(Q36777158)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17401151%20AND%20SRC:MED&resulttype=core&format=json

28 December 2019

review article

1 reference

title

Chaperones and proteases: cellular fold-controlling factors of proteins in neurodegenerative diseases and aging (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17401151%20AND%20SRC:MED&resulttype=core&format=json

28 December 2019

0 references

0 references

1 reference

2

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28 December 2019

author name string

Marie-Pierre Hinault

series ordinal

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17401151%20AND%20SRC:MED&resulttype=core&format=json

28 December 2019

Pierre Goloubinoff

series ordinal

3

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28 December 2019

language of work or name

1 reference

1 January 2006

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17401151%20AND%20SRC:MED&resulttype=core&format=json

Journal of Molecular Neuroscience

28 December 2019

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17401151%20AND%20SRC:MED&resulttype=core&format=json

28 December 2019

volume

30

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28 December 2019

issue

3

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17401151%20AND%20SRC:MED&resulttype=core&format=json

28 December 2019

page(s)

249-265

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17401151%20AND%20SRC:MED&resulttype=core&format=json

Proteinaceous infectious behavior in non-pathogenic proteins is controlled by molecular chaperones.

28 December 2019

cites work

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12 December 2020

Neuroinflammation: a potential therapeutic target

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12 December 2020

Inhibition of amyloid beta protein aggregation and neurotoxicity by rifampicin. Its possible function as a hydroxyl radical scavenger.

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12 December 2020

Induction of 68,000-dalton heat shock proteins by cyclopentenone prostaglandins. Its association with prostaglandin-induced G1 block in cell cycle progression

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12 December 2020

Serofendic acid prevents 6-hydroxydopamine-induced nigral neurodegeneration and drug-induced rotational asymmetry in hemi-parkinsonian rats

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12 December 2020

HSP27 but not HSP70 has a potent protective effect against alpha-synuclein-induced cell death in mammalian neuronal cells.

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12 December 2020

Regulation of signaling protein function and trafficking by the hsp90/hsp70-based chaperone machinery

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12 December 2020

Mutant Cu/Zn-superoxide dismutase proteins have altered solubility and interact with heat shock/stress proteins in models of amyotrophic lateral sclerosis

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12 December 2020

Hsp70 and hsp40 chaperones can inhibit self-assembly of polyglutamine proteins into amyloid-like fibrils

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12 December 2020

Stress management - heat shock protein-70 and the regulation of apoptosis

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12 December 2020

Chaperones increase association of tau protein with microtubules

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12 December 2020

Formation of nuclear HSF1 granules varies depending on stress stimuli

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12 December 2020

Sick chaperones, cellular stress, and disease

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12 December 2020

Estrogen and androgen protection of human neurons against intracellular amyloid beta1-42 toxicity through heat shock protein 70.

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12 December 2020

The endoplasmic reticulum chaperone glycoprotein GRP94 with Ca(2+)-binding and antiapoptotic properties is a novel proteolytic target of calpain during etoposide-induced apoptosis

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12 December 2020

Bimoclomol, a heat shock protein co-inducer, acts by the prolonged activation of heat shock factor-1

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12 December 2020

Caretaker or undertaker? The role of the proteasome in aging

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12 December 2020

The ubiquitin-proteasome system in Creutzfeldt-Jakob and Alzheimer disease: intracellular redistribution of components correlates with neuronal vulnerability.

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12 December 2020

Evolution of myoglobin

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12 December 2020

Review: mechanisms of disaggregation and refolding of stable protein aggregates by molecular chaperones

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12 December 2020

Protein profile of aging and its retardation by caloric restriction in neural retina

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12 December 2020

Major differences in antigen-processing correlate with a single Arg71<-->Lys substitution in HLA-DR molecules predisposing to rheumatoid arthritis and with their selective interactions with 70-kDa heat shock protein chaperones

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12 December 2020

Food restriction, evolution and ageing

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12 December 2020

Protein unfolding in the cell

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12 December 2020

Molecular chaperones in the cytosol: from nascent chain to folded protein

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12 December 2020

The protein import motor of mitochondria

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12 December 2020

Treatment with arimoclomol, a coinducer of heat shock proteins, delays disease progression in ALS mice

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12 December 2020

Geldanamycin induces Hsp70 and prevents alpha-synuclein aggregation and toxicity in vitro

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12 December 2020

Aging and molecular chaperones

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12 December 2020

Polyglutamine aggregates alter protein folding homeostasis in Caenorhabditis elegans

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12 December 2020

Hsp70 chaperones accelerate protein translocation and the unfolding of stable protein aggregates by entropic pulling

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12 December 2020

Effects of heat shock, heat shock protein 40 (HDJ-2), and proteasome inhibition on protein aggregation in cellular models of Huntington's disease

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12 December 2020

Heat shock protein 70 gene polymorphisms in Mexican patients with spondyloarthropathies

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12 December 2020

Controlled expression of recombinant proteins in Physcomitrella patens by a conditional heat-shock promoter: a tool for plant research and biotechnology

1 reference

12 December 2020

Alzheimer's disease: Abeta, tau and synaptic dysfunction

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12 December 2020

Aging reduces responsiveness to BSO- and heat stress-induced perturbations of glutathione and antioxidant enzymes

1 reference

12 December 2020

Induction of HSP70 expression and recruitment of HSC70 and HSP70 in the nucleus reduce aggregation of a polyalanine expansion mutant of PABPN1 in HeLa cells

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12 December 2020

Polyglutamine-expanded androgen receptors form aggregates that sequester heat shock proteins, proteasome components and SRC-1, and are suppressed by the HDJ-2 chaperone

1 reference

12 December 2020

Preferential degradation of oxidized proteins by the 20S proteasome may be inhibited in aging and in inflammatory neuromuscular diseases

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12 December 2020

CHIP suppresses polyglutamine aggregation and toxicity in vitro and in vivo.

1 reference

12 December 2020

Adenoviral transfer of HSP-70 into pulmonary epithelium ameliorates experimental acute respiratory distress syndrome

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12 December 2020

A cell-based assay for aggregation inhibitors as therapeutics of polyglutamine-repeat disease and validation in Drosophila

1 reference

12 December 2020

Evidence for a protein mutator in yeast: role of the Hsp70-related chaperone ssb in formation, stability, and toxicity of the [PSI] prion

1 reference

12 December 2020

From minichaperone to GroEL 2: importance of avidity of the multisite ring structure

1 reference

12 December 2020

Overexpression of yeast hsp104 reduces polyglutamine aggregation and prolongs survival of a transgenic mouse model of Huntington's disease

1 reference

12 December 2020

The Yin and Yang of protein folding

1 reference

12 December 2020

Non-steroidal anti-inflammatory drugs (NSAIDs) in Alzheimer's disease: old and new mechanisms of action

1 reference

12 December 2020

Small heat shock proteins, ClpB and the DnaK system form a functional triade in reversing protein aggregation

1 reference

12 December 2020

The small heat-shock protein IbpB from Escherichia coli stabilizes stress-denatured proteins for subsequent refolding by a multichaperone network

1 reference

12 December 2020

A femtomolar-acting neuroprotective peptide induces increased levels of heat shock protein 60 in rat cortical neurons: a potential neuroprotective mechanism

1 reference

12 December 2020

Alzheimer disease pathology in amyotrophic lateral sclerosis

1 reference

12 December 2020

Protein misfolding, evolution and disease

1 reference

12 December 2020

Therapeutic effects of cystamine in a murine model of Huntington's disease.

1 reference

12 December 2020

Protofibrils, pores, fibrils, and neurodegeneration: separating the responsible protein aggregates from the innocent bystanders

1 reference

12 December 2020

Methods for estimating the case fatality ratio for a novel, emerging infectious disease

1 reference

12 December 2020

Dorfin ubiquitylates mutant SOD1 and prevents mutant SOD1-mediated neurotoxicity

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12 December 2020

Principles that govern the folding of protein chains

1 reference

12 December 2020

The glucose-regulated proteins: stress induction and clinical applications

1 reference

12 December 2020

Curcumin treatment abrogates endoplasmic reticulum retention and aggregation-induced apoptosis associated with neuropathy-causing myelin protein zero-truncating mutants.

1 reference

12 December 2020

Hsp70 promotes TNF-mediated apoptosis by binding IKK gamma and impairing NF-kappa B survival signaling

1 reference

12 December 2020

Identification of thermolabile Escherichia coli proteins: prevention and reversion of aggregation by DnaK and ClpB.

1 reference

12 December 2020

"The stress of dying": the role of heat shock proteins in the regulation of apoptosis

1 reference

12 December 2020

Kinetic partitioning of protein folding and aggregation.

1 reference

12 December 2020

Activity-dependent neurotrophic factor (ADNF). An extracellular neuroprotective chaperonin?

1 reference

12 December 2020

Chaperoning prions: the cellular machinery for propagating an infectious protein?

1 reference

12 December 2020

Alpha-synuclein dysfunction in Lewy body diseases

1 reference

12 December 2020

Tau and alpha-synuclein pathology in amygdala of Parkinsonism-dementia complex patients of Guam

1 reference

12 December 2020

Copper-zinc superoxide dismutase and amyotrophic lateral sclerosis

1 reference

12 December 2020

Heat shock protein 70 participates in the neuroprotective response to intracellularly expressed beta-amyloid in neurons.

1 reference

12 December 2020

Proteasome dysfunction in mammalian aging: steps and factors involved

1 reference

12 December 2020

Progressive disruption of cellular protein folding in models of polyglutamine diseases.

1 reference

12 December 2020

Macromolecular crowding: obvious but underappreciated

1 reference

12 December 2020

Induction of glucose-regulated protein (glucose-regulated protein 78/BiP and glucose-regulated protein 94) and heat shock protein 70 transcripts in the immature rat brain following status epilepticus.

1 reference

12 December 2020

Aggresomes, inclusion bodies and protein aggregation

1 reference

12 December 2020

Heat shock proteins: modifying factors in physiological stress responses and acquired thermotolerance

1 reference

12 December 2020

Hormetic mechanisms of anti-aging and rejuvenating effects of repeated mild heat stress on human fibroblasts in vitro.

1 reference

12 December 2020

Lifespan extension of Drosophila melanogaster through hormesis by repeated mild heat stress.

1 reference

12 December 2020

Chaperones Hsp70 and Hsp40 suppress aggregate formation and apoptosis in cultured neuronal cells expressing truncated androgen receptor protein with expanded polyglutamine tract

1 reference

12 December 2020

Celastrols as inducers of the heat shock response and cytoprotection.

1 reference

12 December 2020

1 reference

12 December 2020

Nonsteroidal anti-inflammatory drugs protect against Parkinson neurodegeneration: can an NSAID a day keep Parkinson disease away?

1 reference

12 December 2020

Reconstitution of active dimeric ribulose bisphosphate carboxylase from an unfoleded state depends on two chaperonin proteins and Mg-ATP.

1 reference

12 December 2020

The fetal basis of amyloidogenesis: exposure to lead and latent overexpression of amyloid precursor protein and beta-amyloid in the aging brain.

1 reference

12 December 2020

1 reference

12 December 2020

Autocatalytic self-propagation of misfolded prion protein

1 reference

12 December 2020

Negative regulation of the Apaf-1 apoptosome by Hsp70

1 reference

12 December 2020

Heat shock proteins and the inflammatory response

1 reference

12 December 2020

Characterization of collapsed states in the early stages of the refolding of hen lysozyme

1 reference

12 December 2020

Pharmacological induction of heat-shock proteins alleviates polyglutamine-mediated motor neuron disease

1 reference

12 December 2020

Early environmental origins of neurodegenerative disease in later life

1 reference

12 December 2020

Hsp90 as a capacitor of phenotypic variation

1 reference

12 December 2020

Inhibition of huntingtin fibrillogenesis by specific antibodies and small molecules: implications for Huntington's disease therapy

1 reference

12 December 2020

Evidence for a lipochaperonin: association of active protein-folding GroESL oligomers with lipids can stabilize membranes under heat shock conditions

1 reference

12 December 2020

Antiproliferative prostaglandins activate heat shock transcription factor

1 reference

12 December 2020

Heat shock protein 27 prevents cellular polyglutamine toxicity and suppresses the increase of reactive oxygen species caused by huntingtin

1 reference

12 December 2020

Proteasome function and pathological proteins in the pathogenesis of Parkinson's disease

1 reference

12 December 2020

Sequential mechanism of solubilization and refolding of stable protein aggregates by a bichaperone network

1 reference

12 December 2020

Parkin protects against the toxicity associated with mutant alpha-synuclein: proteasome dysfunction selectively affects catecholaminergic neurons

1 reference

12 December 2020

Geranylgeranylacetone, a noninvasive heat shock protein inducer, induces protein kinase C and leads to neuroprotection against cerebral infarction in rats

1 reference

12 December 2020

Does proteasome [corrected] inhibition decrease or accelerate toxin-induced dopaminergic neurodegeneration?

1 reference

12 December 2020

The Chaperone Protein BiP Binds to a Mutant Prion Protein and Mediates Its Degradation by the Proteasome

1 reference

12 December 2020

Cecal ligation and double puncture impairs heat shock protein 70 (HSP-70) expression in the lungs of rats.

1 reference

12 December 2020

Geranylgeranylacetone ameliorates ischemic acute renal failure via induction of Hsp70.

1 reference

12 December 2020

Chaperone-assisted folding of newly synthesized proteins in the cytosol

1 reference

12 December 2020

Modulation of prion protein oligomerization, aggregation, and beta-sheet conversion by 4,4'-dianilino-1,1'-binaphthyl-5,5'-sulfonate (bis-ANS).

1 reference

12 December 2020

Induction of heat shock proteins in Chinese hamster ovary cells and development of thermotolerance by intermediate concentrations of puromycin.

1 reference

12 December 2020

To be or not to be (inflamed)--is that the question in anti-inflammatory drug therapy of neurodegenerative disorders?

1 reference

12 December 2020

Chaperone suppression of aggregation and altered subcellular proteasome localization imply protein misfolding in SCA1.

1 reference

12 December 2020

Cracking the folding code. Why do some proteins adopt partially folded conformations, whereas other don't?

1 reference

12 December 2020

Mechanism of regulation of hsp70 chaperones by DnaJ cochaperones

1 reference

12 December 2020

Effect of sodium salicylate on the human heat shock response

1 reference

12 December 2020

Chaperone suppression of alpha-synuclein toxicity in a Drosophila model for Parkinson's disease

1 reference

12 December 2020

HSP70 stimulates cytokine production through a CD14-dependant pathway, demonstrating its dual role as a chaperone and cytokine

1 reference

12 December 2020

Up-regulation of protein chaperones preserves viability of cells expressing toxic Cu/Zn-superoxide dismutase mutants associated with amyotrophic lateral sclerosis

1 reference

12 December 2020

Roles of molecular chaperones in protein misfolding diseases

1 reference

12 December 2020

Role of oxidative stress in neurodegeneration: recent developments in assay methods for oxidative stress and nutraceutical antioxidants

1 reference

12 December 2020

Analysis of the role of heat shock protein (Hsp) molecular chaperones in polyglutamine disease

1 reference

12 December 2020

The ubiquitin proteolytic system: from a vague idea, through basic mechanisms, and onto human diseases and drug targeting

1 reference

12 December 2020

ROS effects on neurodegeneration in Alzheimer's disease and related disorders: on environmental stresses of ionizing radiation

1 reference

12 December 2020

Hsp70 Reduces alpha-Synuclein Aggregation and Toxicity

1 reference

12 December 2020

Type 2 diabetes mellitus as a conformational disease

1 reference

12 December 2020

Myocardial heat shock protein 70 expression in young and old rats after identical exercise programs

1 reference

12 December 2020

The co-chaperone carboxyl terminus of Hsp70-interacting protein (CHIP) mediates alpha-synuclein degradation decisions between proteasomal and lysosomal pathways

1 reference

12 December 2020

Aging and proinflammatory cytokines

1 reference

12 December 2020

Rifampicin inhibits alpha-synuclein fibrillation and disaggregates fibrils

1 reference

12 December 2020

Heat shock response modulators as therapeutic tools for diseases of protein conformation

1 reference

12 December 2020

Endoplasmic reticulum chaperones GRP78 and calreticulin prevent oxidative stress, Ca2+ disturbances, and cell death in renal epithelial cells

1 reference

12 December 2020

Role of the chaperone protein Hsp104 in propagation of the yeast prion-like factor [psi+]

1 reference

12 December 2020

Hsp27 and Hsp70 administered in combination have a potent protective effect against FALS-associated SOD1-mutant-induced cell death in mammalian neuronal cells

1 reference

12 December 2020

Interleukin-1beta-induced fever in young and old Long-Evans rats.

1 reference

12 December 2020

Active solubilization and refolding of stable protein aggregates by cooperative unfolding action of individual hsp70 chaperones

1 reference

12 December 2020

Reversal of a full-length mutant huntingtin neuronal cell phenotype by chemical inhibitors of polyglutamine-mediated aggregation

1 reference

12 December 2020

Inflammatory status as an important determinant of heat shock protein 70 serum concentrations during aging

1 reference

12 December 2020

Modulation of neurodegeneration by molecular chaperones

1 reference

12 December 2020

Progressive decrease in chaperone protein levels in a mouse model of Huntington's disease and induction of stress proteins as a therapeutic approach

1 reference

12 December 2020

Novel signal transduction pathway utilized by extracellular HSP70: role of toll-like receptor (TLR) 2 and TLR4.

1 reference

12 December 2020

Neurodegenerative disease: amyloid pores from pathogenic mutations

1 reference

12 December 2020

Curcumin inhibits formation of amyloid beta oligomers and fibrils, binds plaques, and reduces amyloid in vivo

1 reference

12 December 2020

Calpain and other cytosolic proteases can contribute to the degradation of retro-translocated prion protein in the cytosol

1 reference

12 December 2020

Bimoclomol: a nontoxic, hydroxylamine derivative with stress protein-inducing activity and cytoprotective effects

1 reference

12 December 2020

Resveratrol: preventing properties against vascular alterations and ageing

1 reference

12 December 2020

Altered proteasome structure, function, and oxidation in aged muscle

1 reference

12 December 2020

Synechocystis HSP17 is an amphitropic protein that stabilizes heat-stressed membranes and binds denatured proteins for subsequent chaperone-mediated refolding

1 reference

12 December 2020

Continuous enhanced expression of Hsc70 but not Hsp70 in rheumatoid arthritis synovial tissue

1 reference

12 December 2020

Rescuing protein conformation: prospects for pharmacological therapy in cystic fibrosis

1 reference

12 December 2020

Protein folding revisited. A polypeptide chain at the folding ? misfolding ? nonfolding cross-roads: which way to go?

1 reference

12 December 2020