(Q36944104)

English

Screening Outside the Catalytic Site: Inhibition of Macromolecular Inter-actions Through Structure-Based Virtual Ligand Screening Experiments.

scientific article published on 10 March 2008

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18949072%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

Screening Outside the Catalytic Site: Inhibition of Macromolecular Inter-actions Through Structure-Based Virtual Ligand Screening Experiments (English)

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25 December 2019

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based on heuristic

inferred from title

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25 December 2019

Bruno O Villoutreix

5

object named as

Bruno O Villoutreix

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25 December 2019

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Olivier Sperandio

1

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25 December 2019

Kenneth Segers

3

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25 December 2019

Gerry A F Nicolaes

4

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25 December 2019

publication date

10 March 2008

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25 December 2019

The Open Biochemistry Journal

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25 December 2019

2

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25 December 2019

29-37

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25 December 2019

In silico-in vitro screening of protein-protein interactions: towards the next generation of therapeutics

1 reference

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1 reference

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PocketPicker: analysis of ligand binding-sites with shape descriptors.

1 reference

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Human protein-protein interaction networks and the value for drug discovery

1 reference

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1 reference

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Design of protein membrane interaction inhibitors by virtual ligand screening, proof of concept with the C2 domain of factor V

1 reference

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29 September 2017

Chemogenomics approaches to novel target discovery

1 reference

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29 September 2017

Chemogenomic approaches to rational drug design

1 reference

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29 September 2017

ProMateus--an open research approach to protein-binding sites analysis

1 reference

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29 September 2017

Strategies to search and design stabilizers of protein-protein interactions: a feasibility study

1 reference

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29 September 2017

Molecular similarity analysis in virtual screening: foundations, limitations and novel approaches

1 reference

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29 September 2017

The molecular architecture of protein-protein binding sites.

1 reference

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29 September 2017

Similarity-based virtual screening using 2D fingerprints

1 reference

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Receptor-based computational screening of compound databases: the main docking-scoring engines

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Prediction of protein-ligand interactions. Docking and scoring: successes and gaps

1 reference

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29 September 2017

Chemogenomics: structuring the drug discovery process to gene families.

1 reference

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Streamlining lead discovery by aligning in silico and high-throughput screening

1 reference

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Discovery of a nanomolar inhibitor of the human murine double minute 2 (MDM2)-p53 interaction through an integrated, virtual database screening strategy.

1 reference

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29 September 2017

Obtaining and screening compound collections: a user's guide and a call to chemists

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29 September 2017

Similarity based virtual screening: a tool for targeted library design

1 reference

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29 September 2017

Between a rock and a hard place?

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29 September 2017

Predicting protein druggability

1 reference

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29 September 2017

Strategies for targeting protein-protein interactions with synthetic agents.

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Protein-protein interactions and cancer: small molecules going in for the kill

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29 September 2017

Membrane-protein interactions in cell signaling and membrane trafficking

1 reference

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29 September 2017

Regulation of blood coagulation by the protein C anticoagulant pathway: novel insights into structure-function relationships and molecular recognition

1 reference

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29 September 2017

New methodologies for ligand-based virtual screening

1 reference

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29 September 2017

A shape-based 3-D scaffold hopping method and its application to a bacterial protein-protein interaction

1 reference

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29 September 2017

Comprehensive identification of "druggable" protein ligand binding sites.

1 reference

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29 September 2017

Online predicted human interaction database

1 reference

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29 September 2017

Docking and scoring in virtual screening for drug discovery: methods and applications

1 reference

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29 September 2017

Emerging classes of protein-protein interaction inhibitors and new tools for their development

1 reference

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29 September 2017

Small-molecule inhibitors of protein-protein interactions: progressing towards the dream

1 reference

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29 September 2017

Chemical feature-based pharmacophores and virtual library screening for discovery of new leads.

1 reference

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29 September 2017

Discovery of diverse thyroid hormone receptor antagonists by high-throughput docking

1 reference

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29 September 2017

Protein-protein interactions: structurally conserved residues distinguish between binding sites and exposed protein surfaces

1 reference

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29 September 2017

Surflex: fully automatic flexible molecular docking using a molecular similarity-based search engine

1 reference

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29 September 2017

Small molecule antagonists of proteins

1 reference

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Factor V and thrombotic disease: description of a janus-faced protein

1 reference

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29 September 2017

Unraveling hot spots in binding interfaces: progress and challenges

1 reference

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29 September 2017

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G-protein signaling through tubby proteins

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The productive conformation of arachidonic acid bound to prostaglandin synthase

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1 reference

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Anatomy of hot spots in protein interfaces

1 reference

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Binding in the growth hormone receptor complex

1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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Protein−Protein Interactions: Interface Structure, Binding Thermodynamics, and Mutational Analysis

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A preliminary in silico lead series of 2-phthalimidinoglutaric acid analogues designed as MMP-3 inhibitors

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.2174/1874091X00802010029

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18949072%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

release_idjmmeip3fg5xbvgqdbjadcwtm

1 reference

https://api.fatcat.wiki/v0/release/idjmmeip3fg5xbvgqdbjadcwtm

24 November 2022

based on heuristic

mapped directly with Wikidata item

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18949072%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18949072%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

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