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SHP-2 tyrosine phosphatase in human diseases.
scientific article published on 30 January 2009
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stated in
Europe PubMed Central
PMC publication ID
2680053
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19436828%20AND%20SRC:MED&resulttype=core&format=json
retrieved
28 January 2020
review article
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stated in
Europe PubMed Central
title
SHP-2 tyrosine phosphatase in human diseases
(English)
1 reference
stated in
Europe PubMed Central
PMC publication ID
2680053
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19436828%20AND%20SRC:MED&resulttype=core&format=json
retrieved
28 January 2020
author name string
Hong Zheng
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMC publication ID
2680053
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19436828%20AND%20SRC:MED&resulttype=core&format=json
retrieved
28 January 2020
Shawn Alter
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMC publication ID
2680053
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19436828%20AND%20SRC:MED&resulttype=core&format=json
retrieved
28 January 2020
Cheng-Kui Qu
series ordinal
3
1 reference
stated in
Europe PubMed Central
PMC publication ID
2680053
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19436828%20AND%20SRC:MED&resulttype=core&format=json
retrieved
28 January 2020
publication date
30 January 2009
1 reference
stated in
Europe PubMed Central
PMC publication ID
2680053
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19436828%20AND%20SRC:MED&resulttype=core&format=json
retrieved
28 January 2020
published in
International Journal of Clinical and Experimental Medicine
1 reference
stated in
Europe PubMed Central
PMC publication ID
2680053
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19436828%20AND%20SRC:MED&resulttype=core&format=json
retrieved
28 January 2020
volume
2
1 reference
stated in
Europe PubMed Central
PMC publication ID
2680053
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19436828%20AND%20SRC:MED&resulttype=core&format=json
retrieved
28 January 2020
issue
1
1 reference
stated in
Europe PubMed Central
PMC publication ID
2680053
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19436828%20AND%20SRC:MED&resulttype=core&format=json
retrieved
28 January 2020
page(s)
17-25
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Europe PubMed Central
PMC publication ID
2680053
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19436828%20AND%20SRC:MED&resulttype=core&format=json
retrieved
28 January 2020
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Functional analysis of leukemia-associated PTPN11 mutations in primary hematopoietic cells
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Human somatic PTPN11 mutations induce hematopoietic-cell hypersensitivity to granulocyte-macrophage colony-stimulating factor
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Tyrosine phosphatase activity in mitochondria: presence of Shp-2 phosphatase in mitochondria
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Mouse model of Noonan syndrome reveals cell type- and gene dosage-dependent effects of Ptpn11 mutation
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DNA damage-induced G2/M checkpoint in SV40 large T antigen-immortalized embryonic fibroblast cells requires SHP-2 tyrosine phosphatase
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Role of SHP-2 tyrosine phosphatase in the DNA damage-induced cell death response
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Prolactin induces SHP-2 association with Stat5, nuclear translocation, and binding to the beta-casein gene promoter in mammary cells
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Cytosolic tyrosine dephosphorylation of STAT5. Potential role of SHP-2 in STAT5 regulation
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Biased suppression of hematopoiesis and multiple developmental defects in chimeric mice containing Shp-2 mutant cells
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6 September 2017
Crystal structure of the tyrosine phosphatase SHP-2
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A deletion mutation in the SH2-N domain of Shp-2 severely suppresses hematopoietic cell development
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6 September 2017
Abnormal mesoderm patterning in mouse embryos mutant for the SH2 tyrosine phosphatase Shp-2.
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6 September 2017
A new function for a phosphotyrosine phosphatase: linking GRB2-Sos to a receptor tyrosine kinase
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6 September 2017
Protein-tyrosine-phosphatase SHPTP2 couples platelet-derived growth factor receptor beta to Ras
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6 September 2017
Nuclear protein tyrosine phosphatase Shp-2 is one important negative regulator of nuclear export of telomerase reverse transcriptase.
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Isolation of a distinct class of gain-of-function SHP-2 mutants with oncogenic RAS-like transforming activity from solid tumors
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SOS1 mutations are rare in human malignancies: implications for Noonan Syndrome patients
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14 September 2017
SHP-2-dependent mitogen-activated protein kinase activation regulates EGFRvIII but not wild-type epidermal growth factor receptor phosphorylation and glioblastoma cell survival
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14 September 2017
Noonan syndrome-associated SHP2/PTPN11 mutants cause EGF-dependent prolonged GAB1 binding and sustained ERK2/MAPK1 activation
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14 September 2017
Catalytic-dependent and -independent roles of SHP-2 tyrosine phosphatase in interleukin-3 signaling
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14 September 2017
Noonan syndrome. An update and review for the primary pediatrician
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14 September 2017
Insulin signaling in mice expressing reduced levels of Syp.
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28 September 2017
Diverse biochemical properties of Shp2 mutants. Implications for disease phenotypes
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26 June 2018
Blocking the function of tyrosine phosphatase SHP-2 by targeting its Src homology 2 domains
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2680053
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26 June 2018
Revealing mechanisms for SH2 domain mediated regulation of the protein tyrosine phosphatase SHP-2.
1 reference
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PubMed Central
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26 June 2018
Common acute lymphoblastic leukemia in a girl with genetically confirmed LEOPARD syndrome
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PubMed Central
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3 September 2018
Role of SHP2 for FLT3-dependent proliferation and transformation in 32D cells
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PubMed Central
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3 September 2018
Gain-of-function SOS1 mutations cause a distinctive form of Noonan syndrome.
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3 September 2018
An Shp2/SFK/Ras/Erk signaling pathway controls trophoblast stem cell survival
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3 September 2018
Effects of a leukemia-associated gain-of-function mutation of SHP-2 phosphatase on interleukin-3 signaling
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PubMed Central
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3 September 2018
SHP-2 phosphatase regulates DNA damage-induced apoptosis and G2/M arrest in catalytically dependent and independent manners, respectively
1 reference
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PubMed Central
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3 September 2018
Prognostic, therapeutic, and mechanistic implications of a mouse model of leukemia evoked by Shp2 (PTPN11) mutations.
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3 September 2018
A negative role of SHP-2 tyrosine phosphatase in growth factor-dependent hematopoietic cell survival
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PubMed Central
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3 September 2018
Genetic evidence for lineage-related and differentiation stage-related contribution of somatic PTPN11 mutations to leukemogenesis in childhood acute leukemia
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3 September 2018
Mutations in PTPN11 implicate the SHP-2 phosphatase in leukemogenesis
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3 September 2018
Somatic mutations in PTPN11 in juvenile myelomonocytic leukemia, myelodysplastic syndromes and acute myeloid leukemia
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3 September 2018
Identification of Shp-2 as a Stat5A phosphatase
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3 September 2018
PTPN11 mutations in LEOPARD syndrome
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PubMed Central
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3 September 2018
Expression of a dominant negative SHP-2 in transgenic mice induces insulin resistance.
1 reference
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PubMed Central
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3 September 2018
The Tyrosine Phosphatase Shp2 Interacts with NPM-ALK and Regulates Anaplastic Lymphoma Cell Growth and Migration
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2680053
retrieved
4 December 2018
Increased susceptibility to ischemia-induced brain damage in transgenic mice overexpressing a dominant negative form of SHP2
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/19436828
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
PMC publication ID
2680053
1 reference
stated in
Europe PubMed Central
PMC publication ID
2680053
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19436828%20AND%20SRC:MED&resulttype=core&format=json
retrieved
28 January 2020
PubMed publication ID
19436828
1 reference
stated in
Europe PubMed Central
PMC publication ID
2680053
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19436828%20AND%20SRC:MED&resulttype=core&format=json
retrieved
28 January 2020
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