(Q37427465)

20 August 2017

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title

Specificity of insulin signalling in human skeletal muscle as revealed by small interfering RNA. (English)

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20 August 2017

2

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20 August 2017

A Krook

1

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publication date

31 March 2009

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20 August 2017

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20 August 2017

volume

52

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20 August 2017

issue

7

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20 August 2017

page(s)

1231-1239

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IRS proteins and the common path to diabetes

20 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1007%2FS00125-009-1330-Y

Protein kinase B/Akt participates in GLUT4 translocation by insulin in L6 myoblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-009-1330-Y

WY-14643 and 9- cis-retinoic acid induce IRS-2/PI 3-kinase signalling pathway and increase glucose transport in human skeletal muscle cells: differential effect in myotubes from healthy subjects and Type 2 diabetic patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-009-1330-Y

The effects of lesions in the hypothalamus in parabiotic rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-009-1330-Y

Mechanism by which high-dose aspirin improves glucose metabolism in type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-009-1330-Y

Critical nodes in signalling pathways: insights into insulin action

21 January 2018

1 reference

12 December 2020

Insulin receptor substrate-2 is not necessary for insulin- and exercise-stimulated glucose transport in skeletal muscle

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12 December 2020

Insulin receptor substrate-2 binds to the insulin receptor through its phosphotyrosine-binding domain and through a newly identified domain comprising amino acids 591-786

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12 December 2020

Adipocyte dysfunctions linking obesity to insulin resistance and type 2 diabetes

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12 December 2020

Characterization of signal transduction and glucose transport in skeletal muscle from type 2 diabetic patients

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12 December 2020

Alternative pathway of insulin signalling in mice with targeted disruption of the IRS-1 gene.

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12 December 2020

Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans

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12 December 2020

Technology Insight: small, noncoding RNA molecules as tools to study and treat endocrine diseases

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12 December 2020

Modulation of insulin action.

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12 December 2020

Effects of insulin on peripheral and splanchnic glucose metabolism in noninsulin-dependent (type II) diabetes mellitus

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12 December 2020

Tumor necrosis factor alpha (TNFalpha) stimulates Map4k4 expression through TNFalpha receptor 1 signaling to c-Jun and activating transcription factor 2.

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12 December 2020

Insulin regulation of glucose uptake: a complex interplay of intracellular signalling pathways

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12 December 2020

siRNA-based gene silencing reveals specialized roles of IRS-1/Akt2 and IRS-2/Akt1 in glucose and lipid metabolism in human skeletal muscle

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12 December 2020

Insulin resistance and a diabetes mellitus-like syndrome in mice lacking the protein kinase Akt2 (PKB beta)

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12 December 2020

Impaired expression and insulin-stimulated phosphorylation of Akt-2 in muscle of obese patients with atypical diabetes

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12 December 2020

A central role for JNK in obesity and insulin resistance

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12 December 2020

Technique review: how to use RNA interference

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12 December 2020

The effects of hypothalamics lesions in genetically diabetic mice

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12 December 2020

An RNA interference-based screen identifies MAP4K4/NIK as a negative regulator of PPARgamma, adipogenesis, and insulin-responsive hexose transport

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12 December 2020

Insulin sensitivity: modulation by nutrients and inflammation

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12 December 2020

The functions of animal microRNAs

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12 December 2020

Defective signaling through Akt-2 and -3 but not Akt-1 in insulin-resistant human skeletal muscle: potential role in insulin resistance

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12 December 2020

Use of a novel impermeable biotinylated photolabeling reagent to assess insulin- and hypoxia-stimulated cell surface GLUT4 content in skeletal muscle from type 2 diabetic patients

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12 December 2020

The promises and pitfalls of RNA-interference-based therapeutics

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12 December 2020

Differential contribution of insulin receptor substrates 1 versus 2 to insulin signaling and glucose uptake in l6 myotubes.

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12 December 2020

Therapeutic potential of RNAi in metabolic diseases.

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12 December 2020

Tumor necrosis factor-alpha induces skeletal muscle insulin resistance in healthy human subjects via inhibition of Akt substrate 160 phosphorylation

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12 December 2020

Pathogenesis of type 2 diabetes: tracing the reverse route from cure to cause

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12 December 2020

Early metabolic defects in persons at increased risk for non-insulin-dependent diabetes mellitus.

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12 December 2020

The IKKbeta subunit of IkappaB kinase (IKK) is essential for nuclear factor kappaB activation and prevention of apoptosis

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12 December 2020

Salicylic acid reverses phorbol 12-myristate-13-acetate (PMA)- and tumor necrosis factor alpha (TNFalpha)-induced insulin receptor substrate 1 (IRS1) serine 307 phosphorylation and insulin resistance in human embryonic kidney 293 (HEK293) cells

1 reference

12 December 2020

Reversal of obesity- and diet-induced insulin resistance with salicylates or targeted disruption of Ikkbeta

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12 December 2020

Disruption of IRS-2 causes type 2 diabetes in mice

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12 December 2020

Insulin action and glucose metabolism in nondiabetic control and NIDDM subjects. Comparison using human skeletal muscle cell cultures

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12 December 2020

Structural and biochemical characterization of the KRLB region in insulin receptor substrate-2

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12 December 2020

Akt1/PKBalpha is required for normal growth but dispensable for maintenance of glucose homeostasis in mice

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12 December 2020

siRNA-mediated reduction of inhibitor of nuclear factor-kappaB kinase prevents tumor necrosis factor-alpha-induced insulin resistance in human skeletal muscle

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12 December 2020

The regulation of genes and genomes by small RNAs.

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12 December 2020

Tyr624 and Tyr628 in insulin receptor substrate-2 mediate its association with the insulin receptor

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12 December 2020

The role of insulin receptor signaling in zebrafish embryogenesis

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12 December 2020

Absence of functional insulin receptor substrate-3 (IRS-3) gene in humans.

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12 December 2020

The JNK signal transduction pathway

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12 December 2020

Inflammation and insulin resistance

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12 December 2020

Potential role of protein kinase B in insulin-induced glucose transport, glycogen synthesis, and protein synthesis

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12 December 2020

Insulin-stimulated Akt kinase activity is reduced in skeletal muscle from NIDDM subjects

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12 December 2020

Effects of parabiosis of normal with genetically diabetic mice

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12 December 2020

Development of a novel GLUT4 translocation assay for identifying potential novel therapeutic targets for insulin sensitization

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12 December 2020

Insulin receptor substrate-2 phosphorylation is necessary for protein kinase C zeta activation by insulin in L6hIR cells

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12 December 2020

Phosphorylation of IRS proteins, insulin action, and insulin resistance

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12 December 2020

Expression of a constitutively active Akt Ser/Thr kinase in 3T3-L1 adipocytes stimulates glucose uptake and glucose transporter 4 translocation

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12 December 2020

Insulin-stimulated phosphorylation of a Rab GTPase-activating protein regulates GLUT4 translocation

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12 December 2020

Lipid-induced insulin resistance in human muscle is associated with changes in diacylglycerol, protein kinase C, and IkappaB-alpha

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12 December 2020

PTEN, but not SHIP2, suppresses insulin signaling through the phosphatidylinositol 3-kinase/Akt pathway in 3T3-L1 adipocytes

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12 December 2020

Activation of protein kinase C-zeta by insulin and phosphatidylinositol-3,4,5-(PO4)3 is defective in muscle in type 2 diabetes and impaired glucose tolerance: amelioration by rosiglitazone and exercise

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12 December 2020

5-amino-imidazole carboxamide riboside increases glucose transport and cell-surface GLUT4 content in skeletal muscle from subjects with type 2 diabetes

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12 December 2020

MAP4K4 gene silencing in human skeletal muscle prevents tumor necrosis factor-alpha-induced insulin resistance.

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12 December 2020

Insulin resistance differentially affects the PI 3-kinase- and MAP kinase-mediated signaling in human muscle

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12 December 2020

Phosphoinositide 3-kinase-mediated reduction of insulin receptor substrate-1/2 protein expression via different mechanisms contributes to the insulin-induced desensitization of its signaling pathways in L6 muscle cells

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12 December 2020

Insulin action on glucose transport and plasma membrane GLUT4 content in skeletal muscle from patients with NIDDM.

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12 December 2020

Reduced skeletal muscle inhibitor of kappaB beta content is associated with insulin resistance in subjects with type 2 diabetes: reversal by exercise training

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12 December 2020

Differential role of insulin receptor substrate (IRS)-1 and IRS-2 in L6 skeletal muscle cells expressing the Arg1152 --> Gln insulin receptor

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12 December 2020

Insulin signaling through Akt/protein kinase B analyzed by small interfering RNA-mediated gene silencing

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12 December 2020

Insulin action and insulin resistance in human skeletal muscle

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12 December 2020

Normal insulin-dependent activation of Akt/protein kinase B, with diminished activation of phosphoinositide 3-kinase, in muscle in type 2 diabetes

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12 December 2020

Insulin receptor substrate-1 phosphorylation and phosphatidylinositol 3-kinase activity in skeletal muscle from NIDDM subjects after in vivo insulin stimulation

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12 December 2020

10.1007/S00125-009-1330-Y

Identifiers

DOI

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20 August 2017

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