(Q36798931)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17452246%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

review article

1 reference

title

Involvement of homologous recombination in carcinogenesis (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17452246%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

1 reference

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17452246%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

author name string

Ramune Reliene

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17452246%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

Robert H Schiestl

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17452246%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

publication date

1 January 2007

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17452246%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17452246%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

volume

58

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17452246%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

page(s)

67-87

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17452246%20AND%20SRC:MED&resulttype=core&format=json

The RAD51 protein supports homologous recombination by an exchange mechanism in mammalian cells

29 December 2019

cites work

1 reference

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7 January 2021

Carcinogens induce intrachromosomal recombination in human cells

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7 January 2021

Involvement of p53 in X-ray induced intrachromosomal recombination in mice

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7 January 2021

Two families of low-copy-number repeats are interspersed on Xp22.3: Implications for the high frequency of deletions in this region

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7 January 2021

Loss of the ataxia-telangiectasia gene product causes oxidative damage in target organs.

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7 January 2021

Increase of spontaneous intrachromosomal homologous recombination in mammalian cells expressing a mutant p53 protein

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7 January 2021

Benzo(a)pyrene and X-rays induce reversions of the pink-eyed unstable mutation in the retinal pigment epithelium of mice

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7 January 2021

p21 controls patterning but not homologous recombination in RPE development.

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7 January 2021

Cadmium is an inducer of oxidative stress in yeast.

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7 January 2021

Aniline and its metabolites generate free radicals in yeast.

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7 January 2021

Diaminotoluenes induce intrachromosomal recombination and free radicals in Saccharomyces cerevisiae.

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7 January 2021

Chloroform and carbon tetrachloride induce intrachromosomal recombination and oxidative free radicals in Saccharomyces cerevisiae

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7 January 2021

Free radicals generated in yeast by the Salmonella test-negative carcinogens benzene, urethane, thiourea and auramine O.

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7 January 2021

The aromatic amine carcinogens o-toluidine and o-anisidine induce free radicals and intrachromosomal recombination in Saccharomyces cerevisiae

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7 January 2021

Interaction of p53 with the human Rad51 protein

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7 January 2021

Genome instability in a region of human DNA enriched in Alu repeat sequences

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7 January 2021

Evaluation of the yeast DEL assay with 10 compounds selected by the International Program on Chemical Safety for the evaluation of short-term tests for carcinogens.

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7 January 2021

Drug sensitivity spectra in Fanconi anemia lymphoblastoid cell lines of defined complementation groups

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7 January 2021

The Mre11 complex is required for ATM activation and the G2/M checkpoint

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7 January 2021

DNA deletion associated with hereditary neuropathy with liability to pressure palsies

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7 January 2021

Werner's syndrome protein (WRN) migrates Holliday junctions and co-localizes with RPA upon replication arrest

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7 January 2021

Xrcc2 is required for genetic stability, embryonic neurogenesis and viability in mice

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7 January 2021

A deletion in chromosome 22 can cause DiGeorge syndrome

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7 January 2021

Attenuation of the formation of DNA-repair foci containing RAD51 in Fanconi anaemia

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7 January 2021

Deficient Regulation of DNA Double-strand Break Repair in Fanconi Anemia Fibroblasts

1 reference

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7 January 2021

The Bloom's syndrome gene product is homologous to RecQ helicases

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2806%2958003-4

7 January 2021

Effects of Salmonella assay negative and positive carcinogens on intrachromosomal recombination in G1-arrested yeast cells.

1 reference

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7 January 2021

Cell division transforms mutagenic lesions into deletion-recombinagenic lesions in yeast cells

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7 January 2021

Interaction of the Fanconi anemia proteins and BRCA1 in a common pathway

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7 January 2021

Homologous and nonhomologous recombination resulting in deletion: effects of p53 status, microhomology, and repetitive DNA length and orientation

1 reference

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7 January 2021

https://api.crossref.org/works/10.1016%2FS0065-2660%2806%2958003-4

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7 January 2021

Partners and pathwaysrepairing a double-strand break.

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7 January 2021

Homologous recombination and cell cycle checkpoints: Rad51 in tumour progression and therapy resistance

1 reference

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7 January 2021

Mechanisms and consequences of replication fork arrest.

1 reference

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7 January 2021

Werner and Bloom helicases are involved in DNA repair in a complementary fashion

1 reference

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7 January 2021

Sensing and repairing DNA double-strand breaks

1 reference

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7 January 2021

Structure of chromosomal duplicons and their role in mediating human genomic disorders

1 reference

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7 January 2021

The emerging genetic and molecular basis of Fanconi anaemia

1 reference

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7 January 2021

The Bloom's syndrome gene product promotes branch migration of holliday junctions

1 reference

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7 January 2021

Overexpression of human RAD51 and RAD52 reduces double-strand break-induced homologous recombination in mammalian cells

1 reference

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7 January 2021

Antioncogenes and human cancer

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7 January 2021

Two genetic hits (more or less) to cancer

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7 January 2021

The cytogenetics of ataxia telangiectasia

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7 January 2021

Brca2 (XRCC11) deficiency results in radioresistant DNA synthesis and a higher frequency of spontaneous deletions

1 reference

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7 January 2021

Recombination proteins in yeast

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7 January 2021

DNA replication meets genetic exchange: chromosomal damage and its repair by homologous recombination

1 reference

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7 January 2021

The genetic defect in ataxia-telangiectasia

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7 January 2021

Increased frequency of DNA deletions in pink-eyed unstable mice carrying a mutation in the Werner syndrome gene homologue

1 reference

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7 January 2021

Deletions of chromosome 15 as a cause of the Prader-Willi syndrome

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7 January 2021

Mutation in LDL receptor: Alu-Alu recombination deletes exons encoding transmembrane and cytoplasmic domains

1 reference

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7 January 2021

Genetic instabilities in human cancers

1 reference

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7 January 2021

p53, the cellular gatekeeper for growth and division

1 reference

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7 January 2021

Soft-tissue sarcomas, breast cancer, and other neoplasms. A familial syndrome?

1 reference

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7 January 2021

A mutation in mouse rad51 results in an early embryonic lethal that is suppressed by a mutation in p53

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2806%2958003-4

7 January 2021

Altered cell cycle arrest and gene amplification potential accompany loss of wild-type p53

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2806%2958003-4

7 January 2021

Significance of multiple mutations in cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2806%2958003-4

7 January 2021

Genomic disorders: structural features of the genome can lead to DNA rearrangements and human disease traits

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2806%2958003-4

7 January 2021

Over-expression of wild-type Rad51 correlates with histological grading of invasive ductal breast cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2806%2958003-4

7 January 2021

DNA repair and recombination factor Rad51 is over-expressed in human pancreatic adenocarcinoma

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2806%2958003-4

7 January 2021

Tumor suppressor genes

1 reference

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7 January 2021

The BRCA2 gene product functionally interacts with p53 and RAD51

1 reference

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7 January 2021

Pathological consequences of sequence duplications in the human genome

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7 January 2021

Inactivation of p53 results in high rates of homologous recombination

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2806%2958003-4

7 January 2021

Ataxia-telangiectasia, cancer and the pathobiology of the ATM gene

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2806%2958003-4

7 January 2021

BRCA2 is required for homology-directed repair of chromosomal breaks

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2806%2958003-4

7 January 2021

Human Fanconi anemia monoubiquitination pathway promotes homologous DNA repair

1 reference

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7 January 2021

Breast cancer genetics: what we know and what we need

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7 January 2021

Characteristic mRNA abnormality found in half the patients with severe haemophilia A is due to large DNA inversions

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7 January 2021

Estimation of the mutation frequencies in Charcot-Marie-Tooth disease type 1 and hereditary neuropathy with liability to pressure palsies: a European collaborative study

1 reference

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7 January 2021

Charcot-Marie-Tooth type 1A duplication appears to arise from recombination at repeat sequences flanking the 1.5 Mb monomer unit

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7 January 2021

NHEJ deficiency and disease

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7 January 2021

Midgestation lethality in mice deficient for the RecA-related gene, Rad51d/Rad51l3.

1 reference

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7 January 2021

Recombination hot spots and human disease

1 reference

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7 January 2021

A potential role for the XRCC2 R188H polymorphic site in DNA-damage repair and breast cancer

1 reference

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7 January 2021

Anti-oxidative capacity in patients with ataxia telangiectasia

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2806%2958003-4

7 January 2021

Elevated oxidative stress in patients with ataxia telangiectasia

1 reference

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7 January 2021

Mouse models for induced genetic instability at endogenous loci

1 reference

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7 January 2021

Effect of N-acetyl cysteine on oxidative DNA damage and the frequency of DNA deletions in atm-deficient mice

1 reference

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7 January 2021

Diesel exhaust particles cause increased levels of DNA deletions after transplacental exposure in mice

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2806%2958003-4

7 January 2021

Rad51 overexpression promotes alternative double-strand break repair pathways and genome instability

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2806%2958003-4

7 January 2021

The variant E233G of the RAD51D gene could be a low-penetrance allele in high-risk breast cancer families without BRCA1/2 mutations

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2806%2958003-4

7 January 2021

Carcinogens induce intrachromosomal recombination in yeast.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2806%2958003-4

7 January 2021

Safrole, eugenol and methyleugenol induce intrachromosomal recombination in yeast.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2806%2958003-4

7 January 2021

Reversion of the mouse pink-eyed unstable mutation induced by low doses of x-rays.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2806%2958003-4

7 January 2021

Carcinogens induce reversion of the mouse pink-eyed unstable mutation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2806%2958003-4

7 January 2021

In search of the tumour-suppressor functions of BRCA1 and BRCA2

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2806%2958003-4

7 January 2021

Unwinding the molecular basis of the Werner syndrome

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7 January 2021

DNA recombination, chromosomal stability and carcinogenesis: insights into the role of BRCA2.

1 reference

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7 January 2021

Disruption of muREC2/RAD51L1 in mice results in early embryonic lethality which can Be partially rescued in a p53(-/-) background

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2806%2958003-4

7 January 2021

BRCA1 deficient embryonic stem cells display a decreased homologous recombination frequency and an increased frequency of non-homologous recombination that is corrected by expression of a brca1 transgene.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2806%2958003-4

7 January 2021

The Li-Fraumeni syndrome: from clinical epidemiology to molecular genetics

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2806%2958003-4

7 January 2021

High frequency of spontaneous translocations revealed by FISH in cells from patients with the cancer-prone syndromes ataxia telangiectasia and Nijmegen breakage syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2806%2958003-4

7 January 2021

p53 is linked directly to homologous recombination processes via RAD51/RecA protein interaction

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2806%2958003-4

7 January 2021

S-phase-specific interaction of the Fanconi anemia protein, FANCD2, with BRCA1 and RAD51

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2806%2958003-4

7 January 2021

The RAD51 gene family, genetic instability and cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2806%2958003-4

7 January 2021

Homologous recombinational repair of DNA ensures mammalian chromosome stability

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2806%2958003-4

7 January 2021

Recombinational DNA repair and human disease

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2806%2958003-4

7 January 2021

How Fanconi anemia proteins promote the four Rs: replication, recombination, repair, and recovery

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2806%2958003-4

7 January 2021

Targeted disruption of the Rad51 gene leads to lethality in embryonic mice

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2806%2958003-4

7 January 2021

Requirement of the MRN complex for ATM activation by DNA damage

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2806%2958003-4

7 January 2021

Chromosome stability, DNA recombination and the BRCA2 tumour suppressor

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2806%2958003-4

7 January 2021

Overexpression of Rad51 protein stimulates homologous recombination and increases resistance of mammalian cells to ionizing radiation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2806%2958003-4

7 January 2021

Possible association of BLM in decreasing DNA double strand breaks during DNA replication

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2806%2958003-4

7 January 2021

Functional interaction of p53 and BLM DNA helicase in apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2806%2958003-4

7 January 2021

Loss of heterozygosity in somatic cells of the mouse. An important step in cancer initiation?

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2806%2958003-4

7 January 2021

RAD51 interacts with the evolutionarily conserved BRC motifs in the human breast cancer susceptibility gene brca2

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2806%2958003-4

7 January 2021

Potential role for the BLM helicase in recombinational repair via a conserved interaction with RAD51

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2806%2958003-4

7 January 2021

Centrosome amplification and a defective G2-M cell cycle checkpoint induce genetic instability in BRCA1 exon 11 isoform-deficient cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2806%2958003-4

7 January 2021

Frequent deletions of the human X chromosome distal short arm result from recombination between low copy repetitive elements

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2806%2958003-4

7 January 2021

Wild-type p53 restores cell cycle control and inhibits gene amplification in cells with mutant p53 alleles.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2806%2958003-4

7 January 2021

Abnormal expression of BRCA1 and BRCA1-interactive DNA-repair proteins in breast carcinomas

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2806%2958003-4

7 January 2021

BRCA1 physically associates with p53 and stimulates its transcriptional activity.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2806%2958003-4

7 January 2021

Repeat expansion by homologous recombination in the mouse germ line at palindromic sequences

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2806%2958003-4

7 January 2021

The cellular basis of tumor progression

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2806%2958003-4

7 January 2021

10.1016/S0065-2660(06)58003-4

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17452246%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

1 reference