(Q37327420)

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Systemic and cerebral exposure to and pharmacokinetics of flavonols and terpene lactones after dosing standardized Ginkgo biloba leaf extracts to rats via different routes of administration.

scientific article published on September 2013

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4 March 2020

Systemic and cerebral exposure to and pharmacokinetics of flavonols and terpene lactones after dosing standardized Ginkgo biloba leaf extracts to rats via different routes of administration (English)

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4 March 2020

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pharmacokinetics

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inferred from title

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4 March 2020

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Li Li

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4 March 2020

Fang Xu

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4 March 2020

Yan Sun

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4 March 2020

Feifei Du

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4 March 2020

Xutao Ma

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4 March 2020

Chenchun Zhong

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4 March 2020

Xiuxue Li

8

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4 March 2020

Fengqing Wang

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4 March 2020

Nating Zhang

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4 March 2020

Chuan Li

11

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4 March 2020

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1 September 2013

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4 March 2020

British Journal of Pharmacology

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4 March 2020

170

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4 March 2020

2

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4 March 2020

440-457

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23808355%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

Curcumin and neurodegenerative diseases: a perspective

1 reference

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6 September 2017

Cerebrovascular disorders: molecular insights and therapeutic opportunities

1 reference

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6 September 2017

Pharmacology in health food: metabolism of quercetin in vivo and its protective effect against arteriosclerosis

1 reference

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6 September 2017

Effects of Ginkgo biloba on cerebral blood flow assessed by quantitative MR perfusion imaging: a pilot study

1 reference

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6 September 2017

Flavonols and cardiovascular disease

1 reference

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6 September 2017

Mechanisms underlying inflammation in neurodegeneration

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6 September 2017

The Ginkgo biloba extract EGb 761(R) and its main constituent flavonoids and ginkgolides increase extracellular dopamine levels in the rat prefrontal cortex

1 reference

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6 September 2017

Quercetin and its major metabolites selectively modulate cyclic GMP-dependent relaxations and associated tolerance in pig isolated coronary artery

1 reference

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6 September 2017

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Effects of insulin and octreotide on memory and growth hormone in Alzheimer's disease

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6 September 2017

Liquid chromatography/atmospheric pressure chemical ionization ion trap mass spectrometry of bilobalide in plasma and brain of rats after oral administration of its phospholipidic complex

1 reference

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6 September 2017

Ginkgo biloba extract neuroprotective action is dependent on heme oxygenase 1 in ischemic reperfusion brain injury.

1 reference

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6 September 2017

Clinical use and molecular mechanisms of action of extract of Ginkgo biloba leaves in cardiovascular diseases

1 reference

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6 September 2017

Improved haemorrheological properties by Ginkgo biloba extract (Egb 761) in type 2 diabetes mellitus complicated with retinopathy

1 reference

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6 September 2017

Pharmacokinetics and bioavailability of herbal medicinal products.

1 reference

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6 September 2017

Inhibition of amyloid-beta aggregation and caspase-3 activation by the Ginkgo biloba extract EGb761

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3834766

6 September 2017

Enterohepatic circulation: physiological, pharmacokinetic and clinical implications

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6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3834766

6 September 2017

Ginkgo biloba extract enhances glucose tolerance in hyperinsulinism-induced hepatic cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3834766

14 September 2017

Bilobalide prevents apoptosis through activation of the PI3K/Akt pathway in SH-SY5Y cells

1 reference

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14 September 2017

Stimulation of neurogenesis and synaptogenesis by bilobalide and quercetin via common final pathway in hippocampal neurons.

1 reference

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14 September 2017

Ginkgo biloba extract EGb 761 increases endothelial nitric oxide production in vitro and in vivo.

1 reference

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14 September 2017

Protection by EGb 761 against beta-amyloid-induced neurotoxicity: involvement of NF-kappaB, SIRT1, and MAPKs pathways and inhibition of amyloid fibril formation

1 reference

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14 September 2017

Combinatorial metabolism notably affects human systemic exposure to ginsenosides from orally administered extract of Panax notoginseng roots (Sanqi).

1 reference

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26 June 2018

Brain permeability of bilobalide as probed by microdialysis before and after middle cerebral artery occlusion in mice.

1 reference

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26 June 2018

Confidence interval criteria for assessment of dose proportionality.

1 reference

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26 June 2018

Nrf-2 mediated heme oxygenase-1 expression, an antioxidant-independent mechanism, contributes to anti-atherogenesis and vascular protective effects of Ginkgo biloba extract.

1 reference

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2 September 2018

EGb761 ameliorates the formation of foam cells by regulating the expression of SR-A and ABCA1: role of haem oxygenase-1.

1 reference

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2 September 2018

Comparative pharmacokinetics and bioavailability studies of quercetin, kaempferol and isorhamnetin after oral administration of Ginkgo biloba extracts, Ginkgo biloba extract phospholipid complexes and Ginkgo biloba extract solid dispersions in rats

1 reference

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Plasma levels and distribution of flavonoids in rat brain after single and repeated doses of standardized Ginkgo biloba extract EGb 761®.

1 reference

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Glucuronidated and sulfated metabolites of the flavonoid quercetin prevent endothelial dysfunction but lack direct vasorelaxant effects in rat aorta.

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EGb 761 enhances adult hippocampal neurogenesis and phosphorylation of CREB in transgenic mouse model of Alzheimer's disease

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Terpene trilactones from Ginkgo biloba are antagonists of cortical glycine and GABA(A) receptors

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Pharmacokinetics of Ginkgo biloba extracts

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Ginkgo biloba extract inhibits tumor necrosis factor-alpha-induced reactive oxygen species generation, transcription factor activation, and cell adhesion molecule expression in human aortic endothelial cells

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Intestinal absorption and presystemic elimination of various chemical constituents present in GBE50 extract, a standardized extract of Ginkgo biloba leaves

1 reference

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12 December 2020

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inferred from PubMed ID database lookup

Absorption, disposition, and pharmacokinetics of herbal medicines: what and how?

1 reference

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12 December 2020

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inferred from PubMed ID database lookup

Physiological parameters in laboratory animals and humans

1 reference

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12 December 2020

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inferred from PubMed ID database lookup

Ginkgo biloba extract improves coronary blood flow in patients with coronary artery disease: role of endothelium-dependent vasodilation

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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10.1111/BPH.12285

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Europe PubMed Central

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4 March 2020

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4 March 2020

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4 March 2020

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