(Q36675308)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26658966%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

title

Streptococcus thermophilus CRISPR-Cas9 Systems Enable Specific Editing of the Human Genome (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26658966%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

0 references

0 references

Streptococcus thermophilus

object named as

Streptococcus thermophilus

1 reference

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26658966%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

Thomas J. Cradick

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26658966%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

Toni Cathomen

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26658966%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

6

Virginijus Siksnys

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26658966%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

3

Giedrius Gasiunas

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26658966%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

author name string

Maximilian Müller

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26658966%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

Timothy H Davis

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26658966%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

Gang Bao

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26658966%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

Claudio Mussolino

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26658966%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

publication date

14 December 2015

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26658966%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26658966%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

volume

24

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26658966%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

issue

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26658966%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

page(s)

636-644

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26658966%20AND%20SRC:MED&resulttype=core&format=json

Proven and novel strategies for efficient editing of the human genome

2 March 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4786917

Measuring and Reducing Off-Target Activities of Programmable Nucleases Including CRISPR-Cas9

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4786917

In vivo genome editing using Staphylococcus aureus Cas9

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4786917

Comparison of T7E1 and surveyor mismatch cleavage assays to detect mutations triggered by engineered nucleases

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4786917

COSMID: A Web-based Tool for Identifying and Validating CRISPR/Cas Off-target Sites

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4786917

Genome editing. The new frontier of genome engineering with CRISPR-Cas9

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4786917

Structural basis of PAM-dependent target DNA recognition by the Cas9 endonuclease

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4786917

Direct observation of R-loop formation by single RNA-guided Cas9 and Cascade effector complexes.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4786917

Development and applications of CRISPR-Cas9 for genome engineering

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4786917

CRISPR/Cas9 systems have off-target activity with insertions or deletions between target DNA and guide RNA sequences

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4786917

TALENs facilitate targeted genome editing in human cells with high specificity and low cytotoxicity

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4786917

Dimeric CRISPR RNA-guided FokI nucleases for highly specific genome editing

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4786917

Genome-wide binding of the CRISPR endonuclease Cas9 in mammalian cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4786917

Highly efficient RNA-guided genome editing in human cells via delivery of purified Cas9 ribonucleoproteins

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4786917

Genome engineering with targetable nucleases

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4786917

TALEN-mediated gene mutagenesis in rhesus and cynomolgus monkeys

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4786917

DNA interrogation by the CRISPR RNA-guided endonuclease Cas9.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4786917

Cell-penetrating peptide-mediated delivery of TALEN proteins via bioconjugation for genome engineering

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4786917

Improving CRISPR-Cas nuclease specificity using truncated guide RNAs

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4786917

Phylogeny of Cas9 determines functional exchangeability of dual-RNA and Cas9 among orthologous type II CRISPR-Cas systems

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4786917

Orthogonal Cas9 proteins for RNA-guided gene regulation and editing

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4786917

Molecular mechanisms of CRISPR-mediated microbial immunity

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4786917

Efficient genome engineering in human pluripotent stem cells using Cas9 from Neisseria meningitidis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4786917

High-frequency off-target mutagenesis induced by CRISPR-Cas nucleases in human cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4786917

RNA-guided editing of bacterial genomes using CRISPR-Cas systems

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4786917

RNA-guided human genome engineering via Cas9

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4786917

Multiplex genome engineering using CRISPR/Cas systems

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4786917

Cas9-crRNA ribonucleoprotein complex mediates specific DNA cleavage for adaptive immunity in bacteria

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4786917

Cleavage of phage DNA by the Streptococcus thermophilus CRISPR3-Cas system

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4786917

Targeted gene knockout by direct delivery of zinc-finger nuclease proteins

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4786917

A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4786917

Structures of the RNA-guided surveillance complex from a bacterial immune system

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4786917

The Streptococcus thermophilus CRISPR/Cas system provides immunity in Escherichia coli

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4786917

A novel TALE nuclease scaffold enables high genome editing activity in combination with low toxicity.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4786917

Interference by clustered regularly interspaced short palindromic repeat (CRISPR) RNA is governed by a seed sequence

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4786917

CRISPR RNA maturation by trans-encoded small RNA and host factor RNase III

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4786917

The CRISPR/Cas bacterial immune system cleaves bacteriophage and plasmid DNA

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4786917

The mechanism of double-strand DNA break repair by the nonhomologous DNA end-joining pathway

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4786917

Enzymatic assembly of DNA molecules up to several hundred kilobases

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4786917

Short motif sequences determine the targets of the prokaryotic CRISPR defence system

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4786917

Rapid "open-source" engineering of customized zinc-finger nucleases for highly efficient gene modification

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4786917

Mechanism of eukaryotic homologous recombination

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4786917

Phage response to CRISPR-encoded resistance in Streptococcus thermophilus

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4786917

Diversity, activity, and evolution of CRISPR loci in Streptococcus thermophilus

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4786917

DNA-binding specificity is a major determinant of the activity and toxicity of zinc-finger nucleases

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4786917

CRISPR Provides Acquired Resistance Against Viruses in Prokaryotes

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4786917

Targeted gene editing by transfection of in vitro reconstituted Streptococcus thermophilus Cas9 nuclease complex

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4786917

Guide RNA functional modules direct Cas9 activity and orthogonality

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4786917

Efficient genome engineering in eukaryotes using Cas9 from Streptococcus thermophilus.

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4786917

Translating the genomic revolution - targeted genome editing in primates.

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4786917

Efficient genome modification by CRISPR-Cas9 nickase with minimal off-target effects.

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4786917

RNA guides genome engineering

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4786917

TALEN-mediated precise genome modification by homologous recombination in zebrafish.

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4786917

Knockout rats generated by embryo microinjection of TALENs.

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4786917

Custom zinc-finger nucleases for use in human cells.

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4786917

Knockout mice created by TALEN-mediated gene targeting

20 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26658966

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/MT.2015.218

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26658966%20AND%20SRC:MED&resulttype=core&format=json

release_yig6aafigzcbjmacc6k4bnbyxa

2 March 2020

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/yig6aafigzcbjmacc6k4bnbyxa

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26658966%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

1 reference