(Q37102533)

18 August 2017

cis-Delta(2,3)-double bond of phoslactomycins is generated by a post-PKS tailoring enzyme (English)

1 reference

18 August 2017

2

Mamoun M Alhamadsheh

1 reference

18 August 2017

Nadaraj Palaniappan

1

1 reference

18 August 2017

Kevin A Reynolds

series ordinal

3

1 reference

18 August 2017

language of work or name

English

0 references

publication date

21 August 2008

1 reference

Journal of the American Chemical Society

18 August 2017

1 reference

18 August 2017

130

1 reference

18 August 2017

37

1 reference

18 August 2017

12236-12237

1 reference

Modular polyketide synthases and cis double bond formation: establishment of activated cis-3-cyclohexylpropenoic acid as the diketide intermediate in phoslactomycin biosynthesis

18 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2644895

Total synthesis and evaluation of cytostatin, its C10-C11 diastereomers, and additional key analogues: impact on PP2A inhibition

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2644895

Genetic manipulation of the biosynthetic process leading to phoslactomycins, potent protein phosphatase 2A inhibitors.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2644895

The plmS2-encoded cytochrome P450 monooxygenase mediates hydroxylation of phoslactomycin B in Streptomyces sp. strain HK803.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2644895

Polyketide biosynthesis: a millennium review

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2644895

Novel antitumor agents CI-920, PD 113,270 and PD 113,271. II. Isolation and characterization

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2644895

Studies on new phosphate ester antifungal antibiotics phoslactomycins. I. Taxonomy, fermentation, purification and biological activities

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2644895

Phoslactomycin targets cysteine-269 of the protein phosphatase 2A catalytic subunit in cells

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2644895

Polyketide double bond biosynthesis. Mechanistic analysis of the dehydratase-containing module 2 of the picromycin/methymycin polyketide synthase

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2644895

Studies on new phosphate ester antifungal antibiotics phoslactomycins. II. Structure elucidation of phoslactomycins A to F.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2644895

The leptomycin gene cluster and its heterologous expression in Streptomyces lividans

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2644895

A pH-stability study of phoslactomycin B and analysis of the acid and base degradation products

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2644895

Conserved amino acid residues correlating with ketoreductase stereospecificity in modular polyketide synthases

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2644895

Enhancement and selective production of phoslactomycin B, a protein phosphatase IIa inhibitor, through identification and engineering of the corresponding biosynthetic gene cluster

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2644895

A model of structure and catalysis for ketoreductase domains in modular polyketide synthases

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2644895

An unexpected interaction between the modular polyketide synthases, erythromycin DEBS1 and pikromycin PikAIV, leads to efficient triketide lactone synthesis

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2644895

Isolation and characterization of a new antibiotic, malolactomycin A

3 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18714992

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Structural studies of new macrolide antibiotics, shurimycins A and B

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18714992

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Azalomycin F complex from Streptomyces hygroscopicus, MSU/MN-4-75B

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18714992

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Pironetin, a Novel Plant Growth Regulator Produced by Streptomyces sp. NK10958 III. Biosynthesis.

1 reference

12 April 2024

https://opencitations.net/index/api/v1/citations/10.7164/ANTIBIOTICS.48.896

Identifiers

DOI

10.1021/JA8044162

1 reference

18 August 2017

1 reference

18 August 2017

PubMed publication ID

18714992

1 reference