(Q36825729)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17510910%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

review article

1 reference

title

Transcriptional malfunctioning of heat shock protein gene expression in spinocerebellar ataxias (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17510910%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17510910%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

Chan, H.Y.E.

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17510910%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

author name string

N Y Macy Huen

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17510910%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

publication date

1 January 2007

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17510910%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17510910%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

volume

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17510910%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

issue

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17510910%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

page(s)

111-117

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17510910%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1080/14734220600996480

30 December 2019

exact match

0 references

cites work

Mutant huntingtin alters MAPK signaling pathways in PC12 and striatal cells: ERK1/2 protects against mutant huntingtin-associated toxicity.

1 reference

12 December 2020

Role of the heat shock response and molecular chaperones in oncogenesis and cell death

1 reference

12 December 2020

Spinocerebellar Ataxias

1 reference

12 December 2020

Geldanamycin activates a heat shock response and inhibits huntingtin aggregation in a cell culture model of Huntington's disease

1 reference

12 December 2020

Polyglutamine expansion induces a protein-damaging stress connecting heat shock protein 70 to the JNK pathway

1 reference

12 December 2020

Chaperone suppression of aggregation and altered subcellular proteasome localization imply protein misfolding in SCA1.

1 reference

12 December 2020

Something about SUMO inhibits transcription

1 reference

12 December 2020

Treatment with extracellular HSP70/HSC70 protein can reduce polyglutamine toxicity and aggregation

1 reference

12 December 2020

CHIP protects from the neurotoxicity of expanded and wild-type ataxin-1 and promotes their ubiquitination and degradation

1 reference

12 December 2020

Hyperthermia induces gene expression of heat shock protein 70 and phosphorylation of mitogen activated protein kinases in the rat cerebellum.

1 reference

12 December 2020

JNK mediates pathogenic effects of polyglutamine-expanded androgen receptor on fast axonal transport

1 reference

12 December 2020

Microarrays and polyglutamine disorders: reports from the Hereditary Disease Array Group

1 reference

12 December 2020

Dynamic expression of Hsp27 in the presence of mutant ataxin-3.

1 reference

12 December 2020

Heat shock protein 70 and the acute respiratory distress syndrome

1 reference

12 December 2020

Over-expression of inducible HSP70 chaperone suppresses neuropathology and improves motor function in SCA1 mice

1 reference

12 December 2020

Role of molecular chaperones in neurodegenerative disorders

1 reference

12 December 2020

Glutamine repeats and neurodegeneration

1 reference

12 December 2020

On mechanisms that control heat shock transcription factor activity in metazoan cells

1 reference

12 December 2020

Insoluble TATA-binding protein accumulation in Huntington's disease cortex.

1 reference

12 December 2020

Polyglutamine diseases: a transcription disorder?

1 reference

12 December 2020

Regulation of the heat shock transcriptional response: cross talk between a family of heat shock factors, molecular chaperones, and negative regulators

1 reference

12 December 2020

PDSM, a motif for phosphorylation-dependent SUMO modification

1 reference

12 December 2020

Progressive retinal degeneration and dysfunction in R6 Huntington's disease mice

1 reference

12 December 2020

Polyglutamine protein aggregates are dynamic

1 reference

12 December 2020

In vivo heat-shock response in the brain: signalling pathway and transcription factor activation.

1 reference

12 December 2020

Polyglutamine protein aggregation and toxicity are linked to the cellular stress response

1 reference

12 December 2020

Modification of proteins by ubiquitin and ubiquitin-like proteins

1 reference

12 December 2020

Co-chaperone CHIP associates with expanded polyglutamine protein and promotes their degradation by proteasomes.

1 reference

12 December 2020

Molecular chaperones and protein quality control

1 reference

12 December 2020

Inhibition of DNA binding by differential sumoylation of heat shock factors

1 reference

12 December 2020

Expanded polyglutamine protein forms nuclear inclusions and causes neural degeneration in Drosophila

1 reference

12 December 2020

Pharmacological induction of heat-shock proteins alleviates polyglutamine-mediated motor neuron disease

1 reference

12 December 2020

Hsp70 and hsp40 chaperones can inhibit self-assembly of polyglutamine proteins into amyloid-like fibrils

1 reference

12 December 2020

Regulation of heat shock gene transcription in neuronal cells

1 reference

12 December 2020

Role of heat shock proteins during polyglutamine neurodegeneration: mechanisms and hypothesis

1 reference

12 December 2020

Neuroscience. SUMO wrestles the synapse.

1 reference

12 December 2020

Protein aggregation and neurodegenerative disease

1 reference

12 December 2020

JNK phosphorylates the HSF1 transcriptional activation domain: role of JNK in the regulation of the heat shock response

1 reference

12 December 2020

Chaperoning brain degeneration

1 reference

12 December 2020

Molecular chaperones in cellular protein folding

1 reference

12 December 2020

Drug discovery in the ubiquitin-proteasome system.

1 reference

12 December 2020

Sumo-1 modification regulates the DNA binding activity of heat shock transcription factor 2, a promyelocytic leukemia nuclear body associated transcription factor

1 reference

12 December 2020

Expression of polyglutamine-expanded Huntingtin activates the SEK1-JNK pathway and induces apoptosis in a hippocampal neuronal cell line

1 reference

12 December 2020

Polyglutamine diseases and molecular chaperones

1 reference

12 December 2020

Decreased expression of Hsp27 and Hsp70 in transformed lymphoblastoid cells from patients with spinocerebellar ataxia type 7.

1 reference

12 December 2020

Heat shock response modulators as therapeutic tools for diseases of protein conformation

1 reference

12 December 2020

Down-regulation of heat shock protein 27 in neuronal cells and non-neuronal cells expressing mutant ataxin-3

1 reference

12 December 2020

Pathogenesis of polyglutamine disorders: aggregation revisited

1 reference

12 December 2020

Regulation of heat shock transcription factor 1 by stress-induced SUMO-1 modification

1 reference

12 December 2020

Phosphorylation of serine 303 is a prerequisite for the stress-inducible SUMO modification of heat shock factor 1

1 reference

12 December 2020

Direct sensing of heat and oxidation by Drosophila heat shock transcription factor

1 reference

12 December 2020

Increased huntingtin protein length reduces the number of polyglutamine-induced gene expression changes in mouse models of Huntington's disease

1 reference

12 December 2020

Enhanced SUMOylation in polyglutamine diseases.

1 reference

12 December 2020

Modulation of neurodegeneration by molecular chaperones

1 reference

12 December 2020

Glycogen synthase kinase-3beta inhibitors prevent cellular polyglutamine toxicity caused by the Huntington's disease mutation

1 reference

12 December 2020

Polyglutamine aggregates stimulate ER stress signals and caspase-12 activation

1 reference

12 December 2020

Glycogen synthase kinase 3beta negatively regulates both DNA-binding and transcriptional activities of heat shock factor 1

1 reference

12 December 2020

Hsp70 and Hsp40 attenuate formation of spherical and annular polyglutamine oligomers by partitioning monomer

1 reference

12 December 2020

The glamour and gloom of glycogen synthase kinase-3

1 reference

12 December 2020

SUMO-1 co-localized with mutant atrophin-1 with expanded polyglutamines accelerates intranuclear aggregation and cell death.

1 reference

12 December 2020

Polyglutamine aggregates alter protein folding homeostasis in Caenorhabditis elegans

1 reference

12 December 2020

Potential targets for HSF1 within the preinitiation complex

1 reference

12 December 2020

Genetic modulation of polyglutamine toxicity by protein conjugation pathways in Drosophila

1 reference

12 December 2020

Pathways of chaperone-mediated protein folding in the cytosol

1 reference

12 December 2020

Molecular pathogenesis of spinocerebellar ataxias.

1 reference

12 December 2020

Heat shock proteins as emerging therapeutic targets

1 reference

12 December 2020

A novel therapeutic strategy for polyglutamine diseases by stabilizing aggregation-prone proteins with small molecules

1 reference

12 December 2020

SUMO modification of Huntingtin and Huntington's disease pathology

1 reference

12 December 2020

Cellular toxicity of polyglutamine expansion proteins: mechanism of transcription factor deactivation

1 reference

12 December 2020

The wide spectrum of spinocerebellar ataxias (SCAs)

1 reference

12 December 2020

Global impairment of the ubiquitin-proteasome system by nuclear or cytoplasmic protein aggregates precedes inclusion body formation.

1 reference

12 December 2020

Active HSF1 significantly suppresses polyglutamine aggregate formation in cellular and mouse models

1 reference

12 December 2020

Targeting CREB-binding protein (CBP) loss of function as a therapeutic strategy in neurological disorders

1 reference

12 December 2020

Analysis of the role of heat shock protein (Hsp) molecular chaperones in polyglutamine disease

1 reference

12 December 2020

Protein-misfolding diseases and chaperone-based therapeutic approaches

1 reference

12 December 2020

Recent advances in hereditary spinocerebellar ataxias

1 reference

12 December 2020

Molecular chaperones as modulators of polyglutamine protein aggregation and toxicity

1 reference

12 December 2020

Progressive decrease in chaperone protein levels in a mouse model of Huntington's disease and induction of stress proteins as a therapeutic approach

1 reference

12 December 2020

Dynamic regulation of molecular chaperone gene expression in polyglutamine disease.

1 reference

12 December 2020

Diseases of unstable repeat expansion: mechanisms and common principles

1 reference

12 December 2020

Mechanisms of chaperone suppression of polyglutamine disease: selectivity, synergy and modulation of protein solubility in Drosophila.

1 reference

12 December 2020

c-Jun NH2-terminal kinase targeting and phosphorylation of heat shock factor-1 suppress its transcriptional activity

1 reference

12 December 2020