(Q37272764)

English

KNS-760704 [(6R)-4,5,6,7-tetrahydro-N6-propyl-2, 6-benzothiazole-diamine dihydrochloride monohydrate] for the treatment of amyotrophic lateral sclerosis.

scientific article published on January 2008

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18801114%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

1 reference

Europe PubMed Central

KNS-760704 [(6R)-4,5,6,7-tetrahydro-N6-propyl-2, 6-benzothiazole-diamine dihydrochloride monohydrate] for the treatment of amyotrophic lateral sclerosis (English)

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18801114%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

amyotrophic lateral sclerosis

0 references

author name string

Valentin K Gribkoff

1

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18801114%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

Michael E Bozik

2

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18801114%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

language of work or name

1 reference

based on heuristic

inferred from title

publication date

1 January 2008

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18801114%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

CNS Neuroscience & Therapeutics

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18801114%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

14

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18801114%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

3

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18801114%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

215-226

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18801114%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

Natural history of ALS: symptoms, strength, pulmonary function, and disability

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2008.00048.X

21 January 2018

The epidemiology of ALS and the role of population-based registries

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2008.00048.X

21 January 2018

Structure, folding, and misfolding of Cu,Zn superoxide dismutase in amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2008.00048.X

21 January 2018

Mechanisms of selective motor neuron death in transgenic mouse models of motor neuron disease.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2008.00048.X

21 January 2018

Transgenic mouse models of amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2008.00048.X

21 January 2018

The mitochondrial permeability transition pore

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2008.00048.X

21 January 2018

Mitochondria and cell death.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2008.00048.X

21 January 2018

The pharmacology and mechanism of action of riluzole

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2008.00048.X

21 January 2018

Oxidative stress in amyotrophic lateral sclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/18801114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of excitotoxicity in ALS--what is the evidence?

1 reference

https://pubmed.ncbi.nlm.nih.gov/18801114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Toxicity of ALS-linked SOD1 mutants

1 reference

https://pubmed.ncbi.nlm.nih.gov/18801114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The internal structure of mitochondria

1 reference

https://pubmed.ncbi.nlm.nih.gov/18801114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increase of bcl-2 protein in neuronal dendritic processes of cerebral cortex and hippocampus by the antiparkinsonian drugs, talipexole and pramipexole

1 reference

https://pubmed.ncbi.nlm.nih.gov/18801114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apoptotic and antiapoptotic mechanisms in stroke.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18801114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondrial DNA deletion mutation levels are elevated in ALS brains

1 reference

https://pubmed.ncbi.nlm.nih.gov/18801114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondria: execution central

1 reference

https://pubmed.ncbi.nlm.nih.gov/18801114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antioxidant property of pramipexole independent of dopamine receptor activation in neuroprotection

1 reference

https://pubmed.ncbi.nlm.nih.gov/18801114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Release and aggregation of cytochrome c and alpha-synuclein are inhibited by the antiparkinsonian drugs, talipexole and pramipexole

1 reference

https://pubmed.ncbi.nlm.nih.gov/18801114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Import of proteins into mitochondria: a novel pathomechanism for progressive neurodegeneration

1 reference

https://pubmed.ncbi.nlm.nih.gov/18801114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vitro effects of E3040, a dual inhibitor of 5-lipoxygenase and thromboxane A(2) synthetase, on eicosanoid production

1 reference

https://pubmed.ncbi.nlm.nih.gov/18801114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apoptosis: live or die--hard work either way!

1 reference

https://pubmed.ncbi.nlm.nih.gov/18801114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

From Charcot to Lou Gehrig: deciphering selective motor neuron death in ALS

1 reference

https://pubmed.ncbi.nlm.nih.gov/18801114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Histological evidence of protein aggregation in mutant SOD1 transgenic mice and in amyotrophic lateral sclerosis neural tissues

1 reference

https://pubmed.ncbi.nlm.nih.gov/18801114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition by R(+) or S(-) pramipexole of caspase activation and cell death induced by methylpyridinium ion or beta amyloid peptide in SH-SY5Y neuroblastoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/18801114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The permeability transition pore complex: another view.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18801114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Superoxide dismutase multigene family: a comparison of the CuZn-SOD (SOD1), Mn-SOD (SOD2), and EC-SOD (SOD3) gene structures, evolution, and expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/18801114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of benzothiazoles as potential polyglutamine aggregation inhibitors of Huntington's disease by using an automated filter retardation assay

1 reference

https://pubmed.ncbi.nlm.nih.gov/18801114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Do oxidatively modified proteins cause ALS?

1 reference

https://pubmed.ncbi.nlm.nih.gov/18801114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetic epidemiology of amyotrophic lateral sclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/18801114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The perplexing role of copper-zinc superoxide dismutase in amyotrophic lateral sclerosis (Lou Gehrig's disease)

1 reference

https://pubmed.ncbi.nlm.nih.gov/18801114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Misfolded CuZnSOD and amyotrophic lateral sclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/18801114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Large-conductance Ca2+- activated K+ channels:physiological role and pharmacology

1 reference

https://pubmed.ncbi.nlm.nih.gov/18801114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuroprotective mechanisms of antiparkinsonian dopamine D2-receptor subfamily agonists

1 reference

https://pubmed.ncbi.nlm.nih.gov/18801114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular and cellular mechanism of glutamate receptors in relation to amyotrophic lateral sclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/18801114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pramipexole inhibits MPTP toxicity in mice by dopamine D3 receptor dependent and independent mechanisms

1 reference

https://pubmed.ncbi.nlm.nih.gov/18801114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amyotrophic lateral sclerosis: a review of current concepts.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18801114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Use of the Potassium Channel Activator Riluzole to Test Whether Potassium Channels Mediate the Capacity of Isoflurane to Produce Immobility

1 reference

https://pubmed.ncbi.nlm.nih.gov/18801114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondrial formation of reactive oxygen species

1 reference

https://pubmed.ncbi.nlm.nih.gov/18801114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein aggregation in motor neurone disorders.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18801114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Programmed cell death in amyotrophic lateral sclerosis: a mechanism of pathogenic and therapeutic importance

1 reference

https://pubmed.ncbi.nlm.nih.gov/18801114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurodegenerative diseases and oxidative stress

1 reference

https://pubmed.ncbi.nlm.nih.gov/18801114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Imaging brain amyloid in Alzheimer's disease with Pittsburgh Compound-B

1 reference

https://pubmed.ncbi.nlm.nih.gov/18801114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Direct inhibition of the mitochondrial permeability transition pore: a possible mechanism responsible for anti-apoptotic effects of melatonin

1 reference

https://pubmed.ncbi.nlm.nih.gov/18801114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanisms underlying the riluzole inhibition of glutamate release from rat cerebral cortex nerve terminals (synaptosomes).

1 reference

https://pubmed.ncbi.nlm.nih.gov/18801114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synthesis and structure-activity relationships of new antimicrobial active multisubstituted benzazole derivatives

1 reference

https://pubmed.ncbi.nlm.nih.gov/18801114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Unraveling the mechanisms involved in motor neuron degeneration in ALS

1 reference

https://pubmed.ncbi.nlm.nih.gov/18801114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondrial superoxide: production, biological effects, and activation of uncoupling proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/18801114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondrial degeneration in amyotrophic lateral sclerosis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18801114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

New developments in mitochondrial assembly

1 reference

https://pubmed.ncbi.nlm.nih.gov/18801114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pramipexole protects against apoptotic cell death by non-dopaminergic mechanisms

1 reference

https://pubmed.ncbi.nlm.nih.gov/18801114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondrial permeability transition in CNS trauma: cause or effect of neuronal cell death?

1 reference

https://pubmed.ncbi.nlm.nih.gov/18801114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondria and neuronal death/survival signaling pathways in cerebral ischemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/18801114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amyotrophic lateral sclerosis mutations have the greatest destabilizing effect on the apo- and reduced form of SOD1, leading to unfolding and oxidative aggregation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18801114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structural consequences of the familial amyotrophic lateral sclerosis SOD1 mutant His46Arg.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18801114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oxidative stress, mitochondrial dysfunction and cellular stress response in Friedreich's ataxia

1 reference

https://pubmed.ncbi.nlm.nih.gov/18801114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The biology and pathology of hypoxia-ischemia: an update.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18801114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adult motor neuron apoptosis is mediated by nitric oxide and Fas death receptor linked by DNA damage and p53 activation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18801114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evaluation of the benzothiazole aggregation inhibitors riluzole and PGL-135 as therapeutics for Huntington's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/18801114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Production of reactive oxygen species in brain mitochondria: contribution by electron transport chain and non-electron transport chain sources

1 reference

https://pubmed.ncbi.nlm.nih.gov/18801114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Muscular mitochondrial function in amyotrophic lateral sclerosis is progressively altered as the disease develops: A temporal study in man

1 reference

https://pubmed.ncbi.nlm.nih.gov/18801114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

mtDNA mutations and common neurodegenerative disorders

1 reference

https://pubmed.ncbi.nlm.nih.gov/18801114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Targeted antioxidative and neuroprotective properties of the dopamine agonist pramipexole and its nondopaminergic enantiomer SND919CL2x [(+)2-amino-4,5,6,7-tetrahydro-6-Lpropylamino-benzathiazole dihydrochloride].

1 reference

https://pubmed.ncbi.nlm.nih.gov/18801114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The organization and inheritance of the mitochondrial genome

1 reference

https://pubmed.ncbi.nlm.nih.gov/18801114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pramipexole protects against H2O2-induced PC12 cell death

1 reference

https://pubmed.ncbi.nlm.nih.gov/18801114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Patch clamp reveals powerful blockade of the mitochondrial permeability transition pore by the D2-receptor agonist pramipexole

1 reference

https://pubmed.ncbi.nlm.nih.gov/18801114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondrial DNA maintenance and bioenergetics

1 reference

https://pubmed.ncbi.nlm.nih.gov/18801114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Conversion to the amyotrophic lateral sclerosis phenotype is associated with intermolecular linked insoluble aggregates of SOD1 in mitochondria

1 reference

https://pubmed.ncbi.nlm.nih.gov/18801114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The mitochondrial permeability transition from in vitro artifact to disease target

1 reference

https://pubmed.ncbi.nlm.nih.gov/18801114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structure and dynamics of the mitochondrial inner membrane cristae

1 reference

https://pubmed.ncbi.nlm.nih.gov/18801114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Posttranslational modifications in Cu,Zn-superoxide dismutase and mutations associated with amyotrophic lateral sclerosis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18801114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondria: more than just a powerhouse

1 reference

https://pubmed.ncbi.nlm.nih.gov/18801114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondria in amyotrophic lateral sclerosis: a trigger and a target

1 reference

https://pubmed.ncbi.nlm.nih.gov/18801114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ALS: a disease of motor neurons and their nonneuronal neighbors

1 reference

https://pubmed.ncbi.nlm.nih.gov/18801114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oxidative stress, mitochondrial dysfunction, and stress signaling in Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/18801114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

TDP-43 is a component of ubiquitin-positive tau-negative inclusions in frontotemporal lobar degeneration and amyotrophic lateral sclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/18801114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Electrophysiological characterization of the Cyclophilin D-deleted mitochondrial permeability transition pore

1 reference

https://pubmed.ncbi.nlm.nih.gov/18801114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Riluzole for amyotrophic lateral sclerosis (ALS)/motor neuron disease (MND)

1 reference

https://pubmed.ncbi.nlm.nih.gov/18801114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oxidative stress and mitochondrial dysfunction in neurodegenerative diseases

1 reference

https://pubmed.ncbi.nlm.nih.gov/18801114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

TDP-43 immunoreactivity in neuronal inclusions in familial amyotrophic lateral sclerosis with or without SOD1 gene mutation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18801114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondrial dysfunction in Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/18801114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Delayed neuronal death after brain trauma involves p53-dependent inhibition of NF-kappaB transcriptional activity.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18801114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pathological TDP-43 distinguishes sporadic amyotrophic lateral sclerosis from amyotrophic lateral sclerosis with SOD1 mutations.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18801114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pink1, Parkin, DJ-1 and mitochondrial dysfunction in Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/18801114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Benzothiazole bipyridine complexes of ruthenium(II) with cytotoxic activity.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18801114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

TDP-43 in differential diagnosis of motor neuron disorders

1 reference

https://pubmed.ncbi.nlm.nih.gov/18801114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondrial permeability transition pore opening as an endpoint to initiate cell death and as a putative target for cardioprotection

1 reference

https://pubmed.ncbi.nlm.nih.gov/18801114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Therapeutic potential of neuronal two-pore domain potassium-channel modulators

1 reference

https://pubmed.ncbi.nlm.nih.gov/18801114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cognition and amyotrophic lateral sclerosis (ALS).

1 reference

https://pubmed.ncbi.nlm.nih.gov/18801114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inducible alterations of glutathione levels in adult dopaminergic midbrain neurons result in nigrostriatal degeneration.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18801114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

R+ pramipexole as a mitochondrially focused neuroprotectant: initial early phase studies in ALS.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18801114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

TDP-43 mutations in familial and sporadic amyotrophic lateral sclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/18801114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

TARDBP mutations in amyotrophic lateral sclerosis with TDP-43 neuropathology: a genetic and histopathological analysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/18801114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondria: structure and function

1 reference

https://pubmed.ncbi.nlm.nih.gov/18801114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dopamine autoreceptor agonists: resolution and pharmacological activity of 2,6-diaminotetrahydrobenzothiazole and an aminothiazole analogue of apomorphine

1 reference

https://pubmed.ncbi.nlm.nih.gov/18801114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fine structure of anterior horns in patients without amyotrophic lateral sclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/18801114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fine structural study of neurofibrillary changes in a family with amyotrophic lateral sclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/18801114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dopamine receptor agonist potencies for inhibition of cell firing correlate with dopamine D3 receptor binding affinities

1 reference

https://pubmed.ncbi.nlm.nih.gov/18801114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An adverse property of a familial ALS-linked SOD1 mutation causes motor neuron disease characterized by vacuolar degeneration of mitochondria

1 reference

https://pubmed.ncbi.nlm.nih.gov/18801114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pramipexole binding and activation of cloned and expressed dopamine D2, D3 and D4 receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/18801114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Superoxide dismutase 1 subunits with mutations linked to familial amyotrophic lateral sclerosis do not affect wild-type subunit function.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18801114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Recent progress on regulation of the mitochondrial permeability transition pore; a cyclosporin-sensitive pore in the inner mitochondrial membrane

1 reference

https://pubmed.ncbi.nlm.nih.gov/18801114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A frequent ala 4 to val superoxide dismutase-1 mutation is associated with a rapidly progressive familial amyotrophic lateral sclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/18801114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Superoxide dismutase 1 with mutations linked to familial amyotrophic lateral sclerosis possesses significant activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/18801114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Block of the rat brain IIA sodium channel alpha subunit by the neuroprotective drug riluzole.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18801114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Eye movement in amyotrophic lateral sclerosis: a longitudinal study.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18801114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical epidemiology of amyotrophic lateral sclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/18801114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanisms of selective motor neuron death in ALS: insights from transgenic mouse models of motor neuron disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/18801114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuroprotective effects of the dopamine D2/D3 agonist pramipexole against postischemic or methamphetamine-induced degeneration of nigrostriatal neurons.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18801114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuroprotective effects of the dopamine agonists pramipexole and bromocriptine in 3-acetylpyridine-treated rats.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18801114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Riluzole reduces brain lesions and improves neurological function in rats after a traumatic brain injury.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18801114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential action of riluzole on tetrodotoxin-sensitive and tetrodotoxin-resistant sodium channels.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18801114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of the neuroprotective agent riluzole on the high voltage-activated calcium channels of rat dorsal root ganglion neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/18801114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amyotrophic lateral sclerosis. Insights from genetics

1 reference

https://pubmed.ncbi.nlm.nih.gov/18801114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amyotrophic lateral sclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/18801114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pramipexole reduces reactive oxygen species production in vivo and in vitro and inhibits the mitochondrial permeability transition produced by the parkinsonian neurotoxin methylpyridinium ion.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18801114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondrial control of apoptosis: the role of cytochrome c

1 reference

https://pubmed.ncbi.nlm.nih.gov/18801114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Aggregation and Motor Neuron Toxicity of an ALS-Linked SOD1 Mutant Independent from Wild-Type SOD1

1 reference

https://pubmed.ncbi.nlm.nih.gov/18801114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondria in sporadic amyotrophic lateral sclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/18801114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biology and pathology of the mitochondrion

1 reference

https://pubmed.ncbi.nlm.nih.gov/18801114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1111/J.1755-5949.2008.00048.X

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18801114%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18801114%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18801114%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

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