(Q37028788)

17 August 2017

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title

Apoptosis commitment--translating survival signals into decisions on mitochondria (English)

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17 August 2017

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1 reference

James A Keeble

1

1 reference

PubMed ID

18071367

17 August 2017

Andrew P Gilmore

series ordinal

2

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17 August 2017

1 December 2007

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17 August 2017

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17 August 2017

17

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17 August 2017

12

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17 August 2017

976-984

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https://scigraph.springernature.com/pub.10.1038/cr.2007.101

17 August 2017

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cites work

Breaking the mitochondrial barrier

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.101

Apoptotic pathways: ten minutes to dead

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.101

The Bcl2 family: regulators of the cellular life-or-death switch

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.101

Bok is a pro-apoptotic Bcl-2 protein with restricted expression in reproductive tissues and heterodimerizes with selective anti-apoptotic Bcl-2 family members

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.101

Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.101

The combined functions of proapoptotic Bcl-2 family members bak and bax are essential for normal development of multiple tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.101

Bid, Bax, and lipids cooperate to form supramolecular openings in the outer mitochondrial membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.101

BAX-dependent transport of cytochrome c reconstituted in pure liposomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.101

The coordinate release of cytochrome c during apoptosis is rapid, complete and kinetically invariant

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.101

Single-cell fluorescence resonance energy transfer analysis demonstrates that caspase activation during apoptosis is a rapid process. Role of caspase-3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.101

Spatial and temporal changes in Bax subcellular localization during anoikis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.101

Bax and Bak coalesce into novel mitochondria-associated clusters during apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.101

Cytosol-to-membrane redistribution of Bax and Bcl-X(L) during apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.101

Movement of Bax from the cytosol to mitochondria during apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.101

Enforced dimerization of BAX results in its translocation, mitochondrial dysfunction and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.101

Regulated targeting of BAX to mitochondria.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.101

Bid-induced conformational change of Bax is responsible for mitochondrial cytochrome c release during apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.101

Conformation of the Bax C-terminus regulates subcellular location and cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.101

Cell damage-induced conformational changes of the pro-apoptotic protein Bak in vivo precede the onset of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.101

Cell death: critical control points

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.101

Bax is present as a high molecular weight oligomer/complex in the mitochondrial membrane of apoptotic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.101

How do Bax and Bak lead to permeabilization of the outer mitochondrial membrane?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.101

Apoptosis: mitochondrial membrane permeabilization--the (w)hole story?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.101

Tyrosine phosphorylation of paxillin and pp125FAK accompanies cell adhesion to extracellular matrix: a role in cytoskeletal assembly

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.101

Integrin-mediated survival signals regulate the apoptotic function of Bax through its conformation and subcellular localization.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.101

Mitochondria primed by death signals determine cellular addiction to antiapoptotic BCL-2 family members

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.101

Integrins, oncogenes, and anchorage independence.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.101

Control of adhesion-dependent cell survival by focal adhesion kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.101

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.101

Disruption of epithelial cell-matrix interactions induces apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.101

The extracellular matrix as a cell survival factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.101

Integrins: bidirectional, allosteric signaling machines

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.101

Integrin alpha v beta 3 rescues melanoma cells from apoptosis in three-dimensional dermal collagen

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.101

Focal adhesion kinase: the first ten years

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.101

Cell-substrate interactions and signaling through ILK

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.101

Inhibition of pp125FAK in cultured fibroblasts results in apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.101

Extracellular matrix survival signals transduced by focal adhesion kinase suppress p53-mediated apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.101

A role for Jun-N-terminal kinase in anoikis; suppression by bcl-2 and crmA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.101

Matrix adhesion and Ras transformation both activate a phosphoinositide 3-OH kinase and protein kinase B/Akt cellular survival pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.101

Lack of correlation between activation of Jun-NH2-terminal kinase and induction of apoptosis after detachment of epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.101

Matrix survival signaling: from fibronectin via focal adhesion kinase to c-Jun NH(2)-terminal kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.101

The integrin-linked kinase (ILK) suppresses anoikis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.101

Complexity and specificity of integrin signalling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.101

A requirement for caveolin-1 and associated kinase Fyn in integrin signaling and anchorage-dependent cell growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.101

Activation of the ERK1/2 signaling pathway promotes phosphorylation and proteasome-dependent degradation of the BH3-only protein, Bim.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.101

FOXO transcription factors directly activate bim gene expression and promote apoptosis in sympathetic neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.101

Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.101

Activation of BAD by therapeutic inhibition of epidermal growth factor receptor and transactivation by insulin-like growth factor receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.101

Survival factor-mediated BAD phosphorylation raises the mitochondrial threshold for apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.101

PUMA, a novel proapoptotic gene, is induced by p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.101

Suppression of tumorigenesis by the p53 target PUMA

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.101

Integral role of Noxa in p53-mediated apoptotic response

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.101

Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.101

Integrins and EGFR coordinately regulate the pro-apoptotic protein Bim to prevent anoikis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.101

BIM regulates apoptosis during mammary ductal morphogenesis, and its absence reveals alternative cell death mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.101

Overexpression of BAD preferentially augments anoikis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.101

Bmf: a proapoptotic BH3-only protein regulated by interaction with the myosin V actin motor complex, activated by anoikis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.101

Functional role and oncogene-regulated expression of the BH3-only factor Bmf in mammary epithelial anoikis and morphogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.101

Translocation of full-length Bid to mitochondria during anoikis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.101

Bad-deficient mice develop diffuse large B cell lymphoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.101

21 January 2018

At the gates of death.

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.101

BCL-2, BCL-X(L) sequester BH3 domain-only molecules preventing BAX- and BAK-mediated mitochondrial apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.101

Distinct BH3 domains either sensitize or activate mitochondrial apoptosis, serving as prototype cancer therapeutics

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.101

The ErbB signaling network: receptor heterodimerization in development and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.101

Suppression of anoikis and induction of metastasis by the neurotrophic receptor TrkB

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.101

Aberrant activation of notch signaling in human breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.101

Ku70 suppresses the apoptotic translocation of Bax to mitochondria.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.101

Direct activation of Bax by p53 mediates mitochondrial membrane permeabilization and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.101

VDAC2 inhibits BAK activation and mitochondrial apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.101

Myxoma virus M11L blocks apoptosis through inhibition of conformational activation of Bax at the mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.101

An anti-apoptotic viral protein that recruits Bax to mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.101

Cytomegalovirus cell death suppressor vMIA blocks Bax- but not Bak-mediated apoptosis by binding and sequestering Bax at mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.101

Mitochondrial carrier homolog 2 is a target of tBID in cells signaled to die by tumor necrosis factor alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.101

Mitochondrial carrier homolog 2: a clue to cracking the BCL-2 family riddle?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.101

Proapoptotic Bid binds to monolysocardiolipin, a new molecular connection between mitochondrial membranes and cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.101

BAD and glucokinase reside in a mitochondrial complex that integrates glycolysis and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.101

Regulation of MAP Kinase Signaling Modules by Scaffold Proteins in Mammals

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.101

The N-terminal conformation of Bax regulates cell commitment to apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.101

7 January 2021

https://api.crossref.org/works/10.1038%2FCR.2007.101

1 reference

7 January 2021

Hierarchical regulation of mitochondrion-dependent apoptosis by BCL-2 subfamilies

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.101

7 January 2021

Measurement of membrane permeability and permeability transition of mitochondria

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.101

7 January 2021

Phosphorylation and inactivation of BAD by mitochondria-anchored protein kinase A

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.101

7 January 2021

Identifiers

DOI

10.1038/CR.2007.101

1 reference

17 August 2017

1 reference

PubMed ID

18071367