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English
X11alpha haploinsufficiency enhances Abeta amyloid deposition in Alzheimer's disease transgenic mice.
scientific article published on 23 July 2009
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scholarly article
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Europe PubMed Central
PMC publication ID
2742573
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19631749%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 February 2020
title
X11alpha haploinsufficiency enhances Abeta amyloid deposition in Alzheimer's disease transgenic mice
(English)
1 reference
stated in
Europe PubMed Central
PMC publication ID
2742573
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19631749%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 February 2020
main subject
Alzheimer's disease
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haploinsufficiency
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author
Raymond Turner
series ordinal
4
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Europe PubMed Central
PMC publication ID
2742573
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19631749%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 February 2020
author name string
Inderjeet Saluja
series ordinal
1
1 reference
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Europe PubMed Central
PMC publication ID
2742573
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19631749%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 February 2020
Henry Paulson
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2
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Europe PubMed Central
PMC publication ID
2742573
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19631749%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 February 2020
Ashwin Gupta
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3
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Europe PubMed Central
PMC publication ID
2742573
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19631749%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 February 2020
publication date
23 July 2009
1 reference
stated in
Europe PubMed Central
PMC publication ID
2742573
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19631749%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 February 2020
published in
Neurobiology of Disease
1 reference
stated in
Europe PubMed Central
PMC publication ID
2742573
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19631749%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 February 2020
volume
36
1 reference
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Europe PubMed Central
PMC publication ID
2742573
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19631749%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 February 2020
issue
1
1 reference
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Europe PubMed Central
PMC publication ID
2742573
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19631749%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 February 2020
page(s)
162-168
1 reference
stated in
Europe PubMed Central
PMC publication ID
2742573
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19631749%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 February 2020
describes a project that uses
ImageQuant
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Europe PubMed Central
retrieved
11 June 2022
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2742573/fullTextXML
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cites work
Deletion of Mint proteins decreases amyloid production in transgenic mouse models of Alzheimer's disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2742573
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6 September 2017
Membrane microdomain switching: a regulatory mechanism of amyloid precursor protein processing.
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6 September 2017
Role of X11 and ubiquilin as in vivo regulators of the amyloid precursor protein in Drosophila
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2742573
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6 September 2017
Alzheimer disease models and human neuropathology: similarities and differences
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PubMed Central
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6 September 2017
Genetic analysis of Mint/X11 proteins: essential presynaptic functions of a neuronal adaptor protein family
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2742573
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6 September 2017
CASK associates with glutamate receptor interacting protein and signaling molecules
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6 September 2017
The X11 proteins, Abeta production and Alzheimer's disease.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2742573
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6 September 2017
Adaptor protein interactions: modulators of amyloid precursor protein metabolism and Alzheimer's disease risk?
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PubMed Central
reference URL
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6 September 2017
Novel cadherin-related membrane proteins, Alcadeins, enhance the X11-like protein-mediated stabilization of amyloid beta-protein precursor metabolism
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2742573
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6 September 2017
Alzheimer's disease: molecular understanding predicts amyloid-based therapeutics
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2742573
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6 September 2017
Regulation of APP-dependent transcription complexes by Mint/X11s: differential functions of Mint isoforms
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2742573
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6 September 2017
Modulation of amyloid precursor protein metabolism by X11alpha /Mint-1. A deletion analysis of protein-protein interaction domains.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2742573
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6 September 2017
Regulation of X11L-dependent amyloid precursor protein metabolism by XB51, a novel X11L-binding protein
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2742573
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6 September 2017
Mint2/X11-like colocalizes with the Alzheimer's disease amyloid precursor protein and is associated with neuritic plaques in Alzheimer's disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2742573
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6 September 2017
Identification of an evolutionarily conserved heterotrimeric protein complex involved in protein targeting
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2742573
retrieved
6 September 2017
The X11alpha protein slows cellular amyloid precursor protein processing and reduces Abeta40 and Abeta42 secretion
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2742573
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6 September 2017
Mints, Munc18-interacting proteins in synaptic vesicle exocytosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2742573
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6 September 2017
Expression of mDab1 promotes the stability and processing of amyloid precursor protein and this effect is counteracted by X11alpha.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2742573
retrieved
14 September 2017
RNA interference-mediated silencing of X11alpha and X11beta attenuates amyloid beta-protein levels via differential effects on beta-amyloid precursor protein processing.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2742573
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14 September 2017
Cell-type-specific processing of the amyloid precursor protein by Presenilin during Drosophila development.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2742573
retrieved
14 September 2017
X11alpha impairs gamma- but not beta-cleavage of amyloid precursor protein.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2742573
retrieved
14 September 2017
Ultrastructural localization of mint1 at synapses in mouse hippocampus
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2742573
retrieved
14 September 2017
X11 interaction with beta-amyloid precursor protein modulates its cellular stabilization and reduces amyloid beta-protein secretion
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2742573
retrieved
28 September 2017
X11 proteins regulate the translocation of amyloid beta-protein precursor (APP) into detergent-resistant membrane and suppress the amyloidogenic cleavage of APP by beta-site-cleaving enzyme in brain
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2742573
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26 June 2018
Enhanced amyloidogenic metabolism of the amyloid beta-protein precursor in the X11L-deficient mouse brain.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2742573
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2 September 2018
The neuronal adaptor protein X11alpha reduces Abeta levels in the brains of Alzheimer's APPswe Tg2576 transgenic mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2742573
retrieved
2 September 2018
X11alpha modulates secretory and endocytic trafficking and metabolism of amyloid precursor protein: mutational analysis of the YENPTY sequence
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2742573
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2 September 2018
Alteration of methamphetamine-induced striatal dopamine release in mint-1 knockout mice
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2742573
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2 September 2018
Neuronal expression of mint1 and mint2, novel multimodular proteins, in adult murine brain
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2742573
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2 September 2018
LIN-10 is a shared component of the polarized protein localization pathways in neurons and epithelia
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2742573
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2 September 2018
The Neuronal Adaptor Protein X11β Reduces Amyloid β-Protein Levels and Amyloid Plaque Formation in the Brains of Transgenic Mice
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/19631749
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Alzheimer's disease
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/19631749
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1016/J.NBD.2009.07.006
1 reference
stated in
Europe PubMed Central
PMC publication ID
2742573
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19631749%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 February 2020
PMC publication ID
2742573
1 reference
stated in
Europe PubMed Central
PMC publication ID
2742573
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19631749%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 February 2020
PubMed publication ID
19631749
1 reference
stated in
Europe PubMed Central
PMC publication ID
2742573
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19631749%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 February 2020
ResearchGate publication ID
26694919
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