Home
Random
Nearby
Log in
Settings
Donate
About Wikidata
Disclaimers
Search
(Q36648643)
Watch
English
Unusual regioselectivity and active site topology of human cytochrome P450 2J2
scientific article published on 17 August 2007
In more languages
edit
Statements
instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PMC publication ID
2377029
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17705402%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 January 2020
title
Unusual regioselectivity and active site topology of human cytochrome P450 2J2
(English)
1 reference
stated in
Europe PubMed Central
PMC publication ID
2377029
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17705402%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 January 2020
author
Pierre Lafite
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMC publication ID
2377029
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17705402%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 January 2020
Darryl C Zeldin
series ordinal
3
1 reference
stated in
Europe PubMed Central
PMC publication ID
2377029
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17705402%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 January 2020
Patrick Dansette
series ordinal
4
1 reference
stated in
Europe PubMed Central
PMC publication ID
2377029
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17705402%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 January 2020
author name string
François André
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMC publication ID
2377029
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17705402%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 January 2020
Daniel Mansuy
series ordinal
5
1 reference
stated in
Europe PubMed Central
PMC publication ID
2377029
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17705402%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 January 2020
language of work or name
English
0 references
publication date
17 August 2007
1 reference
stated in
Europe PubMed Central
PMC publication ID
2377029
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17705402%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 January 2020
published in
Biochemistry
1 reference
stated in
Europe PubMed Central
PMC publication ID
2377029
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17705402%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 January 2020
volume
46
1 reference
stated in
Europe PubMed Central
PMC publication ID
2377029
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17705402%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 January 2020
issue
36
1 reference
stated in
Europe PubMed Central
PMC publication ID
2377029
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17705402%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 January 2020
page(s)
10237-10247
1 reference
stated in
Europe PubMed Central
PMC publication ID
2377029
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17705402%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 January 2020
cites work
Selective, competitive and mechanism-based inhibitors of human cytochrome P450 2J2.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2377029
retrieved
30 September 2017
CYP2E1 active site residues in substrate recognition sequence 5 identified by photoaffinity labeling and homology modeling
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2377029
retrieved
30 September 2017
Crystal structure of the human prostacyclin synthase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2377029
retrieved
30 September 2017
Action of epoxyeicosatrienoic acids on cellular function
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2377029
retrieved
30 September 2017
Structural basis for ligand promiscuity in cytochrome P450 3A4.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2377029
retrieved
30 September 2017
The ins and outs of cytochrome P450s.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2377029
retrieved
30 September 2017
Characterization of ebastine, hydroxyebastine, and carebastine metabolism by human liver microsomes and expressed cytochrome P450 enzymes: major roles for CYP2J2 and CYP3A.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2377029
retrieved
30 September 2017
Design and synthesis of selective, high-affinity inhibitors of human cytochrome P450 2J2.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2377029
retrieved
30 September 2017
Endothelium-derived epoxyeicosatrienoic acids and vascular function
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2377029
retrieved
30 September 2017
From endothelium-derived hyperpolarizing factor (EDHF) to angiogenesis: Epoxyeicosatrienoic acids (EETs) and cell signaling.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2377029
retrieved
30 September 2017
Crystal structure of human cytochrome P450 2D6
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2377029
retrieved
30 September 2017
Structural diversity of human xenobiotic-metabolizing cytochrome P450 monooxygenases
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2377029
retrieved
30 September 2017
Structures of human microsomal cytochrome P450 2A6 complexed with coumarin and methoxsalen
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2377029
retrieved
30 September 2017
Cytochrome P450 2J2 promotes the neoplastic phenotype of carcinoma cells and is up-regulated in human tumors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2377029
retrieved
30 September 2017
Cytochrome p450 in silico: an integrative modeling approach.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2377029
retrieved
30 September 2017
Structures of cytochrome P450 3A4.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2377029
retrieved
30 September 2017
Risk of coronary artery disease associated with polymorphism of the cytochrome P450 epoxygenase CYP2J2
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2377029
retrieved
30 September 2017
Enhancement of cardiac L-type Ca2+ currents in transgenic mice with cardiac-specific overexpression of CYP2J2
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2377029
retrieved
30 September 2017
Detection, delineation, measurement and display of cavities in macromolecular structures
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2377029
retrieved
30 September 2017
Crystal structures of human cytochrome P450 3A4 bound to metyrapone and progesterone
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2377029
retrieved
30 September 2017
Enhanced postischemic functional recovery in CYP2J2 transgenic hearts involves mitochondrial ATP-sensitive K+ channels and p42/p44 MAPK pathway
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2377029
retrieved
30 September 2017
The structure of human cytochrome P450 2C9 complexed with flurbiprofen at 2.0-A resolution
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2377029
retrieved
30 September 2017
Structure of human microsomal cytochrome P450 2C8. Evidence for a peripheral fatty acid binding site
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2377029
retrieved
30 September 2017
An open conformation of mammalian cytochrome P450 2B4 at 1.6-Å resolution
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2377029
retrieved
30 September 2017
Structure of mammalian cytochrome P450 2C5 complexed with diclofenac at 2.1 A resolution: evidence for an induced fit model of substrate binding
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2377029
retrieved
30 September 2017
Crystal structure of human cytochrome P450 2C9 with bound warfarin
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2377029
retrieved
30 September 2017
SWISS-MODEL: An automated protein homology-modeling server
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2377029
retrieved
30 September 2017
Structure of a substrate complex of mammalian cytochrome P450 2C5 at 2.3 A resolution: evidence for multiple substrate binding modes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2377029
retrieved
30 September 2017
Involvement of CYP2J2 on the intestinal first-pass metabolism of antihistamine drug, astemizole
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2377029
retrieved
30 September 2017
Mammalian microsomal cytochrome P450 monooxygenase: structural adaptations for membrane binding and functional diversity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2377029
retrieved
30 September 2017
Anti-inflammatory properties of cytochrome P450 epoxygenase-derived eicosanoids.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2377029
retrieved
30 September 2017
Assessing protein structures with a non-local atomic interaction energy.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2377029
retrieved
30 September 2017
CYP2J subfamily cytochrome P450s in the gastrointestinal tract: expression, localization, and potential functional significance
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2377029
retrieved
30 September 2017
CYP2J subfamily P450s in the lung: expression, localization, and potential functional significance
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2377029
retrieved
30 September 2017
Errors in protein structures
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2377029
retrieved
30 September 2017
Molecular cloning and expression of CYP2J2, a human cytochrome P450 arachidonic acid epoxygenase highly expressed in heart
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2377029
retrieved
30 September 2017
Hepatic epoxide hydrase. Structure-activity relations for substrates and inhibitors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2377029
retrieved
30 September 2017
Relationship between the inhibition constant (K1) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2377029
retrieved
30 September 2017
Structure of microsomal cytochrome P450 2B4 complexed with the antifungal drug bifonazole: insight into P450 conformational plasticity and membrane interaction.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2377029
retrieved
28 June 2018
Structure of mammalian cytochrome P450 2B4 complexed with 4-(4-chlorophenyl)imidazole at 1.9-A resolution: insight into the range of P450 conformations and the coordination of redox partner binding
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2377029
retrieved
28 June 2018
Synthetic inhibitors of cytochrome P-450 2A6: inhibitory activity, difference spectra, mechanism of inhibition, and protein cocrystallization.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2377029
retrieved
20 September 2018
Arachidonic acid epoxygenase metabolites stimulate endothelial cell growth and angiogenesis via mitogen-activated protein kinase and phosphatidylinositol 3-kinase/Akt signaling pathways
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2377029
retrieved
20 September 2018
Cytochrome P450-mediated oxidation of glucuronide derivatives: example of estradiol-17beta-glucuronide oxidation to 2-hydroxy-estradiol-17beta-glucuronide by CYP 2C8.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2377029
retrieved
20 September 2018
Use of molecular simulation for mapping conformational CYP2E1 epitopes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2377029
retrieved
20 September 2018
The structure of human microsomal cytochrome P450 3A4 determined by X-ray crystallography to 2.05-A resolution
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2377029
retrieved
20 September 2018
Sequence and structure of epoxide hydrolases: a systematic analysis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2377029
retrieved
20 September 2018
Regioselectivity of CYP2B6: homology modeling, molecular dynamics simulation, docking
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2377029
retrieved
20 September 2018
Involvement of CYP2J2 and CYP4F12 in the metabolism of ebastine in human intestinal microsomes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2377029
retrieved
20 September 2018
Overexpression of cytochrome P450 CYP2J2 protects against hypoxia-reoxygenation injury in cultured bovine aortic endothelial cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2377029
retrieved
20 September 2018
Activation of Galpha s mediates induction of tissue-type plasminogen activator gene transcription by epoxyeicosatrienoic acids
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2377029
retrieved
20 September 2018
Cardiac and vascular KATP channels in rats are activated by endogenous epoxyeicosatrienoic acids through different mechanisms
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/17705402
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Homology modeling of cytochrome P450scc and the mutations for optimal amperometric sensor
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/17705402
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1021/BI700876A
1 reference
stated in
Europe PubMed Central
PMC publication ID
2377029
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17705402%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 January 2020
Fatcat ID
release_czobwuggl5gxjnh2yz5plwstv4
1 reference
stated in
Fatcat
reference URL
https://api.fatcat.wiki/v0/release/czobwuggl5gxjnh2yz5plwstv4
retrieved
24 November 2022
based on heuristic
mapped directly with Wikidata item
PMC publication ID
2377029
1 reference
stated in
Europe PubMed Central
PMC publication ID
2377029
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17705402%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 January 2020
PubMed publication ID
17705402
1 reference
stated in
Europe PubMed Central
PMC publication ID
2377029
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17705402%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 January 2020
ResearchGate publication ID
6135200
0 references
Sitelinks
Wikipedia
(0 entries)
edit
Wikibooks
(0 entries)
edit
Wikinews
(0 entries)
edit
Wikiquote
(0 entries)
edit
Wikisource
(0 entries)
edit
Wikiversity
(0 entries)
edit
Wikivoyage
(0 entries)
edit
Wiktionary
(0 entries)
edit
Multilingual sites
(0 entries)
edit