(Q36687848)

15 August 2017

1 reference

title

Neuroreplacement, growth factor, and small molecule neurotrophic approaches for treating Parkinson's disease (English)

1 reference

15 August 2017

Michael J O'Neill

1

1 reference

15 August 2017

Marcus J Messenger

2

1 reference

15 August 2017

Viktor Lakics

3

1 reference

15 August 2017

Tracey K Murray

4

1 reference

15 August 2017

Eric H Karran

5

1 reference

15 August 2017

Philip G Szekeres

6

1 reference

15 August 2017

Eric S Nisenbaum

7

1 reference

15 August 2017

Kalpana M Merchant

8

1 reference

15 August 2017

publication date

1 January 2007

1 reference

International Review of Neurobiology

15 August 2017

published in

1 reference

15 August 2017

volume

77

1 reference

15 August 2017

page(s)

179-217

1 reference

Expanding insights of mitochondrial dysfunction in Parkinson's disease.

15 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Biochemistry of Parkinson's disease 28 years later: a critical review

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Efficacy of brain-derived neurotrophic factor and neurotrophin-3 on neurochemical and behavioral deficits associated with partial nigrostriatal dopamine lesions

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Does neuronal loss in Parkinson's disease involve programmed cell death?

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Identification of intrinsic determinants of midbrain dopamine neurons

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Chronic AMPA receptor potentiator (LY451646) treatment increases cell proliferation in adult rat hippocampus

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Maturation but not survival of dopaminergic nigrostriatal neurons is affected in developing and aging BDNF-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Brain-derived neurotrophic factor is required for the establishment of the proper number of dopaminergic neurons in the substantia nigra pars compacta.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Neural subtype specification of fertilization and nuclear transfer embryonic stem cells and application in parkinsonian mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Continuing trials of GDNF in Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Excitotoxicity and nitric oxide in Parkinson's disease pathogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Experimental models of Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Mitochondria, Oxidative Damage, and Inflammation in Parkinson's Disease

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

trkB messenger RNA expression in normal human brain and in the substantia nigra of parkinsonian patients: an in situ hybridization study

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Chronic systemic pesticide exposure reproduces features of Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Intersecting pathways to neurodegeneration in Parkinson's disease: effects of the pesticide rotenone on DJ-1, alpha-synuclein, and the ubiquitin-proteasome system

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Experimental models of Parkinson's disease: from the static to the dynamic

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Intrastriatal injection of an adenoviral vector expressing glial-cell-line-derived neurotrophic factor prevents dopaminergic neuron degeneration and behavioral impairment in a rat model of Parkinson disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Towards a neuroprotective gene therapy for Parkinson's disease: use of adenovirus, AAV and lentivirus vectors for gene transfer of GDNF to the nigrostriatal system in the rat Parkinson model

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Neuroimaging in Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Assessment of neuroimaging techniques as biomarkers of the progression of Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Bilateral caudate and putamen grafts of embryonic mesencephalic tissue treated with lazaroids in Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Programmed cell death: does it play a role in Parkinson's disease?

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Generation of tyrosine hydroxylase positive neurons from human embryonic stem cells after coculture with cellular substrates and exposure to GDNF.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Depletion of glial cell line-derived neurotrophic factor in substantia nigra neurons of Parkinson's disease brain

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Dopaminergic neurons protected from degeneration by GDNF gene therapy

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Nurr1 in Parkinson's disease and related disorders

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Genetic engineering of mouse embryonic stem cells by Nurr1 enhances differentiation and maturation into dopaminergic neurons.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

The rise and fall of tolcapone

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Behavioural and immunohistochemical changes following supranigral administration of sonic hedgehog in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated common marmosets.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Sonic hedgehog delivered by an adeno-associated virus protects dopaminergic neurones against 6-OHDA toxicity in the rat.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Molecular Pathways of Neurodegeneration in Parkinson's Disease

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Blastula-stage stem cells can differentiate into dopaminergic and serotonergic neurons after transplantation.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Prospects for new restorative and neuroprotective treatments in Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Evaluation of animal models of Parkinson's disease for neuroprotective strategies

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

1 reference

7 January 2021

Does levodopa slow or hasten the rate of progression of Parkinson's disease?

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Levodopa and the progression of Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Genetics of Parkinson disease: paradigm shifts and future prospects.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Genetic mouse models of parkinsonism: strengths and limitations

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Parkinson-like syndrome induced by continuous MPTP infusion: convergent roles of the ubiquitin-proteasome system and alpha-synuclein

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Neuroprotective effects of GDNF against 6-OHDA in young and aged rats

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Small-molecule modulators of Hedgehog signaling: identification and characterization of Smoothened agonists and antagonists

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Transplantation of embryonic dopamine neurons for severe Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Implanted fibroblasts genetically engineered to produce brain-derived neurotrophic factor prevent 1-methyl-4-phenylpyridinium toxicity to dopaminergic neurons in the rat.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Cell-mediated delivery of brain-derived neurotrophic factor enhances dopamine levels in an MPP+ rat model of substantia nigra degeneration.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Functional recovery in parkinsonian monkeys treated with GDNF

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Direct brain infusion of glial cell line-derived neurotrophic factor in Parkinson disease

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

The Parkinson disease causing LRRK2 mutation I2020T is associated with increased kinase activity

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Deprenyl in the treatment of symptom fluctuations in advanced Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Clinical traits of LRRK2-associated Parkinson's disease in Ireland: a link between familial and idiopathic PD.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Chronic, controlled GDNF infusion promotes structural and functional recovery in advanced parkinsonian monkeys

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Cell survival and clinical outcome following intrastriatal transplantation in Parkinson disease

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Sequential bilateral transplantation in Parkinson's disease: effects of the second graft.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Mechanisms controlling gene expression by nuclear calcium signals.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Genes and parkinsonism

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Long-term evaluation of bilateral fetal nigral transplantation in Parkinson disease

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

The AMPA receptor interacts with and signals through the protein tyrosine kinase Lyn

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Recent advances in Parkinson's disease therapy: use of monoamine oxidase inhibitors

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Nurr1 regulates dopamine synthesis and storage in MN9D dopamine cells

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Glial cell line-derived neurotrophic factor reverses toxin-induced injury to midbrain dopaminergic neurons in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Rat fetal ventral mesencephalon grown as solid tissue cultures: influence of culture time and BDNF treatment on dopamine neuron survival and function.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Friedrich Heinrich Lewy (1885-1950) and his work

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Glial cell line-derived neurotrophic factor exerts neurotrophic effects on dopaminergic neurons in vitro and promotes their survival and regrowth after damage by 1-methyl-4-phenylpyridinium.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Reduced BDNF mRNA Expression in the Parkinson's Disease Substantia Nigra

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Nur77 family of nuclear hormone receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Glial cell line-derived neurotrophic factor augments midbrain dopaminergic circuits in vivo.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

What has been learnt from study of dopamine receptors in Parkinson's disease?

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

BDNF is a neurotrophic factor for dopaminergic neurons of the substantia nigra.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Induction of dopaminergic neuron phenotype in the midbrain by Sonic hedgehog protein

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Cytokine production of activated microglia and decrease in neurotrophic factors of neurons in the hippocampus of Lewy body disease brains.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Pramipexole protects against MPTP toxicity in non-human primates

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Identification of a potential nurr1 response element that activates the tyrosine hydroxylase gene promoter in cultured cells

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

The role of Nurr1 in the development of dopaminergic neurons and Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Parkinson's disease, pesticides and mitochondrial dysfunction

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Oxidative stress and the pathogenesis of Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Understanding cell death in Parkinson's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Pluripotency of mesenchymal stem cells derived from adult marrow

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

The controlled differentiation of human neural stem cells into TH-immunoreactive (ir) neurons in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Low dose pramipexole is neuroprotective in the MPTP mouse model of Parkinson's disease, and downregulates the dopamine transporter via the D3 receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Generation of dopaminergic neurons and pigmented epithelia from primate ES cells by stromal cell-derived inducing activity.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

GDNF protects nigral dopamine neurons against 6-hydroxydopamine in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

GDNF protection against 6-OHDA: time dependence and requirement for protein synthesis.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Stromal cell-derived inducing activity, Nurr1, and signaling molecules synergistically induce dopaminergic neurons from mouse embryonic stem cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Dopamine neurons derived from embryonic stem cells function in an animal model of Parkinson's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

NGF, BDNF and NT-5, but not NT-3 protect against MPP+ toxicity and oxidative stress in neonatal animals.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Elevated glial brain-derived neurotrophic factor in Parkinson's diseased nigra

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

BDNF is induced by wild-type alpha-synuclein but not by the two mutants, A30P or A53T, in glioma cell line

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

In vivo gene delivery of glial cell line--derived neurotrophic factor for Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Clinicopathological findings following intraventricular glial-derived neurotrophic factor treatment in a patient with Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Neurodegeneration prevented by lentiviral vector delivery of GDNF in primate models of Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Expectations and challenges in the therapeutic use of neurotrophic factors

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Lewy Body Pathology in Alzheimer's Disease

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Parkinson's disease. First of two parts

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Parkinson's disease. Second of two parts

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Randomized controlled trial of intraputamenal glial cell line-derived neurotrophic factor infusion in Parkinson disease

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Chronic Parkinsonism in humans due to a product of meperidine-analog synthesis

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Topographical distribution of [125I]-glial cell line-derived neurotrophic factor in unlesioned and MPTP-lesioned rhesus monkey brain following a bolus intraventricular injection

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Positive modulation of AMPA receptors increases neurotrophin expression by hippocampal and cortical neurons.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Mutations in NR4A2 associated with familial Parkinson disease

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Efficient generation of midbrain and hindbrain neurons from mouse embryonic stem cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Regulation of BDNF expression in primary neuron culture by LY392098, a novel AMPA receptor potentiator.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Selegiline orally disintegrating tablets for the treatment of Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

The adult substantia nigra contains progenitor cells with neurogenic potential.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

GDNF: a glial cell line-derived neurotrophic factor for midbrain dopaminergic neurons

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Cell therapy in Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

The generation of dopaminergic neurons by human neural stem cells is enhanced by Bcl-XL, both in vitro and in vivo.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Small molecule approaches for promoting neurogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

An AMPA receptor potentiator modulates hippocampal expression of BDNF: an in vivo study.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

The role of alpha-synuclein in Parkinson's disease: insights from animal models

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Success and problems of long-term levodopa therapy in Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Cooperative transcription activation by Nurr1 and Pitx3 induces embryonic stem cell maturation to the midbrain dopamine neuron phenotype.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

The NR4A subfamily of nuclear receptors: new early genes regulated by growth factors in vascular cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Dopaminergic loss and inclusion body formation in alpha-synuclein mice: implications for neurodegenerative disorders

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Systemic exposure to proteasome inhibitors causes a progressive model of Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Failure of the ubiquitin-proteasome system in Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Temporal evolution of mouse striatal gene expression following MPTP injury

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Novel AMPA receptor potentiators LY392098 and LY404187: effects on recombinant human AMPA receptors in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Glial cell line-derived neurotrophic factor-levodopa interactions and reduction of side effects in parkinsonian monkeys

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Brain-derived growth factor and nerve growth factor concentrations are decreased in the substantia nigra in Parkinson's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Platelet-derived growth factor (PDGF-BB) and brain-derived neurotrophic factor (BDNF) induce striatal neurogenesis in adult rats with 6-hydroxydopamine lesions

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Molecular pathophysiology of Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Distribution and retrograde transport of trophic factors in the central nervous system: functional implications for the treatment of neurodegenerative diseases

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Brain-derived neurotrophic factor in the control human brain, and in Alzheimer's disease and Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

LY503430, a novel alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptor potentiator with functional, neuroprotective and neurotrophic effects in rodent models of Parkinson's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

GDNF is a major component of trophic activity in DA-depleted striatum for survival and neurite extension of DAergic neurons

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Etiology and pathogenesis of Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

A double-blind controlled trial of bilateral fetal nigral transplantation in Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Pharmacological approaches to disease-modifying therapies in Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

AMPA receptor potentiators for the treatment of CNS disorders

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Neurotrophic actions of the novel AMPA receptor potentiator, LY404187, in rodent models of Parkinson's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

LY503430: pharmacology, pharmacokinetics, and effects in rodent models of Parkinson's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Neurospheres modified to produce glial cell line-derived neurotrophic factor increase the survival of transplanted dopamine neurons

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Reduced expression of brain-derived neurotrophic factor protein in Parkinson's disease substantia nigra.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

In vitro and in vivo analyses of human embryonic stem cell-derived dopamine neurons

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Dopamine transporter brain imaging to assess the effects of pramipexole vs levodopa on Parkinson disease progression

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Intraputamenal infusion of glial cell line-derived neurotrophic factor in PD: a two-year outcome study.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Derivation of midbrain dopamine neurons from human embryonic stem cells

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

MANF: a new mesencephalic, astrocyte-derived neurotrophic factor with selectivity for dopaminergic neurons

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Pergolide compared with bromocriptine in Parkinson's disease: a multicenter, crossover, controlled study

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Dopamine release from nigral transplants visualized in vivo in a Parkinson's patient

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Inhibiting BDNF expression by antisense oligonucleotide infusion causes loss of nigral dopaminergic neurons

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Involvement of dopamine D(2)/D(3) receptors and BDNF in the neuroprotective effects of S32504 and pramipexole against 1-methyl-4-phenylpyridinium in terminally differentiated SH-SY5Y cells

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Reply: a new look at the pathogenesis of Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

The parkinsonian toxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP): a technical review of its utility and safety

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

LY404187: A Novel Positive Allosteric Modulator of AMPA Receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Neuroprotective properties of cultured neural progenitor cells are associated with the production of sonic hedgehog

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Rasagiline in the pharmacotherapy of Parkinson's disease--a review

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

A five-year study of the incidence of dyskinesia in patients with early Parkinson's disease who were treated with ropinirole or levodopa

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

The controlled conversion of human neural progenitor cells derived from foetal ventral mesencephalon into dopaminergic neurons in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Behavioral and neurochemical effects of wild-type and mutated human alpha-synuclein in transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Pathophysiology, pleiotrophy and paradigm shifts: genetic lessons from Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Lrrk2 and Lewy body disease

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Muscarinic binding and choline acetyltransferase activity in Parkinsonian subjects with reference to dementia.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Entacapone prolongs levodopa response in a one month double blind study in parkinsonian patients with levodopa related fluctuations

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Nurr1 enhances transcription of the human dopamine transporter gene through a novel mechanism

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Nurr1 is essential for the induction of the dopaminergic phenotype and the survival of ventral mesencephalic late dopaminergic precursor neurons

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

1 reference

7 January 2021

Neuroprotection in PD—A role for dopamine agonists?

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Science, medicine, and the future: Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Differentiation of human embryonic stem cells to dopaminergic neurons in serum-free suspension culture

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Genetic Complexity and Parkinson's Disease

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Parkinson's disease and exposure to agricultural work and pesticide chemicals

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Dopaminergic neurons in rat ventral midbrain express brain-derived neurotrophic factor and neurotrophin-3 mRNAs.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Efficacy of pramipexole, a novel dopamine agonist, as monotherapy in mild to moderate Parkinson's disease. The Pramipexole Study Group

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Crossroads in GDNF therapy for Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Enhanced in vitro midbrain dopamine neuron differentiation, dopaminergic function, neurite outgrowth, and 1-methyl-4-phenylpyridium resistance in mouse embryonic stem cells overexpressing Bcl-XL.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

BDNF attenuates the effects of intrastriatal injection of 6-hydroxydopamine

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Neurotrophic factors in Alzheimer's and Parkinson's disease brain

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Adult human hematopoietic stem cells produce neurons efficiently in the regenerating chicken embryo spinal cord

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

alpha-Synuclein locus triplication causes Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Comprehensive evaluation of common genetic variation within LRRK2 reveals evidence for association with sporadic Parkinson's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Multiple small doses of levodopa plus entacapone produce continuous dopaminergic stimulation and reduce dyskinesia induction in MPTP-treated drug-naive primates

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Temporally induced Nurr1 can induce a non-neuronal dopaminergic cell type in embryonic stem cell differentiation

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Brain-Derived Neurotrophic Factor Protects Dopaminergic Cells from 6-Hydroxydopamine Toxicity

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Brain-derived neurotrophic factor protects dopamine neurons against 6-hydroxydopamine and N-methyl-4-phenylpyridinium ion toxicity: involvement of the glutathione system.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Comparison of the capability of GDNF, BDNF, or both, to protect nigrostriatal neurons in a rat model of Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Chronic neurochemical and behavioral changes in MPTP-lesioned C57BL/6 mice: a model for Parkinson's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Dopaminergic neurons generated from monkey embryonic stem cells function in a Parkinson primate model.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Ca2+ influx regulates BDNF transcription by a CREB family transcription factor-dependent mechanism

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

In situ detection of apoptotic nuclei in the substantia nigra compacta of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated mice using terminal deoxynucleotidyl transferase labelling and acridine orange staining

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

The effect of deprenyl (selegiline) on the natural history of Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Parallel induction of the formation of dopamine and its metabolites with induction of tyrosine hydroxylase expression in foetal rat and human cerebral cortical cells by brain-derived neurotrophic factor and glial-cell derived neurotrophic factor.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

A Fas-based suicide switch in human T cells for the treatment of graft-versus-host disease

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Embryonic stem cell lines derived from human blastocysts

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

LRRK2 mutations and Parkinsonism

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Protection and repair of the nigrostriatal dopaminergic system by GDNF in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Intrastriatal injection of sonic hedgehog reduces behavioral impairment in a rat model of Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Effects of Brain-derived Neurotrophic Factor on 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced Parkinsonism in Monkeys

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Pharmacologic profile of ropinirole: a nonergoline dopamine agonist

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Potentiation of responses to AMPA on central neurones by LY392098 and LY404187 in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Brain-derived neurotrophic factor prevents the loss of nigral neurons induced by excitotoxic striatal-pallidal lesions.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Orphan nuclear receptor Nurr1 is essential for Ret expression in midbrain dopamine neurons and in the brain stem

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Nurr1-RXR heterodimers mediate RXR ligand-induced signaling in neuronal cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Forskolin cooperating with growth factor on generation of dopaminergic neurons from human fetal mesencephalic neural progenitor cells

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Parkinson's disease-associated mutations in leucine-rich repeat kinase 2 augment kinase activity

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Slower progression of Parkinson's disease with ropinirole versus levodopa: The REAL-PET study

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

AMPA protects cultured neurons against glutamate excitotoxicity through a phosphatidylinositol 3-kinase-dependent activation in extracellular signal-regulated kinase to upregulate BDNF gene expression

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Possibility for neurogenesis in substantia nigra of parkinsonian brain

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Neuropharmacological, neuroprotective and amyloid precursor processing properties of selective MAO-B inhibitor antiparkinsonian drug, rasagiline

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Regulation of brain-derived neurotrophic factor and nerve growth factor mRNA in primary cultures of hippocampal neurons and astrocytes.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Dopaminergic differentiation of human embryonic stem cells

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Dopamine neuron agenesis in Nurr1-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Human bone marrow stem cells exhibit neural phenotypes and ameliorate neurological deficits after grafting into the ischemic brain of rats.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Evidence for neurogenesis in the adult mammalian substantia nigra

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Induction of tyrosine hydroxylase gene expression in human foetal cerebral cortex.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

The role of G196A polymorphism in the brain-derived neurotrophic factor gene in the cause of Parkinson's disease: a meta-analysis

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

Sustained delivery of GDNF: towards a treatment for Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

7 January 2021

https://api.crossref.org/works/10.1016%2FS0074-7742%2806%2977006-4

1 reference

7 January 2021

10.1016/S0074-7742(06)77006-4

Identifiers

DOI

1 reference

15 August 2017

1 reference