(Q36949259)

17 August 2017

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title

Analysis of microRNA effector functions in vitro (English)

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17 August 2017

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2

John G Doench

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17 August 2017

Bingbing Wang

1

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17 August 2017

Carl D Novina

series ordinal

3

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17 August 2017

publication date

1 October 2007

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17 August 2017

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17 August 2017

volume

43

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17 August 2017

issue

2

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17 August 2017

page(s)

91-104

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microPrimer: the biogenesis and function of microRNA.

17 August 2017

cites work

1 reference

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Dicer is essential for formation of the heterochromatin structure in vertebrate cells

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Dicer-deficient mouse embryonic stem cells are defective in differentiation and centromeric silencing

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The RNaseIII enzyme Dicer is required for morphogenesis but not patterning of the vertebrate limb

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MicroRNAs modulate hematopoietic lineage differentiation

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The microRNA miR-181 targets the homeobox protein Hox-A11 during mammalian myoblast differentiation

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MicroRNA-cancer connection: the beginning of a new tale

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Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets

7 January 2021

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Systematic discovery of regulatory motifs in human promoters and 3' UTRs by comparison of several mammals

7 January 2021

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MicroRNA-directed cleavage of HOXB8 mRNA

7 January 2021

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MicroRNA Mirn122a reduces expression of the posttranscriptionally regulated germ cell transition protein 2 (Tnp2) messenger RNA (mRNA) by mRNA cleavage.

7 January 2021

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miRNPs: a novel class of ribonucleoproteins containing numerous microRNAs

7 January 2021

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A microRNA in a multiple-turnover RNAi enzyme complex

7 January 2021

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An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells

7 January 2021

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Targeted mRNA degradation by double-stranded RNA in vitro

7 January 2021

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RNAi: double-stranded RNA directs the ATP-dependent cleavage of mRNA at 21 to 23 nucleotide intervals

7 January 2021

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siRNAs can function as miRNAs

7 January 2021

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MicroRNAs control translation initiation by inhibiting eukaryotic initiation factor 4E/cap and poly(A) tail function

7 January 2021

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Short RNAs repress translation after initiation in mammalian cells.

7 January 2021

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Argonaute2 is the catalytic engine of mammalian RNAi

7 January 2021

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Recapitulation of short RNA-directed translational gene silencing in vitro

7 January 2021

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Argonaute2, a link between genetic and biochemical analyses of RNAi

7 January 2021

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Single-stranded antisense siRNAs guide target RNA cleavage in RNAi

7 January 2021

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The rde-1 gene, RNA interference, and transposon silencing in C. elegans

7 January 2021

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RNAi-mediated targeting of heterochromatin by the RITS complex

7 January 2021

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Domains in gene silencing and cell differentiation proteins: the novel PAZ domain and redefinition of the Piwi domain

7 January 2021

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Human Argonaute2 mediates RNA cleavage targeted by miRNAs and siRNAs

7 January 2021

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Purified Argonaute2 and an siRNA form recombinant human RISC

7 January 2021

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Assembly and function of RNA silencing complexes

7 January 2021

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A Dicer-2-dependent 80s complex cleaves targeted mRNAs during RNAi in Drosophila

7 January 2021

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A Drosophila fragile X protein interacts with components of RNAi and ribosomal proteins

7 January 2021

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Human let-7a miRNA blocks protein production on actively translating polyribosomes

7 January 2021

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Evidence that microRNAs are associated with translating messenger RNAs in human cells

7 January 2021

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Inhibition of translational initiation by Let-7 MicroRNA in human cells

7 January 2021

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The lin-4 regulatory RNA controls developmental timing in Caenorhabditis elegans by blocking LIN-14 protein synthesis after the initiation of translation

7 January 2021

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Two genetic circuits repress the Caenorhabditis elegans heterochronic gene lin-28 after translation initiation

7 January 2021

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MicroRNA-dependent localization of targeted mRNAs to mammalian P-bodies

7 January 2021

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Argonaute 2/RISC resides in sites of mammalian mRNA decay known as cytoplasmic bodies

7 January 2021

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Quantitative analysis of Argonaute protein reveals microRNA-dependent localization to stress granules

7 January 2021

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Role for a bidentate ribonuclease in the initiation step of RNA interference

7 January 2021

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Ribonuclease activity and RNA binding of recombinant human Dicer

7 January 2021

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Human Dicer preferentially cleaves dsRNAs at their termini without a requirement for ATP

7 January 2021

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The nuclear RNase III Drosha initiates microRNA processing

7 January 2021

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Processing of primary microRNAs by the Microprocessor complex

7 January 2021

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The Microprocessor complex mediates the genesis of microRNAs

7 January 2021

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Identification of Drosophila MicroRNA targets

7 January 2021

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Prediction of mammalian microRNA targets

7 January 2021

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Molecular requirements for RNA-induced silencing complex assembly in the Drosophila RNA interference pathway.

7 January 2021

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TRBP recruits the Dicer complex to Ago2 for microRNA processing and gene silencing

7 January 2021

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Sequence-specific inhibition of small RNA function

7 January 2021

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Sequence-specific inhibition of microRNA- and siRNA-induced RNA silencing

7 January 2021

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Silencing of microRNAs in vivo with 'antagomirs'

7 January 2021

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Therapeutic silencing of an endogenous gene by systemic administration of modified siRNAs

7 January 2021

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An RNA 5'-triphosphatase related to the protein tyrosine phosphatases

7 January 2021

1 reference

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Recombinant human mRNA cap methyltransferase binds capping enzyme/RNA polymerase IIo complexes

7 January 2021

1 reference

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The yeast capping enzyme represses RNA polymerase II transcription

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.04.003

Kinetic studies of yeast polyA polymerase indicate an induced fit mechanism for nucleotide specificity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.04.003

Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.04.003

Coordinated assembly of human translation initiation complexes by the hepatitis C virus internal ribosome entry site RNA.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.04.003

Dead-box proteins: a family affair--active and passive players in RNP-remodeling

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.04.003

Passenger-strand cleavage facilitates assembly of siRNA into Ago2-containing RNAi enzyme complexes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.04.003

Argonaute2 cleaves the anti-guide strand of siRNA during RISC activation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.04.003

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.04.003

A role for the P-body component GW182 in microRNA function

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.04.003

Disruption of GW bodies impairs mammalian RNA interference

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.04.003

Translation repression in human cells by microRNA-induced gene silencing requires RCK/p54

7 January 2021

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Regulation by let-7 and lin-4 miRNAs results in target mRNA degradation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.04.003

Identification of novel argonaute-associated proteins

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.04.003

Functional characterization of IRESes by an inhibitor of the RNA helicase eIF4A.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.04.003

Activity of Polyribosomes from the Muscle of Normal and Dystrophic Mice in Cell-Free Amino-Acid Incorporation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.04.003

Translation elongation after assembly of ribosomes on the Cricket paralysis virus internal ribosomal entry site without initiation factors or initiator tRNA.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.04.003

A prokaryotic-like mode of cytoplasmic eukaryotic ribosome binding to the initiation codon during internal translation initiation of hepatitis C and classical swine fever virus RNAs

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.04.003

Canonical eukaryotic initiation factors determine initiation of translation by internal ribosomal entry

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.04.003

Initiation of protein synthesis from the A site of the ribosome

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.04.003

m7GpppG Cap Dependence for Efficient Translation of Drosophila 70-kDa Heat-Shock-Protein (Hsp70) mRNA

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.04.003

Preparation of a cell-free translation system with minimal loss of initiation factor eIF-2/eIF-2B activity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.04.003

Inhibitors of protein synthesis identified by a high throughput multiplexed translation screen

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2007.04.003

10.1016/J.YMETH.2007.04.003

7 January 2021

Identifiers

DOI

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17 August 2017

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