(Q37217375)

19 August 2017

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title

Intrinsic and extrinsic control of effector T cell survival and memory T cell development (English)

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19 August 2017

Timothy W Hand

1

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PubMed ID

18629449

19 August 2017

Susan M Kaech

series ordinal

2

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PubMed ID

18629449

19 August 2017

language of work or name

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1 January 2009

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19 August 2017

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19 August 2017

45

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19 August 2017

1

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19 August 2017

46-61

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https://scigraph.springernature.com/pub.10.1007/s12026-008-8027-z

19 August 2017

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cites work

Bim/Bcl-2 balance is critical for maintaining naive and memory T cell homeostasis

1 reference

https://api.crossref.org/works/10.1007%2FS12026-008-8027-Z

IL-15 regulates CD8+ T cell contraction during primary infection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-008-8027-Z

OX40 and Bcl-xL promote the persistence of CD8 T cells to recall tumor-associated antigen.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-008-8027-Z

The contraction phase of virus-specific CD8+ T cells is unaffected by a pan-caspase inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-008-8027-Z

Generation of CD8(+) T cell memory in response to low, high, and excessive levels of epitope

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-008-8027-Z

Memory inflation: continuous accumulation of antiviral CD8+ T cells over time.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-008-8027-Z

Essential role for IL-2 in the regulation of antiviral extralymphoid CD8 T cell responses.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-008-8027-Z

Augmented IL-7 signaling during viral infection drives greater expansion of effector T cells but does not enhance memory

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-008-8027-Z

Cutting Edge: Limiting amounts of IL-7 do not control contraction of CD4+ T cell responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-008-8027-Z

Constitutive expression of IL-7 receptor alpha does not support increased expansion or prevent contraction of antigen-specific CD4 or CD8 T cells following Listeria monocytogenes infection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-008-8027-Z

Cutting edge: IL-7-independent regulation of IL-7 receptor alpha expression and memory CD8 T cell development

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-008-8027-Z

Cutting edge: requirement for IL-15 in the generation of primary and memory antigen-specific CD8 T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-008-8027-Z

IL-15-dependent induction of 4-1BB promotes antigen-independent CD8 memory T cell survival.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-008-8027-Z

Temporal segregation of 4-1BB versus CD28-mediated costimulation: 4-1BB ligand influences T cell numbers late in the primary response and regulates the size of the T cell memory response following influenza infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-008-8027-Z

Innate immune cells contribute to the IFN-gamma-dependent regulation of antigen-specific CD8+ T cell homeostasis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-008-8027-Z

Generation of CD8 T cell memory is regulated by IL-12.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-008-8027-Z

Innate inflammatory signals induced by various pathogens differentially dictate the IFN-I dependence of CD8 T cells for clonal expansion and memory formation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-008-8027-Z

Effector CD8 T cell development: a balancing act between memory cell potential and terminal differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-008-8027-Z

Bcl6 acts as an amplifier for the generation and proliferative capacity of central memory CD8+ T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-008-8027-Z

The forkhead transcription factor FoxO regulates transcription of p27Kip1 and Bim in response to IL-2

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-008-8027-Z

Differential survival of cytotoxic T cells and memory cell precursors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-008-8027-Z

A role for the granzyme B inhibitor serine protease inhibitor 6 in CD8+ memory cell homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-008-8027-Z

Immunological memory and protective immunity: understanding their relation

21 January 2018

1 reference

12 December 2020

Virus-specific CD8+ T-cell memory determined by clonal burst size

1 reference

12 December 2020

Immunological adjuvants promote activated T cell survival via induction of Bcl-3.

1 reference

12 December 2020

Role of tumor necrosis factor receptors in regulating CD8 T-cell responses during acute lymphocytic choriomeningitis virus infection

1 reference

12 December 2020

Development and maintenance of B and T lymphocytes requires antiapoptotic MCL-1.

1 reference

12 December 2020

Long-lived memory CD8+ T cells are programmed by prolonged antigen exposure and low levels of cellular activation.

1 reference

12 December 2020

Suicide induced by cytolytic activity controls the differentiation of memory CD8(+) T lymphocytes

1 reference

12 December 2020

Do CD8 effector cells need IL-7R expression to become resting memory cells?

1 reference

12 December 2020

Liver-Infiltrating Lymphocytes in Chronic Human Hepatitis C Virus Infection Display an Exhausted Phenotype with High Levels of PD-1 and Low Levels of CD127 Expression

1 reference

12 December 2020

Antigen-driven effector CD8 T cell function regulated by T-bet

1 reference

12 December 2020

CD8+ T cell contraction is controlled by early inflammation.

1 reference

12 December 2020

Lack of proliferative capacity of human effector and memory T cells expressing killer cell lectinlike receptor G1 (KLRG1)

1 reference

12 December 2020

Differential roles of interleukin 15 mRNA isoforms generated by alternative splicing in immune responses in vivo

1 reference

12 December 2020

OX40 promotes Bcl-xL and Bcl-2 expression and is essential for long-term survival of CD4 T cells

1 reference

12 December 2020

Interleukin-2 signals during priming are required for secondary expansion of CD8+ memory T cells.

1 reference

12 December 2020

CD4+ T-cell help controls CD8+ T-cell memory via TRAIL-mediated activation-induced cell death.

1 reference

12 December 2020

The Fas/Fas ligand pathway and Bcl-2 regulate T cell responses to model self and foreign antigens

1 reference

12 December 2020

Signal 3 determines tolerance versus full activation of naive CD8 T cells: dissociating proliferation and development of effector function

1 reference

12 December 2020

Cutting Edge: IL-12 inversely regulates T-bet and eomesodermin expression during pathogen-induced CD8+ T cell differentiation

1 reference

12 December 2020

High expression of active CDK6 in the cytoplasm of CD8 memory cells favors rapid division.

1 reference

12 December 2020

Requirement for CD4 T Cell Help in Generating Functional CD8 T Cell Memory

1 reference

12 December 2020

Impaired CD8 T cell memory and CD4 T cell primary responses in IL-7R alpha mutant mice

1 reference

12 December 2020

Caspases and T lymphocytes: a flip of the coin?

1 reference

12 December 2020

Evolution of diverse antiviral CD8+ T cell populations after murine cytomegalovirus infection.

1 reference

12 December 2020

BH3-only proteins that bind pro-survival Bcl-2 family members fail to induce apoptosis in the absence of Bax and Bak

1 reference

12 December 2020

Role for Bcl-6 in the generation and maintenance of memory CD8+ T cells

1 reference

12 December 2020

Aberrant contraction of antigen-specific CD4 T cells after infection in the absence of gamma interferon or its receptor.

1 reference

12 December 2020

Adjuvant IL-7 or IL-15 overcomes immunodominance and improves survival of the CD8+ memory cell pool

1 reference

12 December 2020

Proapoptotic Bcl-2 relative Bim required for certain apoptotic responses, leukocyte homeostasis, and to preclude autoimmunity

1 reference

12 December 2020

Overexpression of interleukin (IL)-7 leads to IL-15-independent generation of memory phenotype CD8+ T cells

1 reference

12 December 2020

Control of T cell viability

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12 December 2020

Signals required for programming effector and memory development by CD8+ T cells

1 reference

12 December 2020

Interleukin-7 mediates the homeostasis of naïve and memory CD8 T cells in vivo

1 reference

12 December 2020

Critical role for perforin-, Fas/FasL-, and TNFR1-mediated cytotoxic pathways in down-regulation of antigen-specific T cells during persistent viral infection

1 reference

12 December 2020

The role of p53 in regulating antiviral T cell responses

1 reference

12 December 2020

Constitutive association of the proapoptotic protein Bim with Bcl-2-related proteins on mitochondria in T cells

1 reference

12 December 2020

Viral immune evasion due to persistence of activated T cells without effector function

1 reference

12 December 2020

Serine protease inhibitor 2A inhibits caspase-independent cell death

1 reference

12 December 2020

Role of T-bet in commitment of TH1 cells before IL-12-dependent selection.

1 reference

12 December 2020

Regulatory mechanisms that determine the development and function of plasma cells

1 reference

12 December 2020

Control of apoptosis in the immune system: Bcl-2, BH3-only proteins and more

1 reference

12 December 2020

NF-kappaB protects from the lysosomal pathway of cell death.

1 reference

12 December 2020

TNF receptor 1 (TNFR1) and CD95 are not required for T cell deletion after virus infection but contribute to peptide-induced deletion under limited conditions

1 reference

12 December 2020

Constitutive expression of Bcl-xL or Bcl-2 prevents peptide antigen-induced T cell deletion but does not influence T cell homeostasis after a viral infection.

1 reference

12 December 2020

Therapeutic use of IL-2 to enhance antiviral T-cell responses in vivo

1 reference

12 December 2020

Expression of IL-7 receptor alpha is necessary but not sufficient for the formation of memory CD8 T cells during viral infection

1 reference

12 December 2020

Transcriptional regulator Id2 mediates CD8+ T cell immunity.

1 reference

12 December 2020

Adoptive immunotherapy for cancer: building on success

1 reference

12 December 2020

Homeostatic control of lymphocyte survival: potential origins and implications

1 reference

12 December 2020

Effector and memory CD8+ T cell fate coupled by T-bet and eomesodermin

1 reference

12 December 2020

Negative regulation of T cell proliferation and interleukin 2 production by the serine threonine kinase GSK-3

1 reference

12 December 2020

Heterogeneity and cell-fate decisions in effector and memory CD8+ T cell differentiation during viral infection

1 reference

12 December 2020

Blimp-1, a novel zinc finger-containing protein that can drive the maturation of B lymphocytes into immunoglobulin-secreting cells

1 reference

12 December 2020

Diverse functions of IL-2, IL-15, and IL-7 in lymphoid homeostasis

1 reference

12 December 2020

Selective expression of IL-7 receptor on memory T cells identifies early CD40L-dependent generation of distinct CD8+ memory T cell subsets

1 reference

12 December 2020

Cytokine requirements for acute and Basal homeostatic proliferation of naive and memory CD8+ T cells

1 reference

12 December 2020

PD-1 Expression in Acute Hepatitis C Virus (HCV) Infection Is Associated with HCV-Specific CD8 Exhaustion

1 reference

12 December 2020

Uncoupling IL-2 signals that regulate T cell proliferation, survival, and Fas-mediated activation-induced cell death

1 reference

12 December 2020

Defective CD8 T Cell Memory Following Acute Infection Without CD4 T Cell Help

1 reference

12 December 2020

Restoring function in exhausted CD8 T cells during chronic viral infection

1 reference

12 December 2020

Discovery and biology of IL-23 and IL-27: related but functionally distinct regulators of inflammation

1 reference

12 December 2020

Antigen-independent memory CD8 T cells do not develop during chronic viral infection

1 reference

12 December 2020

Lymphocyte apoptosis during the silencing of the immune response to acute viral infections in normal, lpr, and Bcl-2-transgenic mice.

1 reference

12 December 2020

Requirement for T-bet in the aberrant differentiation of unhelped memory CD8+ T cells.

1 reference

12 December 2020

Caspases at the crossroads of immune-cell life and death

1 reference

12 December 2020

Interleukin 15 is required for proliferative renewal of virus-specific memory CD8 T cells

1 reference

12 December 2020

Convergence of TCR and cytokine signaling leads to FOXO3a phosphorylation and drives the survival of CD4+ central memory T cells

1 reference

12 December 2020

The fas antigen is involved in peripheral but not thymic deletion of T lymphocytes in T cell receptor transgenic mice

1 reference

12 December 2020

IL-7 receptor expression levels do not identify CD8+ memory T lymphocyte precursors following peptide immunization

1 reference

12 December 2020

Reversible defects in natural killer and memory CD8 T cell lineages in interleukin 15-deficient mice

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12 December 2020

Apoptosis regulators Fas and Bim cooperate in shutdown of chronic immune responses and prevention of autoimmunity

1 reference

12 December 2020

Interleukin 15 controls both proliferation and survival of a subset of memory-phenotype CD8(+) T cells

1 reference

12 December 2020

TRAIL deficiency delays, but does not prevent, erosion in the quality of "helpless" memory CD8 T cells

1 reference

12 December 2020

Cell biology of IL-7, a key lymphotrophin

1 reference

12 December 2020

CD134 Costimulation Couples the CD137 Pathway to Induce Production of Supereffector CD8 T Cells That Become IL-7 Dependent

1 reference

12 December 2020

PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression

1 reference

12 December 2020

Viral antigen and extensive division maintain virus-specific CD8 T cells during chronic infection

1 reference

12 December 2020

Coordinate regulation of complex T cell populations responding to bacterial infection.

1 reference

12 December 2020

Unrestrained glycogen synthase kinase-3 beta activity leads to activated T cell death and can be inhibited by natural adjuvant

1 reference

12 December 2020

Apoptosis initiated when BH3 ligands engage multiple Bcl-2 homologs, not Bax or Bak

1 reference

12 December 2020

Antioxidant treatment reduces expansion and contraction of antigen-specific CD8+ T cells during primary but not secondary viral infection

1 reference

12 December 2020

Accelerated CD8+ T-cell memory and prime-boost response after dendritic-cell vaccination.

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12 December 2020

Direct interferon-gamma signaling dramatically enhances CD4+ and CD8+ T cell memory

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12 December 2020

Loss of T cell receptor-induced Bmi-1 in the KLRG1(+) senescent CD8(+) T lymphocyte

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12 December 2020

Non-redundant role for IL-7R signaling for the survival of CD8+ memory T cells.

1 reference

12 December 2020

Type I interferons act directly on CD8 T cells to allow clonal expansion and memory formation in response to viral infection

1 reference

12 December 2020

The role of BH3-only proteins in the immune system

1 reference

12 December 2020

T-bet controls autoaggressive CD8 lymphocyte responses in type 1 diabetes

1 reference

12 December 2020

Inflammation directs memory precursor and short-lived effector CD8(+) T cell fates via the graded expression of T-bet transcription factor

1 reference

12 December 2020

The structure of a Bcl-xL/Bim fragment complex: implications for Bim function

1 reference

12 December 2020

A novel transcription factor, T-bet, directs Th1 lineage commitment

1 reference

12 December 2020

The NF-kappaB regulator Bcl-3 and the BH3-only proteins Bim and Puma control the death of activated T cells

1 reference

12 December 2020

Transcriptional repressor Blimp-1 regulates T cell homeostasis and function

1 reference

12 December 2020

Programmed contraction of CD8(+) T cells after infection.

1 reference

12 December 2020

Deficiency in Bak and Bax perturbs thymic selection and lymphoid homeostasis.

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12 December 2020

Homeostasis of memory T cells

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12 December 2020

Inflaming the CD8+ T cell response.

1 reference

12 December 2020

Selective expression of the interleukin 7 receptor identifies effector CD8 T cells that give rise to long-lived memory cells.

1 reference

12 December 2020

Interferon-gamma acts directly on CD8+ T cells to increase their abundance during virus infection

1 reference

12 December 2020

Shutdown of an acute T cell immune response to viral infection is mediated by the proapoptotic Bcl-2 homology 3-only protein Bim

1 reference

12 December 2020

Transcriptional repressor Blimp-1 is essential for T cell homeostasis and self-tolerance

1 reference

12 December 2020

Specific ablation of the apoptotic functions of cytochrome C reveals a differential requirement for cytochrome C and Apaf-1 in apoptosis

1 reference

12 December 2020

Interleukin-2 enhances CD4+ T cell memory by promoting the generation of IL-7R alpha-expressing cells

1 reference

12 December 2020

Overexpression of IL-15 in vivo increases antigen-driven memory CD8+ T cells following a microbe exposure

1 reference

12 December 2020

A critical role for TNF receptor-associated factor 1 and Bim down-regulation in CD8 memory T cell survival

1 reference

12 December 2020

Interleukin 7 regulates the survival and generation of memory CD4 cells

1 reference

12 December 2020

Serine protease inhibitor 2A is a protective factor for memory T cell development

1 reference

12 December 2020

Counting antigen-specific CD8 T cells: a reevaluation of bystander activation during viral infection.

1 reference

12 December 2020

Dual roles of IL-15 in maintaining IL-7RalphalowCCR7- memory CD8+ T cells in humans via recovering the phosphatidylinositol 3-kinase/AKT pathway

1 reference

12 December 2020

Activated T cell death in vivo mediated by proapoptotic bcl-2 family member bim.

1 reference

12 December 2020

Serine protease inhibitor 6 protects cytotoxic T cells from self-inflicted injury by ensuring the integrity of cytotoxic granules

1 reference

12 December 2020

Antiviral CD4+ memory T cells are IL-15 dependent

1 reference

12 December 2020

Cutting edge: Bcl-3 up-regulation by signal 3 cytokine (IL-12) prolongs survival of antigen-activated CD8 T cells

1 reference

12 December 2020

The IL-27R (WSX-1) is required to suppress T cell hyperactivity during infection

1 reference

12 December 2020

The antiviral CD8+ T cell response is differentially dependent on CD4+ T cell help over the course of persistent infection

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12 December 2020

CD4+ T cells are required for the maintenance, not programming, of memory CD8+ T cells after acute infection.

1 reference

12 December 2020

TNF family ligands define niches for T cell memory.

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12 December 2020

Caspases 3 and 7: key mediators of mitochondrial events of apoptosis

1 reference

12 December 2020

Apoptosis regulators Bim and Fas function concurrently to control autoimmunity and CD8+ T cell contraction

1 reference

12 December 2020

IL-15 receptor maintains lymphoid homeostasis by supporting lymphocyte homing and proliferation

1 reference

12 December 2020

BCL6b mediates the enhanced magnitude of the secondary response of memory CD8+ T lymphocytes

1 reference

12 December 2020

Apoptosis initiated by Bcl-2-regulated caspase activation independently of the cytochrome c/Apaf-1/caspase-9 apoptosome

1 reference

12 December 2020

Regulation of antigen-specific CD8+ T cell homeostasis by perforin and interferon-gamma.

1 reference

12 December 2020

Reactive Oxygen Species Regulate Activation-Induced T Cell Apoptosis

1 reference

12 December 2020

Massive expansion of antigen-specific CD8+ T cells during an acute virus infection

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12 December 2020

BH3-only protein Puma contributes to death of antigen-specific T cells during shutdown of an immune response to acute viral infection

1 reference

12 December 2020

Effects of IL-7 on memory CD8 T cell homeostasis are influenced by the timing of therapy in mice

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12 December 2020

Bmi1 regulates memory CD4 T cell survival via repression of the Noxa gene

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12 December 2020

Potent and selective stimulation of memory-phenotype CD8+ T cells in vivo by IL-15.

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12 December 2020

Asymmetric T lymphocyte division in the initiation of adaptive immune responses.

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12 December 2020

Bim mediates apoptosis of CD127(lo) effector T cells and limits T cell memory

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12 December 2020

FOXO3a-dependent regulation of Puma in response to cytokine/growth factor withdrawal

1 reference

12 December 2020

10.1007/S12026-008-8027-Z

Identifiers

DOI

1 reference

19 August 2017

1 reference

PubMed ID

18629449