(Q37228492)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19384296%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

title

Predictors of survival and toxicity in patients on adjuvant therapy with 5-fluorouracil for colorectal cancer (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19384296%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

0 references

1 reference

0 references

1 reference

1 reference

1

1 reference

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26 January 2020

author name string

A C Frigo

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19384296%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

C Bolzonella

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19384296%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

R Marinelli

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19384296%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

C Barile

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19384296%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

A Bononi

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19384296%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

G Crepaldi

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19384296%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

D Menon

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19384296%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

L Stievano

9

1 reference

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26 January 2020

S Toso

10

1 reference

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26 January 2020

F Pasini

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19384296%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

E Ferrazzi

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19384296%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

R Padrini

13

1 reference

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26 January 2020

language of work or name

English

0 references

publication date

21 April 2009

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19384296%20AND%20SRC:MED&resulttype=core&format=json

British Journal of Cancer

26 January 2020

published in

1 reference

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26 January 2020

volume

100

1 reference

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26 January 2020

issue

10

1 reference

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26 January 2020

page(s)

1549-1557

1 reference

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https://scigraph.springernature.com/pub.10.1038/sj.bjc.6605052

26 January 2020

exact match

0 references

cites work

Prognostic value of 5-fluorouracil metabolic enzyme genes in Dukes' stage B and C colorectal cancer patients treated with oral 5-fluorouracil-based adjuvant chemotherapy

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Prognostic significance of thymidylate synthase, dihydropyrimidine dehydrogenase and thymidine phosphorylase protein expression in colorectal cancer patients treated with or without 5-fluorouracil-based chemotherapy

6 September 2017

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6 September 2017

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G>C SNP of thymidylate synthase with respect to colorectal cancer

6 September 2017

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6 September 2017

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The prognostic significance of thymidylate synthase and dihydropyrimidine dehydrogenase in colorectal cancer of 303 patients adjuvantly treated with 5-fluorouracil

6 September 2017

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Pharmacogenetics of folate-related drug targets in cancer treatment

6 September 2017

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Thymidine phosphorylase, dihydropyrimidine dehydrogenase and thymidylate synthase mRNA expression in primary colorectal tumors-correlation to tumor histopathology and clinical follow-up

6 September 2017

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Dihydropyrimidine dehydrogenase and the efficacy and toxicity of 5-fluorouracil

6 September 2017

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Pooled analysis of fluorouracil-based adjuvant therapy for stage II and III colon cancer: who benefits and by how much?

6 September 2017

1 reference

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Thymidylate synthase expression and prognosis in colorectal cancer: a systematic review and meta-analysis

6 September 2017

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PyPop: a software framework for population genomics: analyzing large-scale multi-locus genotype data

6 September 2017

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Pharmacogenetics and folate metabolism -- a promising direction

6 September 2017

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Can pharmacokinetic monitoring improve clinical use of fluorouracil?

6 September 2017

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Fluorouracil: biochemistry and pharmacology

6 September 2017

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Autoregulation of human thymidylate synthase messenger RNA translation by thymidylate synthase

6 September 2017

1 reference

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The influence of fluorouracil outcome parameters on tolerance and efficacy in patients with advanced colorectal cancer

6 September 2017

1 reference

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Prognostic and predictive value of the thymidylate synthase expression in patients with non-metastatic colorectal cancer

14 September 2017

1 reference

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A 6 bp polymorphism in the thymidylate synthase gene causes message instability and is associated with decreased intratumoral TS mRNA levels

14 September 2017

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Folate/vitamin B12 inter-relationships

14 September 2017

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Fluorouracil in colorectal cancer--a tale of two drugs: implications for biochemical modulation

14 September 2017

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Controlled trial of fluorouracil and low-dose leucovorin given for 6 months as postoperative adjuvant therapy for colon cancer

28 September 2017

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Combination of polymorphisms within 5' and 3' untranslated regions of thymidylate synthase gene modulates survival in 5 fluorouracil-treated colorectal cancer patients

26 June 2018

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Thymidylate synthase genotyping is more predictive for therapy response than immunohistochemistry in patients with colon cancer

3 September 2018

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5-fluorouracil pharmacokinetics predicts disease-free survival in patients administered adjuvant chemotherapy for colorectal cancer.

3 September 2018

1 reference

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Role of genetic and nongenetic factors for fluorouracil treatment-related severe toxicity: a prospective clinical trial by the German 5-FU Toxicity Study Group

3 September 2018

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Thymidylate synthase and methylenetetrahydrofolate reductase gene polymorphisms and toxicity to capecitabine in advanced colorectal cancer patients.

3 September 2018

1 reference

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Association of methylenetetrahydrofolate reductase gene polymorphisms and sex-specific survival in patients with metastatic colon cancer

3 September 2018

1 reference

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Influence of thymidylate synthase gene polymorphisms on the survival of colorectal cancer patients receiving adjuvant 5-fluorouracil.

3 September 2018

1 reference

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Pharmacokinetics of bolus 5-fluorouracil: relationship between dose, plasma concentrations, area-under-the-curve and toxicity

3 September 2018

1 reference

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Effects on DNA and RNA after the administration of two different schedules of 5-fluorouracil in colorectal cancer patients

3 September 2018

1 reference

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Thymidylate synthase and methylenetetrahydrofolate reductase gene polymorphism in normal tissue as predictors of fluorouracil sensitivity

3 September 2018

1 reference

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Methylenetetrahydrofolate reductase gene polymorphisms and response to fluorouracil-based treatment in advanced colorectal cancer patients.

3 September 2018

1 reference

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Immunohistochemical evaluation of thymidylate synthase (TS) and p16INK4a in advanced colorectal cancer: implication of TS expression in 5-FU-based adjuvant chemotherapy

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2696766

Thymidylate synthase gene polymorphism predicts toxicity in colorectal cancer patients receiving 5-fluorouracil-based chemotherapy

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2696766

Identification and functional analysis of single nucleotide polymorphism in the tandem repeat sequence of thymidylate synthase gene

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2696766

Intratumoral induction of thymidylate synthase mRNA by 5-FU in colorectal cancer patients: association with survival.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2696766

Individual 5-FU dose adaptation in metastatic colorectal cancer: results of a phase II study using a bimonthly pharmacokinetically intensified LV5FU2 regimen

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2696766

Methylenetetrahydrofolate reductase polymorphism in advanced colorectal cancer: a novel genomic predictor of clinical response to fluoropyrimidine-based chemotherapy

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2696766

Different pathways of 5-fluorouracil metabolism after continuous venous or bolus injection in patients with colon carcinoma: possible predictive value of thymidylate synthetase mRNA and ribonucleotide reductase for 5-fluorouracil sensitivity

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2696766

Relationship between pharmacokinetics of 5-FU in plasma and in saliva, and toxicity of 5-fluorouracil/folinic acid

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2696766

Differential effects of two fluorouracil administration regimens for colorectal cancer.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2696766

Susceptibility to gastric cardia adenocarcinoma and genetic polymorphisms in methylenetetrahydrofolate reductase in an at-risk Chinese population.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2696766

Relationship between plasma concentrations of 5-fluorouracil and 5-fluoro-5,6-dihydrouracil and toxicity of 5-fluorouracil infusions in cancer patients.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2696766

New limited sampling strategy for determining 5-fluorouracil area under the concentration-time curve after rapid intravenous bolus.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2696766

Thymidylate synthase gene polymorphism determines response and toxicity of 5-FU chemotherapy

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2696766

Different lengths of a polymorphic repeat sequence in the thymidylate synthase gene affect translational efficiency but not its gene expression

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2696766

Variations in 5-fluorouracil concentrations of colorectal tissues as compared with dihydropyrimidine dehydrogenase (DPD) enzyme activities and DPD messenger RNA levels

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2696766

Changes in intratumoral thymidylate synthase (TS) and dihydropyrimidine dehydrogenase (DPD) mRNA expression in colorectal and gastric cancer during continuous tegafur infusion

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2696766

Lethal outcome of a patient with a complete dihydropyrimidine dehydrogenase (DPD) deficiency after administration of 5-fluorouracil: frequency of the common IVS14+1G>A mutation causing DPD deficiency.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2696766

Searching expressed sequence tag databases: discovery and confirmation of a common polymorphism in the thymidylate synthase gene.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2696766

A prospective, blinded analysis of thymidylate synthase and p53 expression as prognostic markers in the adjuvant treatment of colorectal cancer

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2696766

Tumor Thymidylate Synthase 1494del6 Genotype As a Prognostic Factor in Colorectal Cancer Patients Receiving Fluorouracil-Based Adjuvant Treatment

4 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2696766

Relationship between fluorouracil systemic exposure and tumor response and patient survival

4 December 2018

1 reference

12 December 2020

Relationship between 5-fluorouracil (5-FU) dose intensity and therapeutic response in patients with advanced colorectal cancer receiving infusional therapy containing 5-FU

1 reference

12 December 2020

Thymidylate synthase, dihydropyrimidine dehydrogenase and thymidine phosphorylase expression in colorectal cancer and normal mucosa in patients

1 reference

12 December 2020

A haplotype of the methylenetetrahydrofolate reductase gene predicts poor tumor response in rectal cancer patients receiving preoperative chemoradiation

1 reference

12 December 2020

Pharmacokinetic and demographic markers of 5-fluorouracil toxicity in 181 patients on adjuvant therapy for colorectal cancer

1 reference

12 December 2020

A novel G/C single-nucleotide polymorphism in the double 28-bp repeat thymidylate synthase allele

1 reference

12 December 2020

Predictive role of thymidylate synthase, dihydropyrimidine dehydrogenase and thymidine phosphorylase expression in colorectal cancer patients receiving adjuvant 5-fluorouracil

1 reference

12 December 2020

Pharmacogenetic profiling in patients with advanced colorectal cancer treated with first-line FOLFOX-4 chemotherapy

1 reference

12 December 2020

A novel single nucleotide polymorphism within the 5' tandem repeat polymorphism of the thymidylate synthase gene abolishes USF-1 binding and alters transcriptional activity

1 reference

12 December 2020

Identifiers

DOI

10.1038/SJ.BJC.6605052

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19384296%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19384296%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

PubMed publication ID

19384296

1 reference