(Q36863031)

16 August 2017

1 reference

title

Signal peptide peptidases and gamma-secretase: cousins of the same protease family? (English)

1 reference

16 August 2017

2

Christian Haass

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Regina Fluhrer

series ordinal

1

object named as

Regina Fluhrer

1 reference

16 August 2017

1 January 2007

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Neurodegenerative Diseases

16 August 2017

1 reference

16 August 2017

4

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16 August 2017

2-3

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16 August 2017

112-116

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Regulated intramembrane proteolysis: a control mechanism conserved from bacteria to humans

16 August 2017

1 reference

Intramembrane-cleaving proteases: controlled liberation of proteins and bioactive peptides

21 January 2018

1 reference

Two transmembrane aspartates in presenilin-1 required for presenilin endoproteolysis and gamma-secretase activity

21 January 2018

1 reference

Identification of signal peptide peptidase, a presenilin-type aspartic protease

21 January 2018

1 reference

Notch and Presenilin: regulated intramembrane proteolysis links development and degeneration.

21 January 2018

1 reference

Alzheimer disease gamma-secretase: a complex story of GxGD-type presenilin proteases

21 January 2018

1 reference

Take five--BACE and the gamma-secretase quartet conduct Alzheimer's amyloid beta-peptide generation.

21 January 2018

1 reference

Reconstitution of gamma-secretase activity

21 January 2018

1 reference

The role of presenilin cofactors in the gamma-secretase complex

21 January 2018

1 reference

γ-Secretase is a membrane protein complex comprised of presenilin, nicastrin, aph-1, and pen-2

21 January 2018

1 reference

A loss of function mutation of presenilin-2 interferes with amyloid beta-peptide production and notch signaling

21 January 2018

1 reference

Aph-1, Pen-2, and Nicastrin with Presenilin generate an active gamma-Secretase complex

21 January 2018

1 reference

Glycine 384 is required for presenilin-1 function and is conserved in bacterial polytopic aspartyl proteases

21 January 2018

1 reference

Intramembrane-cleaving aspartic proteases and disease: presenilins, signal peptide peptidase and their homologs

21 January 2018

1 reference

Intramembrane proteolysis: theme and variations.

21 January 2018

1 reference

The type 4 prepilin peptidases comprise a novel family of aspartic acid proteases

21 January 2018

1 reference

Presenilin 1 is linked with gamma-secretase activity in the detergent solubilized state

21 January 2018

1 reference

Transition-state analogue inhibitors of gamma-secretase bind directly to presenilin-1.

21 January 2018

1 reference

Identification of a novel family of presenilin homologues

21 January 2018

1 reference

Signal peptide peptidase forms a homodimer that is labeled by an active site-directed gamma-secretase inhibitor

21 January 2018

1 reference

Presenilins mediate a dual intramembranous gamma-secretase cleavage of Notch-1.

21 January 2018

1 reference

Notch signaling: from the outside in

21 January 2018

1 reference

A presenilin dimer at the core of the gamma-secretase enzyme: insights from parallel analysis of Notch 1 and APP proteolysis

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1159/000101835

1 reference

16 August 2017

1 reference

PubMed ID

17596705