(Q36708311)

15 August 2017

1 reference

title

Potential use of IL-2/anti-IL-2 antibody immune complexes for the treatment of cancer and autoimmune disease (English)

1 reference

15 August 2017

1 reference

1 reference

1

Onur Boyman

1 reference

15 August 2017

3

Jonathan Sprent

1 reference

15 August 2017

2

Charles D Surh

1 reference

15 August 2017

language of work or name

English

0 references

publication date

1 December 2006

1 reference

Expert Opinion on Biological Therapy

15 August 2017

published in

1 reference

15 August 2017

volume

6

1 reference

15 August 2017

issue

12

1 reference

15 August 2017

page(s)

1323-1331

1 reference

Cytokines and immunodeficiency diseases: critical roles of the gamma(c)-dependent cytokines interleukins 2, 4, 7, 9, 15, and 21, and their signaling pathways

15 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1517%2F14712598.6.12.1323

Lymphokines and the immune response: the central role of interleukin-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.6.12.1323

Lymphocyte responses and cytokines

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.6.12.1323

Homeostatic maintenance of natural Foxp3(+) CD25(+) CD4(+) regulatory T cells by interleukin (IL)-2 and induction of autoimmune disease by IL-2 neutralization

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.6.12.1323

The regulatory role of dendritic cells in the immune response.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.6.12.1323

The IL-2 receptor complex: its structure, function, and target genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.6.12.1323

Selective in Vitro Growth of T Lymphocytes from Normal Human Bone Marrows

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.6.12.1323

Interleukin-2: inception, impact, and implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.6.12.1323

Ulcerative colitis-like disease in mice with a disrupted interleukin-2 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.6.12.1323

Interleukin-2 receptor α chain regulates the size and content of the peripheral lymphoid compartment

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.6.12.1323

Control of T-cell activation by CD4+ CD25+ suppressor T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.6.12.1323

Tolerance, not immunity, crucially depends on IL-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.6.12.1323

A function for interleukin 2 in Foxp3-expressing regulatory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.6.12.1323

Interleukin-2-dependent mechanisms of tolerance and immunity in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.6.12.1323

Essential role for IL-2 in the regulation of antiviral extralymphoid CD8 T cell responses.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.6.12.1323

Interleukin-2 signals during priming are required for secondary expansion of CD8+ memory T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.6.12.1323

CD4+CD25+ T regulatory cells, immunotherapy of cancer, and interleukin-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.6.12.1323

Selective stimulation of T cell subsets with antibody-cytokine immune complexes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.6.12.1323

Interleukin-2 administration causes reversible hemodynamic changes and left ventricular dysfunction similar to those seen in septic shock.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.6.12.1323

Guidelines for the safe administration of high-dose interleukin-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.6.12.1323

Interleukin-2 induces increased platelet-endothelium interactions: a potential mechanism of toxicity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.6.12.1323

Application of IL-2 and other cytokines in renal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.6.12.1323

Randomized study of high-dose and low-dose interleukin-2 in patients with metastatic renal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.6.12.1323

Toxicity and therapeutic efficacy of high-dose interleukin 2. In vivo infusion of antibody to NK-1.1 attenuates toxicity without compromising efficacy against murine leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.6.12.1323

NK cells and polymorphonuclear neutrophils are both critical for IL-2-induced pulmonary vascular leak syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.6.12.1323

Passive immunization against tumor necrosis factor partially abrogates interleukin 2 toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.6.12.1323

Pentoxifylline inhibits interleukin-2-induced toxicity in C57BL/6 mice but preserves antitumor efficacy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.6.12.1323

Evidence for a structural motif in toxins and interleukin-2 that may be responsible for binding to endothelial cells and initiating vascular leak syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.6.12.1323

Interleukin-2 programs mouse alpha beta T lymphocytes for apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.6.12.1323

Homeostasis and self-tolerance in the immune system: turning lymphocytes off.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.6.12.1323

CD8+ T cell immunity against a tumor/self-antigen is augmented by CD4+ T helper cells and hindered by naturally occurring T regulatory cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.6.12.1323

IL-2 and autoimmune disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.6.12.1323

Biochemical mechanisms of IL-2-regulated Fas-mediated T cell apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.6.12.1323

IL-2 administration increases CD4+ CD25(hi) Foxp3+ regulatory T cells in cancer patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.6.12.1323

Tumor-specific human CD4+ regulatory T cells and their ligands: implications for immunotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.6.12.1323

The IL-2/IL-15 receptor systems: targets for immunotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.6.12.1323

Cancer regression and autoimmunity in patients after clonal repopulation with antitumor lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.6.12.1323

Effect of albumin fusion on the biodistribution of interleukin-2

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.6.12.1323

Antibody-targeted interleukin 2 stimulates T-cell killing of autologous tumor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.6.12.1323

Generation of low-toxicity interleukin-2 fusion proteins devoid of vasopermeability activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.6.12.1323

Distinct biological activities of recombinant forms of human interleukin-2 in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.6.12.1323

A nonpeptidyl mimic of superoxide dismutase, M40403, inhibits dose-limiting hypotension associated with interleukin-2 and increases its antitumor effects

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.6.12.1323

Histamine improves survival and protects against interleukin-2-induced pulmonary vascular leak syndrome in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.6.12.1323

Fusokine interleukin-2/interleukin-18, a novel potent innate and adaptive immune stimulator with decreased toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.6.12.1323

Cytokine-binding proteins: stimulating antagonists

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.6.12.1323

IL-2 in vivo activities and antitumor efficacy enhanced by an anti-IL-2 mAb.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.6.12.1323

Control of homeostasis of CD8+ memory T cells by opposing cytokines.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.6.12.1323

21 January 2018

Interleukin-2 toxicity

1 reference

https://api.crossref.org/works/10.1517%2F14712598.6.12.1323

10.1517/14712598.6.12.1323

21 January 2018

Identifiers

DOI

1 reference

15 August 2017

1 reference