(Q37270535)

19 August 2017

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title

Regulation of T cell integrin function by adapter proteins (English)

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19 August 2017

Rebecca G Baker

1

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19 August 2017

Gary A Koretzky

series ordinal

2

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19 August 2017

publication date

1 January 2008

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19 August 2017

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19 August 2017

volume

42

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19 August 2017

issue

1-3

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19 August 2017

page(s)

132-144

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https://scigraph.springernature.com/pub.10.1007/s12026-008-8047-8

19 August 2017

exact match

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cites work

Control of TCR-mediated activation of beta 1 integrins by the ZAP-70 tyrosine kinase interdomain B region and the linker for activation of T cells adapter protein

1 reference

https://api.crossref.org/works/10.1007%2FS12026-008-8047-8

Functional hierarchy of the N-terminal tyrosines of SLP-76.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-008-8047-8

Tec kinases regulate TCR-mediated recruitment of signaling molecules and integrin-dependent cell adhesion

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-008-8047-8

SLP-76 coordinates Nck-dependent Wiskott-Aldrich syndrome protein recruitment with Vav-1/Cdc42-dependent Wiskott-Aldrich syndrome protein activation at the T cell-APC contact site

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-008-8047-8

Differential roles for Wiskott-Aldrich syndrome protein in immune synapse formation and IL-2 production

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-008-8047-8

Cutting edge: T cell migration regulated by CXCR4 chemokine receptor signaling to ZAP-70 tyrosine kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-008-8047-8

Distinct role of ZAP-70 and Src homology 2 domain-containing leukocyte protein of 76 kDa in the prolonged activation of extracellular signal-regulated protein kinase by the stromal cell-derived factor-1 alpha/CXCL12 chemokine

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12026-008-8047-8

Phospholipase cbeta is critical for T cell chemotaxis.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12026-008-8047-8

Cutting edge: a novel function for the SLAP-130/FYB adapter protein in beta 1 integrin signaling and T lymphocyte migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-008-8047-8

Adhesion-activating phorbol ester increases the mobility of leukocyte integrin LFA-1 in cultured lymphocytes.

21 January 2018

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12 December 2020

ADAP-SLP-76 binding differentially regulates supramolecular activation cluster (SMAC) formation relative to T cell-APC conjugation

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12 December 2020

Proximal, selective, and dynamic interactions between integrin alphaIIbbeta3 and protein tyrosine kinases in living cells

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12 December 2020

Molecular cloning of SLAP-130, an SLP-76-associated substrate of the T cell antigen receptor-stimulated protein tyrosine kinases

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12 December 2020

Four molecular pathways of T cell adhesion to endothelial cells: roles of LFA-1, VCAM-1, and ELAM-1 and changes in pathway hierarchy under different activation conditions

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12 December 2020

Rap1 translates chemokine signals to integrin activation, cell polarization, and motility across vascular endothelium under flow

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12 December 2020

FYN-T-FYB-SLP-76 interactions define a T-cell receptor zeta/CD3-mediated tyrosine phosphorylation pathway that up-regulates interleukin 2 transcription in T-cells

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12 December 2020

Rap1A positively regulates T cells via integrin activation rather than inhibiting lymphocyte signaling

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12 December 2020

Organization of the integrin LFA-1 in nanoclusters regulates its activity

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12 December 2020

The Wiskott-Aldrich syndrome protein acts downstream of CD2 and the CD2AP and PSTPIP1 adaptors to promote formation of the immunological synapse

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12 December 2020

Stromal-cell-derived factor-1/CXCL12-induced chemotaxis of a T cell line involves intracellular signaling through Cbl and Cbl-b and their regulation by Src kinases and CD45.

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12 December 2020

T cell costimulation via the integrin VLA-4 inhibits the actin-dependent centralization of signaling microclusters containing the adaptor SLP-76

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12 December 2020

The Src kinase p56(lck) up-regulates VLA-4 integrin affinity. Implications for rapid spontaneous and chemokine-triggered T cell adhesion to VCAM-1 and fibronectin

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12 December 2020

ZAP-70 tyrosine kinase is required for LFA-1-dependent T cell migration

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12 December 2020

Molecular cloning of SKAP55, a novel protein that associates with the protein tyrosine kinase p59fyn in human T-lymphocytes

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12 December 2020

In vivo disruption of T cell development by expression of a dominant-negative polypeptide designed to abolish the SLP-76/Gads interaction

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12 December 2020

RIAM, an Ena/VASP and Profilin ligand, interacts with Rap1-GTP and mediates Rap1-induced adhesion

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12 December 2020

Essential role for Rap1 GTPase and its guanine exchange factor CalDAG-GEFI in LFA-1 but not VLA-4 integrin mediated human T-cell adhesion

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12 December 2020

The ADAP/SKAP55 signaling module regulates T-cell receptor-mediated integrin activation through plasma membrane targeting of Rap1

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12 December 2020

Crucial functions of the Rap1 effector molecule RAPL in lymphocyte and dendritic cell trafficking

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12 December 2020

Structural basis of integrin activation by talin

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12 December 2020

RAPL, a Rap1-binding molecule that mediates Rap1-induced adhesion through spatial regulation of LFA-1

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12 December 2020

Defective T-cell receptor signalling and positive selection of Vav-deficient CD4+ CD8+ thymocytes

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12 December 2020

Deficiency of ADAP/Fyb/SLAP-130 destabilizes SKAP55 in Jurkat T cells

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12 December 2020

Differential requirement for SLP-76 domains in T cell development and function

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12 December 2020

The molecular adapter SLP-76 relays signals from platelet integrin alphaIIbbeta3 to the actin cytoskeleton.

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12 December 2020

Opposing Effects of PKCθ and WASp on Symmetry Breaking and Relocation of the Immunological Synapse

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12 December 2020

Rap1-induced p38 mitogen-activated protein kinase activation facilitates AMPA receptor trafficking via the GDI.Rab5 complex. Potential role in (S)-3,5-dihydroxyphenylglycene-induced long term depression

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12 December 2020

Calpain cleavage promotes talin binding to the beta 3 integrin cytoplasmic domain

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12 December 2020

Complementation in trans of altered thymocyte development in mice expressing mutant forms of the adaptor molecule SLP76.

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12 December 2020

Global conformational rearrangements in integrin extracellular domains in outside-in and inside-out signaling

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12 December 2020

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12 December 2020

Newly generated T cell receptor microclusters initiate and sustain T cell activation by recruitment of Zap70 and SLP-76.

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12 December 2020

CXCR4 physically associates with the T cell receptor to signal in T cells

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12 December 2020

Protein kinase D1 and the beta 1 integrin cytoplasmic domain control beta 1 integrin function via regulation of Rap1 activation.

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12 December 2020

Intracellular mediators of CXCR4-dependent signaling in T cells

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12 December 2020

Structures of the alpha L I domain and its complex with ICAM-1 reveal a shape-shifting pathway for integrin regulation

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12 December 2020

T-cell receptor cross-linking transiently stimulates adhesiveness through LFA-1

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12 December 2020

Wiskott-Aldrich syndrome protein-deficient mice reveal a role for WASP in T but not B cell activation

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12 December 2020

The N-terminal SH2 domains of Syk and ZAP-70 mediate phosphotyrosine-independent binding to integrin beta cytoplasmic domains.

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12 December 2020

SH3 domain recognition of a proline-independent tyrosine-based RKxxYxxY motif in immune cell adaptor SKAP55

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12 December 2020

Rap1-mediated lymphocyte function-associated antigen-1 activation by the T cell antigen receptor is dependent on phospholipase C-gamma1

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12 December 2020

Coordinate interactions of Csk, Src, and Syk kinases with [alpha]IIb[beta]3 initiate integrin signaling to the cytoskeleton

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12 December 2020

Talin Binding to Integrin ß Tails: A Final Common Step in Integrin Activation

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12 December 2020

The actin cloud induced by LFA-1-mediated outside-in signals lowers the threshold for T-cell activation

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12 December 2020

Positive Regulation of T Cell Activation and Integrin Adhesion by the Adapter Fyb/Slap

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12 December 2020

Spleen tyrosine kinase Syk is necessary for E-selectin-induced alpha(L)beta(2) integrin-mediated rolling on intercellular adhesion molecule-1.

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12 December 2020

Cutting edge: SLP-76 cooperativity with FYB/FYN-T in the Up-regulation of TCR-driven IL-2 transcription requires SLP-76 binding to FYB at Tyr595 and Tyr651

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12 December 2020

Requirement for the leukocyte-specific adapter protein SLP-76 for normal T cell development

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12 December 2020

Coupling of the TCR to integrin activation by Slap-130/Fyb.

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12 December 2020

Differential requirement for LAT and SLP-76 in GPVI versus T cell receptor signaling

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12 December 2020

Integrin signaling in neutrophils and macrophages uses adaptors containing immunoreceptor tyrosine-based activation motifs

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12 December 2020

Activation of Syk protein tyrosine kinase through interaction with integrin beta cytoplasmic domains

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12 December 2020

Rap1 is a potent activation signal for leukocyte function-associated antigen 1 distinct from protein kinase C and phosphatidylinositol-3-OH kinase

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12 December 2020

Vav is a regulator of cytoskeletal reorganization mediated by the T-cell receptor

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12 December 2020

Fyn-binding protein (Fyb)/SLP-76-associated protein (SLAP), Ena/vasodilator-stimulated phosphoprotein (VASP) proteins and the Arp2/3 complex link T cell receptor (TCR) signaling to the actin cytoskeleton

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12 December 2020

ADAP is required for normal alphaIIbbeta3 activation by VWF/GP Ib-IX-V and other agonists.

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12 December 2020

Signaling through ZAP-70 is required for CXCL12-mediated T-cell transendothelial migration

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12 December 2020

Small GTPases and LFA-1 reciprocally modulate adhesion and signaling

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12 December 2020

Formins regulate the actin-related protein 2/3 complex-independent polarization of the centrosome to the immunological synapse

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12 December 2020

Protein kinase D signaling

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12 December 2020

Rap1 up-regulation and activation on plasma membrane regulates T cell adhesion.

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12 December 2020

Molecular interaction between the Fyn-associated protein SKAP55 and the SLP-76-associated phosphoprotein SLAP-130

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12 December 2020

Binding of paxillin to alpha4 integrins modifies integrin-dependent biological responses

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12 December 2020

Reconstructing and deconstructing agonist-induced activation of integrin alphaIIbbeta3.

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12 December 2020

Conditional deletion reveals a cell-autonomous requirement of SLP-76 for thymocyte selection

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12 December 2020

Cytoskeletal regulation couples LFA-1 conformational changes to receptor lateral mobility and clustering

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12 December 2020

Structural basis of integrin regulation and signaling

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12 December 2020

Rap1A-deficient T and B cells show impaired integrin-mediated cell adhesion

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12 December 2020

p52Shc is required for CXCR4-dependent signaling and chemotaxis in T cells

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12 December 2020

Requirements of SLP76 tyrosines in ITAM and integrin receptor signaling and in platelet function in vivo

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12 December 2020

Src kinase activation by direct interaction with the integrin β cytoplasmic domain

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12 December 2020

Roles of the proline-rich domain in SLP-76 subcellular localization and T cell function.

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12 December 2020

Dynamic actin polymerization drives T cell receptor-induced spreading: a role for the signal transduction adaptor LAT.

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12 December 2020

Regulation and function of SKAP-55 non-canonical motif binding to the SH3c domain of adhesion and degranulation-promoting adaptor protein

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12 December 2020

T cell receptor ligation induces the formation of dynamically regulated signaling assemblies

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12 December 2020

SLP-76 regulates Fcgamma receptor and integrin signaling in neutrophils

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12 December 2020

Vav1 controls integrin clustering and MHC/peptide-specific cell adhesion to antigen-presenting cells

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12 December 2020

RIAM links the ADAP/SKAP-55 signaling module to Rap1, facilitating T-cell-receptor-mediated integrin activation

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12 December 2020

Evidence for the requirement of ITAM domains but not SLP-76/Gads interaction for integrin signaling in hematopoietic cells.

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12 December 2020

SLP76 and SLP65: complex regulation of signalling in lymphocytes and beyond

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12 December 2020

Vav1 and Rac control chemokine-promoted T lymphocyte adhesion mediated by the integrin alpha4beta1

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12 December 2020

10.1007/S12026-008-8047-8

Identifiers

DOI

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19 August 2017

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