(Q36746390)

16 August 2017

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title

'Magic bullets' for bone diseases: progress in rational design of bone-seeking medicinal agents (English)

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16 August 2017

Sufeng Zhang

1

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16 August 2017

Geeti Gangal

series ordinal

2

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16 August 2017

Hasan Uludağ

series ordinal

3

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16 August 2017

publication date

14 September 2006

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16 August 2017

published in

Chemical Society Reviews

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16 August 2017

volume

36

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16 August 2017

issue

3

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16 August 2017

page(s)

507-531

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Bone as an effect compartment : models for uptake and release of drugs.

16 August 2017

cites work

1 reference

Effect of pyrophosphate on hydroxyapatite and its implications in calcium homeostasis

21 January 2018

1 reference

Inhibition of aortic calcification by means of pyrophosphate and polyphosphates

21 January 2018

1 reference

Diphosphonates inhibit formation of calcium phosphate crystals in vitro and pathological calcification in vivo.

21 January 2018

1 reference

Diphosphonates in the treatment of myositis ossificans.

21 January 2018

1 reference

Synthesis, antitumor activity, distribution and toxicity of 4-[4-[bis(2-chloroethyl)amino]phenyl]-1-hydroxybutane-1 1-bisphosphonic acid (BAD), a new lost derivative with increased accumulation in rat osteosarcoma

21 January 2018

1 reference

Bisphosphonates as a foundation of drug delivery to bone

21 January 2018

1 reference

Designing proteins for bone targeting

21 January 2018

1 reference

Bone-specific drug delivery systems: approaches via chemical modification of bone-seeking agents

21 January 2018

1 reference

Highly potent geminal bisphosphonates. From pamidronate disodium (Aredia) to zoledronic acid (Zometa).

21 January 2018

1 reference

Biological and medical significance of calcium phosphates

21 January 2018

1 reference

Nanoscale variation in surface charge of synthetic hydroxyapatite detected by chemically and spatially specific high-resolution force spectroscopy.

21 January 2018

1 reference

Use of Self-Assembled Monolayers as Substrates for Atomic Force Imaging of Hydroxyapatite Crystals from Mammalian Skeletal Tissues

21 January 2018

1 reference

The COOH terminus of the amelogenin, LRAP, is oriented next to the hydroxyapatite surface

21 January 2018

1 reference

Analysis of Hydroxyapatite Surface Coverage by Amelogenin Nanospheres Following the Langmuir Model for Protein Adsorption

21 January 2018

1 reference

Binding of Matrix Proteins to Developing Enamel Crystals: An Atomic Force Microscopy Study

21 January 2018

1 reference

Binding of dentin noncollagenous matrix proteins to biological mineral crystals: an atomic force microscopy study

21 January 2018

1 reference

Nanoscale probing of the enamel nanorod surface using polyamidoamine dendrimers.

21 January 2018

1 reference

The pharmacology of bisphosphonates and new insights into their mechanisms of action

21 January 2018

1 reference

Alendronate zwitterions bind to calcium cations arranged in columns.

21 January 2018

1 reference

The calcium-binding properties of pamidronate, a bone-resorption inhibitor.

21 January 2018

1 reference

Synthesis and biological evaluation of 1-amino-1,1-bisphosphonates derived from fatty acids against Trypanosoma cruzi targeting farnesyl pyrophosphate synthase

21 January 2018

1 reference

Novel insights into actions of bisphosphonates on bone: differences in interactions with hydroxyapatite

21 January 2018

1 reference

Synthesis of a new bisphosphonic acid ligand (SEDP) and preparation of a (188)Re-(Sn)SEDP bone seeking radiotracer

21 January 2018

1 reference

Relationship between physicochemical and osteotropic properties of bisphosphonic derivatives: rational design for osteotropic drug delivery system (ODDS).

21 January 2018

1 reference

Bone scintigraphy in common tumors with osteolytic components

21 January 2018

1 reference

Incidental finding of meningioma on bone scintigraphy.

21 January 2018

1 reference

Splenic accumulation of Tc-99m HMDP in a patient with severe alcoholic cirrhosis of the liver

21 January 2018

1 reference

Tc-99m MDP uptake resulting from acute middle cerebral artery territory infarction

21 January 2018

1 reference

Extraosseous uptake of metastatic lymph nodes of ureteral cancer on 99Tcm hydroxymethylene diphosphonate bone scintigraphy

21 January 2018

1 reference

Predictors of a positive baseline bone scan in breast cancer

21 January 2018

1 reference

Intracranial meningioma with abnormal localization of bone-seeking radiopharmaceutical: correlation with gross and microscopic pathology

21 January 2018

1 reference

High activity Rhenium-186 HEDP with autologous peripheral blood stem cell rescue: a phase I study in progressive hormone refractory prostate cancer metastatic to bone

21 January 2018

1 reference

The use of SPECT to evaluate growth cessation of the mandible in unilateral condylar hyperplasia.

21 January 2018

1 reference

Development of a rhenium-186-labeled MAG3-conjugated bisphosphonate for the palliation of metastatic bone pain based on the concept of bifunctional radiopharmaceuticals

21 January 2018

1 reference

In vivo near-infrared fluorescence imaging of osteoblastic activity

21 January 2018

1 reference

Near-infrared fluorescence imaging of microcalcification in an animal model of breast cancer

21 January 2018

1 reference

A bisphosphonate monoamide analogue of DOTA: a potential agent for bone targeting

21 January 2018

1 reference

Clinical studies of three oral prodrugs of 5-fluorouracil (capecitabine, UFT, S-1): a review

21 January 2018

1 reference

188Re-labeled bisphosphonates as potential bifunctional agents for therapy in patients with bone metastases

21 January 2018

1 reference

Preclinical evidence for the effect of bisphosphonates and cytotoxic drugs on tumor cell invasion

21 January 2018

1 reference

Bisphosphonates and cancer-induced bone disease: beyond their antiresorptive activity

21 January 2018

1 reference

A novel non-containing-nitrogen bisphosphonate inhibits both in vitro and in vivo angiogenesis

21 January 2018

1 reference

Osteoadsorptive bisphosphonate derivatives of fluoroquinolone antibacterials

21 January 2018

1 reference

Bisphosphonate-ciprofloxacin bound to Skelite is a prototype for enhancing experimental local antibiotic delivery to injured bone

21 January 2018

1 reference

Src kinase activity is essential for osteoclast function

21 January 2018

1 reference

Src kinase activation by direct interaction with the integrin β cytoplasmic domain

21 January 2018

1 reference

Targeting protein kinases for bone disease: discovery and development of Src inhibitors

21 January 2018

1 reference

A novel inhibitor of the tyrosine kinase Src suppresses phosphorylation of its major cellular substrates and reduces bone resorption in vitro and in rodent models in vivo

21 January 2018

1 reference

Structure-based design of an osteoclast-selective, nonpeptide src homology 2 inhibitor with in vivo antiresorptive activity

21 January 2018

1 reference

Bone-targeted pyrido[2,3-d]pyrimidin-7-ones: potent inhibitors of Src tyrosine kinase as novel antiresorptive agents

21 January 2018

1 reference

Bone-targeted 2,6,9-trisubstituted purines: novel inhibitors of Src tyrosine kinase for the treatment of bone diseases

21 January 2018

1 reference

Bone-targeted Src kinase inhibitors: novel pyrrolo- and pyrazolopyrimidine analogues

21 January 2018

1 reference

Synthesis of NO-donor bisphosphonates and their in-vitro action on bone resorption.

21 January 2018

1 reference

Synthesis and evaluation of water-soluble polymeric bone-targeted drug delivery systems.

21 January 2018

1 reference

Imparting bone mineral affinity to osteogenic proteins through heparin-bisphosphonate conjugates

21 January 2018

1 reference

Pre-clinical in vitro and in vivo studies to examine the potential use of photodynamic therapy in the treatment of osteomyelitis

21 January 2018

1 reference

Photodynamic therapy for the treatment of metastatic lesions in bone: studies in rat and porcine models.

21 January 2018

1 reference

In vivo killing of Porphyromonas gingivalis by toluidine blue-mediated photosensitization in an animal model

21 January 2018

1 reference

Surface chemistry of enamel apatite during maturation in relation to pH: implications for protein removal and crystal growth.

21 January 2018

1 reference

Inhibition of hydroxyapatite formation by osteopontin phosphopeptides

21 January 2018

1 reference

Delineation of the hydroxyapatite-nucleating domains of bone sialoprotein

21 January 2018

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Structural characterization of human recombinant and bone-derived bone sialoprotein. Functional implications for cell attachment and hydroxyapatite binding

21 January 2018

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The effect of the addition of a polyglutamate motif to RGD on peptide tethering to hydroxyapatite and the promotion of mesenchymal stem cell adhesion

21 January 2018

1 reference

Enhancement of osteogenesis on hydroxyapatite surface coated with synthetic peptide (EEEEEEEPRGDT) in vitro

21 January 2018

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Selective drug delivery system to bone: small peptide (Asp)6 conjugation

21 January 2018

1 reference

Bone recognition mechanism of porcine osteocalcin from crystal structure

21 January 2018

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Characterization of native and recombinant bone sialoprotein: delineation of the mineral-binding and cell adhesion domains and structural analysis of the RGD domain

21 January 2018

1 reference

Importance of phosphorylation for osteopontin regulation of biomineralization

21 January 2018

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Cross-linking of osteopontin by tissue transglutaminase increases its collagen binding properties

21 January 2018

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Imparting mineral affinity to proteins with thiol-labile disulfide linkages

21 January 2018

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Imparting bone affinity to glycoproteins through the conjugation of bisphosphonates

21 January 2018

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Engineering temperature-sensitive poly(N-isopropylacrylamide) polymers as carriers of therapeutic proteins

21 January 2018

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Impact of tether length on bone mineral affinity of protein-bisphosphonate conjugates

21 January 2018

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A di(bisphosphonic acid) for protein coupling and targeting to bone

21 January 2018

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A dendritic tetra(bisphosphonic acid) for improved targeting of proteins to bone.

21 January 2018

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A comparison of mineral affinity of bisphosphonate-protein conjugates constructed with disulfide and thioether linkages

21 January 2018

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Bisphosphonates: a review of their pharmacokinetic properties

21 January 2018

1 reference

Imparting mineral affinity to fetuin by bisphosphonate conjugation: a comparison of three bisphosphonate conjugation schemes

21 January 2018

1 reference

Cleavage of disulfide-linked fetuin-bisphosphonate conjugates with three physiological thiols

21 January 2018

1 reference

Optimization of tether length in nonglycosidically linked bivalent ligands that target sites 2 and 1 of a Shiga-like toxin

21 January 2018

1 reference

Dual-site binding of bivalent 4-aminopyridine- and 4-aminoquinoline-based AChE inhibitors: contribution of the hydrophobic alkylene tether to monomer and dimer affinities

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1039/B512310K

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16 August 2017

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