(Q36913240)

17 August 2017

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title

Therapy-related acute myelogenous leukemia and myelodysplastic syndrome (English)

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17 August 2017

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1

Gautam Borthakur

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17 August 2017

And Elihu E Estey

2

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17 August 2017

publication date

1 September 2007

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17 August 2017

published in

Current Oncology Reports

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17 August 2017

volume

9

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17 August 2017

issue

5

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17 August 2017

page(s)

373-377

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DNA cleavage within the MLL breakpoint cluster region is a specific event which occurs as part of higher-order chromatin fragmentation during the initial stages of apoptosis

17 August 2017

cites work

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS11912-007-0050-Z

Duplication or amplification of chromosome band 11q23, including the unrearranged MLL gene, is a recurrent abnormality in therapy-related MDS and AML, and is closely related to mutation of the TP53 gene and to previous therapy with alkylating agents

21 January 2018

1 reference

12 December 2020

Moderate increase of secondary hematologic malignancies after myeloablative radiochemotherapy and autologous stem-cell transplantation in patients with indolent lymphoma: results of a prospective randomized trial of the German Low Grade Lymphoma Stu

1 reference

12 December 2020

ETO, fusion partner in t(8;21) acute myeloid leukemia, represses transcription by interaction with the human N-CoR/mSin3/HDAC1 complex

1 reference

12 December 2020

Incidence of acute nonlymphocytic leukemia, preleukemia, and acute myeloproliferative syndrome up to 10 years after treatment of Hodgkin's disease

1 reference

12 December 2020

High incidence of myelodysplasia and secondary leukaemia in the UK Medical Research Council Pilot of autografting in chronic lymphocytic leukaemia

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12 December 2020

Targeting aberrant transcriptional repression in acute myeloid leukemia.

1 reference

12 December 2020

Causality of myelodysplasia and acute myeloid leukemia and their genetic abnormalities

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12 December 2020

Multiple myeloma and acute myelomonocytic leukemia

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12 December 2020

DNA topoisomerase II in therapy-related acute promyelocytic leukemia.

1 reference

12 December 2020

Does autologous transplantation directly increase the risk of secondary leukemia in lymphoma patients?

1 reference

12 December 2020

Balanced chromosome abnormalities inv(16) and t(15;17) in therapy-related myelodysplastic syndromes and acute leukemia: report from an international workshop.

1 reference

12 December 2020

Secondary acute myeloid leukaemia: results of conventional treatments. Experience of GIMEMA trials

1 reference

12 December 2020

The presence of an HLA-identical sibling donor has no impact on outcome of patients with high-risk MDS or secondary AML (sAML) treated with intensive chemotherapy followed by transplantation: results of a prospective study of the EORTC, EBMT, SAKK a

1 reference

12 December 2020

Polymorphisms in genes involved in homologous recombination repair interact to increase the risk of developing acute myeloid leukemia

1 reference

12 December 2020

Leukemia and Preleukemia after Adjuvant Treatment of Gastrointestinal Cancer with Semustine (Methyl-CCNU)

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12 December 2020

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12 December 2020

Alternative genetic pathways and cooperating genetic abnormalities in the pathogenesis of therapy-related myelodysplasia and acute myeloid leukemia

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12 December 2020

Mechanisms of MLL gene rearrangement: site-specific DNA cleavage within the breakpoint cluster region is independent of chromosomal context

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12 December 2020

Genetics of myeloid malignancies: pathogenetic and clinical implications

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12 December 2020

Increased incidence of acute leukemia in polycythemia vera associated with chlorambucil therapy.

1 reference

12 December 2020

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12 December 2020

Intensive chemotherapy with idarubicin, cytosine arabinoside, and granulocyte colony-stimulating factor (G-CSF) in patients with secondary and therapy-related acute myelogenous leukemia. Club de Réflexion en Hématologie

1 reference

12 December 2020

Risk of therapy-related leukaemia and preleukaemia after Hodgkin's disease. Relation to age, cumulative dose of alkylating agents, and time from chemotherapy.

1 reference

12 December 2020

Clonal haemopoiesis may occur after conventional chemotherapy and is associated with accelerated telomere shortening and defects in the NQO1 pathway; possible mechanisms leading to an increased risk of t-AML/MDS.

1 reference

12 December 2020

Rare CBFB-MYH11 fusion transcripts in AML with inv(16)/t(16;16) are associated with therapy-related AML M4eo, atypical cytomorphology, atypical immunophenotype, atypical additional chromosomal rearrangements and low white blood cell count: a study o

1 reference

12 December 2020

Pooled analysis of clinical and cytogenetic features in treatment-related and de novo adult acute myeloid leukemia and myelodysplastic syndromes based on a consecutive series of 761 patients analyzed 1976-1993 and on 5098 unselected cases reported i

1 reference

12 December 2020

Mutations of genes in the receptor tyrosine kinase (RTK)/RAS-BRAF signal transduction pathway in therapy-related myelodysplasia and acute myeloid leukemia

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12 December 2020

Secondary acute myeloid leukemia in children treated for acute lymphoid leukemia

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12 December 2020

Early secondary acute myelogenous leukemia in breast cancer patients after treatment with mitoxantrone, cyclophosphamide, fluorouracil and radiation therapy

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12 December 2020

Profile of polymorphisms of drug-metabolising enzymes and the risk of therapy-related leukaemia

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12 December 2020

Polymorphisms in human homeobox HLX1 and DNA repair RAD51 genes increase the risk of therapy-related acute myeloid leukemia

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12 December 2020

Poor metabolizers at the cytochrome P450 2D6 and 2C19 loci are at increased risk of developing adult acute leukaemia.

1 reference

12 December 2020

Increased risk of myelodysplasia and leukaemia after etoposide, cisplatin, and bleomycin for germ-cell tumours

1 reference

12 December 2020

Chromosome band 11q23 translocation breakpoints are DNA topoisomerase II cleavage sites

1 reference

12 December 2020

P-glycoprotein (PGP), and not lung resistance-related protein (LRP), is a negative prognostic factor in secondary leukemias.

1 reference

12 December 2020

Chemotherapy only compared to chemotherapy followed by transplantation in high risk myelodysplastic syndrome and secondary acute myeloid leukemia; two parallel studies adjusted for various prognostic factors

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12 December 2020

Genomic DNA breakpoints in AML1/RUNX1 and ETO cluster with topoisomerase II DNA cleavage and DNase I hypersensitive sites in t(8;21) leukemia.

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12 December 2020

The molecular basis of leukemia

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12 December 2020

Methylation of p15INK4B is common, is associated with deletion of genes on chromosome arm 7q and predicts a poor prognosis in therapy-related myelodysplasia and acute myeloid leukemia.

1 reference

12 December 2020

Mutations with loss of heterozygosity of p53 are common in therapy-related myelodysplasia and acute myeloid leukemia after exposure to alkylating agents and significantly associated with deletion or loss of 5q, a complex karyotype, and a poor progno

1 reference

12 December 2020

ETO, a target of t(8;21) in acute leukemia, makes distinct contacts with multiple histone deacetylases and binds mSin3A through its oligomerization domain

1 reference

12 December 2020

Acute Leukemia after Alkylating-Agent Therapy of Ovarian Cancer

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12 December 2020

Myelodysplasia and acute myeloid leukaemia following adjuvant chemotherapy for breast cancer using mitoxantrone and methotrexate with or without mitomycin

1 reference

12 December 2020

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12 December 2020

Acute nonlymphocytic leukemia following etoposide and cisplatin combination chemotherapy for advanced non-small-cell carcinoma of the lung

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12 December 2020

10.1007/S11912-007-0050-Z

Identifiers

DOI

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17 August 2017

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