(Q36731464)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17288549%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

review article

1 reference

title

Molecular basis of cerebral neurodegeneration in prion diseases (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17288549%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

0 references

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17288549%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

Hermann M. Schätzl

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17288549%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

2

Hermann M Schätzl

1 reference

15 August 2017

language of work or name

English

0 references

publication date

1 February 2007

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17288549%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17288549%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

volume

274

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17288549%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

issue

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17288549%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

page(s)

606-611

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17288549%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05633.X

Mammalian prion biology: one century of evolving concepts

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05633.X

PrP knock-out and PrP transgenic mice in prion research

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05633.X

Prion diseases of humans and animals: their causes and molecular basis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05633.X

Prion diseases: from molecular biology to intervention strategies

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05633.X

Normal host prion protein necessary for scrapie-induced neurotoxicity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05633.X

Depleting neuronal PrP in prion infection prevents disease and reverses spongiosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05633.X

Biogenesis and transmembrane orientation of the cellular isoform of the scrapie prion protein [published errratum appears in Mol Cell Biol 1987 May;7(5):2035]

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05633.X

A transmembrane form of the prion protein in neurodegenerative disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05633.X

Transmissible and genetic prion diseases share a common pathway of neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05633.X

Neurodegenerative illness in transgenic mice expressing a transmembrane form of the prion protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05633.X

Non-hydrophobic extracytoplasmic determinant of stop transfer in the prion protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05633.X

Post-translational import of the prion protein into the endoplasmic reticulum interferes with cell viability: a critical role for the putative transmembrane domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05633.X

Neurotoxicity and neurodegeneration when PrP accumulates in the cytosol

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05633.X

Molecular morphology and toxicity of cytoplasmic prion protein aggregates in neuronal and non-neuronal cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05633.X

Association of Bcl-2 with misfolded prion protein is linked to the toxic potential of cytosolic PrP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05633.X

Protection from cytosolic prion protein toxicity by modulation of protein translocation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05633.X

The interaction between cytoplasmic prion protein and the hydrophobic lipid core of membrane correlates with neurotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05633.X

Cytosolic prion protein (PrP) is not toxic in N2a cells and primary neurons expressing pathogenic PrP mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05633.X

Cytosolic prion protein is not toxic and protects against Bax-mediated cell death in human primary neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05633.X

Wild-type PrP and a mutant associated with prion disease are subject to retrograde transport and proteasome degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05633.X

Proteasomes and ubiquitin are involved in the turnover of the wild-type prion protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05633.X

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05633.X

Loss of cerebellar Purkinje cells in aged mice homozygous for a disrupted PrP gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05633.X

Ataxia in prion protein (PrP)-deficient mice is associated with upregulation of the novel PrP-like protein doppel

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05633.X

Physiological expression of the gene for PrP-like protein, PrPLP/Dpl, by brain endothelial cells and its ectopic expression in neurons of PrP-deficient mice ataxic due to Purkinje cell degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05633.X

Onset of ataxia and Purkinje cell loss in PrP null mice inversely correlated with Dpl level in brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05633.X

Two different neurodegenerative diseases caused by proteins with similar structures

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05633.X

Expression of truncated PrP targeted to Purkinje cells of PrP knockout mice causes Purkinje cell death and ataxia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05633.X

Expression of amino-terminally truncated PrP in the mouse leading to ataxia and specific cerebellar lesions

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05633.X

A pathogenic PrP mutation and doppel interfere with polarized sorting of the prion protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05633.X

Genetic mapping of activity determinants within cellular prion proteins: N-terminal modules in PrPC offset pro-apoptotic activity of the Doppel helix B/B' region

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05633.X

Doppel-induced cerebellar degeneration in transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05633.X

Doppel-induced apoptosis and counteraction by cellular prion protein in neuroblastoma and astrocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05633.X

Prion protein accumulation and neuroprotection in hypoxic brain damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05633.X

Overexpression of PrPC by adenovirus-mediated gene targeting reduces ischemic injury in a stroke rat model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05633.X

Aggravation of ischemic brain injury by prion protein deficiency: role of ERK-1/-2 and STAT-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05633.X

Deletion of cellular prion protein results in reduced Akt activation, enhanced postischemic caspase-3 activation, and exacerbation of ischemic brain injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05633.X

Prion protein (PrPc) positively regulates neural precursor proliferation during developmental and adult mammalian neurogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05633.X

Prion protein is expressed on long-term repopulating hematopoietic stem cells and is important for their self-renewal

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05633.X

Conversion of truncated and elongated prion proteins into the scrapie isoform in cultured cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05633.X

Anchorless prion protein results in infectious amyloid disease without clinical scrapie

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05633.X

Determinants of the in vivo folding of the prion protein. A bipartite function of helix 1 in folding and aggregation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05633.X