(Q36910085)

17 August 2017

A molecular mechanism for therapeutic effects of cGMP-elevating agents in pulmonary arterial hypertension (English)

1 reference

17 August 2017

Raphaela Schwappacher

1

object named as

Raphaela Schwappacher

0 references

Baktybek Kojonazarov

3

object named as

Baktybek Kojonazarov

1 reference

17 August 2017

Raphaela Schwappacher

1

1 reference

17 August 2017

Ana Kilic

2

1 reference

17 August 2017

Michaela Lang

4

1 reference

17 August 2017

Thuan Diep

5

1 reference

17 August 2017

Shunhui Zhuang

6

1 reference

17 August 2017

Thomas Gawlowski

7

1 reference

17 August 2017

Ralph T Schermuly

8

1 reference

17 August 2017

Alexander Pfeifer

9

1 reference

17 August 2017

Gerry R Boss

10

1 reference

17 August 2017

Renate B Pilz

11

1 reference

17 August 2017

language of work or name

English

0 references

publication date

23 April 2013

1 reference

17 August 2017

10

1 reference

Journal of Biological Chemistry

inferred from page(s)

published in

1 reference

17 August 2017

288

1 reference

17 August 2017

23

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17 August 2017

16557-16566

1 reference

describes a project that uses

17 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3675591/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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The soluble guanylate cyclase stimulator riociguat ameliorates pulmonary hypertension induced by hypoxia and SU5416 in rats

29 September 2017

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29 September 2017

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Soluble guanylate cyclase as an emerging therapeutic target in cardiopulmonary disease

29 September 2017

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29 September 2017

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Reduced levels of two modifiers of epigenetic gene silencing, Dnmt3a and Trim28, cause increased phenotypic noise

29 September 2017

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29 September 2017

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Variable Na(v)1.5 protein expression from the wild-type allele correlates with the penetrance of cardiac conduction disease in the Scn5a(+/-) mouse model

29 September 2017

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29 September 2017

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Persistent eNOS activation secondary to caveolin-1 deficiency induces pulmonary hypertension in mice and humans through PKG nitration

29 September 2017

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Novel crosstalk to BMP signalling: cGMP-dependent kinase I modulates BMP receptor and Smad activity

29 September 2017

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Penetrance of pulmonary arterial hypertension is modulated by the expression of normal BMPR2 allele

29 September 2017

1 reference

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Mre11 nuclease activity has essential roles in DNA repair and genomic stability distinct from ATM activation

29 September 2017

1 reference

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Molecular pathogenesis of pulmonary arterial hypertension

29 September 2017

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An antiproliferative BMP-2/PPARgamma/apoE axis in human and murine SMCs and its role in pulmonary hypertension

29 September 2017

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Dorsomorphin inhibits BMP signals required for embryogenesis and iron metabolism

29 September 2017

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Control of phenotypic plasticity of smooth muscle cells by bone morphogenetic protein signaling through the myocardin-related transcription factors

29 September 2017

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BMP-dependent activation of caspase-9 and caspase-8 mediates apoptosis in pulmonary artery smooth muscle cells

29 September 2017

1 reference

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Divergent effects of BMP-2 on gene expression in pulmonary artery smooth muscle cells from normal subjects and patients with idiopathic pulmonary arterial hypertension

29 September 2017

1 reference

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Regulation of vascular smooth muscle cell phenotype by cyclic GMP and cyclic GMP-dependent protein kinase

29 September 2017

1 reference

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Increased susceptibility to pulmonary hypertension in heterozygous BMPR2-mutant mice

29 September 2017

1 reference

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Molecular regulation of vascular smooth muscle cell differentiation in development and disease

29 September 2017

1 reference

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Disruption of the Rad9/Rad1/Hus1 (9-1-1) complex leads to checkpoint signaling and replication defects

29 September 2017

1 reference

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Altered growth responses of pulmonary artery smooth muscle cells from patients with primary pulmonary hypertension to transforming growth factor-beta(1) and bone morphogenetic proteins

29 September 2017

1 reference

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Gene expression patterns in the lungs of patients with primary pulmonary hypertension: a gene microarray analysis

29 September 2017

1 reference

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Cyclic GMP-dependent protein kinase regulates vascular smooth muscle cell phenotype

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3675591

Protein kinase G-I deficiency induces pulmonary hypertension through Rho A/Rho kinase activation

29 September 2017

1 reference

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Nitrite potently inhibits hypoxic and inflammatory pulmonary arterial hypertension and smooth muscle proliferation via xanthine oxidoreductase-dependent nitric oxide generation

27 June 2018

1 reference

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The soluble guanylate cyclase activator HMR1766 reverses hypoxia-induced experimental pulmonary hypertension in mice.

27 June 2018

1 reference

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Defective smooth muscle regulation in cGMP kinase I-deficient mice

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3675591

Smad-dependent and smad-independent induction of id1 by prostacyclin analogues inhibits proliferation of pulmonary artery smooth muscle cells in vitro and in vivo.

27 June 2018

1 reference

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The four-and-a-half LIM domain protein 2 regulates vascular smooth muscle phenotype and vascular tone

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3675591

Synergy between natriuretic peptides and phosphodiesterase 5 inhibitors ameliorates pulmonary arterial hypertension.

4 September 2018

1 reference

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Mutations in bone morphogenetic protein type II receptor cause dysregulation of Id gene expression in pulmonary artery smooth muscle cells: implications for familial pulmonary arterial hypertension

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3675591

A cysteine-rich LIM-only protein mediates regulation of smooth muscle-specific gene expression by cGMP-dependent protein kinase

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3675591

Molecular effects of loss of BMPR2 signaling in smooth muscle in a transgenic mouse model of PAH.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3675591

Activation of soluble guanylate cyclase reverses experimental pulmonary hypertension and vascular remodeling

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3675591

BMPR-II heterozygous mice have mild pulmonary hypertension and an impaired pulmonary vascular remodeling response to prolonged hypoxia.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3675591

Pulmonary hypertension in transgenic mice expressing a dominant-negative BMPRII gene in smooth muscle

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3675591

Primary pulmonary hypertension is associated with reduced pulmonary vascular expression of type II bone morphogenetic protein receptor

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3675591

Adenovirus-mediated gene transfer of cGMP-dependent protein kinase increases the sensitivity of cultured vascular smooth muscle cells to the antiproliferative and pro-apoptotic effects of nitric oxide/cGMP.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3675591

Dysfunctional Smad Signaling Contributes to Abnormal Smooth Muscle Cell Proliferation in Familial Pulmonary Arterial Hypertension

4 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1074%2FJBC.M113.458729

Rodent models of PAH: are we there yet?

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1074%2FJBC.M113.458729

Increased susceptibility to hypoxic pulmonary hypertension in Bmpr2 mutant mice is associated with endothelial dysfunction in the pulmonary vasculature

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1074%2FJBC.M113.458729

Formation of plexiform lesions in experimental severe pulmonary arterial hypertension

21 January 2018

1 reference

12 December 2020

Bone morphogenetic proteins induce apoptosis in human pulmonary vascular smooth muscle cells

1 reference

12 December 2020

Cyclic GMP-dependent protein kinase inhibits osteopontin and thrombospondin production in rat aortic smooth muscle cells

1 reference

12 December 2020

Dysregulated Bone Morphogenetic Protein Signaling in Monocrotaline-Induced Pulmonary Arterial Hypertension

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.M113.458729

1 reference

17 August 2017

1 reference

17 August 2017

1 reference