(Q37284069)

19 August 2017

Conservation of protein abundance patterns reveals the regulatory architecture of the EGFR-MAPK pathway (English)

1 reference

19 August 2017

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27405981%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Peter K. Sorger

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27405981%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Wei-Jun Qian

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27405981%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Steven Wiley

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27405981%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

10

Karin D Rodland

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27405981%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

5

Carrie D Nicora

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27405981%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

author name string

Tujin Shi

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27405981%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Mario Niepel

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27405981%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Yuqian Gao

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27405981%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

William B Chrisler

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27405981%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Lye M Markillie

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27405981%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Vladislav A Petyuk

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27405981%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Richard D Smith

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27405981%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

publication date

12 July 2016

1 reference

19 August 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27405981%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

volume

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27405981%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

issue

436

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27405981%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

page(s)

rs6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27405981%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

10 June 2020

Cytoscape

1 reference

9 June 2022

https://europepmc.org/search?query=(METHODS:'Cytoscape')

inferred from PubMed Central ID database lookup

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Mutation-induced protein interaction kinetics changes affect apoptotic network dynamic properties and facilitate oncogenesis

1 reference

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Empirical inference of circuitry and plasticity in a kinase signaling network

6 September 2017

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The proteomic landscape of triple-negative breast cancer

6 September 2017

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Use of mechanistic models to integrate and analyze multiple proteomic datasets

6 September 2017

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Sensitive targeted quantification of ERK phosphorylation dynamics and stoichiometry in human cells without affinity enrichment

6 September 2017

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Isobaric labeling-based relative quantification in shotgun proteomics

6 September 2017

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Fine specificity and molecular competition in SLAM family receptor signalling

6 September 2017

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Quantification of ErbB network proteins in three cell types using complementary approaches identifies cell-general and cell-type-specific signaling proteins

6 September 2017

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Primate transcript and protein expression levels evolve under compensatory selection pressures

6 September 2017

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Changes in translational efficiency is a dominant regulatory mechanism in the environmental response of bacteria.

6 September 2017

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Profiles of Basal and stimulated receptor signaling networks predict drug response in breast cancer lines

6 September 2017

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TCPA: a resource for cancer functional proteomics data

6 September 2017

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Long-gradient separations coupled with selected reaction monitoring for highly sensitive, large scale targeted protein quantification in a single analysis.

6 September 2017

1 reference

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Temporal regulation of EGF signalling networks by the scaffold protein Shc1

6 September 2017

1 reference

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Heterogeneous kinetics of AKT signaling in individual cells are accounted for by variable protein concentration

6 September 2017

1 reference

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Antibody-free, targeted mass-spectrometric approach for quantification of proteins at low picogram per milliliter levels in human plasma/serum

6 September 2017

1 reference

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DUSPs, to MAP kinases and beyond.

6 September 2017

1 reference

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Advancing the sensitivity of selected reaction monitoring-based targeted quantitative proteomics

6 September 2017

1 reference

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Creating and analyzing pathway and protein interaction compendia for modelling signal transduction networks

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5036860

Network analysis of epidermal growth factor signaling using integrated genomic, proteomic and phosphorylation data

6 September 2017

1 reference

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Insights into the regulation of protein abundance from proteomic and transcriptomic analyses

6 September 2017

1 reference

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Comparative proteomic analysis of eleven common cell lines reveals ubiquitous but varying expression of most proteins

6 September 2017

1 reference

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Deep proteome and transcriptome mapping of a human cancer cell line

6 September 2017

1 reference

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Characterization and improvement of RNA-Seq precision in quantitative transcript expression profiling.

6 September 2017

1 reference

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Liquid chromatography-mass spectrometry-based quantitative proteomics.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5036860

Global quantification of mammalian gene expression control

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5036860

Hallmarks of Cancer: The Next Generation

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5036860

High- and low-affinity epidermal growth factor receptor-ligand interactions activate distinct signaling pathways

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5036860

Rational, biologically based treatment of EGFR-mutant non-small-cell lung cancer

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5036860

Multiple mechanisms collectively regulate clathrin-mediated endocytosis of the epidermal growth factor receptor

6 September 2017

1 reference

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Structure of the EGF receptor transactivation circuit integrates multiple signals with cell context

6 September 2017

1 reference

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Signal transduction networks in cancer: quantitative parameters influence network topology

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5036860

Skyline: an open source document editor for creating and analyzing targeted proteomics experiments

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5036860

Molecular and clinical analysis of RAF1 in Noonan syndrome and related disorders: dephosphorylation of serine 259 as the essential mechanism for mutant activation

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5036860

Correlation of mRNA and protein in complex biological samples.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5036860

iTRAQ underestimation in simple and complex mixtures: "the good, the bad and the ugly".

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5036860

Systems-level interactions between insulin-EGF networks amplify mitogenic signaling.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5036860

PI3K-dependent cross-talk interactions converge with Ras as quantifiable inputs integrated by Erk

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5036860

Protein promiscuity and its implications for biotechnology

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5036860

Linear combinations of docking affinities explain quantitative differences in RTK signaling

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5036860

Multiple mechanisms are responsible for transactivation of the epidermal growth factor receptor in mammary epithelial cells.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5036860

Recurrent design patterns in the feedback regulation of the mammalian signalling network

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5036860

DAnTE: a statistical tool for quantitative analysis of -omics data.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5036860

The evolutionarily conserved EBR module of RALT/MIG6 mediates suppression of the EGFR catalytic activity

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5036860

Targeting the Raf-MEK-ERK mitogen-activated protein kinase cascade for the treatment of cancer

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5036860

Multiple reaction monitoring for robust quantitative proteomic analysis of cellular signaling networks

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5036860

The role of Shp2 (PTPN11) in cancer.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5036860

Germline gain-of-function mutations in SOS1 cause Noonan syndrome

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5036860

EGF-ERBB signalling: towards the systems level

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5036860

Improved proteome coverage by using high efficiency cysteinyl peptide enrichment: the human mammary epithelial cell proteome

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5036860

A novel role for Gab1 and SHP2 in epidermal growth factor-induced Ras activation

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5036860

Multiplexed protein quantitation in Saccharomyces cerevisiae using amine-reactive isobaric tagging reagents

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5036860

A model for random sampling and estimation of relative protein abundance in shotgun proteomics

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5036860

Negative regulation of HER2 signaling by the PEST-type protein-tyrosine phosphatase BDP1.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5036860

Cytoscape: a software environment for integrated models of biomolecular interaction networks

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5036860

Large genomic deletions and duplications in the BRCA1 gene identified by a novel quantitative method

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5036860

Computational modeling of the dynamics of the MAP kinase cascade activated by surface and internalized EGF receptors

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5036860

EGFR and cancer prognosis

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5036860

The Sos1 and Sos2 Ras-specific exchange factors: differences in placental expression and signaling properties

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5036860

Metalloprotease-mediated ligand release regulates autocrine signaling through the epidermal growth factor receptor

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5036860

The signaling adapter FRS-2 competes with Shc for binding to the nerve growth factor receptor TrkA. A model for discriminating proliferation and differentiation

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5036860

The statistical-thermodynamic basis for computation of binding affinities: a critical review

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5036860

Epidermal growth factor regulates p21ras through the formation of a complex of receptor, Grb2 adapter protein, and Sos nucleotide exchange factor

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5036860

Differential interactions of human Sos1 and Sos2 with Grb2

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5036860

Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5036860

The human c-Kirsten ras gene is activated by a novel mutation in codon 13 in the breast carcinoma cell line MDA-MB231.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5036860

Overexpression of the EGF receptor-related proto-oncogene erbB-2 in human mammary tumor cell lines by different molecular mechanisms

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5036860

Distinctive traits of normal and tumor-derived human mammary epithelial cells expressed in a medium that supports long-term growth of both cell types

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5036860

DNA amplification is a ubiquitous mechanism of oncogene activation in lung and other cancers.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5036860

Reproducibility assessment of relative quantitation strategies for LC-MS based proteomics

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5036860

Multidimensional proteome analysis of human mammary epithelial cells

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5036860

Human mammary epithelial cells rapidly exchange empty EGFR between surface and intracellular pools

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5036860

ErbB-2 amplification inhibits down-regulation and induces constitutive activation of both ErbB-2 and epidermal growth factor receptors.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5036860

Western blots versus selected reaction monitoring assays: time to turn the tables?

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5036860

Quantifying Western blots: pitfalls of densitometry.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5036860

Amplification, enhanced expression and possible rearrangement of EGF receptor gene in primary human brain tumours of glial origin.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5036860

Quantitative analysis of the endocytic system involved in hormone-induced receptor internalization

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5036860

High-throughput comparative proteome analysis using a quantitative cysteinyl-peptide enrichment technology.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5036860

Detection of in situ labeled cell surface proteins by mass spectrometry: application to the membrane subproteome of human mammary epithelial cells

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5036860

Blockage of EGF receptor signal transduction causes reversible arrest of normal and immortal human mammary epithelial cells with synchronous reentry into the cell cycle.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5036860

Quantitative analysis of the EGF receptor autocrine system reveals cryptic regulation of cell response by ligand capture

3 September 2018

1 reference

12 December 2020

An accurate mass tag strategy for quantitative and high-throughput proteome measurements

1 reference

12 December 2020

Overexpression of the Grb2 gene in human breast cancer cell lines

1 reference

12 December 2020

Relationship between epidermal growth factor receptor occupancy and mitogenic response. Quantitative analysis using a steady state model system

1 reference

12 December 2020

10.1126/SCISIGNAL.AAF0891

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27405981%20AND%20SRC:MED&resulttype=core&format=json

release_2kg6xd257zaappv3emrspvmcua

10 June 2020

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/2kg6xd257zaappv3emrspvmcua

24 November 2022

mapped directly with Wikidata item

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27405981%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

PubMed publication ID

27405981

1 reference