

PubMed publication ID

25917367

1 reference