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Sirtuins in neurodegenerative diseases: an update on potential mechanisms.
scientific article published on 25 September 2013
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scholarly article
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Europe PubMed Central
PMC publication ID
3782645
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24093018%20AND%20SRC:MED&resulttype=core&format=json
retrieved
26 February 2020
title
Sirtuins in neurodegenerative diseases: an update on potential mechanisms
(English)
1 reference
stated in
Europe PubMed Central
PMC publication ID
3782645
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24093018%20AND%20SRC:MED&resulttype=core&format=json
retrieved
26 February 2020
main subject
neurodegeneration
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based on heuristic
inferred from title
author
Raymond A Swanson
series ordinal
4
1 reference
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Europe PubMed Central
PMC publication ID
3782645
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24093018%20AND%20SRC:MED&resulttype=core&format=json
retrieved
26 February 2020
author name string
Sang-Won Min
series ordinal
1
1 reference
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Europe PubMed Central
PMC publication ID
3782645
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24093018%20AND%20SRC:MED&resulttype=core&format=json
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26 February 2020
Peter D Sohn
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2
1 reference
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Europe PubMed Central
PMC publication ID
3782645
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24093018%20AND%20SRC:MED&resulttype=core&format=json
retrieved
26 February 2020
Seo-Hyun Cho
series ordinal
3
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Europe PubMed Central
PMC publication ID
3782645
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24093018%20AND%20SRC:MED&resulttype=core&format=json
retrieved
26 February 2020
Li Gan
series ordinal
5
1 reference
stated in
Europe PubMed Central
PMC publication ID
3782645
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24093018%20AND%20SRC:MED&resulttype=core&format=json
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26 February 2020
publication date
25 September 2013
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stated in
Europe PubMed Central
PMC publication ID
3782645
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24093018%20AND%20SRC:MED&resulttype=core&format=json
retrieved
26 February 2020
published in
Frontiers in Aging Neuroscience
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stated in
Europe PubMed Central
PMC publication ID
3782645
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24093018%20AND%20SRC:MED&resulttype=core&format=json
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26 February 2020
volume
5
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Europe PubMed Central
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3782645
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retrieved
26 February 2020
page(s)
53
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Europe PubMed Central
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3782645
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24093018%20AND%20SRC:MED&resulttype=core&format=json
retrieved
26 February 2020
cites work
Dual control of mitochondrial biogenesis by sirtuin 1 and sirtuin 3.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3782645
retrieved
6 September 2017
SIRT1 and SIRT2: emerging targets in neurodegeneration
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3782645
retrieved
6 September 2017
Regulated transcription of human matrix metalloproteinase 13 (MMP13) and interleukin-1β (IL1B) genes in chondrocytes depends on methylation of specific proximal promoter CpG sites
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3782645
retrieved
6 September 2017
Argyrophilic grain disease differs from other tauopathies by lacking tau acetylation.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3782645
retrieved
6 September 2017
Crosstalk between poly(ADP-ribose) polymerase and sirtuin enzymes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3782645
retrieved
6 September 2017
Deciphering the mechanism underlying late-onset Alzheimer disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3782645
retrieved
6 September 2017
Variant of TREM2 Associated with the Risk of Alzheimer's Disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3782645
retrieved
6 September 2017
CNS SIRT3 expression is altered by reactive oxygen species and in Alzheimer's disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3782645
retrieved
6 September 2017
Mitochondrial protein acylation and intermediary metabolism: regulation by sirtuins and implications for metabolic disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3782645
retrieved
6 September 2017
Metabolic and neuropsychiatric effects of calorie restriction and sirtuins
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3782645
retrieved
6 September 2017
Regulation of chromatin structure by poly(ADP-ribosyl)ation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3782645
retrieved
6 September 2017
MicroRNAs in learning, memory, and neurological diseases
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3782645
retrieved
6 September 2017
SIRT2 interferes with autophagy-mediated degradation of protein aggregates in neuronal cells under proteasome inhibition
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3782645
retrieved
6 September 2017
SIRT1-mediated deacetylation of MeCP2 contributes to BDNF expression
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3782645
retrieved
6 September 2017
Are sirtuins viable targets for improving healthspan and lifespan?
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3782645
retrieved
6 September 2017
trans-(-)-ε-Viniferin increases mitochondrial sirtuin 3 (SIRT3), activates AMP-activated protein kinase (AMPK), and protects cells in models of Huntington Disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3782645
retrieved
6 September 2017
Autophagy induced by the class III histone deacetylase Sirt1 prevents prion peptide neurotoxicity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3782645
retrieved
6 September 2017
The sirtuin SIRT6 regulates lifespan in male mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3782645
retrieved
6 September 2017
Acetylated tau, a novel pathological signature in Alzheimer's disease and other tauopathies
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3782645
retrieved
6 September 2017
NF-κB, the first quarter-century: remarkable progress and outstanding questions
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3782645
retrieved
6 September 2017
Emerging roles of SIRT6 on telomere maintenance, DNA repair, metabolism and mammalian aging
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3782645
retrieved
6 September 2017
Inflammation, DNA methylation and colitis-associated cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3782645
retrieved
6 September 2017
SIRT1 protects against α-synuclein aggregation by activating molecular chaperones
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3782645
retrieved
6 September 2017
A role for neuronal cAMP responsive-element binding (CREB)-1 in brain responses to calorie restriction
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3782645
retrieved
6 September 2017
Sirt1 mediates neuroprotection from mutant huntingtin by activation of the TORC1 and CREB transcriptional pathway
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3782645
retrieved
6 September 2017
Proatherogenic abnormalities of lipid metabolism in SirT1 transgenic mice are mediated through Creb deacetylation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3782645
retrieved
6 September 2017
Sirt5 is a NAD-dependent protein lysine demalonylase and desuccinylase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3782645
retrieved
6 September 2017
SIRT1 deacetylates the DNA methyltransferase 1 (DNMT1) protein and alters its activities
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3782645
retrieved
6 September 2017
Absence of effects of Sir2 overexpression on lifespan in C. elegans and Drosophila
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3782645
retrieved
6 September 2017
Regulation of Caenorhabditis elegans lifespan by sir-2.1 transgenes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3782645
retrieved
6 September 2017
Resveratrol-activated AMPK/SIRT1/autophagy in cellular models of Parkinson's disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3782645
retrieved
6 September 2017
Epigenetic mechanisms in cognition
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3782645
retrieved
6 September 2017
Epigenetics, bioenergetics, and microRNA coordinate gene-specific reprogramming during acute systemic inflammation.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3782645
retrieved
6 September 2017
PARP-1 inhibition increases mitochondrial metabolism through SIRT1 activation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3782645
retrieved
6 September 2017
The acetylation of tau inhibits its function and promotes pathological tau aggregation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3782645
retrieved
6 September 2017
Neuronal Sirt3 protects against excitotoxic injury in mouse cortical neuron culture
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3782645
retrieved
6 September 2017
NAD+-dependent SIRT1 deacetylase participates in epigenetic reprogramming during endotoxin tolerance
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3782645
retrieved
6 September 2017
Calorie restriction reduces oxidative stress by SIRT3-mediated SOD2 activation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3782645
retrieved
6 September 2017
Sirt3 mediates reduction of oxidative damage and prevention of age-related hearing loss under caloric restriction
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3782645
retrieved
6 September 2017
Acetylation of tau inhibits its degradation and contributes to tauopathy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3782645
retrieved
6 September 2017
Sirtuin regulation of mitochondria: energy production, apoptosis, and signaling
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3782645
retrieved
6 September 2017
SIRT1 suppresses beta-amyloid production by activating the alpha-secretase gene ADAM10.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3782645
retrieved
6 September 2017
Myeloid deletion of SIRT1 induces inflammatory signaling in response to environmental stress.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3782645
retrieved
6 September 2017
A novel pathway regulates memory and plasticity via SIRT1 and miR-134
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3782645
retrieved
6 September 2017
The genetics of ageing
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3782645
retrieved
6 September 2017
Mechanisms underlying inflammation in neurodegeneration
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3782645
retrieved
6 September 2017
Alzheimer's Disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3782645
retrieved
6 September 2017
Transcriptional control of the inflammatory response
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3782645
retrieved
6 September 2017
SIRT1 controls the transcription of the peroxisome proliferator-activated receptor-gamma Co-activator-1alpha (PGC-1alpha) gene in skeletal muscle through the PGC-1alpha autoregulatory loop and interaction with MyoD.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3782645
retrieved
6 September 2017
SIRT1 promotes cell survival under stress by deacetylation-dependent deactivation of poly(ADP-ribose) polymerase 1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3782645
retrieved
6 September 2017
Tauopathies with parkinsonism: clinical spectrum, neuropathologic basis, biological markers, and treatment options.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3782645
retrieved
6 September 2017
Stress-inducible regulation of heat shock factor 1 by the deacetylase SIRT1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3782645
retrieved
6 September 2017
SIRT6 links histone H3 lysine 9 deacetylation to NF-kappaB-dependent gene expression and organismal life span
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3782645
retrieved
6 September 2017
Sirtuin 1 reduction parallels the accumulation of tau in Alzheimer disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3782645
retrieved
6 September 2017
C. elegans model identifies genetic modifiers of alpha-synuclein inclusion formation during aging
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3782645
retrieved
6 September 2017
A role for the NAD-dependent deacetylase Sirt1 in the regulation of autophagy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3782645
retrieved
6 September 2017
Autophagy in the Pathogenesis of Disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3782645
retrieved
6 September 2017
Brain-derived neurotrophic factor in neuronal survival and behavior-related plasticity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3782645
retrieved
6 September 2017
Motif module map reveals enforcement of aging by continual NF-kappaB activity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3782645
retrieved
6 September 2017
SIRT1 regulates the histone methyl-transferase SUV39H1 during heterochromatin formation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3782645
retrieved
6 September 2017
Mammalian Sir2 homolog SIRT3 regulates global mitochondrial lysine acetylation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3782645
retrieved
6 September 2017
Sirtuin 2 inhibitors rescue alpha-synuclein-mediated toxicity in models of Parkinson's disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3782645
retrieved
6 September 2017
Neuropathologic diagnostic and nosologic criteria for frontotemporal lobar degeneration: consensus of the Consortium for Frontotemporal Lobar Degeneration
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3782645
retrieved
6 September 2017
Recovery of learning and memory is associated with chromatin remodelling
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3782645
retrieved
6 September 2017
Sirtuins in mammals: insights into their biological function
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3782645
retrieved
6 September 2017
The mammalian epigenome
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3782645
retrieved
6 September 2017
Inflammaging and anti-inflammaging: a systemic perspective on aging and longevity emerged from studies in humans
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3782645
retrieved
6 September 2017
Suppression of reactive oxygen species and neurodegeneration by the PGC-1 transcriptional coactivators
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3782645
retrieved
6 September 2017
Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3782645
retrieved
6 September 2017
Neuronal SIRT1 activation as a novel mechanism underlying the prevention of Alzheimer disease amyloid neuropathology by calorie restriction
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3782645
retrieved
6 September 2017
Mammalian Sir2 homolog SIRT7 is an activator of RNA polymerase I transcription
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3782645
retrieved
6 September 2017
A specific amyloid-beta protein assembly in the brain impairs memory
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3782645
retrieved
6 September 2017
Roles for NF-kappaB in nerve cell survival, plasticity, and disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3782645
retrieved
6 September 2017
Resveratrol rescues mutant polyglutamine cytotoxicity in nematode and mammalian neurons.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3782645
retrieved
6 September 2017
Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3782645
retrieved
6 September 2017
Twenty years of the Alzheimer's disease amyloid hypothesis: a genetic perspective
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3782645
retrieved
6 September 2017
Redox regulation of NF-kappaB activation: distinct redox regulation between the cytoplasm and the nucleus
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3782645
retrieved
6 September 2017
Sir2 mediates longevity in the fly through a pathway related to calorie restriction
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3782645
retrieved
6 September 2017
Oxidative stress in neurodegeneration: cause or consequence?
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3782645
retrieved
6 September 2017
Glutamate-mediated excitotoxicity and neurodegeneration in Alzheimer's disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3782645
retrieved
6 September 2017
Gene regulation and DNA damage in the ageing human brain
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3782645
retrieved
6 September 2017
Modulation of NF-kappaB-dependent transcription and cell survival by the SIRT1 deacetylase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3782645
retrieved
6 September 2017
Regulation of distinct biological activities of the NF-kappaB transcription factor complex by acetylation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3782645
retrieved
6 September 2017
Dynamic changes in histone H3 Lys 9 methylation occurring at tightly regulated inducible inflammatory genes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3782645
retrieved
6 September 2017
Abeta toxicity in Alzheimer's disease: globular oligomers (ADDLs) as new vaccine and drug targets
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3782645
retrieved
6 September 2017
The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3782645
retrieved
6 September 2017
Genomic profiling of short- and long-term caloric restriction effects in the liver of aging mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3782645
retrieved
6 September 2017
Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3782645
retrieved
6 September 2017
Phylogenetic classification of prokaryotic and eukaryotic Sir2-like proteins
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3782645
retrieved
6 September 2017
The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3782645
retrieved
6 September 2017
A synaptic model of memory: long-term potentiation in the hippocampus
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3782645
retrieved
6 September 2017
Activation of nuclear factor-kappa B signalling promotes cellular senescence
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3782645
retrieved
14 September 2017
Poly(ADP-ribose) polymerase-1-induced NAD(+) depletion promotes nuclear factor-κB transcriptional activity by preventing p65 de-acetylation.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3782645
retrieved
14 September 2017
The SIRT1 activator resveratrol protects SK-N-BE cells from oxidative stress and against toxicity caused by alpha-synuclein or amyloid-beta (1-42) peptide.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3782645
retrieved
14 September 2017
Mitochondria are a direct site of A beta accumulation in Alzheimer's disease neurons: implications for free radical generation and oxidative damage in disease progression
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3782645
retrieved
14 September 2017
NF-κB inhibition delays DNA damage-induced senescence and aging in mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3782645
retrieved
26 June 2018
Neuroprotective role of Sirt1 in mammalian models of Huntington's disease through activation of multiple Sirt1 targets
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3782645
retrieved
26 June 2018
dSir2 in the adult fat body, but not in muscles, regulates life span in a diet-dependent manner.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3782645
retrieved
3 September 2018
100 years of Lewy pathology.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3782645
retrieved
3 September 2018
SNCA (α-synuclein)-induced toxicity in yeast cells is dependent on sirtuin 2 (Sir2)-mediated mitophagy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3782645
retrieved
3 September 2018
Reversal of aging by NFkappaB blockade
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3782645
retrieved
3 September 2018
Transcriptional repression of PGC-1alpha by mutant huntingtin leads to mitochondrial dysfunction and neurodegeneration.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3782645
retrieved
3 September 2018
SIRT1 protects against microglia-dependent amyloid-beta toxicity through inhibiting NF-kappaB signaling
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3782645
retrieved
3 September 2018
Clinicopathologic studies in cognitively healthy aging and Alzheimer's disease: relation of histologic markers to dementia severity, age, sex, and apolipoprotein E genotype.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3782645
retrieved
3 September 2018
C/EBP is an immediate-early gene required for the consolidation of long-term facilitation in Aplysia
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3782645
retrieved
3 September 2018
Identifiers
DOI
10.3389/FNAGI.2013.00053
1 reference
stated in
Europe PubMed Central
PMC publication ID
3782645
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24093018%20AND%20SRC:MED&resulttype=core&format=json
retrieved
26 February 2020
PMC publication ID
3782645
1 reference
stated in
Europe PubMed Central
PMC publication ID
3782645
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24093018%20AND%20SRC:MED&resulttype=core&format=json
retrieved
26 February 2020
PubMed publication ID
24093018
1 reference
stated in
Europe PubMed Central
PMC publication ID
3782645
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24093018%20AND%20SRC:MED&resulttype=core&format=json
retrieved
26 February 2020
ResearchGate publication ID
257350575
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