(Q40460851)

English

RNA interference-mediated silencing of X11alpha and X11beta attenuates amyloid beta-protein levels via differential effects on beta-amyloid precursor protein processing.

scientific article published on 7 February 2005

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

RNA interference-mediated silencing of X11alpha and X11beta attenuates amyloid beta-protein levels via differential effects on beta-amyloid precursor protein processing. (English)

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

RNA interference

1 reference

based on heuristic

inferred from title

Rudolph E. Tanzi

3

object named as

Rudolph E Tanzi

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

author name string

Zhongcong Xie

1

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

Donna M Romano

2

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

language of work or name

0 references

publication date

7 February 2005

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

number of pages

9

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based on heuristic

inferred from page(s)

Journal of Biological Chemistry

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

280

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

15

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

15413-15421

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

New frontiers in Alzheimer's disease genetics

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414353200

21 January 2018

gamma-Secretase, Notch, Abeta and Alzheimer's disease: where do the presenilins fit in?

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414353200

21 January 2018

Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414353200

21 January 2018

Identification of a Novel Aspartic Protease (Asp 2) as β-Secretase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414353200

21 January 2018

Cellular mechanisms of beta-amyloid production and secretion

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414353200

21 January 2018

Membrane-anchored aspartyl protease with Alzheimer's disease beta-secretase activity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414353200

21 January 2018

Presenilin-dependent gamma-secretase processing of beta-amyloid precursor protein at a site corresponding to the S3 cleavage of Notch

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414353200

21 January 2018

Characterization of a presenilin-mediated amyloid precursor protein carboxyl-terminal fragment gamma. Evidence for distinct mechanisms involved in gamma -secretase processing of the APP and Notch1 transmembrane domains

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414353200

21 January 2018

Cleavage of amyloid beta peptide during constitutive processing of its precursor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414353200

21 January 2018

Evidence that beta-amyloid protein in Alzheimer's disease is not derived by normal processing

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414353200

21 January 2018

The secretases of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414353200

21 January 2018

Presenilin 1 is linked with gamma-secretase activity in the detergent solubilized state

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414353200

21 January 2018

aph-1 and pen-2 are required for Notch pathway signaling, gamma-secretase cleavage of betaAPP, and presenilin protein accumulation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414353200

21 January 2018

PEN-2 is an integral component of the gamma-secretase complex required for coordinated expression of presenilin and nicastrin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414353200

21 January 2018

Nicastrin modulates presenilin-mediated notch/glp-1 signal transduction and betaAPP processing

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414353200

21 January 2018

Aph-1, Pen-2, and Nicastrin with Presenilin generate an active gamma-Secretase complex

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414353200

21 January 2018

The phosphotyrosine interaction domains of X11 and FE65 bind to distinct sites on the YENPTY motif of amyloid precursor protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414353200

21 January 2018

The intracellular cytoplasmic domain of the Alzheimer's disease amyloid precursor protein interacts with phosphotyrosine-binding domain proteins in the yeast two-hybrid system

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414353200

21 January 2018

Adaptor protein interactions: modulators of amyloid precursor protein metabolism and Alzheimer's disease risk?

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414353200

21 January 2018

The X11alpha protein slows cellular amyloid precursor protein processing and reduces Abeta40 and Abeta42 secretion

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414353200

21 January 2018

X11 interaction with beta-amyloid precursor protein modulates its cellular stabilization and reduces amyloid beta-protein secretion

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414353200

21 January 2018

Mint2/X11-like colocalizes with the Alzheimer's disease amyloid precursor protein and is associated with neuritic plaques in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414353200

21 January 2018

X11 alpha and x11 beta interact with presenilin-1 via their PDZ domains

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414353200

21 January 2018

X11alpha modulates secretory and endocytic trafficking and metabolism of amyloid precursor protein: mutational analysis of the YENPTY sequence

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414353200

21 January 2018

PEN-2 and APH-1 coordinately regulate proteolytic processing of presenilin 1.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414353200

21 January 2018

Hypocapnia induces caspase-3 activation and increases Abeta production

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414353200

21 January 2018

The neuronal adaptor protein X11alpha reduces Abeta levels in the brains of Alzheimer's APPswe Tg2576 transgenic mice

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414353200

21 January 2018

Mints as adaptors. Direct binding to neurexins and recruitment of munc18

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414353200

21 January 2018

Basolateral localization of the Caenorhabditis elegans epidermal growth factor receptor in epithelial cells by the PDZ protein LIN-10.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414353200

21 January 2018

Association of neuronal calcium channels with modular adaptor proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414353200

21 January 2018

Interaction of rat lin-10 with brain-enriched F-actin-binding protein, neurabin-II/spinophilin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414353200

21 January 2018

The neuronal adaptor protein X11alpha interacts with the copper chaperone for SOD1 and regulates SOD1 activity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414353200

21 January 2018

Kinesin superfamily motor protein KIF17 and mLin-10 in NMDA receptor-containing vesicle transport

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414353200

21 January 2018

Identifiers

10.1074/JBC.M414353200

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

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