(Q37218436)

19 August 2017

Template-constrained macrocyclic peptides prepared from native, unprotected precursors (English)

1 reference

19 August 2017

Kenneth V Lawson

1

1 reference

19 August 2017

Tristan E Rose

series ordinal

2

1 reference

19 August 2017

Patrick G Harran

series ordinal

3

1 reference

19 August 2017

language of work or name

English

0 references

publication date

16 September 2013

1 reference

Proceedings of the National Academy of Sciences of the United States of America

19 August 2017

1 reference

19 August 2017

110

1 reference

19 August 2017

40

1 reference

19 August 2017

E3753-60

1 reference

Template-induced macrocycle diversity through large ring-forming alkylations of tryptophan

19 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3791740

Incorporation of Non-natural Amino Acids Improves Cell Permeability and Potency of Specific Inhibitors of Proteasome Trypsin-like Sites

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3791740

Global analysis of peptide cyclization efficiency

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3791740

Peptides and peptide conjugates: therapeutics on the upward path

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3791740

Bacteriophages and viruses as a support for organic synthesis and combinatorial chemistry.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3791740

Attributes of short linear motifs.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3791740

Contemporary strategies for peptide macrocyclization

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3791740

Modular assembly of macrocyclic organo-peptide hybrids using synthetic and genetically encoded precursors.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3791740

Macrocycles are great cycles: applications, opportunities, and challenges of synthetic macrocycles in drug discovery

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3791740

Chemical modifications designed to improve peptide stability: incorporation of non-natural amino acids, pseudo-peptide bonds, and cyclization

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3791740

Hydrocarbon double-stapling remedies the proteolytic instability of a lengthy peptide therapeutic

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3791740

Inhibition of protein-protein interactions using designed molecules

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3791740

Diverse backbone-cyclized peptides via codon reprogramming

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3791740

Synthetic therapeutic peptides: science and market

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3791740

Phage-encoded combinatorial chemical libraries based on bicyclic peptides

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3791740

Peptide cyclization and cyclodimerization by Cu(I)-mediated azide-alkyne cycloaddition

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3791740

Acid promoted cinnamyl ion mobility within peptide derived macrocycles

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3791740

Small-molecule inhibitors of protein-protein interactions

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3791740

The exploration of macrocycles for drug discovery--an underexploited structural class

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3791740

Reaching for high-hanging fruit in drug discovery at protein-protein interfaces

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3791740

SLiMFinder: a probabilistic method for identifying over-represented, convergently evolved, short linear motifs in proteins.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3791740

Hot spots--a review of the protein-protein interface determinant amino-acid residues

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3791740

Peptides mediating interaction networks: new leads at last

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3791740

Emerging peptide therapeutics for inflammatory diseases

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3791740

Drugs targeting protein-protein interactions

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3791740

Head-to-tail peptide cyclodimerization by copper-catalyzed azide-alkyne cycloaddition

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3791740

DNA-templated organic synthesis and selection of a library of macrocycles

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3791740

Dynamic interactions between 14-3-3 proteins and phosphoproteins regulate diverse cellular processes.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3791740

Small-molecule inhibitors of protein-protein interactions: progressing towards the dream

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3791740

Structure-based design of an indolicidin peptide analogue with increased protease stability

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3791740

The cyclization of peptides and depsipeptides

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3791740

Recent developments in peptide-based cancer therapeutics.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3791740

Antagonists of protein-protein interactions.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3791740

Convergent solutions to binding at a protein-protein interface

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3791740

Peptide modulators of protein-protein interactions in intracellular signaling

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3791740

Anatomy of hot spots in protein interfaces

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3791740

Serine phosphorylation of death agonist BAD in response to survival factor results in binding to 14-3-3 not BCL-X(L)

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3791740

Screening of cyclic peptide phage libraries identifies ligands that bind streptavidin with high affinities

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3791740

Regulation of tyrosine biosynthesis in Escherichia coli K-12: isolation and characterization of operator mutants

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3791740

Relationship between nuclear magnetic resonance chemical shift and protein secondary structure

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3791740

Multimeric threading-based prediction of protein-protein interactions on a genomic scale: application to the Saccharomyces cerevisiae proteome

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3791740

Synthesis of peptide macrocycles using unprotected amino aldehydes

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3791740

The SLiMDisc server: short, linear motif discovery in proteins

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3791740

Macrocyclizations for medicinal chemistry: synthesis of druglike macrocycles by high-concentration Ullmann coupling.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3791740

Stapling of a 3(10)-helix with click chemistry

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3791740

Counterintuitive kinetics in Tsuji-Trost allylation: ion-pair partitioning and implications for asymmetric catalysis

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3791740

Asymmetric allylic alkylation, an enabling methodology

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3791740

A new tri-orthogonal strategy for peptide cyclization.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3791740

Peptides identify the critical hotspots involved in the biological activation of the insulin receptor

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3791740

Template-constrained somatostatin analogues: a biphenyl linker induces a type-V' turn

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3791740

Amide bond formation and peptide coupling

3 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.1311706110

Cyclic Peptides from Linear Unprotected Peptide Precursors through Thiazolidine Formation†

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.1311706110

A novel, convenient, three-dimensional orthogonal strategy for solid-phase synthesis of cyclic peptides

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.1311706110

Flexible Synthesis of Metacycloprodigiosin and Functional Derivatives Thereof

21 January 2018

1 reference

12 December 2020

Amide proton temperature coefficients as hydrogen bond indicators in proteins

1 reference

12 December 2020

An improved method for the solution cyclization of peptides under pseudo-high dilution conditions

1 reference

12 December 2020

Efficient parallel synthesis of macrocyclic peptidomimetics

1 reference

12 December 2020

Macrocyclization of linear peptides enabled by amphoteric molecules

1 reference

12 December 2020

CuAAC macrocyclization: high intramolecular selectivity through the use of copper-tris(triazole) ligand complexes

1 reference

12 December 2020

Synthesis of all-hydrocarbon stapled α-helical peptides by ring-closing olefin metathesis

1 reference

12 December 2020

New β-strand templates constrained by Huisgen cycloaddition

1 reference

12 December 2020

A new and useful method for the macrocyclization of linear peptides

1 reference

12 December 2020

Highly Efficient Synthesis of Covalently Cross-Linked Peptide Helices by Ring-Closing Metathesis

1 reference

12 December 2020

Cyclotetrapeptides and cyclopentapeptides: occurrence and synthesis

1 reference

12 December 2020

Temperature dependence of 1H chemical shifts in proteins

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.1311706110

1 reference

19 August 2017

0 references

1 reference

19 August 2017

PubMed publication ID

24043790

1 reference