(Q37309155)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27065235%20AND%20SRC:MED&resulttype=core&format=json

1 April 2020

title

Plant-like biosynthesis of isoquinoline alkaloids in Aspergillus fumigatus (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27065235%20AND%20SRC:MED&resulttype=core&format=json

3-amino-1,7,8,11-tetrahydroxy-1H,2H,3H,6H,11H,11aH-pyrido[1,2-b]isoquinolin-4-one

1 April 2020

main subject

Aspergillus fumigatus

1 reference

inferred from

reverse claim

1 reference

1 reference

1 reference

1 reference

(2S,4S)-4,8-dihydroxy-7,10-dioxo-1,2,3,4,7,10-hexahydrobenzo[c][1,5]naphthyridine-2-carboxylic acid

1 reference

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27065235%20AND%20SRC:MED&resulttype=core&format=json

1 April 2020

Joseph Spraker

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27065235%20AND%20SRC:MED&resulttype=core&format=json

1 April 2020

Henry H Le

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27065235%20AND%20SRC:MED&resulttype=core&format=json

1 April 2020

Frank C Schroeder

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27065235%20AND%20SRC:MED&resulttype=core&format=json

1 April 2020

8

Axel A Brakhage

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27065235%20AND%20SRC:MED&resulttype=core&format=json

1 April 2020

author name string

Eileen Brandenburger

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27065235%20AND%20SRC:MED&resulttype=core&format=json

1 April 2020

Christian Gomez

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27065235%20AND%20SRC:MED&resulttype=core&format=json

1 April 2020

Jin Woo Bok

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27065235%20AND%20SRC:MED&resulttype=core&format=json

1 April 2020

Juliane Macheleidt

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27065235%20AND%20SRC:MED&resulttype=core&format=json

1 April 2020

Dirk Hoffmeister

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27065235%20AND%20SRC:MED&resulttype=core&format=json

1 April 2020

Nancy P Keller

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27065235%20AND%20SRC:MED&resulttype=core&format=json

1 April 2020

publication date

11 April 2016

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27065235%20AND%20SRC:MED&resulttype=core&format=json

full work available at URL

1 April 2020

https://europepmc.org/articles/pmc5049701?pdf=render

1 reference

19 March 2024

https://api.unpaywall.org/v2/10.1038/nchembio.2061?email=unpaywall_01@example.com

published in

Nature Chemical Biology

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27065235%20AND%20SRC:MED&resulttype=core&format=json

1 April 2020

volume

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27065235%20AND%20SRC:MED&resulttype=core&format=json

1 April 2020

issue

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27065235%20AND%20SRC:MED&resulttype=core&format=json

1 April 2020

page(s)

419-424

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27065235%20AND%20SRC:MED&resulttype=core&format=json

1 April 2020

1 reference

19 March 2024

https://api.unpaywall.org/v2/10.1038/nchembio.2061?email=unpaywall_01@example.com

access restriction status

open access

1 reference

inferred from online access status

exact match

https://scigraph.springernature.com/pub.10.1038/nchembio.2061

0 references

cites work

Optimization of yeast-based production of medicinal protoberberine alkaloids.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5049701

Translating biosynthetic gene clusters into fungal armor and weaponry

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5049701

Complete biosynthesis of opioids in yeast

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5049701

An enzyme-coupled biosensor enables (S)-reticuline production in yeast from glucose

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5049701

Transcriptome analysis of cyclic AMP-dependent protein kinase A-regulated genes reveals the production of the novel natural compound fumipyrrole by Aspergillus fumigatus

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5049701

CDD: NCBI's conserved domain database

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5049701

A peptide ligase and the ribosome cooperate to synthesize the peptide pheganomycin

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5049701

Perturbations in small molecule synthesis uncovers an iron-responsive secondary metabolite network in Aspergillus fumigatus

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5049701

A microbial biomanufacturing platform for natural and semisynthetic opioids

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5049701

Aryl-aldehyde formation in fungal polyketides: discovery and characterization of a distinct biosynthetic mechanism

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5049701

Characterization of flavin-based fluorescent proteins: an emerging class of fluorescent reporters

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5049701

Nonproteinogenic amino acid building blocks for nonribosomal peptide and hybrid polyketide scaffolds

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5049701

RsmA regulates Aspergillus fumigatus gliotoxin cluster metabolites including cyclo(L-Phe-L-Ser), a potential new diagnostic marker for invasive aspergillosis

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5049701

Loss of CclA, required for histone 3 lysine 4 methylation, decreases growth but increases secondary metabolite production in Aspergillus fumigatus.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5049701

Benzylisoquinoline alkaloid metabolism: a century of discovery and a brave new world

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5049701

Homologous NRPS-like gene clusters mediate redundant small-molecule biosynthesis in Aspergillus flavus

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5049701

Regulation of fungal secondary metabolism

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5049701

Correlating secondary metabolite production with genetic changes using differential analysis of 2D NMR spectra

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5049701

Recent progress in the metabolic engineering of alkaloids in plant systems

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5049701

Identification of a gene involved in the synthesis of a dipeptidyl peptidase IV inhibitor in Aspergillus oryzae

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5049701

Catalytic and Structural Role of a Conserved Active Site Histidine in Berberine Bridge Enzyme

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5049701

Advances in Aspergillus secondary metabolite research in the post-genomic era

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5049701

6 September 2017

The ATP-grasp enzymes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5049701

A bacterial platform for fermentative production of plant alkaloids

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5049701

NMR-spectroscopic analysis of mixtures: from structure to function

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5049701

Bioinformatic perspectives on NRPS/PKS megasynthases: advances and challenges

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5049701

A concerted mechanism for berberine bridge enzyme

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5049701

Characterization of the atromentin biosynthesis genes and enzymes in the homobasidiomycete Tapinella panuoides

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5049701

Production of benzylisoquinoline alkaloids in Saccharomyces cerevisiae

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5049701

A fungal family of transcriptional regulators: the zinc cluster proteins

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5049701

Assembly-line enzymology for polyketide and nonribosomal Peptide antibiotics: logic, machinery, and mechanisms.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5049701

Chemical aspects of amine oxidation by flavoprotein enzymes

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5049701

LaeA, a regulator of secondary metabolism in Aspergillus spp

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5049701

Crystal Structure of Serine Dehydratase from Rat Liver,

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5049701

Genetic involvement of a cAMP-dependent protein kinase in a G protein signaling pathway regulating morphological and chemical transitions in Aspergillus nidulans

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5049701

A common fold for peptide synthetases cleaving ATP to ADP: glutathione synthetase and D-alanine:d-alanine ligase of Escherichia coli

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5049701

Characterization and Mechanism of the Berberine Bridge Enzyme, a Covalently Flavinylated Oxidase of Benzophenanthridine Alkaloid Biosynthesis in Plants

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5049701

Class of cyclic ribosomal peptide synthetic genes in filamentous fungi

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5049701

Opportunities in metabolic engineering to facilitate scalable alkaloid production

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5049701

Chromatin-level regulation of biosynthetic gene clusters

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5049701

Isotope effects suggest a stepwise mechanism for berberine bridge enzyme

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5049701

Functional and phylogenetic divergence of fungal adenylate-forming reductases

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5049701

Tyrosyl radical formation and propagation in flavin dependent monoamine oxidases.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5049701

LaeA, a regulator of morphogenetic fungal virulence factors.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5049701

Nonribosomal peptide synthetase (NPS) genes in Fusarium graminearum, F. culmorum and F. pseudograminearium and identification of NPS2 as the producer of ferricrocin

2 September 2018

1 reference

12 December 2020

Reconstitution of a 10-gene pathway for synthesis of the plant alkaloid dihydrosanguinarine in Saccharomyces cerevisiae

1 reference

12 December 2020

A one-pot chemoenzymatic synthesis for the universal precursor of antidiabetes and antiviral bis-indolylquinones

1 reference

12 December 2020

beta-Phenylethylamines and the isoquinoline alkaloids

1 reference

12 December 2020

Double-joint PCR: a PCR-based molecular tool for gene manipulations in filamentous fungi

1 reference

12 December 2020

Identifiers

DOI

10.1038/NCHEMBIO.2061

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27065235%20AND%20SRC:MED&resulttype=core&format=json

1 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27065235%20AND%20SRC:MED&resulttype=core&format=json

1 April 2020

PubMed publication ID

27065235

1 reference