(Q36718130)

15 August 2017

1 reference

title

Tumor microenvironment in head and neck squamous cell carcinomas: predictive value and clinical relevance of hypoxic markers. A review (English)

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15 August 2017

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3

Johan Bussink

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15 August 2017

Ilse J Hoogsteen

1

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15 August 2017

Henri A M Marres

series ordinal

2

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15 August 2017

Albert J van der Kogel

series ordinal

4

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15 August 2017

Johannes H A M Kaanders

series ordinal

5

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15 August 2017

publication date

1 June 2007

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15 August 2017

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15 August 2017

volume

29

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15 August 2017

issue

6

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15 August 2017

page(s)

591-604

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The histological structure of some human lung cancers and the possible implications for radiotherapy

15 August 2017

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1 reference

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21 January 2018

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21 January 2018

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The Expression and Distribution of the Hypoxia-Inducible Factors HIF-1α and HIF-2α in Normal Human Tissues, Cancers, and Tumor-Associated Macrophages

21 January 2018

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Expression of hypoxia-inducible cell-surface transmembrane carbonic anhydrases in human cancer.

21 January 2018

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Hypoxia-inducible erythropoietin signaling in squamous dysplasia and squamous cell carcinoma of the uterine cervix and its potential role in cervical carcinogenesis and tumor progression

21 January 2018

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Tumour proliferation assessed by combined histological and flow cytometric analysis: implications for therapy in squamous cell carcinoma in the head and neck

21 January 2018

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Regulation of proliferation-survival decisions during tumor cell hypoxia

21 January 2018

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Tumor hypoxia and malignant progression.

21 January 2018

1 reference

7 January 2021

Pretreatment oxygenation predicts radiation response in advanced squamous cell carcinoma of the head and neck

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7 January 2021

Tumor hypoxia adversely affects the prognosis of carcinoma of the head and neck

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7 January 2021

Hypoxia in breast cancer: pathogenesis, characterization and biological/therapeutic implications

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7 January 2021

Oxygenation of advanced head and neck cancer: prognostic marker for the response to primary radiochemotherapy

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7 January 2021

Pretreatment anemia is correlated with the reduced effectiveness of radiation and concurrent chemotherapy in advanced head and neck cancer

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7 January 2021

Hypoxia--a key regulatory factor in tumour growth

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7 January 2021

Hypoxic gene expression and metastasis

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7 January 2021

Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumours

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7 January 2021

Repopulation of FaDu human squamous cell carcinoma during fractionated radiotherapy correlates with reoxygenation.

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7 January 2021

Five compared with six fractions per week of conventional radiotherapy of squamous-cell carcinoma of head and neck: DAHANCA 6 and 7 randomised controlled trial

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7 January 2021

Tumor hypoxia: definitions and current clinical, biologic, and molecular aspects

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7 January 2021

Treatment resistance of solid tumors: role of hypoxia and anemia

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7 January 2021

Quantification of longitudinal tissue pO2 gradients in window chamber tumours: impact on tumour hypoxia

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7 January 2021

Targeting hypoxia tolerance in cancer

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7 January 2021

Anemia is associated with decreased local control of surgically treated squamous cell carcinomas of the glottic larynx

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7 January 2021

The significance of anemia in squamous cell head and neck cancer treated with surgery and postoperative radiotherapy

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7 January 2021

Impact of hemoglobin level and use of recombinant erythropoietin on efficacy of preoperative chemoradiation therapy for squamous cell carcinoma of the oral cavity and oropharynx

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7 January 2021

Severe anemia is associated with poor tumor oxygenation in head and neck squamous cell carcinomas

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7 January 2021

Prognostic value of tumor oxygenation in 397 head and neck tumors after primary radiation therapy. An international multi-center study

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7 January 2021

Hypoxia-activated tumor pathways of angiogenesis and pH regulation independent of anemia in head-and-neck cancer

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7 January 2021

Hypoxia in head and neck cancer: how much, how important?

1 reference

7 January 2021

Clinical studies of hypoxia modification in radiotherapy

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7 January 2021

ARCON: a novel biology-based approach in radiotherapy

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7 January 2021

ARCON: experience in 215 patients with advanced head-and-neck cancer.

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7 January 2021

A randomized double-blind phase III study of nimorazole as a hypoxic radiosensitizer of primary radiotherapy in supraglottic larynx and pharynx carcinoma. Results of the Danish Head and Neck Cancer Study (DAHANCA) Protocol 5-85.

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7 January 2021

Hypoxia as a target for combined modality treatments.

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7 January 2021

Tirapazamine, Cisplatin, and Radiation versus Fluorouracil, Cisplatin, and Radiation in patients with locally advanced head and neck cancer: a randomized phase II trial of the Trans-Tasman Radiation Oncology Group (TROG 98.02).

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7 January 2021

Predictive assays: will they ever have a role in the clinic?

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7 January 2021

Molecular marker profiles predict locoregional control of head and neck squamous cell carcinoma in a randomized trial of continuous hyperfractionated accelerated radiotherapy

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7 January 2021

Molecular profiles as predictive marker for the effect of overall treatment time of radiotherapy in supraglottic larynx squamous cell carcinomas.

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7 January 2021

Gene profiling in squamous cell carcinoma of the head and neck

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7 January 2021

Tissue oxygen distribution in head and neck cancer patients

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7 January 2021

Comparison of the comet assay and the oxygen microelectrode for measuring tumor oxygenation in head-and-neck cancer patients

1 reference

7 January 2021

The human tumor microenvironment: invasive (needle) measurement of oxygen and interstitial fluid pressure

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7 January 2021

Utility of FMISO PET in advanced head and neck cancer treated with chemoradiation incorporating a hypoxia-targeting chemotherapy agent

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7 January 2021

Non-invasive vascular imaging: assessing tumour vascularity

1 reference

7 January 2021

Dynamic contrast enhanced magnetic resonance scanning as a predictor of response to accelerated radiotherapy for advanced head and neck cancer

1 reference

7 January 2021

Effects of breathing a hyperoxic hypercapnic gas mixture on blood oxygenation and vascularity of head-and-neck tumors as measured by magnetic resonance imaging

1 reference

7 January 2021

Hypoxic induction of HIF-1alpha and VEGF expression in head and neck squamous cell carcinoma lines is mediated by stress activated protein kinases

1 reference

7 January 2021

Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension

1 reference

7 January 2021

Induction of HIF-1alpha in response to hypoxia is instantaneous

1 reference

7 January 2021

The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis

1 reference

7 January 2021

The von Hippel-Lindau tumor suppressor, hypoxia-inducible factor-1 (HIF-1) degradation, and cancer pathogenesis.

1 reference

7 January 2021

Hypoxia inducible factor-1: a novel target for cancer therapy

1 reference

7 January 2021

Hypoxia, clonal selection, and the role of HIF-1 in tumor progression

1 reference

7 January 2021

Hypoxia-inducible factor (HIF1A and HIF2A), angiogenesis, and chemoradiotherapy outcome of squamous cell head-and-neck cancer

1 reference

7 January 2021

Glucose requirement for hypoxic accumulation of hypoxia-inducible factor-1alpha (HIF-1alpha).

1 reference

7 January 2021

HIF-1A, pimonidazole, and iododeoxyuridine to estimate hypoxia and perfusion in human head-and-neck tumors

1 reference

7 January 2021

Human carbonic anhydrases and carbonic anhydrase deficiencies

1 reference

7 January 2021

Human MN/CA9 gene, a novel member of the carbonic anhydrase family: structure and exon to protein domain relationships

1 reference

7 January 2021

Diagnostic, prognostic and therapeutic implications of carbonic anhydrases in cancer

1 reference

7 January 2021

Transcriptional response to hypoxia in human tumors

1 reference

7 January 2021

The prognostic value of the hypoxia markers CA IX and GLUT 1 and the cytokines VEGF and IL 6 in head and neck squamous cell carcinoma treated by radiotherapy +/- chemotherapy

1 reference

7 January 2021

Tumor hypoxia at the micro-regional level: clinical relevance and predictive value of exogenous and endogenous hypoxic cell markers

1 reference

7 January 2021

Expression of glucose transporters in head-and-neck tumors.

1 reference

7 January 2021

Prognostic value of facilitative glucose transporter Glut-1 in oral squamous cell carcinomas treated by surgical resection; results of EORTC Translational Research Fund studies

1 reference

7 January 2021

Microregional expression of glucose transporter-1 and oxygenation status: lack of correlation in locally advanced cervical cancers

1 reference

7 January 2021

GLUT-1 and CAIX as intrinsic markers of hypoxia in carcinoma of the cervix: relationship to pimonidazole binding.

1 reference

7 January 2021

Glut3 expression in biopsy specimens of laryngeal carcinoma is associated with poor survival

1 reference

7 January 2021

The prognostic value of endogenous hypoxia-related markers for head and neck squamous cell carcinomas treated with ARCON

1 reference

7 January 2021

Erythropoietin receptor. Subunit structure and activation

1 reference

7 January 2021

The molecular biology of erythropoietin

1 reference

7 January 2021

Erythropoietin and the nervous system

1 reference

7 January 2021

Estrogen-dependent production of erythropoietin in uterus and its implication in uterine angiogenesis

1 reference

7 January 2021

Immunohistochemical expression of erythropoietin and erythropoietin receptor in breast carcinoma

1 reference

7 January 2021

Autocrine erythropoietin signaling inhibits hypoxia-induced apoptosis in human breast carcinoma cells

1 reference

7 January 2021

Erythropoietin receptor is not a surrogate marker for tumor hypoxia and does not correlate with survival in head and neck squamous cell carcinomas

1 reference

7 January 2021

Maintaining normal hemoglobin levels with epoetin alfa in mainly nonanemic patients with metastatic breast cancer receiving first-line chemotherapy: a survival study

1 reference

7 January 2021

Erythropoietin to treat head and neck cancer patients with anaemia undergoing radiotherapy: randomised, double-blind, placebo-controlled trial

1 reference

7 January 2021

Identification of hypoxia-regulated proteins in head and neck cancer by proteomic and tissue array profiling.

1 reference

7 January 2021

Evidence that involucrin, a marker for differentiation, is oxygen regulated in human squamous cell carcinomas

1 reference

7 January 2021

The hypoxia-regulated transcription factor DEC1 (Stra13, SHARP-2) and its expression in human tissues and tumours

1 reference

7 January 2021

Lactate dehydrogenase-5 (LDH-5) overexpression in non-small-cell lung cancer tissues is linked to tumour hypoxia, angiogenic factor production and poor prognosis

1 reference

7 January 2021

Activating transcription factor 4 is translationally regulated by hypoxic stress

1 reference

7 January 2021

Plasma osteopontin, hypoxia, and response to the hypoxia sensitiser nimorazole in radiotherapy of head and neck cancer: results from the DAHANCA 5 randomised double-blind placebo-controlled trial.

1 reference

7 January 2021

Studies with bromodeoxyuridine in head and neck cancer and accelerated radiotherapy

1 reference

7 January 2021

Vascular architecture and hypoxic profiles in human head and neck squamous cell carcinomas

1 reference

7 January 2021

Vascular architecture, hypoxia, and proliferation in first-generation xenografts of human head-and-neck squamous cell carcinomas

1 reference

7 January 2021

Changes in tumor hypoxia measured with a double hypoxic marker technique

1 reference

7 January 2021

Hypoxic cell turnover in different solid tumor lines

1 reference

7 January 2021

Repopulation of cancer cells during therapy: an important cause of treatment failure

1 reference

7 January 2021

Prognostic value of cell proliferation markers, tumour suppressor proteins and cell adhesion molecules in primary squamous cell carcinoma of the larynx and hypopharynx

1 reference

7 January 2021

The value of pretreatment cell kinetic parameters as predictors for radiotherapy outcome in head and neck cancer: a multicenter analysis

1 reference

7 January 2021

Patterns of proliferation related to vasculature in human head-and-neck carcinomas before and after transplantation in nude mice.

1 reference

7 January 2021

Distribution of hypoxia and proliferation associated markers in spontaneous canine tumors

1 reference

7 January 2021

Identifiers

DOI

10.1002/HED.20543

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15 August 2017

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