(Q36946774)

17 August 2017

1 reference

title

Ubiquitin ligases in cancer: ushers for degradation (English)

1 reference

17 August 2017

Kim Newton

1

1 reference

17 August 2017

Domagoj Vucic

series ordinal

2

1 reference

17 August 2017

publication date

1 September 2007

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17 August 2017

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17 August 2017

volume

25

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17 August 2017

issue

6

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17 August 2017

page(s)

502-513

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

17 August 2017

1 reference

Multiubiquitylation by E4 enzymes: 'one size' doesn't fit all.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

A novel ubiquitination factor, E4, is involved in multiubiquitin chain assembly.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

Regulation of Membrane Protein Transport by Ubiquitin and Ubiquitin-Binding Proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

Polyubiquitin chains: polymeric protein signals

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

Ubiquitin-binding domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

Noncanonical MMS2-encoded ubiquitin-conjugating enzyme functions in assembly of novel polyubiquitin chains for DNA repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

Activation of the IkappaB kinase complex by TRAF6 requires a dimeric ubiquitin-conjugating enzyme complex and a unique polyubiquitin chain

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

Mdm2 is a RING finger-dependent ubiquitin protein ligase for itself and p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

F-box proteins are receptors that recruit phosphorylated substrates to the SCF ubiquitin-ligase complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

SCF and Cullin/Ring H2-based ubiquitin ligases

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

CHIP is a U-box-dependent E3 ubiquitin ligase: identification of Hsc70 as a target for ubiquitylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

CHIP is a chaperone-dependent E3 ligase that ubiquitylates unfolded protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

The PHD domain of MEKK1 acts as an E3 ubiquitin ligase and mediates ubiquitination and degradation of ERK1/2

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

De-ubiquitination and ubiquitin ligase domains of A20 downregulate NF-kappaB signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

Bcl10 activates the NF-kappaB pathway through ubiquitination of NEMO

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

Proline hydroxylation and gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

Ubiquitination of hypoxia-inducible factor requires direct binding to the beta-domain of the von Hippel-Lindau protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

Binding of the von Hippel-Lindau tumor suppressor protein to Elongin B and C

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

Inhibition of transcription elongation by the VHL tumor suppressor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

The von Hippel-Lindau tumor-suppressor gene product forms a stable complex with human CUL-2, a member of the Cdc53 family of proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

Rbx1, a component of the VHL tumor suppressor complex and SCF ubiquitin ligase

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

HIF-1alpha binding to VHL is regulated by stimulus-sensitive proline hydroxylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

Independent function of two destruction domains in hypoxia-inducible factor-alpha chains activated by prolyl hydroxylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

Inhibition of HIF is necessary for tumor suppression by the von Hippel-Lindau protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

The contribution of VHL substrate binding and HIF1-alpha to the phenotype of VHL loss in renal cell carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

Inhibition of HIF2alpha is sufficient to suppress pVHL-defective tumor growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

The von Hippel-Lindau tumor suppressor protein: new insights into oxygen sensing and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

Regulation of microtubule stability by the von Hippel-Lindau tumour suppressor protein pVHL.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

Identification of the RNA polymerase II subunit hsRPB7 as a novel target of the von Hippel-Lindau protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

von Hippel-Lindau tumor suppressor protein regulates the assembly of intercellular junctions in renal cancer cells through hypoxia-inducible factor-independent mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

Clusterin is a secreted marker for a hypoxia-inducible factor-independent function of the von Hippel-Lindau tumor suppressor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

c-Cbl and Cbl-b ubiquitin ligases: substrate diversity and the negative regulation of signalling responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

The tyrosine kinase negative regulator c-Cbl as a RING-type, E2-dependent ubiquitin-protein ligase

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

Ubiquitin ligase activity and tyrosine phosphorylation underlie suppression of growth factor signaling by c-Cbl/Sli-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

The non-receptor tyrosine kinase Syk is a target of Cbl-mediated ubiquitylation upon B-cell receptor stimulation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

Multiple monoubiquitination of RTKs is sufficient for their endocytosis and degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

Escape from Cbl-mediated downregulation: a recurrent theme for oncogenic deregulation of receptor tyrosine kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

Somatic mutations lead to an oncogenic deletion of met in lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

RING finger mutations that abolish c-Cbl-directed polyubiquitination and downregulation of the EGF receptor are insufficient for cell transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

21 January 2018

Surfing the p53 network

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

p53 ubiquitination: Mdm2 and beyond

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

Pirh2, a p53-induced ubiquitin-protein ligase, promotes p53 degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

COP1, the negative regulator of p53, is overexpressed in breast and ovarian adenocarcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

ARF-BP1/Mule is a critical mediator of the ARF tumor suppressor

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

Rescue of embryonic lethality in Mdm2-deficient mice by absence of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

Rescue of early embryonic lethality in mdm2-deficient mice by deletion of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

The MDM2 gene amplification database

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

A single nucleotide polymorphism in the MDM2 promoter attenuates the p53 tumor suppressor pathway and accelerates tumor formation in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

Association between MDM2-SNP309 and age at colorectal cancer diagnosis according to p53 mutation status.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

Impact of the MDM2 SNP309 and p53 Arg72Pro polymorphism on age of tumour onset in Li-Fraumeni syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

Immune response in silico (IRIS): immune-specific genes identified from a compendium of microarray expression data.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

Mechanisms and genes of cellular suicide

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

Apoptosis in the pathogenesis and treatment of disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

IAP proteins: blocking the road to death's door

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

IAPs, RINGs and ubiquitylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

Proteasome-mediated degradation of Smac during apoptosis: XIAP promotes Smac ubiquitination in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

Dual role of BRUCE as an antiapoptotic IAP and a chimeric E2/E3 ubiquitin ligase

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

Apollon ubiquitinates SMAC and caspase-9, and has an essential cytoprotection function

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

Ubiquitin-protein ligase activity of X-linked inhibitor of apoptosis protein promotes proteasomal degradation of caspase-3 and enhances its anti-apoptotic effect in Fas-induced cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

IAPs--the ubiquitin connection

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

Determination of cell survival by RING-mediated regulation of inhibitor of apoptosis (IAP) protein abundance

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

Smac/DIABLO selectively reduces the levels of c-IAP1 and c-IAP2 but not that of XIAP and livin in HeLa cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

Degradation of DIAP1 by the N-end rule pathway is essential for regulating apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

Induction of apoptosis by Drosophila reaper, hid and grim through inhibition of IAP function

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

The Bcl-2 family: roles in cell survival and oncogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

Dephosphorylation targets Bcl-2 for ubiquitin-dependent degradation: a link between the apoptosome and the proteasome pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

Ubiquitin ligases in malignant lymphoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

Proteasomes modulate balance among proapoptotic and antiapoptotic Bcl-2 family members and compromise functioning of the electron transport chain in leukemic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

Mule/ARF-BP1, a BH3-only E3 ubiquitin ligase, catalyzes the polyubiquitination of Mcl-1 and regulates apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

Life, death, and ubiquitin: taming the mule.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

The E3 ubiquitin ligase itch couples JNK activation to TNFalpha-induced cell death by inducing c-FLIP(L) turnover

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

NF-kappaB regulation in the immune system

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

Regulating the regulators: control of protein ubiquitination and ubiquitin-like modifications by extracellular stimuli

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

Immunity by ubiquitylation: a reversible process of modification

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

Tumor necrosis factor receptor-associated factors (TRAFs)--a family of adapter proteins that regulates life and death

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

The death domain kinase RIP mediates the TNF-induced NF-kappaB signal

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

Critical roles of TRAF2 and TRAF5 in tumor necrosis factor-induced NF-kappa B activation and protection from cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

Activation of IKK by TNFalpha requires site-specific ubiquitination of RIP1 and polyubiquitin binding by NEMO

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

Sensing of Lys 63-linked polyubiquitination by NEMO is a key event in NF-kappaB activation [corrected]

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

TAB2 and TAB3 activate the NF-kappaB pathway through binding to polyubiquitin chains

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

TNF-RII and c-IAP1 mediate ubiquitination and degradation of TRAF2

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

A pervasive role of ubiquitin conjugation in activation and termination of IkappaB kinase pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

Identification of paracaspases and metacaspases: two ancient families of caspase-like proteins, one of which plays a key role in MALT lymphoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

Regulation of NF-κB-Dependent Lymphocyte Activation and Development by Paracaspase

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

Differential Requirement for Malt1 in T and B Cell Antigen Receptor Signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

Mice lacking the CARD of CARMA1 exhibit defective B lymphocyte development and impaired proliferation of their B and T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

Requirement for CARMA1 in antigen receptor-induced NF-kappa B activation and lymphocyte proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

Identifying the MAGUK protein Carma-1 as a central regulator of humoral immune responses and atopy by genome-wide mouse mutagenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

The MAGUK family protein CARD11 is essential for lymphocyte activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

21 January 2018

Update on MALT lymphomas

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

A novel gene, MALT1 at 18q21, is involved in t(11;18) (q21;q21) found in low-grade B-cell lymphoma of mucosa-associated lymphoid tissue

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

Constitutive NF-kappaB activation by the t(11;18)(q21;q21) product in MALT lymphoma is linked to deregulated ubiquitin ligase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

Identification of ubiquitination sites and determination of ubiquitin-chain architectures by mass spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

Multisite phosphorylation by Cdk2 and GSK3 controls cyclin E degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

The Fbw7 tumor suppressor regulates glycogen synthase kinase 3 phosphorylation-dependent c-Myc protein degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

Phosphorylation-dependent degradation of c-Myc is mediated by the F-box protein Fbw7

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

The v-Jun point mutation allows c-Jun to escape GSK3-dependent recognition and destruction by the Fbw7 ubiquitin ligase

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

Inactivation of hCDC4 can cause chromosomal instability

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

CDC4 mutations occur in a subset of colorectal cancers but are not predicted to cause loss of function and are not associated with chromosomal instability

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

Deregulated degradation of the cdk inhibitor p27 and malignant transformation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

Structural basis of the Cks1-dependent recognition of p27(Kip1) by the SCF(Skp2) ubiquitin ligase

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

Role of Cks1 overexpression in oral squamous cell carcinomas: cooperation with Skp2 in promoting p27 degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

The expression of the ubiquitin ligase subunit Cks1 in human breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

An architectural map of the anaphase-promoting complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

ROC1, a homolog of APC11, represents a family of cullin partners with an associated ubiquitin ligase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

The APC11 RING-H2 finger mediates E2-dependent ubiquitination

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

The RING-H2 finger protein APC11 and the E2 enzyme UBC4 are sufficient to ubiquitinate substrates of the anaphase-promoting complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

CDC20 and CDH1: a family of substrate-specific activators of APC-dependent proteolysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

Emi1 is a mitotic regulator that interacts with Cdc20 and inhibits the anaphase promoting complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

The cyclin-ubiquitin ligase activity of cyclosome/APC is jointly activated by protein kinases Cdk1-cyclin B and Plk.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

Mitotic regulation of the human anaphase-promoting complex by phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

APC/C and SCF: controlling each other and the cell cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

The evi5 oncogene regulates cyclin accumulation by stabilizing the anaphase-promoting complex inhibitor emi1

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

Overview of history and progress in BRCA1 research: the first BRCA1 decade

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

BRCA1 in breast and ovarian cancer predisposition

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

Identification of a RING protein that can interact in vivo with the BRCA1 gene product

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

Enhancement of BRCA1 E3 ubiquitin ligase activity through direct interaction with the BARD1 protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

The multiple nuclear functions of BRCA1: transcription, ubiquitination and DNA repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

Mass spectrometric and mutational analyses reveal Lys-6-linked polyubiquitin chains catalyzed by BRCA1-BARD1 ubiquitin ligase

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

The BRCA1/BARD1 heterodimer assembles polyubiquitin chains through an unconventional linkage involving lysine residue K6 of ubiquitin

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

The cancer-predisposing mutation C61G disrupts homodimer formation in the NH2-terminal BRCA1 RING finger domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

Structure of the Cand1-Cul1-Roc1 complex reveals regulatory mechanisms for the assembly of the multisubunit cullin-dependent ubiquitin ligases

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

Nedd8 modification of cul-1 activates SCF(beta(TrCP))-dependent ubiquitination of IkappaBalpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

Conjugation of Nedd8 to CUL1 enhances the ability of the ROC1-CUL1 complex to promote ubiquitin polymerization

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

Promotion of NEDD-CUL1 conjugate cleavage by COP9 signalosome

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

NEDD8 modification of CUL1 dissociates p120(CAND1), an inhibitor of CUL1-SKP1 binding and SCF ligases

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

CAND1 binds to unneddylated CUL1 and regulates the formation of SCF ubiquitin E3 ligase complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

Targeted silencing of Jab1/Csn5 in human cells downregulates SCF activity through reduction of F-box protein levels

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

The emerging role of the COP9 signalosome in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

Identification of the familial cylindromatosis tumour-suppressor gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

Cyld inhibits tumor cell proliferation by blocking Bcl-3-dependent NF-kappaB signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

CYLD is a deubiquitinating enzyme that negatively regulates NF-kappaB activation by TNFR family members

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

Loss of the cylindromatosis tumour suppressor inhibits apoptosis by activating NF-kappaB

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

The tumour suppressor CYLD negatively regulates NF-kappaB signalling by deubiquitination

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

Regulation of T cell development by the deubiquitinating enzyme CYLD

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

Human disorders of ubiquitination and proteasomal degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

Ubiquitylation and cell signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

RING finger ubiquitin protein ligases: implications for tumorigenesis, metastasis and for molecular targets in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

Update on the proteasome inhibitor bortezomib in hematologic malignancies

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

Development of the proteasome inhibitor Velcade (Bortezomib).

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

Small molecule inhibitors of HDM2 ubiquitin ligase activity stabilize and activate p53 in cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

Themes and variations on ubiquitylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

In vivo activation of the p53 pathway by small-molecule antagonists of MDM2

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

Keeping p53 in check: essential and synergistic functions of Mdm2 and Mdm4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

TAK1, but not TAB1 or TAB2, plays an essential role in multiple signaling pathways in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

Ubiquitination of RIP Is Required for Tumor Necrosis Factor α-induced NF-κB Activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

Quantitative analysis of in vitro ubiquitinated cyclin B1 reveals complex chain topology

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900701508041

10.1080/07357900701508041

21 January 2018

Identifiers

DOI

1 reference

17 August 2017

1 reference