(Q36964574)

17 August 2017

1 reference

title

Effects of Alzheimer's amyloid-beta and tau protein on mitochondrial function -- role of glucose metabolism and insulin signalling (English)

1 reference

17 August 2017

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Anne Eckert

2

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author name string

Virginie Rhein

series ordinal

1

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17 August 2017

1 June 2007

1 reference

Archives of Physiology and Biochemistry

17 August 2017

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17 August 2017

113

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17 August 2017

3

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17 August 2017

131-141

1 reference

Human insulin-degrading enzyme shares structural and functional homologies with E. coli protease III

17 August 2017

1 reference

https://api.crossref.org/works/10.1080%2F13813450701572288

Longitudinal PET Evaluation of Cerebral Metabolic Decline in Dementia: A Potential Outcome Measure in Alzheimer's Disease Treatment Studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450701572288

Diabetes mellitus and risk of Alzheimer disease and decline in cognitive function

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450701572288

Systematic meta-analyses of Alzheimer disease genetic association studies: the AlzGene database

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450701572288

Cerebrometabolic abnormalities in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450701572288

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450701572288

Sequence variants of IDE are associated with the extent of beta-amyloid deposition in the Alzheimer's disease brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450701572288

Sequence variation in the proximity of IDE may impact age at onset of both Parkinson disease and Alzheimer disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450701572288

Neuron-specific apolipoprotein e4 proteolysis is associated with increased tau phosphorylation in brains of transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450701572288

beta-Amyloid fragment 25-35 selectively decreases complex IV activity in isolated mitochondria.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450701572288

Beta-amyloid fragment 25-35 causes mitochondrial dysfunction in primary cortical neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450701572288

Reduced hippocampal insulin-degrading enzyme in late-onset Alzheimer's disease is associated with the apolipoprotein E-epsilon4 allele

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450701572288

Insulin effects on glucose metabolism, memory, and plasma amyloid precursor protein in Alzheimer's disease differ according to apolipoprotein-E genotype.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450701572288

Proteomic and functional analyses reveal a mitochondrial dysfunction in P301L tau transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450701572288

Hippocampal formation glucose metabolism and volume losses in MCI and AD.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450701572288

Type 2 diabetes and atrophy of medial temporal lobe structures on brain MRI.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450701572288

Early regional cerebral glucose hypometabolism in transgenic mice overexpressing the V717F beta-amyloid precursor protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450701572288

Mitochondrial membrane permeabilization and superoxide production during apoptosis. A single-cell analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450701572288

Overexpression of tau protein inhibits kinesin-dependent trafficking of vesicles, mitochondria, and endoplasmic reticulum: implications for Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450701572288

Alzheimer's disease-like alterations in peripheral cells from presenilin-1 transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450701572288

Elevated vulnerability to oxidative stress-induced cell death and activation of caspase-3 by the Swedish amyloid precursor protein mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450701572288

Insulin-degrading enzyme rapidly removes the beta-amyloid precursor protein intracellular domain (AICD)

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450701572288

Insulin-degrading enzyme, apolipoprotein E, and Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450701572288

Insulin degrading enzyme (IDE) genetic variants and risk of Alzheimer's disease: evidence of effect modification by apolipoprotein E (APOE).

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450701572288

beta-Amyloid induces paired helical filament-like tau filaments in tissue culture

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450701572288

Alzheimer's disease: focal cortical changes shown by positron emission tomography.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450701572288

Brain insulin and insulin receptors in aging and sporadic Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450701572288

Does insulin dysfunction play a role in Alzheimer's disease?

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450701572288

Potential roles of insulin and IGF-1 in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450701572288

Brain insulin and feeding: a bi-directional communication

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450701572288

The alpha-ketoglutarate dehydrogenase complex in neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450701572288

Formation of neurofibrillary tangles in P301l tau transgenic mice induced by Abeta 42 fibrils

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450701572288

Type 2 diabetes and cognitive function in community-dwelling elderly women.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450701572288

Soluble protein oligomers in neurodegeneration: lessons from the Alzheimer's amyloid beta-peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450701572288

The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450701572288

Mitochondrial dysfunction in sporadic and genetic Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450701572288

Desensitization of the neuronal insulin receptor: a new approach in the etiopathogenesis of late-onset sporadic dementia of the Alzheimer type (SDAT)?

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450701572288

Insulin and insulin-like growth factor-1 regulate tau phosphorylation in cultured human neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450701572288

The aging brain. Changes in the neuronal insulin/insulin receptor signal transduction cascade trigger late-onset sporadic Alzheimer disease (SAD). A mini-review

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450701572288

The brain insulin signal transduction system and sporadic (type II) Alzheimer disease: an update

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450701572288

Mitochondrial control of neuron death and its role in neurodegenerative disorders.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450701572288

Amyloid beta-induced changes in nitric oxide production and mitochondrial activity lead to apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450701572288

Glucose metabolism in early onset versus late onset Alzheimer's disease: an SPM analysis of 120 patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450701572288

The intracellular domain of the beta-amyloid precursor protein is stabilized by Fe65 and translocates to the nucleus in a notch-like manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450701572288

Brain energy metabolizing enzymes in Alzheimer's disease: alpha-ketoglutarate dehydrogenase complex and cytochrome oxidase

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450701572288

The amyloid precursor protein protects PC12 cells against endoplasmic reticulum stress-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450701572288

Insulin-degrading enzyme: embarking on amyloid destruction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450701572288

Alzheimer's beta-amyloid peptide specifically interacts with and is degraded by insulin degrading enzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450701572288

Association between features of the insulin resistance syndrome and Alzheimer's disease independently of apolipoprotein E4 phenotype: cross sectional population based study

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450701572288

Synaptic targeting by Alzheimer's-related amyloid beta oligomers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450701572288

The risk of dementia among persons with diabetes mellitus: a population-based cohort study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450701572288

Alternative translation initiation generates a novel isoform of insulin-degrading enzyme targeted to mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450701572288

Reduction of trophic support enhances apoptosis in PC12 cells expressing Alzheimer's APP mutation and sensitizes cells to staurosporine-induced cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450701572288

Age at onset in two common neurodegenerative diseases is genetically controlled

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450701572288

ABAD directly links Abeta to mitochondrial toxicity in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450701572288

Glycogen synthase kinase-3 and the Alzheimer-like state of microtubule-associated protein tau.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450701572288

Neurotoxic mechanisms caused by the Alzheimer's disease-linked Swedish amyloid precursor protein mutation: oxidative stress, caspases, and the JNK pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450701572288

Energetics and oxidative stress in synaptic plasticity and neurodegenerative disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450701572288

Degradation of Alzheimer's beta-amyloid protein by human and rat brain peptidases: involvement of insulin-degrading enzyme.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450701572288

Differences of regional cerebral glucose metabolism between presenile and senile dementia of Alzheimer type

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450701572288

Insulin protects against amyloid beta-peptide toxicity in brain mitochondria of diabetic rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450701572288

Susceptibility locus for Alzheimer's disease on chromosome 10.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450701572288

Association of diabetes mellitus and dementia: the Rotterdam Study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450701572288

Diabetes mellitus and the risk of dementia: The Rotterdam Study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450701572288

Electron transport chain defects in Alzheimer's disease brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450701572288

Type 2 diabetes, APOE gene, and the risk for dementia and related pathologies: The Honolulu-Asia Aging Study

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450701572288

Genetic variation in a haplotype block spanningIDE influences Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450701572288

Insulin-degrading enzyme regulates extracellular levels of amyloid beta-protein by degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450701572288

Neurodegenerative disorders associated with diabetes mellitus

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450701572288

Modulation of neurosteroid production in human neuroblastoma cells by Alzheimer's disease key proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450701572288

Impaired Cu/Zn-SOD activity contributes to increased oxidative damage in APP transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450701572288

Decreased pyruvate dehydrogenase complex activity in Huntington and Alzheimer brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450701572288

Tau blocks traffic of organelles, neurofilaments, and APP vesicles in neurons and enhances oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450701572288

Impaired insulin and insulin-like growth factor expression and signaling mechanisms in Alzheimer's disease – is this type 3 diabetes?

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450701572288

Type 2 diabetes mellitus, cognitive impairment and dementia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450701572288

Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450701572288

Differential effects of proteases involved in intracellular degradation of amyloid beta-protein between detergent-soluble and -insoluble pools in CHO-695 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450701572288

Mitochondria in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450701572288

Energy inhibition elevates beta-secretase levels and activity and is potentially amyloidogenic in APP transgenic mice: possible early events in Alzheimer's disease pathogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450701572288

Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450701572288

Modulation of memory by insulin and glucose: neuropsychological observations in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450701572288

Tracking insulin to the mind.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450701572288

Intraneuronal Abeta accumulation precedes plaque formation in beta-amyloid precursor protein and presenilin-1 double-transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450701572288

Diabetes mellitus and risk of dementia in the Kungsholmen project: a 6-year follow-up study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450701572288

Brain insulin receptors and spatial memory. Correlated changes in gene expression, tyrosine phosphorylation, and signaling molecules in the hippocampus of water maze trained rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F13813450701572288

10.1080/13813450701572288

21 January 2018

Identifiers

DOI

1 reference

17 August 2017

1 reference

PubMed ID

17922309