(Q36772561)

English

Enantiomeric separation and determination of absolute stereochemistry of asymmetric molecules in drug discovery: building chiral technology toolboxes

scientific article published on September 2007

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scholarly article

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Europe PubMed Central

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16 August 2017

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Europe PubMed Central

Enantiomeric separation and determination of absolute stereochemistry of asymmetric molecules in drug discovery: building chiral technology toolboxes (English)

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Europe PubMed Central

PubMed publication ID

16 August 2017

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author name string

Oliver McConnell

1

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16 August 2017

Alvin Bach

2

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16 August 2017

Carl Balibar

3

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16 August 2017

Neal Byrne

4

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16 August 2017

Yanxuan Cai

5

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16 August 2017

Guy Carter

6

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16 August 2017

Michael Chlenov

7

1 reference

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16 August 2017

Li Di

8

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16 August 2017

Kristi Fan

9

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16 August 2017

Igor Goljer

10

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16 August 2017

Yanan He

11

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16 August 2017

Don Herold

12

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16 August 2017

Michael Kagan

13

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16 August 2017

Edward Kerns

14

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16 August 2017

Frank Koehn

15

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16 August 2017

Christina Kraml

16

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16 August 2017

Vasilios Marathias

17

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16 August 2017

Brian Marquez

18

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16 August 2017

Leonard McDonald

19

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16 August 2017

Lisa Nogle

20

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16 August 2017

Christopher Petucci

21

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16 August 2017

Gerhard Schlingmann

22

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16 August 2017

Gregory Tawa

23

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16 August 2017

Mark Tischler

24

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16 August 2017

R Thomas Williamson

25

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16 August 2017

Alan Sutherland

26

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16 August 2017

William Watts

27

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16 August 2017

Mairead Young

28

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16 August 2017

Mei-Yi Zhang

29

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16 August 2017

Yingru Zhang

30

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16 August 2017

Dahui Zhou

31

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16 August 2017

Douglas Ho

32

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16 August 2017

publication date

1 September 2007

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16 August 2017

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16 August 2017

19

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16 August 2017

9

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16 August 2017

658-682

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16 August 2017

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1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

CDK2/cyclinA inhibitors: targeting the cyclinA recruitment site with small molecules derived from peptide leads

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

Discovery of S-[5-amino-1-(4-fluorophenyl)-1H-pyrazol-4-yl]-[3-(2,3-dihydroxypropoxy)phenyl]methanone (RO3201195), an orally bioavailable and highly selective inhibitor of p38 MAP kinase

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

Development and use of hydrophobic surface area (HSA) descriptors for computer-assisted quantitative structure-activity and structure-property relationship studies

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

Separation of enantiomers: needs, challenges, perspectives.

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

Putting chirality to work: the strategy of chiral switches

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

Chiral switches

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

Intellectual property and chirality of drugs

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

FDA's policy statement for the development of new stereoisomeric drugs

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

Absolute stereochemistry of unusual biopolymers from Ascomycete culture LL-W1278: examples that derivatives of (S)-6-hydroxymellein are also natural fungal metabolites

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

Additional pyrrolomycins from cultures of Streptomyces fumanus

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

Assignment of absolute configuration of chiral carboxylic acids via exciton-coupled CD treatment: 4-phenylthioproline as a case study

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

Some applications of a chiral fluorometric reagent, (S)-TBMB carboxylic acid

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

Absolute stereochemistry of dihydrofuroangelicins bearing C-8 substituted double bonds: a combined chemical/exciton chirality protocol

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

Absolute stereochemistry of allylic alcohols, amines, and other ene moieties: a microscale cross metathesis/exciton chirality protocol

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

Three challenges toward the assignment of absolute configuration of gymnocin-B

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

.alpha.-Methoxy-.alpha.-trifluoromethylphenylacetic acid, a versatile reagent for the determination of enantiomeric composition of alcohols and amines

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

The Assignment of Absolute Configuration by NMR

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

A practical guide for the assignment of the absolute configuration of alcohols, amines and carboxylic acids by NMR

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

Total Synthesis of Nominal Diazonamides-Part 2: On the True Structure and Origin of Natural Isolates Funding provided by the NIH (RO1-GM60591), the NSF (CAREER 9984282), the Howard Hughes Medical Institute (junior faculty support), the Robert A. Wel

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

Synthesis and biological evaluation of benzodioxanylpiperazine derivatives as potent serotonin 5-HT(1A) antagonists: the discovery of Lecozotan

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

Muraymycins, novel peptidoglycan biosynthesis inhibitors: synthesis and SAR of their analogues

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

Use of bis-(chiral alpha-methylbenzyl)glycine esters for synthesis of enantiopure beta-hydroxyamino esters

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

Absolute stereochemistry of the strevertenes

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

Enantioselective chromatography as a powerful alternative for the preparation of drug enantiomers

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

Enantioselective chromatography in drug discovery

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

Evaluation of generic chiral liquid chromatography screens for pharmaceutical analysis

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

Preparative chiral chromatographic resolution of enantiomers in drug discovery

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

CHIRBASE, a graphical molecular database on the separation of enantiomers by liquid-, supercritical fluid-, and gas chromatography

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

CHIRBASE, a molecular database for the separation of enantiomers by chromatography

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

An approach to discriminating 25 commercial chiral stationary phases from structural data sets extracted from a molecular database

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

Reviewing mobile phases used on Chiralcel OD through an application of data mining tools to CHIRBASE database.

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

Enantiophore modeling in 3D-QSAR. A data mining application on Whelk-O1 chiral stationary phase

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

Enantioselective chromatography and molecular modeling of novel aryloxyaminopropan-2-ols with the alkyl carbamate function

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

Theoretical reassessment of Whelk-O1 as an enantioselective receptor for 1-(4-halogeno-phenyl)-1-ethylamine derivatives

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

Probability rule for chiral recognition

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

Prediction of enantioselectivity using chirality codes and Classification and Regression Trees

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

Impact of normal-phase gradient elution in chiral chromatography: a novel, robust, efficient and rapid chiral screening procedure

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

Screening approach for chiral separation of pharmaceuticals. Part I. Normal-phase liquid chromatography

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

Definition and system implementation of strategies for method development of chiral separations in normal- or reversed-phase liquid chromatography using polysaccharide-based stationary phases

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

The role of nucleation inhibition in optical resolutions with families of resolving agents

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

The Family Approach to the Resolution of Racemates

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

Chiral separations by capillary electromigration techniques in nonaqueous media. I. Enantioselective nonaqueous capillary electrophoresis

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

Chiral separations by capillary electromigration techniques in nonaqueous media. II. Enantioselective nonaqueous capillary electrochromatography

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

Recent progress in enantiomeric separation by capillary electrochromatography

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

Selected fundamental aspects of chiral electromigration techniques and their application to pharmaceutical and biomedical analysis

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

Improved quantification limits in chiral capillary electrochromatography by peak compression effects

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

Combining the enantioselectivities of L-valine diamide and permethylated beta-cyclodextrin in one gas chromatographic chiral stationary phase

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

Contributions to the theory and practice of the chromatographic separation of enantiomers

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

Separation of stereoisomers of several furan derivatives by capillary gas chromatography-mass spectrometry, supercritical fluid chromatography, and liquid chromatography using chiral stationary phases.

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

Separation of enantiomers by gas chromatography

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

The development of a semi-preparatory scale supercritical-fluid chromatograph for high-throughput purification of 'combi-chem' libraries

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

Direct HPLC enantioseparation of chiral aptazepine derivatives on coated and immobilized polysaccharide-based chiral stationary phases

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

Application and comparison of immobilized and coated amylose tris-(3,5-dimethylphenylcarbamate) chiral stationary phases for the enantioselective separation of beta-blockers enantiomers by liquid chromatography.

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

Screening approach for chiral separation of pharmaceuticals. Part III. Supercritical fluid chromatography for analysis and purification in drug discovery

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

Integration of supercritical fluid chromatography into drug discovery as a routine support tool. Part I. fast chiral screening and purification

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

The effect of acidic and basic additives on the enantioseparation of basic drugs using polysaccharide-based chiral stationary phases

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

Reversal of elution order for profen acid enantiomers in packed-column SFC on Chiralpak AD.

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

True or apparent reversal of elution order during chiral high-performance liquid chromatography monitored by a polarimetric detector under different mobile phase conditions

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

Reversal of elution order during the chiral separation in high performance liquid chromatography

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

Simulated moving columns technique for chiral liquid chromatography.

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

Simulated moving bed chromatography (SMB) for application in bioseparation.

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

Modification of a commercial chiral stationary phase influences on enantiomer separations using simulated moving bed chromatography

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

Simulated moving-bed chromatography and its application to chirotechnology

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

Rapid method development for chiral separation in drug discovery using multi-column parallel screening and circular dichroism signal pooling

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

Normal-phase high-performance liquid chromatographic separations using ethoxynonafluorobutane as hexane alternative. I. Analytical and chiral applications

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

Normal-phase high-performance liquid chromatographic separations using ethoxynonafluorobutane as hexane alternative. II. Liquid chromatography-atmospheric pressure chemical ionization-mass spectrometry applications with methanol gradients

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

Evaluation of ethoxynonafluorobutane as a safe and environmentally friendly solvent for chiral normal-phase LC-atmospheric pressure chemical ionization/electrospray ionization-mass spectrometry

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

Normal-phase chiral liquid chromatography-mass spectrometry of non-UV-active compounds: applications for pharmaceutically relevant racemates

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

Advantages of atmospheric pressure photoionization mass spectrometry in support of drug discovery

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

Enhanced chromatographic resolution of amine enantiomers as carbobenzyloxy derivatives in high-performance liquid chromatography and supercritical fluid chromatography

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

Preparative separation and identification of derivatized beta-methylphenylalanine enantiomers by chiral SFC, HPLC and NMR for development of new peptide ligand mimetics in drug discovery

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

Developments and trends in enzyme catalysis in nonconventional media

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

Enzymes for chemical synthesis

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

Improving enzymes by using them in organic solvents

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

Enzymatic resolution, desymmetrization, and dynamic kinetic asymmetric transformation of 1,3-cycloalkanediols

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

Efficient kinetic resolution of (R,S)-1-trimethylsilylethanol via lipase-mediated enantioselective acylation in ionic liquids

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

Enantioselective synthesis of 2-alkylidenetetrahydrofurans based on a ‘cyclization/enzymatic resolution’ strategy

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

Absolute configurational assignments of secondary amines by CD-sensitive dimeric zinc porphyrin host

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

Chiral Recognition by CD-Sensitive Dimeric Zinc Porphyrin Host. 1. Chiroptical Protocol for Absolute Configurational Assignments of Monoalcohols and Primary Monoamines

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

Chiral recognition by CD-sensitive dimeric zinc porphyrin host. 2. Structural studies of host-guest complexes with chiral alcohol and monoamine conjugates

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

Porphyrins and metalloporphyrins: versatile circular dichroic reporter groups for structural studies

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

Absolute configuration determination of chiral molecules in the solution state using vibrational circular dichroism

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

Elucidation of the absolute configuration of JNJ-27553292, a CCR2 receptor antagonist, by vibrational circular dichroism analysis of two precursors.

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

Determination of the absolute configuration and solution conformation of a novel disubstituted pyrrolidine acid A by vibrational circular dichroism.

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

Chirality of camphor derivatives by density functional theory

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

Theoretical simulation of the electronic circular dichroism spectrum of calicheamicin

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

Hyperolactone C: determination of its absolute configuration by comparison of experimental and calculated CD spectra

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

Structural determinations by circular dichroism spectra analysis using coupled oscillator methods: an update of the applications of the DeVoe polarizability model

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

Protocols for the analysis of theoretical optical rotations

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

Intrinsic rotation and molecular structure.

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

Optical rotation: recent advances in determining the absolute configuration

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

Determination of the absolute configuration of flexible molecules by ab initio ORD calculations: a case study with cytoxazones and isocytoxazones

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

Determination of absolute configurations of chiral molecules using ab initio time-dependent Density Functional Theory calculations of optical rotation: how reliable are absolute configurations obtained for molecules with small rotations?

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

Determination of absolute configuration using density functional theory calculation of optical rotation: chiral alkanes

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

Determination of absolute configuration using ab initio calculation of optical rotation

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

Determination of absolute configuration using optical rotation calculated using density functional theory

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

Solvent effects on the conformational distribution and optical rotation of gamma-methyl paraconic acids and esters.

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

Determining absolute configuration in flexible molecules: a case study

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

Stereochemical determination and bioactivity assessment of (S)-(+)-curcuphenol dimers isolated from the marine sponge Didiscus aceratus and synthesized through laccase biocatalysis

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

Determination of the absolute configuration and solution conformation of gossypol by vibrational circular dichroism

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

Determination of molecular structure in solution using vibrational circular dichroism spectroscopy: the supramolecular tetramer of S-2,2'-dimethyl-biphenyl-6,6'-dicarboxylic acid

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

Determination of the absolute configuration and solution conformation of the antifungal agents ketoconazole, itraconazole, and miconazole with vibrational circular dichroism

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

VCD configuration of enantiopure/-enriched tetrasubstituted alpha-fluoro cyclohexanones and their use for epoxidation of trans-olefins.

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

(3R,4S)-4-(4-Fluorophenyl)-3-hydroxymethyl-1-methylpiperidine: conformation and structure monitoring by vibrational circular dichroism

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

Determination of enantiomeric excess in samples of chiral molecules using fourier transform vibrational circular dichroism spectroscopy: simulation of real-time reaction monitoring

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

Structural studies on McN-5652-X, a high-affinity ligand for the serotonin transporter in mammalian brain

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

Fourier transform near-infrared vibrational circular dichroism used for on-line monitoring the epimerization of 2,2-dimethyl-1,3-dioxolane-4-methanol: A pseudo racemization reaction

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

Absolute configurations of brominated sesquiterpenes determined by vibrational circular dichroism.

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

VCD spectroscopic investigation of enantiopure cyclic beta-lactams obtained through Lipolase-catalyzed enantioselective ring-opening reaction

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

Absolute configurations of chiral herbicides determined from vibrational circular dichroism.

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

Absolute configuration and predominant conformations of 1,1-dimethyl-2-phenylethyl phenyl sulfoxide.

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

Absolute configuration of C2-symmetric spiroselenurane: 3,3,3',3'-tetramethyl-1,1'-spirobi[3 H,2,1]benzoxaselenole

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

Determination of absolute configuration using concerted ab Initio DFT calculations of electronic circular dichroism and optical rotation: bicyclo[3.3.1]nonane diones

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

Determination of the absolute configuration of [3(2)](1,4)barrelenophanedicarbonitrile using concerted time-dependent density functional theory calculations of optical rotation and electronic circular dichroism

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

Determination of molecular structure using vibrational circular dichroism spectroscopy: the keto-lactone product of Baeyer-Villiger oxidation of (+)-(1R,5S)-bicyclo[3.3.1]nonane-2,7-dione.

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

Determination of the absolute configuration of Anisotome irregular diterpenes: application of CD and NMR methods

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

A stereochemical anomaly: the cyclised (R)-AMPA analogue (R)-3-hydroxy-4,5,6,7-tetrahydroisoxazolo[5,4-c]pyridine-5-carboxylic acid [(R)-5-HPCA] resembles (S)-AMPA at glutamate receptors

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

Etodolic acid and related compounds. Chemistry and antiinflammatory actions of some potent di- and trisubstituted 1,3,4,9-tetrahydropyrano[3,4-b]indole-1-acetic acids

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

Etodolac (1,8-diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indole-1-acetic acid): a potent antiinflammatory drug. Conformation and absolute configuration of its active enantiomer

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

New Silyl Ether Reagents for the Absolute Stereochemical Determination of Secondary Alcohols

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

Chiral silylation reagents for the determination of absolute configuration by NMR spectroscopy

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

Determining factors in the assignment of the absolute configuration of alcohols by NMR. The use of anisotropic effects on remote positions

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

MTPA vs MPA in the Determination of the Absolute Configuration of Chiral Alcohols by1H NMR

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

Determining the Absolute Stereochemistry of Secondary/Secondary Diols by1H NMR: Basis and Applications

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

Determination of absolute configuration of 1,3-diols by the modified Mosher's method using their di-MTPA esters

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

Assignment of the Absolute Configuration of β-Chiral Primary Alcohols by NMR: Scope and Limitations

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

Determination of the absolute configuration and enantiomeric purity of chiral primary alcohols by 1H NMR of 9-anthrylmethoxyacetates

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

(S)-2-[(R)-fluoro(phenyl)methyl]oxirane: a general reagent for determining the ee of alpha-chiral amines

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

Boc-Phenylglycine: The Reagent of Choice for the Assignment of the Absolute Configuration of α-Chiral Primary Amines by1H NMR Spectroscopy

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

Choosing the Right Reagent for the Determination of the Absolute Configuration of Amines by NMR: MTPA or MPA?†

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

Determination of the Absolute Stereochemistry of Chiral Amines by 1H NMR of Arylmethoxyacetic Acid Amides: The Conformational Model

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

“Mix and Shake” Method for Configurational Assignment by NMR: Application to Chiral Amines and Alcohols

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

Determination of the absolute stereochemistry of alcohols and amines by NMR of the group directly linked to the chiral derivatizing reagent

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

The use of ethyl 2-(9-anthryl)-2-hydroxyacetate for assignment of the absolute configuration of carboxylic acids by 1H NMR

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

Assignment of absolute configuration of 3-hydroxy beta-lactams by the NMR "mix and shake" method

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

MalphaNP acid, a powerful chiral molecular tool for preparation of enantiopure alcohols by resolution and determination of their absolute configurations by the (1)H NMR anisotropy method.

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

Practical enantioresolution of alcohols with 2-methoxy-2-(1-naphthyl)propionic acid and determination of their absolute configurations by the (1)H NMR anisotropy method

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

Simultaneous enantioresolution and assignment of absolute configuration of secondary alcohols by directly coupled HPLC–NMR of 9-AMA esters

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

Application of Mosher's method for absolute configuration assignment and resolution of 2-hydroxypyrrolizidinones.

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

Chiral reagents for the determination of enantiomeric excess and absolute configuration using NMR spectroscopy

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

Complete stereochemistry of tetrafibricin

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

Toward the creation of NMR databases in chiral solvents: bidentate chiral NMR solvents for assignment of the absolute configuration of acyclic secondary alcohols

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

Routine use of natural abundance deuterium NMR in a polypeptidic chiral oriented solvent for the determination of the enantiomeric composition of chiral building blocks

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

Acetyl-d(3) Chloride: A Convenient Nonchiral Derivatizing Agent (NCDA) for a Facile Enantiomeric Excess Determination of Amines through Deuterium NMR

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

Simultaneous determination of 1H-1H and 1H-13C residual dipolar couplings in a chiral liquid crystal solvent using a natural abundance HSQC experiment

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

Probing the Diastereotopicity of Methylene Protons in Strychnine Using Residual Dipolar Couplings

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

Simultaneous assignment of all diastereotopic protons in strychnine using RDCs: PELG as alignment medium for organic molecules

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

Measurement of long range H,C couplings in natural products in orienting media: a tool for structure elucidation of natural products

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

Crystal engineering of the composition of pharmaceutical phases.

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

A robust method for determining the magnitude of the fully asymmetric alignment tensor of oriented macromolecules in the absence of structural information

1 reference

https://api.crossref.org/works/10.1002%2FCHIR.20399

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1002/CHIR.20399

1 reference

Europe PubMed Central

PubMed publication ID

16 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

16 August 2017

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