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Imbalance of p75(NTR)/TrkB protein expression in Huntington's disease: implication for neuroprotective therapies.
scientific article published on 18 April 2013
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3641339
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29 February 2020
title
Imbalance of p75(NTR)/TrkB protein expression in Huntington's disease: implication for neuroprotective therapies
(English)
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PMC publication ID
3641339
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29 February 2020
main subject
Huntington's disease
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Verónica Brito
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1
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Europe PubMed Central
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3641339
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29 February 2020
Albert Giralt
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3
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29 February 2020
Daniel del Toro
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4
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29 February 2020
Jordi Alberch
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5
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29 February 2020
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M Puigdellívol
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2
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29 February 2020
S Ginés
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6
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29 February 2020
publication date
18 April 2013
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29 February 2020
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Cell Death and Disease
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29 February 2020
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4
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29 February 2020
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29 February 2020
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The p75NTR intracellular domain generated by neurotrophin-induced receptor cleavage potentiates Trk signaling.
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Brain-derived neurotrophic factor binding to the p75 neurotrophin receptor reduces TrkA signaling while increasing serine phosphorylation in the TrkA intracellular domain.
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The alpha component of the CNTF receptor is required for signaling and defines potential CNTF targets in the adult and during development
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Neurotrophins induce death of hippocampal neurons via the p75 receptor
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Identifiers
DOI
10.1038/CDDIS.2013.116
1 reference
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Europe PubMed Central
PMC publication ID
3641339
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23598407%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 February 2020
PMC publication ID
3641339
1 reference
stated in
Europe PubMed Central
PMC publication ID
3641339
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23598407%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 February 2020
PubMed publication ID
23598407
1 reference
stated in
Europe PubMed Central
PMC publication ID
3641339
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23598407%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 February 2020
ResearchGate publication ID
236227596
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