(Q37316548)

19 August 2017

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title

Why does cytotoxic chemotherapy cure only some cancers? (English)

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19 August 2017

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Philip Savage

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19 August 2017

Justin Stebbing

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2

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19 August 2017

Mark Bower

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3

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19 August 2017

Tim Crook

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4

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19 August 2017

4 November 2008

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Nature Clinical Practice Oncology

19 August 2017

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19 August 2017

6

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19 August 2017

43-52

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19 August 2017

1

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https://scigraph.springernature.com/pub.10.1038/ncponc1260

19 August 2017

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cites work

Childhood acute lymphoblastic leukaemia--current status and future perspectives

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12 December 2020

Genetic basis of drug sensitivity in human testis tumour cells

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12 December 2020

Apoptosis. Biochemical events and relevance to cancer chemotherapy

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12 December 2020

Apoptosis in gestational trophoblastic disease is correlated with clinical outcome and Bcl-2 expression but not Bax expression

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12 December 2020

Molecular determinants of treatment response in human germ cell tumors

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12 December 2020

Dacarbazine-based chemotherapy for metastatic melanoma: thirty-year experience overview

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12 December 2020

Impaired V(D)J recombination and increased apoptosis among B cell precursors in the bone marrow of c-Abl-deficient mice.

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12 December 2020

Twenty years of MOPP therapy for Hodgkin's disease

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12 December 2020

Antineoplastic agents and pregnancy

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12 December 2020

Diffuse large B-cell lymphoma outcome prediction by gene-expression profiling and supervised machine learning

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12 December 2020

Five-day oral etoposide treatment for advanced small-cell lung cancer: randomized comparison with intravenous chemotherapy.

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12 December 2020

B lineage-specific regulation of V(D)J recombinase activity is established in common lymphoid progenitors

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12 December 2020

Immunoglobulin genes: generating diversity with AID and UNG.

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12 December 2020

Placental site trophoblastic tumor: molecular analysis and clinical experience

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12 December 2020

The mechanism and regulation of chromosomal V(D)J recombination

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12 December 2020

VH mutation status and VDJ rearrangement structure in mantle cell lymphoma: correlation with genomic aberrations, clinical characteristics, and outcome.

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12 December 2020

Low-risk persistent gestational trophoblastic disease: outcome after initial treatment with low-dose methotrexate and folinic acid from 1992 to 2000.

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12 December 2020

DNA repair capacity and cisplatin sensitivity of human testis tumour cells

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12 December 2020

THE ORIGIN OF HODGKIN AND REED/STERNBERG CELLS IN HODGKIN'S DISEASE

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12 December 2020

A medical research council randomized trial of single agent carboplatin versus etoposide and cisplatin for advanced metastatic seminoma. MRC Testicular Tumour Working Party

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12 December 2020

Prognostic significance of anaplastic lymphoma kinase (ALK) protein expression in adults with anaplastic large cell lymphoma.

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12 December 2020

Adenovirus-mediated p53 gene therapy: overview of preclinical studies and potential clinical applications

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12 December 2020

Spontaneous regression of testicular germ cell tumors: an analysis of 42 cases

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12 December 2020

Trastuzumab plus adjuvant chemotherapy for operable HER2-positive breast cancer

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12 December 2020

Randomized phase III study of exatecan and gemcitabine compared with gemcitabine alone in untreated advanced pancreatic cancer

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12 December 2020

Adenovirus p53 gene therapy

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12 December 2020

Advanced Lymphosarcoma: Intensive Cyclical Combination Chemotherapy with Cyclophosphamide, Vincristine, and Prednisone

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12 December 2020

Nodal peripheral T-cell lymphomas and, in particular, their lymphoepithelioid (Lennert's) variant are often derived from CD8(+) cytotoxic T-cells

1 reference

12 December 2020

Cytotoxic-free treatment designs: time to resistance

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12 December 2020

Methotrexate and misoprostol for early abortion: a multicenter trial. I. Safety and efficacy.

1 reference

12 December 2020

Pathways of apoptosis in lymphocyte development, homeostasis, and disease

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12 December 2020

Human testis-determining factor SRY binds to the major DNA adduct of cisplatin and a putative target sequence with comparable affinities.

1 reference

12 December 2020

Management of patients with malignant lymphoma: a comparative study with cyclophosphamide and vinca alkaloids.

1 reference

12 December 2020

Expression of BCL-2, BAX and BAK in the Trophoblast Layer of the Term Human Placenta: a Unique Model of Apoptosis within a Syncytium

1 reference

12 December 2020

The medical management of ectopic pregnancy: a meta-analysis comparing "single dose" and "multidose" regimens

1 reference

12 December 2020

p53 controls low DNA damage-dependent premeiotic checkpoint and facilitates DNA repair during spermatogenesis

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12 December 2020

Proceedings: Malignant lymphoma: treatment with combination chemotherapy

1 reference

12 December 2020

Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia

1 reference

12 December 2020

Treatment of disseminated germ-cell tumors with cisplatin, bleomycin, and either vinblastine or etoposide

1 reference

12 December 2020

Use of chemotherapy during human pregnancy

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12 December 2020

P53, bcl-2 and bax immunoreactivity as predictors of response and outcome after chemotherapy for metastatic germ cell testicular tumours

1 reference

12 December 2020

Human male germ cell tumor resistance to cisplatin is linked to TP53 gene mutation

1 reference

12 December 2020

XAF1 mediates tumor necrosis factor-alpha-induced apoptosis and X-linked inhibitor of apoptosis cleavage by acting through the mitochondrial pathway.

1 reference

12 December 2020

Apoptosis stimulating protein of p53 (ASPP2) expression differs in diffuse large B-cell and follicular center lymphoma: correlation with clinical outcome

1 reference

12 December 2020

Gestational trophoblastic neoplasia management: an update

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12 December 2020

Targeting of somatic hypermutation

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12 December 2020

Aberrant expression of cyclin D2 is an early event in human male germ cell tumorigenesis.

1 reference

12 December 2020

Apoptosis of multiple myeloma.

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12 December 2020

Heterogeneity of protein kinase C beta(2) expression in lymphoid malignancies

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12 December 2020

Recent experience with decitabine in MDS.

1 reference

12 December 2020

The chemotherapy of metastatic seminoma

1 reference

12 December 2020

Clinical characteristics and long-term outcome of patients with generalized patch and/or plaque (T2) mycosis fungoides.

1 reference

12 December 2020

Paclitaxel plus carboplatin versus standard chemotherapy with either single-agent carboplatin or cyclophosphamide, doxorubicin, and cisplatin in women with ovarian cancer: the ICON3 randomised trial

1 reference

12 December 2020

Development of p53 protein transduction therapy using membrane-permeable peptides and the application to oral cancer cells

1 reference

12 December 2020

Expression of the p53 gene and apoptosis in gestational trophoblastic disease

1 reference

12 December 2020

The role of apoptosis in the regulation of trophoblast survival and differentiation during pregnancy

1 reference

12 December 2020

Villous trophoblast of human placenta: a coherent view of its turnover, repair and contributions to villous development and maturation

1 reference

12 December 2020

Apoptosis. Mitochondria--the death signal integrators

1 reference

12 December 2020

Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling

1 reference

12 December 2020

Chemotherapy of metastatic testis cancer. Results in 154 patients

1 reference

12 December 2020

Current treatment options for myeloma

1 reference

12 December 2020

Cyclin D2 is an FSH-responsive gene involved in gonadal cell proliferation and oncogenesis

1 reference

12 December 2020

The addition of rituximab to a combination of fludarabine, cyclophosphamide, mitoxantrone (FCM) significantly increases the response rate and prolongs survival as compared with FCM alone in patients with relapsed and refractory follicular and mantle

1 reference

12 December 2020

Utilization of Ig heavy chain variable, diversity, and joining gene segments in children with B-lineage acute lymphoblastic leukemia: implications for the mechanisms of VDJ recombination and for pathogenesis

1 reference

12 December 2020

Gene expression profiling of B cell chronic lymphocytic leukemia reveals a homogeneous phenotype related to memory B cells.

1 reference

12 December 2020

Malignant ovarian germ cell tumors: identification of novel prognostic markers and long-term outcome after multimodality treatment

1 reference

12 December 2020

B-cell homeostasis: digital survival or analog growth?

1 reference

12 December 2020

Chemotherapy of choriocarcinoma and related trophoblastic tumors in women

1 reference

12 December 2020

The revised International Prognostic Index (R-IPI) is a better predictor of outcome than the standard IPI for patients with diffuse large B-cell lymphoma treated with R-CHOP

1 reference

12 December 2020

Evaluation of single-drug versus multiple-drug chemotherapy in the treatment of advanced breast cancer

1 reference

12 December 2020

A prognostic score for advanced Hodgkin's disease. International Prognostic Factors Project on Advanced Hodgkin's Disease

1 reference

12 December 2020

Inhibition of KIT tyrosine kinase activity: a novel molecular approach to the treatment of KIT-positive malignancies

1 reference

12 December 2020

Expression of PKC-beta or cyclin D2 predicts for inferior survival in diffuse large B-cell lymphoma

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12 December 2020

CHOP chemotherapy plus rituximab compared with CHOP alone in elderly patients with diffuse large-B-cell lymphoma

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12 December 2020

Regulation of germ cell death in mammalian gonads.

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12 December 2020

The very 5' end and the constant region of Ig genes are spared from somatic mutation because AID does not access these regions

1 reference

12 December 2020

Why did p53 gene therapy fail in ovarian cancer?

1 reference

12 December 2020

The expression of 70 apoptosis genes in relation to lineage, genetic subtype, cellular drug resistance, and outcome in childhood acute lymphoblastic leukemia

1 reference

12 December 2020

CHOP-like chemotherapy plus rituximab versus CHOP-like chemotherapy alone in young patients with good-prognosis diffuse large-B-cell lymphoma: a randomised controlled trial by the MabThera International Trial (MInT) Group

1 reference

12 December 2020

Anaplastic large cell lymphomas lack the expression of T-cell receptor molecules or molecules of proximal T-cell receptor signaling

1 reference

12 December 2020

Therapy of choriocarcinoma and related trophoblastic tumors with folic acid and purine antagonists

1 reference

12 December 2020

Hypersensitivity of human testicular tumors to etoposide-induced apoptosis is associated with functional p53 and a high Bax:Bcl-2 ratio.

1 reference

12 December 2020

Apoptosis: a link between cancer genetics and chemotherapy

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12 December 2020

Evidence of a hereditary p53 syndrome in cancer-prone families

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNCPONC1260

7 January 2021

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Identifiers

DOI

10.1038/NCPONC1260

1 reference

Dimensions Publication ID

19 August 2017

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1 reference