(Q37306478)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18946474%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

review article

1 reference

title

Crosstalk between small GTPases and polarity proteins in cell polarization (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18946474%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18946474%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

author name string

John G Collard

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18946474%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

publication date

1 November 2008

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18946474%20AND%20SRC:MED&resulttype=core&format=json

Nature Reviews Molecular Cell Biology

24 December 2019

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18946474%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

volume

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18946474%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

issue

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18946474%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

page(s)

846-859

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18946474%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1038/nrm2521

24 December 2019

exact match

0 references

cites work

The PAR proteins: fundamental players in animal cell polarization

1 reference

Polarity complex proteins

31 March 2020

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The Scribble and Par complexes in polarity and migration: friends or foes?

31 March 2020

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Linking Rap to cell adhesion

31 March 2020

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Rho GTPases: biochemistry and biology

31 March 2020

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Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia

31 March 2020

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Rac downregulates Rho activity: reciprocal balance between both GTPases determines cellular morphology and migratory behavior

31 March 2020

1 reference

Redox-dependent downregulation of Rho by Rac.

31 March 2020

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Mechanisms of asymmetric stem cell division

31 March 2020

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Mechanisms of asymmetric cell division: flies and worms pave the way.

31 March 2020

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Identification of genes required for cytoplasmic localization in early C. elegans embryos

31 March 2020

1 reference

Acto-myosin reorganization and PAR polarity in C. elegans

31 March 2020

1 reference

The Rho GTPase-activating proteins RGA-3 and RGA-4 are required to set the initial size of PAR domains in Caenorhabditis elegans one-cell embryos

31 March 2020

1 reference

Dlg, Scrib and Lgl regulate neuroblast cell size and mitotic spindle asymmetry

31 March 2020

1 reference

Dare to be different: asymmetric cell division in Drosophila, C. elegans and vertebrates

31 March 2020

1 reference

The tumour-suppressor genes lgl and dlg regulate basal protein targeting in Drosophila neuroblasts

31 March 2020

1 reference

Role of cortical tumour-suppressor proteins in asymmetric division of Drosophila neuroblast

31 March 2020

1 reference

The Par complex directs asymmetric cell division by phosphorylating the cytoskeletal protein Lgl.

31 March 2020

1 reference

PAR-3 defines a central subdomain of the cortical actin cap in mouse eggs

31 March 2020

1 reference

Asymmetric distribution of PAR proteins in the mouse embryo begins at the 8-cell stage during compaction

31 March 2020

1 reference

Par-complex proteins promote proliferative progenitor divisions in the developing mouse cerebral cortex

31 March 2020

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Asymmetric cell divisions promote stratification and differentiation of mammalian skin

31 March 2020

1 reference

Asymmetric T lymphocyte division in the initiation of adaptive immune responses.

31 March 2020

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Regulators of Rho GTPases in neuronal development.

31 March 2020

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Neuronal polarity: from extracellular signals to intracellular mechanisms

31 March 2020

1 reference

Rho family GTPases and neuronal growth cone remodelling: relationship between increased complexity induced by Cdc42Hs, Rac1, and acetylcholine and collapse induced by RhoA and lysophosphatidic acid

31 March 2020

1 reference

Rac regulates phosphorylation of the myosin-II heavy chain, actinomyosin disassembly and cell spreading

31 March 2020

1 reference

The sequential activity of the GTPases Rap1B and Cdc42 determines neuronal polarity

31 March 2020

1 reference

Evidence for the involvement of Tiam1 in axon formation

31 March 2020

1 reference

Stathmin and its phosphoprotein family: general properties, biochemical and functional interaction with tubulin.

31 March 2020

1 reference

Microtubule stabilization specifies initial neuronal polarization

31 March 2020

1 reference

PAR-6-PAR-3 mediates Cdc42-induced Rac activation through the Rac GEFs STEF/Tiam1.

31 March 2020

1 reference

Ubiquitination of the GTPase Rap1B by the ubiquitin ligase Smurf2 is required for the establishment of neuronal polarity

31 March 2020

1 reference

Role of the PAR-3-KIF3 complex in the establishment of neuronal polarity

31 March 2020

1 reference

The interaction of mPar3 with the ubiquitin ligase Smurf2 is required for the establishment of neuronal polarity

31 March 2020

1 reference

Regulation of cell polarity and protrusion formation by targeting RhoA for degradation

31 March 2020

1 reference

Robust neuronal symmetry breaking by Ras-triggered local positive feedback

31 March 2020

1 reference

R-Ras controls axon specification upstream of glycogen synthase kinase-3beta through integrin-linked kinase

31 March 2020

1 reference

Hippocampal neuronal polarity specified by spatially localized mPar3/mPar6 and PI 3-kinase activity

31 March 2020

1 reference

Regulation of dendritic spine morphology by the rho family of small GTPases: antagonistic roles of Rac and Rho

31 March 2020

1 reference

Role of Rho GTPases in the morphogenesis and motility of dendritic spines.

31 March 2020

1 reference

The polarity protein PAR-3 and TIAM1 cooperate in dendritic spine morphogenesis

31 March 2020

1 reference

The PAR-6 polarity protein regulates dendritic spine morphogenesis through p190 RhoGAP and the Rho GTPase

31 March 2020

1 reference

Activity-dependent dendritic spine structural plasticity is regulated by small GTPase Rap1 and its target AF-6.

31 March 2020

1 reference

Regulation of dendritic spine morphology by SPAR, a PSD-95-associated RapGAP

31 March 2020

1 reference

ICAMs redistributed by chemokines to cellular uropods as a mechanism for recruitment of T lymphocytes

31 March 2020

1 reference

Maintenance and modulation of T cell polarity

31 March 2020

1 reference

Rho GTPases control migration and polarization of adhesion molecules and cytoskeletal ERM components in T lymphocytes

31 March 2020

1 reference

Rac regulates integrin-mediated spreading and increased adhesion of T lymphocytes

31 March 2020

1 reference

Phosphorylation of the LFA-1 Integrin β2-Chain on Thr-758 Leads to Adhesion, Rac-1/Cdc42 Activation, and Stimulation of CD69 Expression in Human T Cells

31 March 2020

1 reference

Roles of p-ERM and Rho-ROCK signaling in lymphocyte polarity and uropod formation.

31 March 2020

1 reference

Rap1 translates chemokine signals to integrin activation, cell polarization, and motility across vascular endothelium under flow

31 March 2020

1 reference

The Par polarity complex regulates Rap1- and chemokine-induced T cell polarization

31 March 2020

1 reference

A Network of PDZ-Containing Proteins Regulates T Cell Polarity and Morphology during Migration and Immunological Synapse Formation

31 March 2020

1 reference

Itk functions to control actin polymerization at the immune synapse through localized activation of Cdc42 and WASP.

31 March 2020

1 reference

ERM proteins regulate cytoskeleton relaxation promoting T cell–APC conjugation

31 March 2020

1 reference

Regulation of a late phase of T cell polarity and effector functions by Crtam

31 March 2020

1 reference

Synapses: sites of cell recognition, adhesion, and functional specification.

31 March 2020

1 reference

Role of Lgl/Dlg/Scribble in the regulation of epithelial junction, polarity and growth

31 March 2020

1 reference

Organization of multiprotein complexes at cell-cell junctions

31 March 2020

1 reference

E-cadherin-mediated cell-cell attachment activates Cdc42

31 March 2020

1 reference

Activation of Cdc42 by trans interactions of the cell adhesion molecules nectins through c-Src and Cdc42-GEF FRG.

31 March 2020

1 reference

Trans-interactions of nectins induce formation of filopodia and Lamellipodia through the respective activation of Cdc42 and Rac small G proteins

31 March 2020

1 reference

PAR-6 regulates aPKC activity in a novel way and mediates cell-cell contact-induced formation of the epithelial junctional complex.

31 March 2020

1 reference

Regulation of cell-cell adhesion by rac and rho small G proteins in MDCK cells

31 March 2020

1 reference

Par-3 controls tight junction assembly through the Rac exchange factor Tiam1.

31 March 2020

1 reference

The Rac activator Tiam1 controls tight junction biogenesis in keratinocytes through binding to and activation of the Par polarity complex

31 March 2020

1 reference

Rac1 orientates epithelial apical polarity through effects on basolateral laminin assembly

31 March 2020

1 reference

Rac1 is required for reorientation of polarity and lumen formation through a PI 3-kinase-dependent pathway.

31 March 2020

1 reference

Tiam1 takes PARt in cell polarity

31 March 2020

1 reference

Cell-polarity dynamics controls the mechanism of lumen formation in epithelial morphogenesis

31 March 2020

1 reference

Cadherin engagement regulates Rho family GTPases

31 March 2020

1 reference

p120-catenin and p190RhoGAP regulate cell-cell adhesion by coordinating antagonism between Rac and Rho.

31 March 2020

1 reference

Localized zones of Rho and Rac activities drive initiation and expansion of epithelial cell-cell adhesion.

31 March 2020

1 reference

Differential roles for actin polymerization and a myosin II motor in assembly of the epithelial apical junctional complex

31 March 2020

1 reference

Actin cable dynamics and Rho/Rock orchestrate a polarized cytoskeletal architecture in the early steps of assembling a stratified epithelium

31 March 2020

1 reference

ROCK and Dia have opposing effects on adherens junctions downstream of Rho

31 March 2020

1 reference

Parallels between tissue repair and embryo morphogenesis

31 March 2020

1 reference

The mammalian Scribble polarity protein regulates epithelial cell adhesion and migration through E-cadherin

31 March 2020

1 reference

A Rich1/Amot complex regulates the Cdc42 GTPase and apical-polarity proteins in epithelial cells

31 March 2020

1 reference

Epithelial-mesenchymal transition: at the crossroads of development and tumor metastasis

31 March 2020

1 reference

Regulation of the polarity protein Par6 by TGFbeta receptors controls epithelial cell plasticity

31 March 2020

1 reference

Downregulation of Par-3 expression and disruption of Par complex integrity by TGF-beta during the process of epithelial to mesenchymal transition in rat proximal epithelial cells

31 March 2020

1 reference

The transcription factor snail represses Crumbs3 expression and disrupts apico-basal polarity complexes

31 March 2020

1 reference

Cell polarity in development and cancer.

31 March 2020

1 reference

Cell polarity and cancer--cell and tissue polarity as a non-canonical tumor suppressor.

31 March 2020

1 reference

Regulation of imaginal disc growth by tumor-suppressor genes in Drosophila

31 March 2020

1 reference

Polarity regulators and the control of epithelial architecture, cell migration, and tumorigenesis.

31 March 2020

1 reference

Mice deficient in the Rac activator Tiam1 are resistant to Ras-induced skin tumours.

31 March 2020

1 reference

31 March 2020

RHO-GTPases and cancer

1 reference

Rho GTPases: functions and association with cancer

31 March 2020

1 reference

The Par-Tiam1 complex controls persistent migration by stabilizing microtubule-dependent front-rear polarity

31 March 2020

1 reference

Cell migration: integrating signals from front to back

31 March 2020

1 reference

Cell migration: Rho GTPases lead the way

31 March 2020

1 reference

Thyroid hormone and astrocyte morphogenesis

31 March 2020

1 reference

Integrin-mediated activation of Cdc42 controls cell polarity in migrating astrocytes through PKCzeta

31 March 2020

1 reference

Cdc42 regulates GSK-3beta and adenomatous polyposis coli to control cell polarity

31 March 2020

1 reference

Cdc42 and Par6-PKCzeta regulate the spatially localized association of Dlg1 and APC to control cell polarization.

31 March 2020

1 reference

Scrib controls Cdc42 localization and activity to promote cell polarization during astrocyte migration

31 March 2020

1 reference

The tumour-suppressor Scribble dictates cell polarity during directed epithelial migration: regulation of Rho GTPase recruitment to the leading edge

31 March 2020

1 reference

PATJ regulates directional migration of mammalian epithelial cells

31 March 2020

1 reference

Numb controls integrin endocytosis for directional cell migration with aPKC and PAR-3.

31 March 2020

1 reference

Nudel binds Cdc42GAP to modulate Cdc42 activity at the leading edge of migrating cells

31 March 2020

1 reference

Rho-kinase phosphorylates PAR-3 and disrupts PAR complex formation.

31 March 2020

1 reference

p190A RhoGAP is a glycogen synthase kinase-3-beta substrate required for polarized cell migration

31 March 2020

1 reference

Cdc42 controls the polarity of the actin and microtubule cytoskeletons through two distinct signal transduction pathways.

31 March 2020

1 reference

Spatiotemporal dynamics of RhoA activity in migrating cells

31 March 2020

1 reference

Targeted deletion of protein kinase C lambda reveals a distribution of functions between the two atypical protein kinase C isoforms

31 March 2020

1 reference

PAR3 is essential for cyst-mediated epicardial development by establishing apical cortical domains.

31 March 2020

1 reference

Rac1 is required for the formation of three germ layers during gastrulation.

31 March 2020

1 reference

Cdc42 is required for PIP(2)-induced actin polymerization and early development but not for cell viability

31 March 2020

1 reference

Targeted disruption of the mouse rho-associated kinase 2 gene results in intrauterine growth retardation and fetal death

31 March 2020

1 reference

Mammalian Crumbs3 is a small transmembrane protein linked to protein associated with Lin-7 (Pals1)

31 March 2020

1 reference

Composition and function of PDZ protein complexes during cell polarization

31 March 2020

1 reference

Photoreceptor cells in flies and mammals: Crumby homology?

31 March 2020

1 reference

Epithelial cell polarity and cell junctions in Drosophila

31 March 2020

1 reference

Multiple regions of Crumbs3 are required for tight junction formation in MCF10A cells

31 March 2020

1 reference

PATJ connects and stabilizes apical and lateral components of tight junctions in human intestinal cells

31 March 2020

1 reference

Cooperative regulation of cell polarity and growth by Drosophila tumor suppressors

31 March 2020

1 reference

Regulation of synapse structure and function by the Drosophila tumor suppressor gene dlg

31 March 2020

1 reference

Recruitment of scribble to the synaptic scaffolding complex requires GUK-holder, a novel DLG binding protein

31 March 2020

1 reference

Regulation of Tiam1-Rac signalling.

31 March 2020

1 reference

Rho GTPases and their effector proteins

31 March 2020

1 reference

Differential requirements for DOCK2 and phosphoinositide-3-kinase gamma during T and B lymphocyte homing

31 March 2020

1 reference

RhoA and microtubule dynamics control cell-basement membrane interaction in EMT during gastrulation

31 March 2020

1 reference

31 March 2020

Identifiers

DOI

10.1038/NRM2521

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18946474%20AND%20SRC:MED&resulttype=core&format=json

release_cdvjdoxhrbbntp63sizw2qw2um

24 December 2019

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/cdvjdoxhrbbntp63sizw2qw2um

mapped directly with Wikidata item

24 November 2022

based on heuristic

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