(Q37225885)

19 August 2017

Inactivation of CDK2 is synthetically lethal to MYCN over-expressing cancer cells (English)

1 reference

19 August 2017

Dirk Geerts

3

0 references

Rogier Versteeg

object named as

Rogier Versteeg

8

0 references

Jan Koster

object named as

Jan Koster

4

0 references

Huib N. Caron

9

object named as

Huib N Caron

1 reference

19 August 2017

Jan J Molenaar

1

1 reference

19 August 2017

Marli E Ebus

2

1 reference

19 August 2017

Fieke Lamers

5

1 reference

19 August 2017

Linda J Valentijn

6

1 reference

19 August 2017

Ellen M Westerhout

7

1 reference

19 August 2017

language of work or name

English

0 references

publication date

12 June 2009

1 reference

19 August 2017

6

1 reference

Proceedings of the National Academy of Sciences of the United States of America

inferred from page(s)

published in

1 reference

19 August 2017

106

1 reference

19 August 2017

31

1 reference

19 August 2017

12968-12973

1 reference

Transcription-independent functions of MYC: regulation of translation and DNA replication

19 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2695754

Myeloid ecotropic viral integration site 1 (MEIS) 1 involvement in embryonic implantation

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2695754

The direct p53 target gene, FLJ11259/DRAM, is a member of a novel family of transmembrane proteins

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2695754

Small interfering RNA screens reveal enhanced cisplatin cytotoxicity in tumor cells having both BRCA network and TP53 disruptions

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2695754

The Oscar-worthy role of Myc in apoptosis

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2695754

Cyclin-dependent kinase pathways as targets for cancer treatment

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2695754

The concept of synthetic lethality in the context of anticancer therapy

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2695754

A small molecule-kinase interaction map for clinical kinase inhibitors

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2695754

Living with or without cyclins and cyclin-dependent kinases

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2695754

Regeneration of peroxiredoxins by p53-regulated sestrins, homologs of bacterial AhpD

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2695754

Pediatric neuroblastomas: genetic and epigenetic 'danse macabre'.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2695754

The p53 pathway and its inactivation in neuroblastoma.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2695754

The ferredoxin reductase gene is regulated by the p53 family and sensitizes cells to oxidative stress-induced apoptosis

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2695754

To cycle or not to cycle: a critical decision in cancer.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2695754

N-myc enhances the expression of a large set of genes functioning in ribosome biogenesis and protein synthesis

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2695754

KILLER/DR5 is a DNA damage-inducible p53-regulated death receptor gene

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2695754

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2695754

Distinct roles for cyclin-dependent kinases in cell cycle control

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2695754

Identification of two distinct chromosome 12-derived amplification units in neuroblastoma cell line NGP.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2695754

p53 is nuclear and functional in both undifferentiated and differentiated neuroblastoma

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2695754

Direct regulation of the minichromosome maintenance complex by MYCN in neuroblastoma

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2695754

Inhibition of CDK1 as a potential therapy for tumors over-expressing MYC.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2695754

CYFIP2, a direct p53 target, is leptomycin-B sensitive

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2695754

Specific inhibition of gene expression using a stably integrated, inducible small-interfering-RNA vector

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2695754

Disruption of the cyclin D/cyclin-dependent kinase/INK4/retinoblastoma protein regulatory pathway in human neuroblastoma.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2695754

Cdk1 is sufficient to drive the mammalian cell cycle

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2695754

Cyclin D1 and CDK4 activity contribute to the undifferentiated phenotype in neuroblastoma

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2695754

Analysis of genomic targets reveals complex functions of MYC.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2695754

Proliferation of cancer cells despite CDK2 inhibition.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2695754

Biochemical and cellular effects of roscovitine, a potent and selective inhibitor of the cyclin-dependent kinases cdc2, cdk2 and cdk5.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2695754

3 September 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0901418106

Induction of an interferon response by RNAi vectors in mammalian cells

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.0901418106

Rearrangements and increased expression of cyclin D1 (CCND1) in neuroblastoma

21 January 2018

1 reference

12 December 2020

Lack of class I HLA expression in neuroblastoma is associated with high N-myc expression and hypomethylation due to loss of the MEMO-1 locus

1 reference

12 December 2020

Cyclin E-induced S phase without activation of the pRb/E2F pathway.

1 reference

12 December 2020

Emerging uses for genomic information in drug discovery

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.0901418106

1 reference

19 August 2017

0 references

1 reference

19 August 2017

PubMed publication ID

19525400

1 reference