(Q37044669)

17 August 2017

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title

Protein quality control in neurodegeneration: walking the tight rope between health and disease (English)

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17 August 2017

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Hol EM

1

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17 August 2017

Scheper W

series ordinal

2

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17 August 2017

publication date

24 March 2007

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Journal of Molecular Neuroscience

17 August 2017

published in

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17 August 2017

volume

34

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17 August 2017

issue

1

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17 August 2017

page(s)

23-33

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https://scigraph.springernature.com/pub.10.1007/s12031-007-0013-8

17 August 2017

exact match

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cites work

Transcriptional regulation by the proteasome as a mechanism for cellular protein homeostasis

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https://api.crossref.org/works/10.1007%2FS12031-007-0013-8

Expression of heat shock proteins in Alzheimer's disease

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The proteasome in Alzheimer's disease and Parkinson's disease: lessons from ubiquitin B+1.

21 January 2018

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Molecular chaperones in protein quality control

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https://api.crossref.org/works/10.1007%2FS12031-007-0013-8

Extensive involvement of autophagy in Alzheimer disease: an immuno-electron microscopy study.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12031-007-0013-8

Accumulation of mutant huntingtin fragments in aggresome-like inclusion bodies as a result of insufficient protein degradation

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https://api.crossref.org/works/10.1007%2FS12031-007-0013-8

Activation of the unfolded protein response in Parkinson's disease

21 January 2018

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12 December 2020

Protein degradation and protection against misfolded or damaged proteins

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12 December 2020

Geldanamycin activates a heat shock response and inhibits huntingtin aggregation in a cell culture model of Huntington's disease

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12 December 2020

Neuronal dysfunction in a polyglutamine disease model occurs in the absence of ubiquitin-proteasome system impairment and inversely correlates with the degree of nuclear inclusion formation

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12 December 2020

Pael receptor, endoplasmic reticulum stress, and Parkinson?s disease

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12 December 2020

Treatment with arimoclomol, a coinducer of heat shock proteins, delays disease progression in ALS mice

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12 December 2020

Proteasomal inhibition by misfolded mutant superoxide dismutase 1 induces selective motor neuron death in familial amyotrophic lateral sclerosis

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12 December 2020

Autophagy in neurodegenerative disease: friend, foe or turncoat?

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12 December 2020

Ubiquitin and protein turnover in synapse function

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12 December 2020

Protein quality control in Alzheimer's disease: a fatal saviour

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12 December 2020

The unfolded protein response is activated in Alzheimer's disease.

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12 December 2020

Endoplasmic reticulum stress triggers autophagy

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12 December 2020

Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta

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12 December 2020

The mammalian unfolded protein response

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12 December 2020

ATF3 expression precedes death of spinal motoneurons in amyotrophic lateral sclerosis-SOD1 transgenic mice and correlates with c-Jun phosphorylation, CHOP expression, somato-dendritic ubiquitination and Golgi fragmentation

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12 December 2020

Transmission of proteotoxicity across cellular compartments

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12 December 2020

LHS1 and SIL1 provide a lumenal function that is essential for protein translocation into the endoplasmic reticulum

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12 December 2020

HDAC6 and microtubules are required for autophagic degradation of aggregated huntingtin

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12 December 2020

Evidence for a COP-I-independent transport route from the Golgi complex to the endoplasmic reticulum

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12 December 2020

Accumulation of aberrant ubiquitin induces aggregate formation and cell death in polyglutamine diseases

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12 December 2020

Caspase-12 cleavage and increased oxidative stress during motoneuron degeneration in transgenic mouse model of ALS.

1 reference

12 December 2020

Rab6 is increased in Alzheimer's disease brain and correlates with endoplasmic reticulum stress

1 reference

12 December 2020

Reduction of calcium release from the endoplasmic reticulum could only provide partial neuroprotection against beta-amyloid peptide toxicity.

1 reference

12 December 2020

Aggresomes: a cellular response to misfolded proteins

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12 December 2020

The molecular chaperone alphaB-crystallin enhances amyloid beta neurotoxicity

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12 December 2020

Autophagy, proteasomes, lipofuscin, and oxidative stress in the aging brain.

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12 December 2020

Proteasome inhibitor-induced model of Parkinson's disease

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12 December 2020

The highways and byways of prion protein trafficking

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12 December 2020

Systemic exposure to proteasome inhibitors causes a progressive model of Parkinson's disease

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12 December 2020

Biochemical, ultrastructural, and reversibility studies on huntingtin filaments isolated from mouse and human brain.

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12 December 2020

Upstream signaling pathways leading to the activation of double-stranded RNA-dependent serine/threonine protein kinase in beta-amyloid peptide neurotoxicity

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12 December 2020

Endoplasmic reticulum stress triggers an acute proteasome-dependent degradation of ATF6.

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12 December 2020

Detergent-resistant membrane domains but not the proteasome are involved in the misfolding of a PrP mutant retained in the endoplasmic reticulum

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12 December 2020

A regulatory link between ER-associated protein degradation and the unfolded-protein response

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12 December 2020

OASIS, a CREB/ATF-family member, modulates UPR signalling in astrocytes

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12 December 2020

Endoplasmic reticulum stress and the unfolded protein response in cellular models of Parkinson's disease.

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12 December 2020

A selective inhibitor of eIF2alpha dephosphorylation protects cells from ER stress

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12 December 2020

Regulating the regulators: control of protein ubiquitination and ubiquitin-like modifications by extracellular stimuli

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12 December 2020

CHOP is implicated in programmed cell death in response to impaired function of the endoplasmic reticulum

1 reference

12 December 2020

Aggresomes, inclusion bodies and protein aggregation

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12 December 2020

Lewy-body formation is an aggresome-related process: a hypothesis

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12 December 2020

Ubiquitin proteasome system as a pharmacological target in neurodegeneration.

1 reference

12 December 2020

Frameshift mutants of beta amyloid precursor protein and ubiquitin-B in Alzheimer's and Down patients

1 reference

12 December 2020

Ubiquitin-immunoreactive intraneuronal inclusions in amyotrophic lateral sclerosis. Morphology, distribution, and specificity.

1 reference

12 December 2020

Induction of the unfolded protein response in familial amyotrophic lateral sclerosis and association of protein-disulfide isomerase with superoxide dismutase 1.

1 reference

12 December 2020

Cytosol-endoplasmic reticulum interplay by Sec61alpha translocon in polyglutamine-mediated neurotoxicity in Drosophila

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12 December 2020

Autophagy in cell death: an innocent convict?

1 reference

12 December 2020

Stress proteins in neural cells: functional roles in health and disease

1 reference

12 December 2020

Apoptosis and autophagy in nigral neurons of patients with Parkinson's disease.

1 reference

12 December 2020

Conversion of PrP to a self-perpetuating PrPSc-like conformation in the cytosol

1 reference

12 December 2020

Impairment of the ubiquitin-proteasome system by protein aggregation

1 reference

12 December 2020

ASK1 is essential for endoplasmic reticulum stress-induced neuronal cell death triggered by expanded polyglutamine repeats

1 reference

12 December 2020

Increased susceptibility of cytoplasmic over nuclear polyglutamine aggregates to autophagic degradation

1 reference

12 December 2020

Rab6 coordinates a novel Golgi to ER retrograde transport pathway in live cells

1 reference

12 December 2020

How the ubiquitin-proteasome system controls transcription

1 reference

12 December 2020

Abeta immunotherapy leads to clearance of early, but not late, hyperphosphorylated tau aggregates via the proteasome

1 reference

12 December 2020

The ubiquitin system for protein degradation and some of its roles in the control of the cell-division cycle (Nobel lecture).

1 reference

12 December 2020

Down regulation of DJ-1 enhances cell death by oxidative stress, ER stress, and proteasome inhibition

1 reference

12 December 2020

Ubiquitin immunocytochemistry in human spongiform encephalopathies.

1 reference

12 December 2020

Proteasomes and their kin: proteases in the machine age

1 reference

12 December 2020

Endoplasmic reticulum-localized amyloid beta-peptide is degraded in the cytosol by two distinct degradation pathways

1 reference

12 December 2020

Protein quality control in Alzheimer's disease by the ubiquitin proteasome system.

1 reference

12 December 2020

'Unfolding' pathways in neurodegenerative disease

1 reference

12 December 2020

Autophagy is a part of ultrastructural synaptic pathology in Creutzfeldt-Jakob disease: a brain biopsy study

1 reference

12 December 2020

Involvement of caspase-4 in endoplasmic reticulum stress-induced apoptosis and Abeta-induced cell death

1 reference

12 December 2020

Delivery of ubiquitinated substrates to protein-unfolding machines

1 reference

12 December 2020

Abeta 1-42 induces mild endoplasmic reticulum stress in an aggregation state-dependent manner.

1 reference

12 December 2020

ERAD: the long road to destruction

1 reference

12 December 2020

Autophagy is activated for cell survival after endoplasmic reticulum stress

1 reference

12 December 2020

Autophagy in neurons: a review

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12 December 2020

Endoplasmic reticulum stress features are prominent in Alzheimer disease but not in prion diseases in vivo

1 reference

12 December 2020

Protein accumulation and neurodegeneration in the woozy mutant mouse is caused by disruption of SIL1, a cochaperone of BiP

1 reference

12 December 2020

Recognition of the polyubiquitin proteolytic signal

1 reference

12 December 2020

The unfolded protein response modulates toxicity of the expanded glutamine androgen receptor

1 reference

12 December 2020

Alpha-synuclein blocks ER-Golgi traffic and Rab1 rescues neuron loss in Parkinson's models

1 reference

12 December 2020

Polyglutamine aggregates stimulate ER stress signals and caspase-12 activation

1 reference

12 December 2020

Fibroblasts from FAD-linked presenilin 1 mutations display a normal unfolded protein response but overproduce Abeta42 in response to tunicamycin

1 reference

12 December 2020

Differential effects of a Rab6 mutant on secretory versus amyloidogenic processing of Alzheimer's beta-amyloid precursor protein

1 reference

12 December 2020

Proteasome inhibitors disrupt the unfolded protein response in myeloma cells

1 reference

12 December 2020

Caspase-12 and endoplasmic reticulum stress mediate neurotoxicity of pathological prion protein.

1 reference

12 December 2020

Autophagic vacuoles are enriched in amyloid precursor protein-secretase activities: implications for beta-amyloid peptide over-production and localization in Alzheimer's disease

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12 December 2020

Beta-amyloid peptides induces neuronal apoptosis via a mechanism independent of unfolded protein responses.

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12 December 2020

A new pharmacology--drugging stressed folding pathways.

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12 December 2020

Heat shock proteins as emerging therapeutic targets

1 reference

12 December 2020

Stimulation of PrP(C) retrograde transport toward the endoplasmic reticulum increases accumulation of PrP(Sc) in prion-infected cells

1 reference

12 December 2020

Secretory pathway quality control operating in Golgi, plasmalemmal, and endosomal systems

1 reference

12 December 2020

Ubiquitin-binding domains

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12 December 2020

The disulfide isomerase Grp58 is a protective factor against prion neurotoxicity.

1 reference

12 December 2020

Conditions of endoplasmic reticulum stress favor the accumulation of cytosolic prion protein

1 reference

12 December 2020

The endoplasmic reticulum stress-responsive protein GRP78 protects neurons against excitotoxicity and apoptosis: suppression of oxidative stress and stabilization of calcium homeostasis

1 reference

12 December 2020

The unfolded protein response regulates multiple aspects of secretory and membrane protein biogenesis and endoplasmic reticulum quality control

1 reference

12 December 2020

Protein retention in the endoplasmic reticulum, blockade of programmed cell death and autophagy selectively occur in spinal cord motoneurons after glutamate receptor-mediated injury.

1 reference

12 December 2020

A series of ubiquitin binding factors connects CDC48/p97 to substrate multiubiquitylation and proteasomal targeting

1 reference

12 December 2020

An unfolded putative transmembrane polypeptide, which can lead to endoplasmic reticulum stress, is a substrate of Parkin

1 reference

12 December 2020

Activation of chaperone-mediated autophagy during oxidative stress

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12 December 2020

Autophagosomes: biogenesis from scratch?

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12 December 2020

Neurotoxicity and neurodegeneration when PrP accumulates in the cytosol

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12 December 2020

Regulated protein degradation

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12 December 2020

Endoplasmic reticulum stress compromises the ubiquitin-proteasome system

1 reference

12 December 2020

Intracellular re-routing of prion protein prevents propagation of PrP(Sc) and delays onset of prion disease

1 reference

12 December 2020

Mutant SOD1 linked to familial amyotrophic lateral sclerosis, but not wild-type SOD1, induces ER stress in COS7 cells and transgenic mice.

1 reference

12 December 2020

Macroautophagy--a novel Beta-amyloid peptide-generating pathway activated in Alzheimer's disease

1 reference

12 December 2020

Hsp70 chaperones: cellular functions and molecular mechanism

1 reference

12 December 2020

CHIP is associated with Parkin, a gene responsible for familial Parkinson's disease, and enhances its ubiquitin ligase activity

1 reference

12 December 2020

CHIP promotes proteasomal degradation of familial ALS-linked mutant SOD1 by ubiquitinating Hsp/Hsc70.

1 reference

12 December 2020

Ubiquitin-mediated proteolysis centers in HeLa cells: indication from studies of an inhibitor of the chymotrypsin-like activity of the proteasome

1 reference

12 December 2020

10.1007/S12031-007-0013-8

Identifiers

DOI

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17 August 2017

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