(Q36783160)

16 August 2017

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title

Epigenetics and microRNAs (English)

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16 August 2017

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Pål Saetrom

1

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16 August 2017

Ola Snøve

series ordinal

2

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16 August 2017

John J Rossi

series ordinal

3

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16 August 2017

language of work or name

English

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publication date

1 May 2007

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16 August 2017

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16 August 2017

volume

61

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16 August 2017

issue

5 Pt 2

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16 August 2017

page(s)

17R-23R

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Unlocking the potential of the human genome with RNA interference

16 August 2017

cites work

1 reference

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Identification of novel genes coding for small expressed RNAs

21 January 2018

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An abundant class of tiny RNAs with probable regulatory roles in Caenorhabditis elegans

21 January 2018

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An extensive class of small RNAs in Caenorhabditis elegans

21 January 2018

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DNA methylation patterns and epigenetic memory

21 January 2018

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Translating the Histone Code

21 January 2018

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Chromatin modification and epigenetic reprogramming in mammalian development

21 January 2018

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DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development

21 January 2018

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Methylation of tRNAAsp by the DNA methyltransferase homolog Dnmt2

21 January 2018

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Crystal structure of the nucleosome core particle at 2.8 A resolution

21 January 2018

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RNA-mediated non-mendelian inheritance of an epigenetic change in the mouse

21 January 2018

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The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14

21 January 2018

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The lin-4 regulatory RNA controls developmental timing in Caenorhabditis elegans by blocking LIN-14 protein synthesis after the initiation of translation

21 January 2018

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The 21-nucleotide let-7 RNA regulates developmental timing in Caenorhabditis elegans

21 January 2018

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Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegans

21 January 2018

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miRBase: microRNA sequences, targets and gene nomenclature

21 January 2018

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Identification of hundreds of conserved and nonconserved human microRNAs

21 January 2018

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https://api.crossref.org/works/10.1203%2FPDR.0B013E318045760E

Many novel mammalian microRNA candidates identified by extensive cloning and RAKE analysis

21 January 2018

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https://api.crossref.org/works/10.1203%2FPDR.0B013E318045760E

Phylogenetic shadowing and computational identification of human microRNA genes

21 January 2018

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https://api.crossref.org/works/10.1203%2FPDR.0B013E318045760E

Differences in vertebrate microRNA expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1203%2FPDR.0B013E318045760E

Human microRNAs are processed from capped, polyadenylated transcripts that can also function as mRNAs

21 January 2018

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https://api.crossref.org/works/10.1203%2FPDR.0B013E318045760E

MicroRNA genes are transcribed by RNA polymerase II

21 January 2018

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https://api.crossref.org/works/10.1203%2FPDR.0B013E318045760E

New microRNAs from mouse and human

21 January 2018

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https://api.crossref.org/works/10.1203%2FPDR.0B013E318045760E

The UCSC Genome Browser Database

21 January 2018

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https://api.crossref.org/works/10.1203%2FPDR.0B013E318045760E

Clustering and conservation patterns of human microRNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1203%2FPDR.0B013E318045760E

Microarray profiling of microRNAs reveals frequent coexpression with neighboring miRNAs and host genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1203%2FPDR.0B013E318045760E

Processing of primary microRNAs by the Microprocessor complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1203%2FPDR.0B013E318045760E

The Microprocessor complex mediates the genesis of microRNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1203%2FPDR.0B013E318045760E

The Drosha-DGCR8 complex in primary microRNA processing

21 January 2018

1 reference

https://api.crossref.org/works/10.1203%2FPDR.0B013E318045760E

The nuclear RNase III Drosha initiates microRNA processing

21 January 2018

1 reference

https://api.crossref.org/works/10.1203%2FPDR.0B013E318045760E

Molecular basis for the recognition of primary microRNAs by the Drosha-DGCR8 complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1203%2FPDR.0B013E318045760E

Conserved microRNA characteristics in mammals

21 January 2018

1 reference

https://api.crossref.org/works/10.1203%2FPDR.0B013E318045760E

Recognition and cleavage of primary microRNA precursors by the nuclear processing enzyme Drosha

21 January 2018

1 reference

https://api.crossref.org/works/10.1203%2FPDR.0B013E318045760E

Exportin 5 is a RanGTP-dependent dsRNA-binding protein that mediates nuclear export of pre-miRNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1203%2FPDR.0B013E318045760E

Nuclear export of microRNA precursors

21 January 2018

1 reference

https://api.crossref.org/works/10.1203%2FPDR.0B013E318045760E

Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1203%2FPDR.0B013E318045760E

Structural requirements for pre-microRNA binding and nuclear export by Exportin 5.

21 January 2018

1 reference

https://api.crossref.org/works/10.1203%2FPDR.0B013E318045760E

Fatality in mice due to oversaturation of cellular microRNA/short hairpin RNA pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1203%2FPDR.0B013E318045760E

Overexpression of exportin 5 enhances RNA interference mediated by short hairpin RNAs and microRNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1203%2FPDR.0B013E318045760E

Role for a bidentate ribonuclease in the initiation step of RNA interference

21 January 2018

1 reference

https://api.crossref.org/works/10.1203%2FPDR.0B013E318045760E

A cellular function for the RNA-interference enzyme Dicer in the maturation of the let-7 small temporal RNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1203%2FPDR.0B013E318045760E

The contributions of dsRNA structure to Dicer specificity and efficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1203%2FPDR.0B013E318045760E

TRBP recruits the Dicer complex to Ago2 for microRNA processing and gene silencing

21 January 2018

1 reference

https://api.crossref.org/works/10.1203%2FPDR.0B013E318045760E

Human RISC couples microRNA biogenesis and posttranscriptional gene silencing

21 January 2018

1 reference

https://api.crossref.org/works/10.1203%2FPDR.0B013E318045760E

Passenger-strand cleavage facilitates assembly of siRNA into Ago2-containing RNAi enzyme complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1203%2FPDR.0B013E318045760E

Argonaute2 cleaves the anti-guide strand of siRNA during RISC activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1203%2FPDR.0B013E318045760E

A protein sensor for siRNA asymmetry

21 January 2018

1 reference

https://api.crossref.org/works/10.1203%2FPDR.0B013E318045760E

Functional siRNAs and miRNAs Exhibit Strand Bias

21 January 2018

1 reference

https://api.crossref.org/works/10.1203%2FPDR.0B013E318045760E

Asymmetry in the assembly of the RNAi enzyme complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1203%2FPDR.0B013E318045760E

Post-transcriptional regulation of microRNA expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1203%2FPDR.0B013E318045760E

Extensive post-transcriptional regulation of microRNAs and its implications for cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1203%2FPDR.0B013E318045760E

Structural basis for 5'-end-specific recognition of guide RNA by the A. fulgidus Piwi protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1203%2FPDR.0B013E318045760E

Structural insights into mRNA recognition from a PIWI domain-siRNA guide complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1203%2FPDR.0B013E318045760E

Purified Argonaute2 and an siRNA form recombinant human RISC

21 January 2018

1 reference

https://api.crossref.org/works/10.1203%2FPDR.0B013E318045760E

MicroRNA-directed cleavage of HOXB8 mRNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1203%2FPDR.0B013E318045760E

RNAi: double-stranded RNA directs the ATP-dependent cleavage of mRNA at 21 to 23 nucleotide intervals

21 January 2018

1 reference

https://api.crossref.org/works/10.1203%2FPDR.0B013E318045760E

Regulation by let-7 and lin-4 miRNAs results in target mRNA degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1203%2FPDR.0B013E318045760E

MicroRNAs regulate brain morphogenesis in zebrafish

21 January 2018

1 reference

https://api.crossref.org/works/10.1203%2FPDR.0B013E318045760E

MicroRNAs direct rapid deadenylation of mRNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1203%2FPDR.0B013E318045760E

Tolerance for mutations and chemical modifications in a siRNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1203%2FPDR.0B013E318045760E

A systematic analysis of the silencing effects of an active siRNA at all single-nucleotide mismatched target sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1203%2FPDR.0B013E318045760E

Functional anatomy of siRNAs for mediating efficient RNAi in Drosophila melanogaster embryo lysate

21 January 2018

1 reference

https://api.crossref.org/works/10.1203%2FPDR.0B013E318045760E

Designing siRNA that distinguish between genes that differ by a single nucleotide

21 January 2018

1 reference

https://api.crossref.org/works/10.1203%2FPDR.0B013E318045760E

Principles of microRNA-target recognition

21 January 2018

1 reference

https://api.crossref.org/works/10.1203%2FPDR.0B013E318045760E

Combinatorial microRNA target predictions

21 January 2018

1 reference

https://api.crossref.org/works/10.1203%2FPDR.0B013E318045760E

Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets

21 January 2018

1 reference

https://api.crossref.org/works/10.1203%2FPDR.0B013E318045760E

Prediction of mammalian microRNA targets

21 January 2018

1 reference

https://api.crossref.org/works/10.1203%2FPDR.0B013E318045760E

Systematic discovery of regulatory motifs in human promoters and 3' UTRs by comparison of several mammals

21 January 2018

1 reference

https://api.crossref.org/works/10.1203%2FPDR.0B013E318045760E

Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1203%2FPDR.0B013E318045760E

The C. elegans microRNA let-7 binds to imperfect let-7 complementary sites from the lin-41 3'UTR

21 January 2018

1 reference

https://api.crossref.org/works/10.1203%2FPDR.0B013E318045760E

Architecture of a validated microRNA::target interaction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1203%2FPDR.0B013E318045760E

Identification and characterization of small RNAs involved in RNA silencing

21 January 2018

1 reference

https://api.crossref.org/works/10.1203%2FPDR.0B013E318045760E

MicroRNAs: genomics, biogenesis, mechanism, and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1203%2FPDR.0B013E318045760E

microPrimer: the biogenesis and function of microRNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1203%2FPDR.0B013E318045760E

Functions of microRNAs and related small RNAs in plants

21 January 2018

1 reference

https://api.crossref.org/works/10.1203%2FPDR.0B013E318045760E

Arabidopsis micro-RNA biogenesis through Dicer-like 1 protein functions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1203%2FPDR.0B013E318045760E

Methylation as a crucial step in plant microRNA biogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1203%2FPDR.0B013E318045760E

Prediction of plant microRNA targets

21 January 2018

1 reference

https://api.crossref.org/works/10.1203%2FPDR.0B013E318045760E

MicroRNA binding sites in Arabidopsis class III HD-ZIP mRNAs are required for methylation of the template chromosome

21 January 2018

1 reference

https://api.crossref.org/works/10.1203%2FPDR.0B013E318045760E

siRNAs can function as miRNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1203%2FPDR.0B013E318045760E

On the art of identifying effective and specific siRNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1203%2FPDR.0B013E318045760E

A comparison of siRNA efficacy predictors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1203%2FPDR.0B013E318045760E

Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1203%2FPDR.0B013E318045760E

Synthetic dsRNA Dicer substrates enhance RNAi potency and efficacy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1203%2FPDR.0B013E318045760E

Synthetic shRNAs as potent RNAi triggers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1203%2FPDR.0B013E318045760E

Lessons from Nature: microRNA-based shRNA libraries

21 January 2018

1 reference

https://api.crossref.org/works/10.1203%2FPDR.0B013E318045760E

Gene silencing using micro-RNA designed hairpins

21 January 2018

1 reference

https://api.crossref.org/works/10.1203%2FPDR.0B013E318045760E

Short hairpin RNAs (shRNAs) induce sequence-specific silencing in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1203%2FPDR.0B013E318045760E

The role of RNA interference in heterochromatic silencing

21 January 2018

1 reference

https://api.crossref.org/works/10.1203%2FPDR.0B013E318045760E

Specific association of Piwi with rasiRNAs derived from retrotransposon and heterochromatic regions in the Drosophila genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1203%2FPDR.0B013E318045760E

A distinct small RNA pathway silences selfish genetic elements in the germline

21 January 2018

1 reference

https://api.crossref.org/works/10.1203%2FPDR.0B013E318045760E

Identification and characterization of two novel classes of small RNAs in the mouse germline: retrotransposon-derived siRNAs in oocytes and germline small RNAs in testes

21 January 2018

1 reference

https://api.crossref.org/works/10.1203%2FPDR.0B013E318045760E

microRNA-directed phasing during trans-acting siRNA biogenesis in plants

21 January 2018

1 reference

https://api.crossref.org/works/10.1203%2FPDR.0B013E318045760E

Endogenous siRNAs derived from a pair of natural cis-antisense transcripts regulate salt tolerance in Arabidopsis

21 January 2018

1 reference

https://api.crossref.org/works/10.1203%2FPDR.0B013E318045760E

A novel class of small RNAs in mouse spermatogenic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1203%2FPDR.0B013E318045760E

Characterization of the piRNA Complex from Rat Testes

21 January 2018

1 reference

https://api.crossref.org/works/10.1203%2FPDR.0B013E318045760E

The functions of animal microRNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1203%2FPDR.0B013E318045760E

MicroRNA expression in zebrafish embryonic development

21 January 2018

1 reference

https://api.crossref.org/works/10.1203%2FPDR.0B013E318045760E

Heavy de novo methylation at symmetrical and non-symmetrical sites is a hallmark of RNA-directed DNA methylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1203%2FPDR.0B013E318045760E

RNA-directed de novo methylation of genomic sequences in plants.

21 January 2018

1 reference

https://api.crossref.org/works/10.1203%2FPDR.0B013E318045760E

Small interfering RNA-induced transcriptional gene silencing in human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1203%2FPDR.0B013E318045760E

Short double-stranded RNA induces transcriptional gene silencing in human cancer cells in the absence of DNA methylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1203%2FPDR.0B013E318045760E

Argonaute-1 directs siRNA-mediated transcriptional gene silencing in human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1203%2FPDR.0B013E318045760E

Involvement of AGO1 and AGO2 in mammalian transcriptional silencing

21 January 2018

1 reference

https://api.crossref.org/works/10.1203%2FPDR.0B013E318045760E

On the role of RNA amplification in dsRNA-triggered gene silencing

21 January 2018

1 reference

https://api.crossref.org/works/10.1203%2FPDR.0B013E318045760E

An RNA-dependent RNA polymerase gene in Arabidopsis is required for posttranscriptional gene silencing mediated by a transgene but not by a virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1203%2FPDR.0B013E318045760E

Analysis of gene function in somatic mammalian cells using small interfering RNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1203%2FPDR.0B013E318045760E

Genetic requirements for inheritance of RNAi in C. elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1203%2FPDR.0B013E318045760E

Epigenetics in human disease and prospects for epigenetic therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1203%2FPDR.0B013E318045760E

Oncomirs - microRNAs with a role in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1203%2FPDR.0B013E318045760E

Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1203%2FPDR.0B013E318045760E

Frequent deletions and down-regulation of micro- RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1203%2FPDR.0B013E318045760E

Accumulation of miR-155 and BIC RNA in human B cell lymphomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1203%2FPDR.0B013E318045760E

A microRNA polycistron as a potential human oncogene

21 January 2018

1 reference

https://api.crossref.org/works/10.1203%2FPDR.0B013E318045760E

c-Myc-regulated microRNAs modulate E2F1 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1203%2FPDR.0B013E318045760E

Progress towards in vivo use of siRNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1203%2FPDR.0B013E318045760E

Activation of the mammalian immune system by siRNAs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1203%2FPDR.0B013E318045760E

Activation of the interferon system by short-interfering RNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1203%2FPDR.0B013E318045760E

3' UTR seed matches, but not overall identity, are associated with RNAi off-targets

21 January 2018

1 reference

https://api.crossref.org/works/10.1203%2FPDR.0B013E318045760E

Off-target effects by siRNA can induce toxic phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1203%2FPDR.0B013E318045760E

Expression profiling reveals off-target gene regulation by RNAi

21 January 2018

1 reference

https://api.crossref.org/works/10.1203%2FPDR.0B013E318045760E

Widespread siRNA "off-target" transcript silencing mediated by seed region sequence complementarity

21 January 2018

1 reference

https://api.crossref.org/works/10.1203%2FPDR.0B013E318045760E

siRNA-mediated off-target gene silencing triggered by a 7 nt complementation

21 January 2018

1 reference

https://api.crossref.org/works/10.1203%2FPDR.0B013E318045760E

Therapeutic silencing of an endogenous gene by systemic administration of modified siRNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1203%2FPDR.0B013E318045760E

RNAi-mediated gene silencing in non-human primates.

21 January 2018

1 reference

https://api.crossref.org/works/10.1203%2FPDR.0B013E318045760E

MicroRNA expression profiles classify human cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1203%2FPDR.0B013E318045760E

Mammalian microRNAs derived from genomic repeats

21 January 2018

1 reference

https://api.crossref.org/works/10.1203%2FPDR.0B013E318045760E

Induction of an interferon response by RNAi vectors in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1203%2FPDR.0B013E318045760E

10.1203/PDR.0B013E318045760E

21 January 2018

Identifiers

DOI

1 reference

Dimensions Publication ID

16 August 2017

1033634259

0 references

1 reference