(Q36631549)

15 August 2017

1 reference

title

siRNA efficiency: structure or sequence-that is the question (English)

1 reference

15 August 2017

Jens Kurreck

1

1 reference

15 August 2017

1 January 2006

1 reference

Journal of Biomedicine and Biotechnology

15 August 2017

1 reference

15 August 2017

2006

1 reference

15 August 2017

4

1 reference

15 August 2017

83757

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Creative Commons Attribution 3.0 Unported

15 August 2017

start time

1 January 2006

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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30 September 2017

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30 September 2017

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Human RISC couples microRNA biogenesis and posttranscriptional gene silencing

30 September 2017

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Passenger-strand cleavage facilitates assembly of siRNA into Ago2-containing RNAi enzyme complexes

30 September 2017

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Argonaute2 cleaves the anti-guide strand of siRNA during RISC activation

30 September 2017

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Design of siRNAs producing unstructured guide-RNAs results in improved RNA interference efficiency.

30 September 2017

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30 September 2017

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Small RNA asymmetry in RNAi: function in RISC assembly and gene regulation.

30 September 2017

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Ribozymes, DNAzymes and small interfering RNAs as therapeutics

30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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Functional polarity is introduced by Dicer processing of short substrate RNAs

30 September 2017

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30 September 2017

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30 September 2017

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TRBP recruits the Dicer complex to Ago2 for microRNA processing and gene silencing

30 September 2017

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30 September 2017

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Local RNA target structure influences siRNA efficacy: systematic analysis of intentionally designed binding regions

30 September 2017

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Local RNA target structure influences siRNA efficacy: a systematic global analysis

30 September 2017

1 reference

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Purified Argonaute2 and an siRNA form recombinant human RISC

30 September 2017

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The prospect of silencing disease using RNA interference

30 September 2017

1 reference

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Inhibition of coxsackievirus B3 replication by small interfering RNAs requires perfect sequence match in the central region of the viral positive strand

30 September 2017

1 reference

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An endoribonuclease-prepared siRNA screen in human cells identifies genes essential for cell division

30 September 2017

1 reference

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A protein sensor for siRNA asymmetry

30 September 2017

1 reference

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siRNA therapeutics: big potential from small RNAs

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1559936

The functions of animal microRNAs

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1559936

Argonaute2 is the catalytic engine of mammalian RNAi

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1559936

Crystal structure of Argonaute and its implications for RISC slicer activity

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1559936

Sfold web server for statistical folding and rational design of nucleic acids

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1559936

The gene-silencing efficiency of siRNA is strongly dependent on the local structure of mRNA at the targeted region

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1559936

Guidelines for the selection of highly effective siRNA sequences for mammalian and chick RNA interference

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1559936

Effects on RNAi of the tight structure, sequence and position of the targeted region.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1559936

Rational siRNA design for RNA interference

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1559936

Functional siRNAs and miRNAs Exhibit Strand Bias

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1559936

Asymmetry in the assembly of the RNAi enzyme complex

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1559936

The activity of siRNA in mammalian cells is related to structural target accessibility: a comparison with antisense oligonucleotides

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1559936

Comparison of different antisense strategies in mammalian cells using locked nucleic acids, 2'-O-methyl RNA, phosphorothioates and small interfering RNA.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1559936

RNA interference blocks gene expression and RNA synthesis from hepatitis C replicons propagated in human liver cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1559936

Analysis of gene function in somatic mammalian cells using small interfering RNAs

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1559936

Positional effects of short interfering RNAs targeting the human coagulation trigger Tissue Factor

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1559936

Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1559936

Comparison of antisense oligonucleotides and siRNAs in cell culture and in vivo.

30 September 2017

1 reference

https://api.crossref.org/works/10.1155%2FJBB%2F2006%2F83757

An algorithm for selection of functional siRNA sequences.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2FJBB%2F2006%2F83757

Improved and automated prediction of effective siRNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2FJBB%2F2006%2F83757

Efficient reduction of target RNAs by small interfering RNA and RNase H-dependent antisense agents. A comparative analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2FJBB%2F2006%2F83757

Small interfering RNA molecules as potential anti-human rhinovirus agents: in vitro potency, specificity, and mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2FJBB%2F2006%2F83757

Synthetic dsRNA Dicer substrates enhance RNAi potency and efficacy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2FJBB%2F2006%2F83757

Synthetic shRNAs as potent RNAi triggers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2FJBB%2F2006%2F83757

Developing an effective RNA interference strategy against a plus-strand RNA virus: silencing of coxsackievirus B3 and its cognate coxsackievirus-adenovirus receptor

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1559936

Comparison of the Suppressive Effects of Antisense Oligonucleotides and siRNAs Directed Against the Same Targets in Mammalian Cells

20 September 2018

1 reference

https://api.crossref.org/works/10.1155%2FJBB%2F2006%2F83757

Target accessibility dictates the potency of human RISC

21 January 2018

1 reference

12 December 2020

Antisense that comes naturally

1 reference

12 December 2020

The efficacy of small interfering RNAs targeted to the type 1 insulin-like growth factor receptor (IGF1R) is influenced by secondary structure in the IGF1R transcript

1 reference

12 December 2020

Maintaining inhibition: siRNA double expression vectors against coxsackieviral RNAs

1 reference

12 December 2020

Identifiers

DOI

10.1155/JBB/2006/83757

1 reference

15 August 2017

1 reference

PMC publication ID

1559936

15 August 2017

PubMed publication ID

17057371

1 reference

PMC publication ID

1559936